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Noelle Frey
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Journal Articles

Assessment of Outcomes of Allogeneic Stem Cell Transplantation By Treatment Arm in Newly Diagnosed Measurable Residual Disease Negative Patients with B-Lineage Acute Lymphoblastic Leukemia Randomized to Conventional Chemotherapy +/- Blinatumomab in the ECOG-ACRIN E1910 Phase III National Clinical Trials Network Trial

Michaela Liedtke, Zhuoxin Sun, Mark R. Litzow, Ryan J Mattison, Elisabeth Paietta, Kathryn G. Roberts, Yanming Zhang, Janis Racevskis, Hillard M. Lazarus, Jacob M. Rowe, Daniel A. Arber, Julie Bergeron, Brent L. Wood, Yaqi Zhao, Gang Wu, Ti-Cheng Chang, Wenchao Zhang, Keith W. Pratz, Shira N. Dinner, Noelle Frey, Steven D. Gore, Bhavana Bhatnagar, Ehab L. Atallah, Geoffrey L. Uy, Deepa Jeyakumar, Tara L. Lin, Cheryl L. Willman, Daniel J. DeAngelo, Shejal B. Patel, Michelle A Elliott, Anjali S. Advani, Dimitrios Tzachanis, Pankit Vachhani, Rupali Bhave, Elad Sharon, Richard Little, Harry P. Erba, Richard M. Stone, Selina Luger, Charles G. Mullighan, Martin S. Tallman, Matthew J. Wieduwilt
Journal: Blood
Blood (2024) 144 (Supplement 1): 779.
https://doi.org/10.1182/blood-2024-207557
Published: 2024
Journal Articles

Inconsistent Reporting and Definition of Time-to-Event Endpoints in CAR T Clinical Trials: A Review of the Literature and a Call for Harmonization

Connor B Grady, Yimei Li, Shannon L. Maude, Elizabeth O. Hexner, Noelle Frey, David L. Porter, Wei-Ting Hwang
Journal: Blood
Blood (2024) 144 (Supplement 1): 7805.
https://doi.org/10.1182/blood-2024-202597
Published: 2024
Journal Articles

NGS MRD Negativity on Day 28 after Brexu Cel in Adults with R/R ALL Is Associated with Favorable Progression Free Survival

Yannis K. Valtis, David Nemirovsky, Sean M. Devlin, Gregory W Roloff, Ibrahim Aldoss, Nikeshan Jeyakumar, Katharine Miller, Amy Zhang, Katherine C. Sutherland, Anjali S. Advani, Marlise R. Luskin, Evan C. Chen, Omer Jamy, Michael R. Grunwald, Ibrahim Muhsen, Noam E. Kopmar, Bhagirathbhai Dholaria, Simone E. Dekker, Jessica T. Leonard, George Yaghmour, Stephanie B. Tsai, Wendy Stock, Jozal Moore, Kristen M. O'Dwyer, Aaron C. Logan, Matthew P Connor, Noelle Frey, Evandro Bezerra, Sumithira Vasu, Kaitlyn C Dykes, Minoo Battiwalla, Chenyu Lin, Matthew Ulrickson, Ran Reshef, Ryan D. Cassaday, Laquisha C. Hill, Catherine J. Lee, Vamsi K. Kota, Jacob Boccucci, Joshua Sasine, Akil Merchant, Vinod Pullarkat, Amelia Langston, Talal Hilal, Rawan Faramand, Melhem M. Solh, Tamer Othman, Timothy E O'Connor, Navneet Majhail, Shabaz Malik, Luke Mountjoy, Rasmus T. Hoeg, Caspian H. Oliai, Vishal Gupta, Divya Koura, Muthu V. Kumaran, Marc Schwartz, Veronika Bachanova, Sean I. Tracy, Maria Odstrcil Bobillo, Abdullah Ladha, Clayton Jackson, Vivian Irrizary Gatell, Olalekan O. Oluwole, Michael Daunov, John Mathews, Paul Shaughnessy, Bijal D Shah, Lori Muffly, Jae H. Park
Journal: Blood
Blood (2024) 144 (Supplement 1): 4200.
https://doi.org/10.1182/blood-2024-201610
Published: 2024
Journal Articles

Curing CLL: Long-Term Outcomes of Chronic Lymphocytic Leukemia Patients with at Least One Year of Response to CART-19 Therapy

Benjamin F. Frost, Noelle Frey, Elizabeth O. Hexner, Stephen J. Schuster, Sunita D. Nasta, Alison W Loren, Jakub Svoboda, Daniel J. Landsburg, Bruce Levine, Joseph A. Fraietta, J. Joseph Melenhorst, Elizabeth Veloso, Wei-Ting Hwang, Carl H. June, David L. Porter, Saar Gill
Journal: Blood
Blood (2024) 144 (Supplement 1): 588.
https://doi.org/10.1182/blood-2024-204197
Published: 2024
Journal Articles

Real-World Outcomes of Early Relapsed/Refractory Large B Cell Lymphoma Patients Treated with 2 nd Line CAR T Therapy

Michael Schneider, Elise A. Chong, Stefan K. Barta, Sunita D. Nasta, Jakub Svoboda, Jordan Carter, Michael Roderick Cook, Nasheed Hossain, Stephen J. Schuster, Heather Difilippo, John P Plastaras, Michael Lariviere, Marco Ruella, David L. Porter, Noelle Frey, Daniel J. Landsburg
Journal: Blood
Blood (2024) 144 (Supplement 1): 5123.
https://doi.org/10.1182/blood-2024-202736
Published: 2024
Journal Articles

Addition of Blinatumomab to Consolidation Therapy Among Older Newly Diagnosed Patients (pts) with BCR::ABL1 Negative B-Lineage Acute Lymphoblastic Leukemia (ALL) in the ECOG-ACRIN E1910 Randomized Phase III Trial

Nikolai A. Podoltsev, Zhuoxin Sun, Mark R. Litzow, Elisabeth Paietta, Kathryn G. Roberts, Yanming Zhang, Janis Racevskis, Hillard M. Lazarus, Jacob M. Rowe, Daniel A. Arber, Matthew J. Wieduwilt, Michaela Liedtke, Julie Bergeron, Brent L. Wood, Yaqi Zhao, Gang Wu, Ti-Cheng Chang, Wenchao Zhang, Keith W. Pratz, Shira N. Dinner, Noelle Frey, Steven D. Gore, Bhavana Bhatnagar, Ehab L. Atallah, Geoffrey L. Uy, Deepa Jeyakumar, Tara L. Lin, Cheryl L. Willman, Daniel J. DeAngelo, Shejal B. Patel, Michelle A Elliott, Anjali S. Advani, Dimitrios Tzachanis, Pankit Vachhani, Rupali Roy, Elad Sharon, Richard Little, Harry Erba, Richard M. Stone, Charles G. Mullighan, Martin S. Tallman, Selina Luger, Ryan J Mattison
Journal: Blood
Blood (2024) 144 (Supplement 1): 4211.
https://doi.org/10.1182/blood-2024-207143
Published: 2024
Journal Articles

BTK Inhibition Prevents the Induction of Myeloid-Derived Suppressor Cells in Malignancy and Improves CART Function

Benjamin F. Frost, Olga Shestova, Sara Sleiman, Brandon Simone, Feng Shen, Miroslaw Kozlowski, Michelle Wang, J. Joseph Melenhorst, Noelle Frey, Elizabeth O. Hexner, Megan M. Davis, Joseph A. Fraietta, Avery Gaymon, Rong Xu, Chia Sharpe, John C. Byrd, Mark O'Hara, Adam D. Cohen, Stephen J. Schuster, Donald L. Seigel, Carl H. June, David L. Porter, Saar Gill
Journal: Blood
Blood (2024) 144 (Supplement 1): 909.
https://doi.org/10.1182/blood-2024-202659
Published: 2024
Journal Articles

Comparison of CRS- and Icans-Related Outcomes for Large B Cell Lymphoma Patients Treated with Commercial Axicabtagene Ciloleucel with or without Prophylactic Dexamethasone

Alison Carulli, Hayden Elliott, Brendan Mangan, James Whittenburg, Elise A. Chong, Sunita D. Nasta, Jakub Svoboda, Stefan K. Barta, David L. Porter, Jordan S. Carter, Michael Roderick Cook, Nasheed Hossain, Saar Gill, Alfred L. Garfall, Christopher Catania, Colleen R. Kucharczuk, Stephen J. Schuster, Noelle Frey, Daniel J. Landsburg
Journal: Blood
Blood (2024) 144 (Supplement 1): 2275.
https://doi.org/10.1182/blood-2024-203726
Published: 2024
Journal Articles

Efficacy and Safety of Brexucabtagene Autoleucel for Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia in Patients Aged 60 and Above

Ibrahim Muhsen, Anjali S. Advani, Gregory W Roloff, Nikeshan Jeyakumar, Katharine Miller, Amy Zhang, Katherine C. Sutherland, Michael R. Grunwald, Vamsi K. Kota, Jacob Boccucci, Matthew Ulrickson, Joshua Sasine, Ibrahim Aldoss, Tamer Othman, Sumithira Vasu, Ran Reshef, Marlise R. Luskin, Evan C. Chen, Chenyu Lin, Amelia Langston, Ryan D. Cassaday, Noam E. Kopmar, Stephanie B. Tsai, Timothy E O'Connor, Talal Hilal, Rawan Faramand, Jae H. Park, Yannis K. Valtis, Melhem M. Solh, Evandro Bezerra, Jessica T. Leonard, Simone E. Dekker, Navneet Majhail, Minoo Battiwalla, Shahbaz A. Malik, John Mathews, Paul Shaughnessy, Luke Mountjoy, Rasmus T. Hoeg, Caspian H. Oliai, Vishal Gupta, Divya Koura, Kaitlyn C Dykes, Aaron C. Logan, Muthu V. Kumaran, Wendy Stock, Marc Schwartz, Veronika Bachanova, Sean Tracy, Kristen M. O'Dwyer, Jozal Moore, Catherine J. Lee, Maria Silvina Odstrcil Bobillo, Noelle Frey, Matthew P Connor, Omer Jamy, Michael Daunov, Abdullah Ladha, George Yaghmour, Clayton Jackson, Vivian Irrizary Gatell, Olalekan O. Oluwole, Bhagirathbhai Dholaria, Vinod Pullarkat, Akil Merchant, Bijal D Shah, Lori Muffly, LaQuisa Hill
Journal: Blood
Blood (2024) 144 (Supplement 1): 523.
https://doi.org/10.1182/blood-2024-210682
Published: 2024
Journal Articles

Treating Relapsed / Refractory (RR) AML with Biodegradable Anti-CD123 CAR Modified T Cells

Katherine D Cummins, BMBS, Noelle Frey, MD, Anne Marie Nelson, Aliza Schmidt, MS, Selina Luger, MD FRCPC, Randi E. Isaacs, MD, Simon F Lacey, PhD BS, Elizabeth Hexner, MDMS, J. Joseph Melenhorst, PhD, Carl H June, MD, David L Porter, MD, Saar I Gill, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1359.
https://doi.org/10.1182/blood.V130.Suppl_1.1359.1359
Published: 2017
Journal Articles

Durable Remissions with Humanized CD19-Targeted Chimeric Antigen Receptor (CAR)-Modified T Cells in CAR-Naive and CAR-Exposed Children and Young Adults with Relapsed/Refractory Acute Lymphoblastic Leukemia

Shannon L Maude, MD PhD, George E Hucks, Colleen Callahan, Diane Baniewicz, Christina Fasano, Christine Barker, Susan R. Rheingold, MD, Richard Aplenc, MD, Amanda M. Dinofia, MD, Amanda Li, MD BSc, David T Teachey, MD, David M. Barrett, Jennifer Brogdon, PhD, Regina M Young, PhD, John Scholler, Katherine T Marcucci, PhD, Bruce L Levine, PhD, Noelle Frey, MD, David L Porter, MD, Simon F Lacey, PhD BS, J. Joseph Melenhorst, PhD, Carl H June, MD, Stephan A Grupp, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1319.
https://doi.org/10.1182/blood.V130.Suppl_1.1319.1319
Published: 2017
Journal Articles

Clinical Efficacy of Anti-CD22 Chimeric Antigen Receptor T Cells for B-Cell Acute Lymphoblastic Leukemia Is Correlated with the Length of the Scfv Linker and Can be Predicted Using Xenograft Models

Marco Ruella, MD, Shannon L Maude, MD PhD, Boris Engels, PhD, David M. Barrett, Noelle Frey, MD, Katherine T Marcucci, PhD, Olga Shestova, PhD, Nathan Singh, MD, Jessica Perazzelli, PhD, David A Christian, PhD, Dana Haagen, BS, Simon F Lacey, PhD BS, J. Joseph Melenhorst, PhD, Jennifer Brogdon, PhD, Regina M Young, PhD, David L Porter, MD, Carl H June, MD, Stephan A Grupp, MD PhD, Saar I. Gill, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 807.
https://doi.org/10.1182/blood.V130.Suppl_1.807.807
Published: 2017
Journal Articles

Cellular kinetics of CTL019 in relapsed/refractory B-cell acute lymphoblastic leukemia and chronic lymphocytic leukemia

Karen Thudium Mueller, Shannon L. Maude, David L. Porter, Noelle Frey, Patricia Wood, Xia Han, Edward Waldron, Abhijit Chakraborty, Rakesh Awasthi, Bruce L. Levine, J. Joseph Melenhorst, Stephan A. Grupp, Carl H. June, Simon F. Lacey
Journal: Blood
Blood (2017) 130 (21): 2317–2325.
https://doi.org/10.1182/blood-2017-06-786129
Published: 2017
Includes: Supplemental data
Journal Articles

Biomarker Profiling Differentiates Sepsis from Cytokine Release Syndrome in Chimeric Antigen Receptor T-Cell Therapy for Acute Lymphoblastic Leukemia (ALL)

Simon F. Lacey, PhD, Pamela A Shaw, PhD, David T Teachey, MD, Scott L. Weiss, MD, Fang Chen, PhD, Vanessa E Gonzalez, M.B.A, Noelle Frey, MD MS, David L Porter, MD, Shannon L Maude, MD PhD, Stephan A Grupp, MD PhD, Edward Pequignot, M.S., Carl H June, MD, Jan J. Melenhorst, PhD
Journal: Blood
Blood (2016) 128 (22): 2812.
https://doi.org/10.1182/blood.V128.22.2812.2812
Published: 2016
Journal Articles

Biomarkers of Response to Anti-CD19 Chimeric Antigen Receptor (CAR) T-Cell Therapy in Patients with Chronic Lymphocytic Leukemia

Joseph A. Fraietta, PhD, Simon F. Lacey, PhD, Nicholas S Wilcox, Felipe Bedoya, PhD, Fang Chen, PhD, Elena Orlando, PhD, Jennifer L Brogdon, PhD, Wei-Ting Hwang, PhD, Noelle Frey, MD MS, Regina M Young, PhD, Edward Pequignot, M.S., David E Ambrose, BS, Bruce L Levine, PhD, Hans Bitter, PhD, David L Porter, MD, Jun Xu, PhD, Carl H June, MD, Jan Joseph Melenhorst, PhD
Journal: Blood
Blood (2016) 128 (22): 57.
https://doi.org/10.1182/blood.V128.22.57.57
Published: 2016
Journal Articles

Efficacy of Humanized CD19-Targeted Chimeric Antigen Receptor (CAR)-Modified T Cells in Children and Young Adults with Relapsed/Refractory Acute Lymphoblastic Leukemia

Shannon L Maude, MD PhD, David M. Barrett, MD PhD, Susan R. Rheingold, MD, Richard Aplenc, MD PhD, David T Teachey, MD, Colleen Callahan, MSN, Diane Baniewicz, MSN, Claire White, BSN, Mala K. Talekar, MD, Pamela A Shaw, PhD, Jennifer L Brogdon, PhD, Regina M Young, PhD, John Scholler, Katherine T. Marcucci, PhD, Bruce L Levine, PhD, Noelle Frey, MD MS, David L Porter, MD, Simon F. Lacey, PhD, J. Joseph Melenhorst, PhD, Carl H June, MD, Stephan A. Grupp, MD PhD
Journal: Blood
Blood (2016) 128 (22): 217.
https://doi.org/10.1182/blood.V128.22.217.217
Published: 2016
Journal Articles

Cellular Kinetics of Chimeric Antigen Receptor T Cells (CTL019) in Patients with Relapsed/Refractory CD19+ Leukemia

Karen Thudium Mueller, PharmD, MS, Abhijit Chakraborty, PhD, Patricia A Wood, MD PhD, Rakesh Awasthi, BPharm, Alfonso Quintas-Cardama, MD, Xia Han, MS, Shannon L Maude, MD PhD, Stephan A. Grupp, MD PhD, David L Porter, MD, Noelle Frey, MD MS, Katherine T. Marcucci, PhD, Bruce L Levine, PhD, Jan J. Melenhorst, PhD, Carl H June, MD, Simon F. Lacey, PhD
Journal: Blood
Blood (2016) 128 (22): 220.
https://doi.org/10.1182/blood.V128.22.220.220
Published: 2016
Journal Articles

Pilot Study of Anti-CD19 Chimeric Antigen Receptor T Cells (CTL019) in Conjunction with Salvage Autologous Stem Cell Transplantation for Advanced Multiple Myeloma

Alfred L. Garfall, MD, Edward A Stadtmauer, MD, Marcela V. Maus, MD PhD, Wei-Ting Hwang, PhD, Dan T. Vogl, MD, Adam D. Cohen, MD, Brendan M Weiss, MD, David L Porter, MD, Noelle Frey, MD MS, Michael Milone, MD PhD, Patricia Mangan, MSN, CRNP, Maria Krevvata, PhD, Emily Ayers, MD, Karen Dengel, BSN, RN, Naseem DS Kerr, MPH, Simon F. Lacey, PhD, Jan Joseph Melenhorst, PhD, David E Ambrose, BS, Fang Chen, PhD, Vanessa E Gonzalez, M.B.A, Irina Kulikovskaya, PhD, Minnal Gupta, MSc, Jeffrey Finklestein, MSc, Anne Lamontagne, MSc, Matthew O'Rourke, MSc, Megan Suhoski Davis, PhD, Alexander Malykhin, MSc, Bruce L Levine, PhD, Carl H June, MD
Journal: Blood
Blood (2016) 128 (22): 974.
https://doi.org/10.1182/blood.V128.22.974.974
Published: 2016
Journal Articles

Unrelated Donors Are Associated with Improved Relapse Free Survival Compared to Related Donors in Patients with Myelodysplastic Syndrome Undergoing Reduced Intensity Conditioned Allogeneic Stem-Cell Transplantation

Clinton Yam, MBBS, Lisa Crisalli, BS, Selina Luger, MD, Alison Loren, MD MS, Elizabeth O Hexner, MD, Noelle Frey, MD, James Mangan, MD PhD, Amy Gao, MS, Edward A. Stadtmauer, MD, David Porter, MD, Ran Reshef, MD
Journal: Blood
Blood (2015) 126 (23): 4380.
https://doi.org/10.1182/blood.V126.23.4380.4380
Published: 2015
Journal Articles

Autologous Stem Cell Transplantation in First Complete Remission May Not Extend Progression Free Survival in Patients with ALK-Negative Peripheral T Cell Lymphoma

Clinton Yam, MBBS, Daniel J. Landsburg, MD, Xinyi Lin, PhD, Anthony Mato, MD, Jakub Svoboda, MD, Alison Loren, MD MS, Noelle Frey, MD, Edward A. Stadtmauer, MD, David Porter, MD, Stephen J. Schuster, MD, Sunita Dwivedy Nasta, MD
Journal: Blood
Blood (2015) 126 (23): 3183.
https://doi.org/10.1182/blood.V126.23.3183.3183
Published: 2015