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Akil Merchant
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Journal Articles

ALPHA3, a Pivotal Phase 2 Study of First-Line Consolidation with Cemacabtagene Ansegedleucel (Cema-Cel) in Patients with Large B-Cell Lymphoma and Minimal Residual Disease after Response to Standard Therapy

Jason R. Westin, Alex F. Herrera, Ryan Lynch, Jeremy S. Abramson, Don A. Stevens, Matthew Matasar, Lindsey Fitzgerald, Alan P Skarbnik, Chaitanya Iragavarapu, James H Essell, Bradley D. Hunter, Akil Merchant, Indumathy Varadarajan, Anand Tandra, Edward Licitra, Locke Johnson Bryan, Rushang D. Patel, Rajesh Behl, Jeff P. Sharman, Houston Holmes, Habte A. Yimer, Mitul Gandhi, Nosha Farhadfar, Nancy L. Bartlett, Michael Leukam, Tahir Latif, Paolo Caimi, Jean Yared, Amy Feng, Lynn Navale, Sri Ghatta, John B. Le Gall, Zachary J Roberts, John M. Burke
Journal: Blood
Blood (2024) 144 (Supplement 1): 3132.1.
https://doi.org/10.1182/blood-2024-194909
Published: 2024
Journal Articles

Sumoylation As a Novel Target for T-Cell Neoplasms

Larry Milshteyn, Joseph Lownik, Anton Villamejor, Akil Merchant
Journal: Blood
Blood (2024) 144 (Supplement 1): 6535.
https://doi.org/10.1182/blood-2024-211242
Published: 2024
Journal Articles

Comparison of Tacrolimus/Methotrexate and Post-Transplant Cyclophosphamide Graft-Versus Host Disease Prophylaxis for Haploidentical and Matched Allogeneic Stem Cell Transplantation Demonstrates Improved Overall Survival and Reduced Mortality, Shorter Length of Stay, Less Peritransplant Toxicity with Post-Transplant Cyclophosphamide

Noah Merin, Haein Kim, Yuliya Linhares, Akil Merchant, Justin M. Darrah, Joshua Sasine, Hannah Lee, Robert Allen Vescio, David Oveisi, Brittany McGalliard, Ali Rejali, Patricia VanStrien, Ellen B. Klapper, Behrooz Hakimian, John Chute, Ronald Paquette
Journal: Blood
Blood (2024) 144 (Supplement 1): 2104.
https://doi.org/10.1182/blood-2024-202176
Published: 2024
Journal Articles

Efficacy and Safety of Brexucabtagene Autoleucel for Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia in Patients Aged 60 and Above

Ibrahim Muhsen, Anjali S. Advani, Gregory W Roloff, Nikeshan Jeyakumar, Katharine Miller, Amy Zhang, Katherine C. Sutherland, Michael R. Grunwald, Vamsi K. Kota, Jacob Boccucci, Matthew Ulrickson, Joshua Sasine, Ibrahim Aldoss, Tamer Othman, Sumithira Vasu, Ran Reshef, Marlise R. Luskin, Evan C. Chen, Chenyu Lin, Amelia Langston, Ryan D. Cassaday, Noam E. Kopmar, Stephanie B. Tsai, Timothy E O'Connor, Talal Hilal, Rawan Faramand, Jae H. Park, Yannis K. Valtis, Melhem M. Solh, Evandro Bezerra, Jessica T. Leonard, Simone E. Dekker, Navneet Majhail, Minoo Battiwalla, Shahbaz A. Malik, John Mathews, Paul Shaughnessy, Luke Mountjoy, Rasmus T. Hoeg, Caspian H. Oliai, Vishal Gupta, Divya Koura, Kaitlyn C Dykes, Aaron C. Logan, Muthu V. Kumaran, Wendy Stock, Marc Schwartz, Veronika Bachanova, Sean Tracy, Kristen M. O'Dwyer, Jozal Moore, Catherine J. Lee, Maria Silvina Odstrcil Bobillo, Noelle Frey, Matthew P Connor, Omer Jamy, Michael Daunov, Abdullah Ladha, George Yaghmour, Clayton Jackson, Vivian Irrizary Gatell, Olalekan O. Oluwole, Bhagirathbhai Dholaria, Vinod Pullarkat, Akil Merchant, Bijal D Shah, Lori Muffly, LaQuisa Hill
Journal: Blood
Blood (2024) 144 (Supplement 1): 523.
https://doi.org/10.1182/blood-2024-210682
Published: 2024
Journal Articles

Tumor Microenvironment Differences between Diagnostic and Relapsed Classic Hodgkin Lymphoma Revealed By Single Cell Transcriptome Sequencing

Yifan Yin, Tomohiro Aoki, Shinya Rai, Aixiang Jiang, Alexander Xu, Luke O'Brien, Jan Delabie, Lauren Camille Chong, Stacy Hung, Akil Merchant, David W. Scott, Kerry J. Savage, Christian Steidl
Journal: Blood
Blood (2024) 144 (Supplement 1): 646.
https://doi.org/10.1182/blood-2024-209760
Published: 2024
Journal Articles

Characterization of the Tumor Microenvironment of Diagnostic Bone Marrow Core Biopsies from African American Multiple Myeloma Patients Using Imaging Mass Cytometry

Anthony Colombo, Esther Lam, Ben Falk, Anton Luis Villamejor, Amie Hwang, Jose Aparicio, Jia Yin Wan, Chun R. Chao, Mallory Bernstein, Ravi Vij, Mark Fiala, Pei Lin, Robert Z. Orlowski, Imran Siddiqi, David Conti, Akil Merchant, Wendy Cozen
Journal: Blood
Blood (2024) 144 (Supplement 1): 3327.
https://doi.org/10.1182/blood-2024-208818
Published: 2024
Journal Articles

Concurrent Blinatumomab and Human Leukocyte Antigen-Mismatched Cellular Therapy in Patients with High-Risk B-Cell Acute Lymphoblastic Leukemia, a Phase I Prospective Cohort Study

Noah Merin, Haein Kim, Joseph Lownik, Larry Milshteyn, Justin Darrah, Ronald Paquette, Akil Merchant
Journal: Blood
Blood (2024) 144 (Supplement 1): 4202.
https://doi.org/10.1182/blood-2024-211953
Published: 2024
Journal Articles

Multiplex Analysis of Peripheral Blood in Cancer Patients Predicts Humoral and Cellular Responses to Sars-Cov-2 Vaccines

Maryam Kazerani, Simeon Mahov, Joslyn Foley, Noah Merin, So Yung Choi, Joseph Lownik, Alexander Xu, Larry Milshteyn, Anton Luis Villamejor, Maimoona Nadri, Nathalie Nguyen, Omid Hamid, Justin M. Darrah, Jun Gong, Ronald Paquette, Alain Mita, Robert Allen Vescio, Inderjit Mehmi, Warren Tourtellotte, V Krishnan Ramanujan, Karen Reckamp, Jane Figueiredo, Akil Merchant
Journal: Blood
Blood (2024) 144 (Supplement 1): 3922.
https://doi.org/10.1182/blood-2024-208261
Published: 2024
Journal Articles

First Results of IMPT-314, an Autologous Bispecific CD19/CD20 Chimeric Antigen Receptor (CAR) in Enriched Naive and Central Memory T Cells, for the Treatment of Large B Cell Lymphoma (LBCL)

Sarah M. Larson, Umar Farooq, Boyu Hu, Tahir Latif, Felix A. Mensah, Deepthi Kolli, Giulia Parisi, Greg P. Kaufman, Jonathan E. Benjamin, Akil Merchant
Journal: Blood
Blood (2024) 144 (Supplement 1): 4824.
https://doi.org/10.1182/blood-2024-200697
Published: 2024
Journal Articles

NGS MRD Negativity on Day 28 after Brexu Cel in Adults with R/R ALL Is Associated with Favorable Progression Free Survival

Yannis K. Valtis, David Nemirovsky, Sean M. Devlin, Gregory W Roloff, Ibrahim Aldoss, Nikeshan Jeyakumar, Katharine Miller, Amy Zhang, Katherine C. Sutherland, Anjali S. Advani, Marlise R. Luskin, Evan C. Chen, Omer Jamy, Michael R. Grunwald, Ibrahim Muhsen, Noam E. Kopmar, Bhagirathbhai Dholaria, Simone E. Dekker, Jessica T. Leonard, George Yaghmour, Stephanie B. Tsai, Wendy Stock, Jozal Moore, Kristen M. O'Dwyer, Aaron C. Logan, Matthew P Connor, Noelle Frey, Evandro Bezerra, Sumithira Vasu, Kaitlyn C Dykes, Minoo Battiwalla, Chenyu Lin, Matthew Ulrickson, Ran Reshef, Ryan D. Cassaday, Laquisha C. Hill, Catherine J. Lee, Vamsi K. Kota, Jacob Boccucci, Joshua Sasine, Akil Merchant, Vinod Pullarkat, Amelia Langston, Talal Hilal, Rawan Faramand, Melhem M. Solh, Tamer Othman, Timothy E O'Connor, Navneet Majhail, Shabaz Malik, Luke Mountjoy, Rasmus T. Hoeg, Caspian H. Oliai, Vishal Gupta, Divya Koura, Muthu V. Kumaran, Marc Schwartz, Veronika Bachanova, Sean I. Tracy, Maria Odstrcil Bobillo, Abdullah Ladha, Clayton Jackson, Vivian Irrizary Gatell, Olalekan O. Oluwole, Michael Daunov, John Mathews, Paul Shaughnessy, Bijal D Shah, Lori Muffly, Jae H. Park
Journal: Blood
Blood (2024) 144 (Supplement 1): 4200.
https://doi.org/10.1182/blood-2024-201610
Published: 2024
Journal Articles

Development and Characterization of a Novel Murine Peripheral T-Cell Lymphoma Cell Line Which Closely Mimics Human Disease

Larry Milshteyn, Joseph Lownik, Anton Villamejor, Akil Merchant
Journal: Blood
Blood (2023) 142 (Supplement 1): 3021.
https://doi.org/10.1182/blood-2023-188299
Published: 2023
Journal Articles

Metabolic Reprograming of Exhausted Intratumoral CD8+ T-Cell Underlies Anti-Tumor Activity of Sumoylation Inhibitors in Large B Cell Lymphoma

Joseph Lownik, Larry Milshteyn, Anton Villamejor, Jude Canon, Akil Merchant
Journal: Blood
Blood (2023) 142 (Supplement 1): 3009.
https://doi.org/10.1182/blood-2023-188238
Published: 2023
Journal Articles

Integrative Analysis of Genetic and Tumor Microenvironment Topology to Delineate Prognostic Subtypes in Mantle Cell Lymphoma

Sunandini Sharma, Alyssa C. Bouska, Alicia Gamboa, Roshia Ali, Issa Ismail Issa, Waseem G. Lone, Dylan T. Jochum, Weiwei Zhang, Salma Elhag, Dario Ghersi, Dalia ElGamal, Julie M. Vose, Chengfeng Bi, Akil Merchant, Javeed Iqbal
Journal: Blood
Blood (2022) 140 (Supplement 1): 3601–3602.
https://doi.org/10.1182/blood-2022-169933
Published: 2022
Journal Articles

Spatial Tumor Microenvironment Characterization and Outcome of Relapsed/Refractory Classic Hodgkin Lymphoma

Tomohiro Aoki, Aixiang Jiang, Alexander Xu, Alicia Gamboa, Yifan Yin, Katy Milne, Celia Strong, Talia Goodyear, Shaocheng Wu, Lauren C. Chong, Katsuyoshi Takata, Elizabeth Chavez, Tomoko Miyata-Takata, Anthony R. Colombo, Monirath Hav, Adele Telenius, Susana Ben-Neriah, Andrew P. Weng, Kerry J. Savage, David W. Scott, Andrew Roth, Pedro Farinha, Brad H Nelson, Akil Merchant, Christian Steidl
Journal: Blood
Blood (2022) 140 (Supplement 1): 170–171.
https://doi.org/10.1182/blood-2022-158709
Published: 2022
Journal Articles

Phase 2 Randomized, Open-Label, Multicenter Study to Evaluate the Efficacy and Safety of Plamotamab Combined with Tafasitamab (Tafa) + Lenalidomide (Len) Vs Tafa+Len in Relapsed or Refractory DLBCL

Krish Patel, Youngil Koh, Sabarish Ayyappan, Yasmin Karimi, Izidore S. Lossos, Akil Merchant, Phuong Lee, Jianhua Jin, Raphael Clynes, Jitendra Kanodia, Michael T. Chiarella, Steve Kye, Jean-Marie Michot
Journal: Blood
Blood (2022) 140 (Supplement 1): 12066–12067.
https://doi.org/10.1182/blood-2022-158042
Published: 2022
Journal Articles

Spatial Protein Analysis of the Tumor Microenvironment and Biomarkers in Hodgkin's Lymphoma

Alexander Xu, Tomohiro Aoki, Aixiang Jiang, Alicia Gamboa, Anthony R. Colombo, Christian Steidl, Akil Merchant
Journal: Blood
Blood (2022) 140 (Supplement 1): 3564–3565.
https://doi.org/10.1182/blood-2022-170737
Published: 2022
Journal Articles

A Pilot/Safety Study of sEphB4-Hsa in Combination with a Hypomethylating Agent for Patients with Relapsed or Refractory Myelodysplastic Syndrome and Acute Myeloid Leukemia Previously Treated with a Hypomethylating Agent

Caitlin O'Neill, MD, Akil Merchant, MD, Parkash S. Gill, MD, Casey L. O'Connell, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 40–41.
https://doi.org/10.1182/blood-2020-141340
Published: 2020
Journal Articles

Highly Multiplexed Single Cell Spatial Analysis of the Tumor Microenvironment in Lymphoma Predicts Clinical Outcomes

Monirath Hav, PhD, Anthony Colombo, MS, Erik Gerdtsson, MS, Mohan Singh, PhD, Denaly Chen, MD, James Hicks, PhD, Peter Kuhn, PhD, Imran Siddiqi, MD PhD, Akil Merchant, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2789.
https://doi.org/10.1182/blood-2019-130831
Published: 2019
Journal Articles

Single Cell Transcriptome Analysis Reveals Disease-Defining T Cell Subsets in the Tumor Microenvironment of Classic Hodgkin Lymphoma

Tomohiro Aoki, MD PhD, Lauren C. Chong, MSc, Katsuyoshi Takata, MD PhD, Katy Milne, Monirath Hav, PhD, Anthony Colombo, MS, Elizabeth Chavez, BSc, Cg RT, Tomoko Miyata-Takata, Vivian Lam, Chanel Ghesquiere, Daniel Kos, Talia Goodyear, Allen W. Zhang, Xuehai Wang, PhD, Saeed Saberi, Jiarui W. Ding, Pedro Farinha, MD PhD, Andrew P. Weng, MD PhD, Kerry J Savage, BSc, MD MSc, David W. Scott, MBChB, PhD, Gerald Krystal, PhD, Brad H. Nelson, Anja Mottok, MD PhD, Akil Merchant, MD, Sohrab P Shah, Christian Steidl, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 547.
https://doi.org/10.1182/blood-2019-121584
Published: 2019
Journal Articles

Biomarkers of Overall Survival and Response to Glasdegib and Intensive or Non-Intensive Chemotherapy in Patients with Acute Myeloid Leukemia

Jorge E. Cortes, MD, Akil Merchant, MD, Catriona Jamieson, MD PhD, Daniel A Pollyea, MD, Michael Heuser, MD, Geoffrey Chan, MD, Panpan Wang, Keith A Ching, Jillian Johnson, Thomas O'Brien
Journal: Blood
Blood (2018) 132 (Supplement 1): 2733.
https://doi.org/10.1182/blood-2018-99-111239
Published: 2018