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Journal Articles

CSF2RB Mutations Result in Cytokine-Dependent Gain-of-Function Phenotypes in Classic Hodgkin Lymphoma

Shinya Rai, Tomohiro Aoki, Gerben Duns, Aixiang Jiang, Andrew Lytle, Yifan Yin, Makoto Kishida, Michael Yu Li, Denise Smorra, Cecilia Lee, Katy Milne, Adele Telenius, Luke O'Brien, Katsuyoshi Takata, Tomoko Miyata-Takata, Merrill Boyle, Susana Ben-Neriah, Andrew P. Weng, Andrew Roth, Brad H NelsonH, Laura K. Hilton, Pedro Farinha, Kerry J. Savage, David W. Scott, Christian Steidl
Journal: Blood
Blood (2024) 144 (Supplement 1): 855.
https://doi.org/10.1182/blood-2024-199981
Published: 2024
Journal Articles

Utility of the Central Nervous System International Prognostic Index (CNS-IPI) in Patients with Primary Mediastinal B-Cell Lymphoma Treated with Rituximab-Containing Chemoimmunotherapy

Jiayu Yang, Anna R. Hayden, Diego Villa, Aixiang Jiang, Alina S. Gerrie, Christopher P. Venner, Pedro Farinha, David W. Scott, Laurie H. Sehn, Kerry J. Savage
Journal: Blood
Blood (2024) 144 (Supplement 1): 574.
https://doi.org/10.1182/blood-2024-198794
Published: 2024
Journal Articles

Tumor Microenvironment Differences between Diagnostic and Relapsed Classic Hodgkin Lymphoma Revealed By Single Cell Transcriptome Sequencing

Yifan Yin, Tomohiro Aoki, Shinya Rai, Aixiang Jiang, Alexander Xu, Luke O'Brien, Jan Delabie, Lauren Camille Chong, Stacy Hung, Akil Merchant, David W. Scott, Kerry J. Savage, Christian Steidl
Journal: Blood
Blood (2024) 144 (Supplement 1): 646.
https://doi.org/10.1182/blood-2024-209760
Published: 2024
Journal Articles

CNS Relapse in High-Grade B-cell Lymphoma with MYC and BCL2 Rearrangements and Dark-Zone Signature-Expressing DLBCL

Clinical Trials & Observations
Waleed Alduaij, Aixiang Jiang, Diego Villa, Brett J Collinge, Susana Ben-Neriah, Merrill Boyle, Barbara Meissner, Laura K Hilton, Pedro Farinha, Graham W. Slack, Jeffrey W Craig, Alina S. Gerrie, Ciara L Freeman, Andrew J Mungall, Christian Steidl, Laurie H. Sehn, David W. Scott, Kerry J. Savage
Journal: Blood
Blood blood.2024025725.
https://doi.org/10.1182/blood.2024025725
Published: 2024
Includes: Supplemental data
Journal Articles

Evaluation of a Prognostic 23-Gene Expression Panel in a Set of 390 Multiethnic Hodgkin Lymphoma Patients

Anthony Colombo, Jia Yin Wan, Aixiang Jiang, Jose Aparicio, Esther Lam, Tomohiro Aoki, Joo Y Song, Sheeja Pullarkat, Chun Chao, Juan Manuel Mejia-Arangure, Brenda Hernandez, Pamela B. Allen, Christopher R. Flowers, Sophia S. Wang, Juanita Evans, Owen Chan, Jakub Svoboda, Anja Mottok, Leon Bernal-Mizrachi, Megan Lim, David W. Scott, Imran Siddiqi, David Conti, Christian Steidl, Wendy Cozen
Journal: Blood
Blood (2023) 142 (Supplement 1): 4379.
https://doi.org/10.1182/blood-2023-182906
Published: 2023
Journal Articles

EBV Prevalence and Overall Survival in the M ulti e thnic S tudy of H odgkin Lymphoma (MESH)

Esther Lam, Jia Yin Wan, Jose Aparicio, Sheeja Pullarkat, Anthony Colombo, Joo Y Song, Chun Chao, Juan Manuel Mejia-Arangure, Brenda Hernandez, Aixiang Jiang, Tomohiro Aoki, Pamela B. Allen, Christopher R. Flowers, Sophia S. Wang, Juanita Evans, Owen Chan, Leon Bernal-Mizrachi, David W. Scott, Megan Lim, Jakub Svoboda, Christian Steidl, Anja Mottok, David Conti, Imran Siddiqi, Wendy Cozen
Journal: Blood
Blood (2023) 142 (Supplement 1): 6188.
https://doi.org/10.1182/blood-2023-182919
Published: 2023
Journal Articles

CD79 Expression Is Associated with Cell-of-Origin and Outcome in Diffuse Large B-Cell Lymphoma

Yusuke Naoi, Ryota Chijimatsu, Tomohiro Urata, Kazutaka Sunami, Toshi Imai, Yuichiro Nawa, Yasushi Hiramatsu, Kazuhiko Yamamoto, Soichiro Fujii, Isao Yoshida, Tomofumi Yano, Kazuhiro Ikeuchi, Hiroki Kobayashi, Katsuma Tani, Hiroyuki Murakami, Hideki Ujiie, Yasuharu Sato, Katsuyoshi Takata, Merrill Boyle, Aixiang Jiang, Yoshinobu Maeda, David W. Scott, Daisuke Ennishi
Journal: Blood
Blood (2023) 142 (Supplement 1): 1760.
https://doi.org/10.1182/blood-2023-172972
Published: 2023
Journal Articles

Molecular determinants of clinical outcomes in a real-world diffuse large B-cell lymphoma population

Clinical Trials & Observations
Waleed Alduaij, Brett Collinge, Susana Ben-Neriah, Aixiang Jiang, Laura K. Hilton, Merrill Boyle, Barbara Meissner, Lauren Chong, Tomoko Miyata-Takata, Graham W. Slack, Pedro Farinha, Jeffrey W. Craig, Andrew Lytle, Kerry J. Savage, Diego Villa, Alina S. Gerrie, Ciara L. Freeman, Randy D. Gascoyne, Joseph M. Connors, Ryan D. Morin, Laurie H. Sehn, Andrew J. Mungall, Christian Steidl, David W. Scott
Journal: Blood
Blood (2023) 141 (20): 2493–2507.
https://doi.org/10.1182/blood.2022018248
Published: 2023
Includes: Supplemental data
Journal Articles

Risk of Central Nervous System Involvement in High-Grade B-Cell Lymphoma with MYC and BCL2 Rearrangements: Analysis of a Population-Based Cohort with Routine Fluorescence in Situ Hybridization Testing in British Columbia

Waleed Alduaij, Aixiang Jiang, Diego Villa, Brett Collinge, Susana Ben-Neriah, Merrill Boyle, Barbara Meissner, Laura K Hilton, Pedro Farinha, Graham W Slack, Jeffrey W. Craig, Alina S. Gerrie, Ciara L. Freeman, Andrew J. Mungall, Christian Steidl, Laurie H. Sehn, David W. Scott, Kerry J. Savage
Journal: Blood
Blood (2022) 140 (Supplement 1): 1332–1333.
https://doi.org/10.1182/blood-2022-159356
Published: 2022
Journal Articles

Spatial Tumor Microenvironment Characterization and Outcome of Relapsed/Refractory Classic Hodgkin Lymphoma

Tomohiro Aoki, Aixiang Jiang, Alexander Xu, Alicia Gamboa, Yifan Yin, Katy Milne, Celia Strong, Talia Goodyear, Shaocheng Wu, Lauren C. Chong, Katsuyoshi Takata, Elizabeth Chavez, Tomoko Miyata-Takata, Anthony R. Colombo, Monirath Hav, Adele Telenius, Susana Ben-Neriah, Andrew P. Weng, Kerry J. Savage, David W. Scott, Andrew Roth, Pedro Farinha, Brad H Nelson, Akil Merchant, Christian Steidl
Journal: Blood
Blood (2022) 140 (Supplement 1): 170–171.
https://doi.org/10.1182/blood-2022-158709
Published: 2022
Journal Articles

TRAF3 Loss-of-Function Reveals the Non-Canonical NF-Κb Pathway As a Therapeutic Target in Diffuse Large B-Cell Lymphoma

Michael Y. Li, Lauren C. Chong, Bruce W Woolcock, Adèle Telenius, Susana Ben-Neriah, Graham W Slack, Vivian Lam, Aixiang Jiang, Elena Viganò, Tomohiro Aoki, Shannon Healy, Gerald Krystal, Leandro Venturutti, David W. Scott, Christian Steidl
Journal: Blood
Blood (2022) 140 (Supplement 1): 2042–2043.
https://doi.org/10.1182/blood-2022-159679
Published: 2022
Journal Articles

Clinical Impact of Cell-of-Origin and Double-Hit Signature of DLBCL in Japan

Tomohiro Urata, Kazutaka Sunami, Toshi Imai, Yuichiro Nawa, Yasushi Hiramatsu, Kazuhiko Yamamoto, Soichiro Fujii, Isao Yoshida, Tomofumi Yano, Yusuke Naoi, Kazuhiro Ikeuchi, Hiroki Kobayashi, Katsuma Tani, Shuji Momose, Jun-ichi Tamaru, Merrill Boyle, Aixiang Jiang, Yasuharu Sato, Tadashi Yoshino, Yoshinobu Maeda, David W. Scott, Daisuke Ennishi
Journal: Blood
Blood (2022) 140 (Supplement 1): 6421–6423.
https://doi.org/10.1182/blood-2022-157702
Published: 2022
Journal Articles

Spatial Protein Analysis of the Tumor Microenvironment and Biomarkers in Hodgkin's Lymphoma

Alexander Xu, Tomohiro Aoki, Aixiang Jiang, Alicia Gamboa, Anthony R. Colombo, Christian Steidl, Akil Merchant
Journal: Blood
Blood (2022) 140 (Supplement 1): 3564–3565.
https://doi.org/10.1182/blood-2022-170737
Published: 2022
Journal Articles

A gene expression–based model predicts outcome in children with intermediate-risk classical Hodgkin lymphoma

Clinical Trials & Observations Brief Report
Rebecca L. Johnston, Anja Mottok, Fong Chun Chan, Aixiang Jiang, Arjan Diepstra, Lydia Visser, Adèle Telenius, Randy D. Gascoyne, Debra L. Friedman, Cindy L. Schwartz, Kara M. Kelly, David W. Scott, Terzah M. Horton, Christian Steidl
Journal: Blood
Blood (2022) 139 (6): 889–893.
https://doi.org/10.1182/blood.2021011941
Published: 2022
Includes: Supplemental data
Journal Articles

Population-Wide Introduction of Dose-Adjusted EPOCH-R Is Associated with Improved Outcome of High Grade B-Cell Lymphoma with MYC and BCL2 Rearrangements with Diffuse Large B-Cell Lymphoma Morphology

Waleed Alduaij, Laurie H. Sehn, Aixiang Jiang, Susana Ben-Neriah, Brett Collinge, Laura K Hilton, Merrill Boyle, Barbara Meissner, Pedro Farinha, Graham W. Slack, Jeffrey W Craig, Tomoko Miyata-Takata, Diego Villa, Alina S. Gerrie, Ciara L. Freeman, Kerry J. Savage, Randy D. Gascoyne, Joseph M. Connors, Andrew J. Mungall, Christian Steidl, David W. Scott
Journal: Blood
Blood (2021) 138 (Supplement 1): 1458.
https://doi.org/10.1182/blood-2021-145954
Published: 2021
Journal Articles

Single-Cell Profiling Reveals Clinically Relevant Evolutionary Trajectories and Alternate Biologies in Human Follicular Lymphoma

Xuehai Wang, Michael Nissen, Deanne Gracias, Manabu Kusakabe, Guillermo Simkin, Gerben Duns, Clementine Sarkozy, Elizabeth Chavez, Gabriela Cristina Segat, Jubin Kim, Aixiang Jiang, Tomohiro Aoki, Rashedul Islam, Christina May, Stacy Hung, Kateryna Tyshchenko, Ryan Brinkman, Martin Hirst, Aly Karsan, Ciara L. Freeman, Laurie H. Sehn, Kerry J. Savage, Jeffrey W Craig, David W. Scott, Christian Steidl, Sohrab P Shah, Andrew P. Weng
Journal: Blood
Blood (2021) 138 (Supplement 1): 450.
https://doi.org/10.1182/blood-2021-153237
Published: 2021
Journal Articles

Immune Profiling of Diagnostic DLBCL Biopsies Dramatically Improves upon Cell-of-Origin Risk Stratification

Michael Nissen, Xuehai Wang, Clementine Sarkozy, Aixiang Jiang, Daisuke Ennishi, Tomohiro Aoki, Stacy Hung, Elizabeth Chavez, Jeffrey W Craig, Pedro Farinha, Graham W. Slack, David W. Scott, Christian Steidl, Andrew P. Weng
Journal: Blood
Blood (2021) 138 (Supplement 1): 719.
https://doi.org/10.1182/blood-2021-154082
Published: 2021
Journal Articles

Characterization of DLBCL with a PMBL gene expression signature

Gerben Duns, Elena Viganò, Daisuke Ennishi, Clementine Sarkozy, Stacy S. Hung, Elizabeth Chavez, Katsuyoshi Takata, Christopher Rushton, Aixiang Jiang, Susana Ben-Neriah, Bruce W. Woolcock, Graham W. Slack, Eric D. Hsi, Jeffrey W. Craig, Laura K. Hilton, Sohrab P. Shah, Pedro Farinha, Anja Mottok, Randy D. Gascoyne, Ryan D. Morin, Kerry J. Savage, David W. Scott, Christian Steidl
Journal: Blood
Blood (2021) 138 (2): 136–148.
https://doi.org/10.1182/blood.2020007683
Published: 2021
Includes: Supplemental data
Journal Articles

The impact of MYC and BCL2 structural variants in tumors of DLBCL morphology and mechanisms of false-negative MYC IHC

Brett Collinge, Susana Ben-Neriah, Lauren Chong, Merrill Boyle, Aixiang Jiang, Tomoko Miyata-Takata, Pedro Farinha, Jeffrey W. Craig, Graham W. Slack, Daisuke Ennishi, Anja Mottok, Barbara Meissner, Elizabeth A. Chavez, Alina S. Gerrie, Diego Villa, Ciara Freeman, Kerry J. Savage, Laurie H. Sehn, Ryan D. Morin, Andrew J. Mungall, Randy D. Gascoyne, Marco A. Marra, Joseph M. Connors, Christian Steidl, David W. Scott
Journal: Blood
Blood (2021) 137 (16): 2196–2208.
https://doi.org/10.1182/blood.2020007193
Published: 2021
Includes: Supplemental data
Journal Articles

Mutational landscape of gray zone lymphoma

Clémentine Sarkozy, Stacy S. Hung, Elizabeth A. Chavez, Gerben Duns, Katsuyoshi Takata, Lauren C. Chong, Tomohiro Aoki, Aixiang Jiang, Tomoko Miyata-Takata, Adèle Telenius, Graham W. Slack, Thierry Jo Molina, Susana Ben-Neriah, Pedro Farinha, Peggy Dartigues, Diane Damotte, Anja Mottok, Gilles A. Salles, Rene-Olivier Casasnovas, Kerry J. Savage, Camille Laurent, David W. Scott, Alexandra Traverse-Glehen, Christian Steidl
Journal: Blood
Blood (2021) 137 (13): 1765–1776.
https://doi.org/10.1182/blood.2020007507
Published: 2021
Includes: Supplemental data