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Journal Articles

First-line consolidation with cemacabtagene ansegedleucel (cema-cel) in patients with large B-cell lymphoma (LBCL) and minimal residual disease (MRD) after response to standard therapy: The pivotal, randomized, open‑label Phase 2 ALPHA3 study

Blood (2025) 146 (Supplement 1): 3730.

https://doi.org/10.1182/blood-2025-3730

Published: 2025

Journal Articles

CD62L enrichment achieves robust expansion and memory phenotype post-infusion in patients with LBCL treated with rondecabtagene autoleucel, an autologous, dual-targeting CD19/CD20 CAR T-cell candidate

Akil Merchant, Ben Harris, Lora Zhao, Sahithi Cheemalamarri, Sobha Potluri, Tahir Latif, Umar Farooq, Sarah Larson

Blood (2025) 146 (Supplement 1): 501.

https://doi.org/10.1182/blood-2025-501

Published: 2025

Journal Articles

Real-world analysis of thromboprophylaxis use during autologous hematopoietic stem cell transplantation for lymphoma and multiple myeloma

Hannah Lee, Haein Kim, Brittany McGalliard, Eyman Sonbol, David Oveisi, Justin Darrah, Robert Vescio, Noah Merin, Akil Merchant, Joshua Sasine, John Chute, Oksana Volod, Ronald Paquette

Blood (2025) 146 (Supplement 1): 3124.

https://doi.org/10.1182/blood-2025-3124

Published: 2025

Journal Articles

Rondecabtagene autoleucel, an autologous, dual-targeting CD19/CD20 CAR T-cell candidate manufactured from CD62L+ enriched T cells, achieves durable responses in patients with large B-cell lymphoma

Sarah Larson, Umar Farooq, Tahir Latif, Felix Mensah, Bradley Hunter, Stefan Ciurea, Nebu Koshy, Locke Bryan, Boyu Hu, William Clark, Hassaan Yasin, Yeonhee Kim, Greg Kaufman, Akil Merchant

Blood (2025) 146 (Supplement 1): 668.

https://doi.org/10.1182/blood-2025-668

Published: 2025

Journal Articles

Cytoplasmic but not nuclear cleaved gsdmd expression in live macrophages and DLBCL cells marks proinflammatory cognate interactions rather than pyroptosis and predicts better patient survival in DLBCL

Blood (2025) 146 (Supplement 1): 7079.

https://doi.org/10.1182/blood-2025-7079

Published: 2025

Journal Articles

Fludarabine and total body irradiation 800 cgy or 1125 cgy for allogeneic stem cell transplant using graft versus host disease prophylaxis with post-transplant cyclophosphamide and tacrolimus, without mycophenolate mofetil (OmitMMF trial)

Ronald Paquette, Haein Kim, Noah Merin, John Chute, Justin Darrah, Hannah Lee, David Oveisi, Joshua Sasine, Robert Vescio, Vinicius Calsavara, Joseph Lownik, Akil Merchant

Blood (2025) 146 (Supplement 1): 4244.

https://doi.org/10.1182/blood-2025-4244

Published: 2025

Journal Articles

Aiming at immune fitness in cancer: Longitudinal functional profiling to predict clinical outcome

Blood (2025) 146 (Supplement 1): 4785.

https://doi.org/10.1182/blood-2025-4785

Published: 2025

Journal Articles

Evaluation and validation of automated multiplexed immunofluorescence for clinical lymphoma diagnoses

Joseph Lownik, Antonio Sorrentino, Anton Villamejor, Akil Merchant

Blood (2025) 146 (Supplement 1): 5343.

https://doi.org/10.1182/blood-2025-5343

Published: 2025

Journal Articles

ALPHA3, a Pivotal Phase 2 Study of First-Line Consolidation with Cemacabtagene Ansegedleucel (Cema-Cel) in Patients with Large B-Cell Lymphoma and Minimal Residual Disease after Response to Standard Therapy

Blood (2024) 144 (Supplement 1): 3132.1.

https://doi.org/10.1182/blood-2024-194909

Published: 2024

Journal Articles

Characterization of the Tumor Microenvironment of Diagnostic Bone Marrow Core Biopsies from African American Multiple Myeloma Patients Using Imaging Mass Cytometry

Anthony Colombo, Esther Lam, Ben Falk, Anton Luis Villamejor, Amie Hwang, Jose Aparicio, Jia Yin Wan, Chun R. Chao, Mallory Bernstein, Ravi Vij, Mark Fiala, Pei Lin, Robert Z. Orlowski, Imran Siddiqi, David Conti, Akil Merchant, Wendy Cozen

Blood (2024) 144 (Supplement 1): 3327.

https://doi.org/10.1182/blood-2024-208818

Published: 2024

Journal Articles

Concurrent Blinatumomab and Human Leukocyte Antigen-Mismatched Cellular Therapy in Patients with High-Risk B-Cell Acute Lymphoblastic Leukemia, a Phase I Prospective Cohort Study

Noah Merin, Haein Kim, Joseph Lownik, Larry Milshteyn, Justin Darrah, Ronald Paquette, Akil Merchant

Blood (2024) 144 (Supplement 1): 4202.

https://doi.org/10.1182/blood-2024-211953

Published: 2024

Journal Articles

Multiplex Analysis of Peripheral Blood in Cancer Patients Predicts Humoral and Cellular Responses to Sars-Cov-2 Vaccines

Blood (2024) 144 (Supplement 1): 3922.

https://doi.org/10.1182/blood-2024-208261

Published: 2024

Journal Articles

Sumoylation As a Novel Target for T-Cell Neoplasms

Larry Milshteyn, Joseph Lownik, Anton Villamejor, Akil Merchant

Blood (2024) 144 (Supplement 1): 6535.

https://doi.org/10.1182/blood-2024-211242

Published: 2024

Journal Articles

First Results of IMPT-314, an Autologous Bispecific CD19/CD20 Chimeric Antigen Receptor (CAR) in Enriched Naive and Central Memory T Cells, for the Treatment of Large B Cell Lymphoma (LBCL)

Sarah M. Larson, Umar Farooq, Boyu Hu, Tahir Latif, Felix A. Mensah, Deepthi Kolli, Giulia Parisi, Greg P. Kaufman, Jonathan E. Benjamin, Akil Merchant

Blood (2024) 144 (Supplement 1): 4824.

https://doi.org/10.1182/blood-2024-200697

Published: 2024

Journal Articles

Comparison of Tacrolimus/Methotrexate and Post-Transplant Cyclophosphamide Graft-Versus Host Disease Prophylaxis for Haploidentical and Matched Allogeneic Stem Cell Transplantation Demonstrates Improved Overall Survival and Reduced Mortality, Shorter Length of Stay, Less Peritransplant Toxicity with Post-Transplant Cyclophosphamide

Noah Merin, Haein Kim, Yuliya Linhares, Akil Merchant, Justin M. Darrah, Joshua Sasine, Hannah Lee, Robert Allen Vescio, David Oveisi, Brittany McGalliard, Ali Rejali, Patricia VanStrien, Ellen B. Klapper, Behrooz Hakimian, John Chute, Ronald Paquette

Blood (2024) 144 (Supplement 1): 2104.

https://doi.org/10.1182/blood-2024-202176

Published: 2024

Journal Articles

Tumor Microenvironment Differences between Diagnostic and Relapsed Classic Hodgkin Lymphoma Revealed By Single Cell Transcriptome Sequencing

Yifan Yin, Tomohiro Aoki, Shinya Rai, Aixiang Jiang, Alexander Xu, Luke O'Brien, Jan Delabie, Lauren Camille Chong, Stacy Hung, Akil Merchant, David W. Scott, Kerry J. Savage, Christian Steidl

Blood (2024) 144 (Supplement 1): 646.

https://doi.org/10.1182/blood-2024-209760

Published: 2024

Journal Articles

NGS MRD Negativity on Day 28 after Brexu Cel in Adults with R/R ALL Is Associated with Favorable Progression Free Survival

Yannis K. Valtis, David Nemirovsky, Sean M. Devlin, Gregory W Roloff, Ibrahim Aldoss, Nikeshan Jeyakumar, Katharine Miller, Amy Zhang, Katherine C. Sutherland, Anjali S. Advani, Marlise R. Luskin, Evan C. Chen, Omer Jamy, Michael R. Grunwald, Ibrahim Muhsen, Noam E. Kopmar, Bhagirathbhai Dholaria, Simone E. Dekker, Jessica T. Leonard, George Yaghmour, Stephanie B. Tsai, Wendy Stock, Jozal Moore, Kristen M. O'Dwyer, Aaron C. Logan, Matthew P Connor, Noelle Frey, Evandro Bezerra, Sumithira Vasu, Kaitlyn C Dykes, Minoo Battiwalla, Chenyu Lin, Matthew Ulrickson, Ran Reshef, Ryan D. Cassaday, Laquisha C. Hill, Catherine J. Lee, Vamsi K. Kota, Jacob Boccucci, Joshua Sasine, Akil Merchant, Vinod Pullarkat, Amelia Langston, Talal Hilal, Rawan Faramand, Melhem M. Solh, Tamer Othman, Timothy E O'Connor, Navneet Majhail, Shabaz Malik, Luke Mountjoy, Rasmus T. Hoeg, Caspian H. Oliai, Vishal Gupta, Divya Koura, Muthu V. Kumaran, Marc Schwartz, Veronika Bachanova, Sean I. Tracy, Maria Odstrcil Bobillo, Abdullah Ladha, Clayton Jackson, Vivian Irrizary Gatell, Olalekan O. Oluwole, Michael Daunov, John Mathews, Paul Shaughnessy, Bijal D Shah, Lori Muffly, Jae H. Park

Blood (2024) 144 (Supplement 1): 4200.

https://doi.org/10.1182/blood-2024-201610

Published: 2024

Journal Articles

Efficacy and Safety of Brexucabtagene Autoleucel for Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia in Patients Aged 60 and Above

Ibrahim Muhsen, Anjali S. Advani, Gregory W Roloff, Nikeshan Jeyakumar, Katharine Miller, Amy Zhang, Katherine C. Sutherland, Michael R. Grunwald, Vamsi K. Kota, Jacob Boccucci, Matthew Ulrickson, Joshua Sasine, Ibrahim Aldoss, Tamer Othman, Sumithira Vasu, Ran Reshef, Marlise R. Luskin, Evan C. Chen, Chenyu Lin, Amelia Langston, Ryan D. Cassaday, Noam E. Kopmar, Stephanie B. Tsai, Timothy E O'Connor, Talal Hilal, Rawan Faramand, Jae H. Park, Yannis K. Valtis, Melhem M. Solh, Evandro Bezerra, Jessica T. Leonard, Simone E. Dekker, Navneet Majhail, Minoo Battiwalla, Shahbaz A. Malik, John Mathews, Paul Shaughnessy, Luke Mountjoy, Rasmus T. Hoeg, Caspian H. Oliai, Vishal Gupta, Divya Koura, Kaitlyn C Dykes, Aaron C. Logan, Muthu V. Kumaran, Wendy Stock, Marc Schwartz, Veronika Bachanova, Sean Tracy, Kristen M. O'Dwyer, Jozal Moore, Catherine J. Lee, Maria Silvina Odstrcil Bobillo, Noelle Frey, Matthew P Connor, Omer Jamy, Michael Daunov, Abdullah Ladha, George Yaghmour, Clayton Jackson, Vivian Irrizary Gatell, Olalekan O. Oluwole, Bhagirathbhai Dholaria, Vinod Pullarkat, Akil Merchant, Bijal D Shah, Lori Muffly, LaQuisa Hill

Blood (2024) 144 (Supplement 1): 523.

https://doi.org/10.1182/blood-2024-210682

Published: 2024

Journal Articles

Development and Characterization of a Novel Murine Peripheral T-Cell Lymphoma Cell Line Which Closely Mimics Human Disease

Larry Milshteyn, Joseph Lownik, Anton Villamejor, Akil Merchant

Blood (2023) 142 (Supplement 1): 3021.

https://doi.org/10.1182/blood-2023-188299

Published: 2023

Journal Articles

Metabolic Reprograming of Exhausted Intratumoral CD8+ T-Cell Underlies Anti-Tumor Activity of Sumoylation Inhibitors in Large B Cell Lymphoma

Joseph Lownik, Larry Milshteyn, Anton Villamejor, Jude Canon, Akil Merchant

Blood (2023) 142 (Supplement 1): 3009.

https://doi.org/10.1182/blood-2023-188238

Published: 2023

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First-line consolidation with cemacabtagene ansegedleucel (cema-cel) in patients with large B-cell lymphoma (LBCL) and minimal residual disease (MRD) after response to standard therapy: The pivotal, randomized, open‑label Phase 2 ALPHA3 study

CD62L enrichment achieves robust expansion and memory phenotype post-infusion in patients with LBCL treated with rondecabtagene autoleucel, an autologous, dual-targeting CD19/CD20 CAR T-cell candidate

Real-world analysis of thromboprophylaxis use during autologous hematopoietic stem cell transplantation for lymphoma and multiple myeloma

Rondecabtagene autoleucel, an autologous, dual-targeting CD19/CD20 CAR T-cell candidate manufactured from CD62L+ enriched T cells, achieves durable responses in patients with large B-cell lymphoma

Cytoplasmic but not nuclear cleaved gsdmd expression in live macrophages and DLBCL cells marks proinflammatory cognate interactions rather than pyroptosis and predicts better patient survival in DLBCL

Fludarabine and total body irradiation 800 cgy or 1125 cgy for allogeneic stem cell transplant using graft versus host disease prophylaxis with post-transplant cyclophosphamide and tacrolimus, without mycophenolate mofetil (OmitMMF trial)

Aiming at immune fitness in cancer: Longitudinal functional profiling to predict clinical outcome

Evaluation and validation of automated multiplexed immunofluorescence for clinical lymphoma diagnoses

ALPHA3, a Pivotal Phase 2 Study of First-Line Consolidation with Cemacabtagene Ansegedleucel (Cema-Cel) in Patients with Large B-Cell Lymphoma and Minimal Residual Disease after Response to Standard Therapy

Characterization of the Tumor Microenvironment of Diagnostic Bone Marrow Core Biopsies from African American Multiple Myeloma Patients Using Imaging Mass Cytometry

Concurrent Blinatumomab and Human Leukocyte Antigen-Mismatched Cellular Therapy in Patients with High-Risk B-Cell Acute Lymphoblastic Leukemia, a Phase I Prospective Cohort Study

Multiplex Analysis of Peripheral Blood in Cancer Patients Predicts Humoral and Cellular Responses to Sars-Cov-2 Vaccines

Sumoylation As a Novel Target for T-Cell Neoplasms

First Results of IMPT-314, an Autologous Bispecific CD19/CD20 Chimeric Antigen Receptor (CAR) in Enriched Naive and Central Memory T Cells, for the Treatment of Large B Cell Lymphoma (LBCL)

Tumor Microenvironment Differences between Diagnostic and Relapsed Classic Hodgkin Lymphoma Revealed By Single Cell Transcriptome Sequencing

NGS MRD Negativity on Day 28 after Brexu Cel in Adults with R/R ALL Is Associated with Favorable Progression Free Survival

Efficacy and Safety of Brexucabtagene Autoleucel for Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia in Patients Aged 60 and Above

Development and Characterization of a Novel Murine Peripheral T-Cell Lymphoma Cell Line Which Closely Mimics Human Disease

Metabolic Reprograming of Exhausted Intratumoral CD8+ T-Cell Underlies Anti-Tumor Activity of Sumoylation Inhibitors in Large B Cell Lymphoma

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