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Eric D. Hsi
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Journal Articles

Molecular and Clinical Determinants of CAR-T Therapy Response in DLBCL

Devang Thakkar, Brian T. Hill, Rachel Kositsky, Shari Tian, Leonardo Biral, Veronica Russell, Tushar Dave, Cassandra L. Love, Caroline Roth, Matthew Stuart McKinney, Ahmed Galal, Jadee Neff, Agrima Mian, Ellen Kendall, Sarah L. Ondrejka, Matthew Chiaramonte, Govind Bhagat, Kenneth N. Ofori, Ran Reshef, Alexandra E. Kovach, Tarsheen Sethi, Emily F. Mason, Shakthi Bhaskar, Olalekan O. Oluwole, Chad McCall, Christopher Pallas, Nilanjan Ghosh, Robert Ferdman, George Chen, Francisco Hernandez-Ilizaliturri, Joanna Zurko, Ashley Cunningham, Nirav C Shah, Boyu Hu, Deborah M. Stephens, Monalisa Ghosh, Neil Bailey, Krish Patel, John M. Pagel, Kavya Kannamma Kannan, Eric D. Hsi, Rakhee Vaidya, Andrew Ip, Andre Goy, Swetha Kambhampati, Robert Ohgami, Charalambos Andreadis, Christian A Gordillo, Brianna Just, Jonathon B Cohen, Arielle Baim, Julie Barbello, Erika Cavallone, Veronika Bachanova, Maureen Laschen, Andinet Teferra, Frederique Lorcy, Sylvain Lamure, Guillaume Cartron, Valerie Dardalhon, Kikkeri N Naresh, Magdalena Czader, Anupama Reddy, Elizabeth Thacker, Clayton Parker, Lanie Happ, Sandeep Dave
Journal: Blood
Blood (2024) 144 (Supplement 1): 3409.
https://doi.org/10.1182/blood-2024-199758
Published: 2024
Journal Articles

Neuronal-Glial and Immune Microenvironment Signatures Show Prognostic Effects in Primary CNS Lymphoma

Zijun Y. Xu-Monette, Xiaoxiao Wang, Govind Bhagat, Alexandar Tzankov, Qingyan Au, Carlo Visco, Harry Nunns, Alessandro La Ferlita, Lalit Sehgal, April Chiu, Heounjeong Go, Anamarija M. Perry, Huilan Rao, Mina Xu, Qiongli Zhai, Yafei Wang, Shi Wang, Wenbin Qian, Maurilio Ponzoni, Wen Shuai, Bangchen Wang, Sergio Pina-Oviedo, Luis Carrillo, Kelly Au, Santiago Montes-Moreno, Sr., Karen Dybkaer, Zenggang Pan, William Choi, Michael Møller, Luigi Racioppi, Xiaohui Zhang, Jinming Song, Shanxiang Zhang, Youli Zu, Joo Y. Song, Eric D. Hsi, Fenghuang Zhan, Benjamin M. Parsons, Aliyah R. Sohani, Weina Chen, Fabio Iwamoto, Jeremy S. Abramson, Bing Xu, Yong Li, Ken H. Young
Journal: Blood
Blood (2024) 144 (Supplement 1): 4361.
https://doi.org/10.1182/blood-2024-201598
Published: 2024
Journal Articles

Trial in Progress - Alliance A051901 - Phase I Trial of Methotrexate, Rituximab, Lenalidomide, and Nivolumab (Nivo-MR2) Induction Followed By Lenalidomide and Nivolumab Maintenance in Primary Central Nervous System Lymphoma (PCNSL)

Alvaro J Alencar, Olivia Bobek, Neha Mehta-Shah, Narendranath Epperla, Christine Lu-Emerson, Sarah C. Rutherford, Adam J. Olszewski, Thomas Ollila, Samuel Singer, Travis Dockter, Susan M. Geyer, Lori Rosenstein, Macarena De La Fuente, Eric D. Hsi, Shira N. Dinner, James L. Rubenstein, Nancy L. Bartlett, John P. Leonard
Journal: Blood
Blood (2024) 144 (Supplement 1): 4502.4.
https://doi.org/10.1182/blood-2024-209238
Published: 2024
Journal Articles

Trial in Progress - Alliance A052101: A Randomized Phase 3 Trial of Continuous Vs. Intermittent Maintenance Therapy with Zanubrutinib As Upfront Treatment in Older Patients with Mantle Cell Lymphoma

Anne W Beaven, Susan M. Geyer, Jonathon B. Cohen, Tycel Phillips, Travis Dockter, Priyanka A. Pophali, Gita Thanarajasingam, Gina L. Mazza, Alvaro J Alencar, Shira N. Dinner, Eric D. Hsi, Meng Welliver, Daniel Nikcevich, Brad S. Kahl, Jonathan W. Friedberg, Nancy L. Bartlett, John P. Leonard
Journal: Blood
Blood (2024) 144 (Supplement 1): 1661.3.
https://doi.org/10.1182/blood-2024-207372
Published: 2024
Journal Articles

Randomized study of induction with bendamustine-rituximab ± bortezomib and maintenance with rituximab ± lenalidomide for MCL

Clinical Trials & Observations
Mitchell R. Smith, Opeyemi A. Jegede, Peter Martin, Brian G. Till, Samir S. Parekh, David T. Yang, Eric D. Hsi, Thomas Witzig, Sandeep Dave, David Scott, Curtis Hanson, Lale Kostakoglu Shields, Nizar Abdel-Samad, Carla Casulo, Nancy L. Bartlett, Paolo F. Caimi, Tareq Al Baghdadi, Kristie A. Blum, Mark D. Romer, David J. Inwards, Rachel E. Lerner, Lynne I. Wagner, Richard F. Little, Jonathan W. Friedberg, John P. Leonard, Brad S. Kahl
Journal: Blood
Blood (2024) 144 (10): 1083–1092.
https://doi.org/10.1182/blood.2024023962
Published: 2024
Includes: Supplemental data
Journal Articles

Ibrutinib Added to Standard Conditioning and As Consolidation Therapy Following Autologous Hematopoietic Stem Cell Transplantation (AutoHCT) for Relapsed/Refractory Activated-B-Cell Subtype Diffuse Large B-Cell Lymphoma (ABC-DLBCL): Primary Analysis of the US Intergroup Double-Blind Randomized Phase III Study Alliance A051301/BMT-CTN 1201

Charalambos Andreadis, Olivia Bobek, Eric D. Hsi, Timothy S. Fenske, Susan M. Geyer, Patrick J. Stiff, Brian T. Hill, Mitchell Horwitz, Farhad Khimani, Richard F. Little, Shira N. Dinner, Jonathan W. Friedberg, Brad S. Kahl, Miguel-Angel Perales, Steven M. Devine, John P. Leonard, Nancy L. Bartlett
Journal: Blood
Blood (2023) 142 (Supplement 1): 437.
https://doi.org/10.1182/blood-2023-173742
Published: 2023
Journal Articles

Tumor-Infiltrating Normal B Lymphocytes Have Remarkable Prognostic Effects and Are Crucial for Antitumor Immune Responses in Diffuse Large B-Cell Lymphoma

Zijun Y. Xu-Monette, Yong Li, Thomas Snyder, Tiantian Yu, Tingxun LU, Alexandar Tzankov, Carlo Visco, Govind Bhagat, Wenbin Qian, Karen Dybkaer, April Chiu, Wayne Tam, Youli Zu, Eric D. Hsi, Frederick Hagemeister, Heounjeong Go, Maurilio Ponzoni, Andrés José María Ferreri, Michael Møller, Benjamin M. Parsons, Joannes H.J.M. Van Krieken, Yingjun Wang, Miguel Angel Piris, Jane Winter, Qingyan Au, Ilan Kirsch, Mingzhi Zhang, John D Shaughnessy, Jr, Bing Xu, Ken H. Young
Journal: Blood
Blood (2023) 142 (Supplement 1): 429.
https://doi.org/10.1182/blood-2023-179972
Published: 2023
Journal Articles

Diffuse Large B-Cell Lymphoma Has a Low Frequency of dMMR and High Frequencies of DNA Mismatch Repair Protein High Expression Associated with Lower T-Cell Infiltration

Zijun Y. Xu-Monette, Li Yu, Cancan Luo, Yong Li, Govind Bhagat, Alexandar Tzankov, Carlo Visco, Xiangshan Fan, Xiaosheng Fang, Karen Dybkaer, Ali Sakhdari, April Chiu, Wayne Tam, Youli Zu, Eric D. Hsi, F. B. Hagemeister, Dennis O'Malley, Qingyan Au, Harry Nunns, Heounjeong Go, Maurilio Ponzoni, Andrés José María Ferreri, Michael Møller, Benjamin M. Parsons, Joannes H.J.M. Van Krieken, Miguel Piris, Jane Winter, Bing Xu, Mingzhi Zhang, Ken H. Young
Journal: Blood
Blood (2023) 142 (Supplement 1): 6079.
https://doi.org/10.1182/blood-2023-178366
Published: 2023
Journal Articles

High Ki67 Index Is Associated with Shorter Progression Free Survival in Follicular Lymphoma Patients Treated with Frontline Immunochemotherapy

Jianmin Han, Chad M McCall, Scott Isom, Wesley Smith, Dakota Jenneman, Stephanie Begley, Rupali Bose, Mary Beth Seegars, Eric D. Hsi, Nilanjan Ghosh
Journal: Blood
Blood (2023) 142 (Supplement 1): 4385.
https://doi.org/10.1182/blood-2023-180106
Published: 2023
Journal Articles

Ki-67 Expression of 50% Is the Optimal Cut-Off to Predict Survival Outcomes in Mantle Cell Lymphoma (MCL): A Pooled Analysis from CALGB 50403 (Alliance) and MCL Real-World Study Cohort

Narendranath Epperla, Jeffrey M. Switchenko, Susan M. Geyer, Veronika Bachanova, Stefan K. Barta, Alexey Danilov, Natalie S. Grover, Reem Karmali, Brian T. Hill, Nilanjan Ghosh, Timothy S. Fenske, Peter Martin, Brad S. Kahl, Christopher R. Flowers, Brian K. Link, Eric D. Hsi, Kami J. Maddocks, Kristie A. Blum, Thomas M. Habermann, Matthew J. Maurer, Lawrence David Kaplan, Nancy L. Bartlett, John P. Leonard, Jonathon B. Cohen
Journal: Blood
Blood (2023) 142 (Supplement 1): 380.
https://doi.org/10.1182/blood-2023-189505
Published: 2023
Journal Articles

Unraveling the Transcriptional Landscape of Nodular Lymphocyte-Predominant Hodgkin Lymphoma and T-Cell/Histiocyte Rich Large B-Cell Lymphoma: Impact of Tumor Microenvironment and Checkpoint Gene Expression

Ilja Kalashnikov, Veronica Russell, Panu Kovanen, Johannes Dunkel, Marja-Liisa Karjalainen-Lindsberg, Annika Pasanen, Rachel Kositsky, Sarah L. Ondrejka, Tanu Goyal, Eric D. Hsi, Mette Ølgod Pedersen, Anne Ortved Gang, Magdalena Czader, Jiehao Zhou, Mina Xu, Nathan Paulson, Jean L. Koff, Andrew G Evans, Yasodha Natkunam, Ridas Juskevicius, Abner Louissaint, Elizabeth Thacker, Tushar Dave, Cassandra L. Love, Chad M McCall, Choon Kiat Ong, Michael Churnetski, Haley Martin, Jennifer R. Chapman-Fredricks, Javeed Iqbal, Amy Chadburn, Payal Sojitra, Amir Behdad, William Choi, Jie Xu, Emily F. Ferguson Mason, Kikkeri N Naresh, Yuri D. Fedoriw, Dina Sameh Soliman, Sandeep Dave, Sirpa Leppä
Journal: Blood
Blood (2023) 142 (Supplement 1): 176.
https://doi.org/10.1182/blood-2023-182294
Published: 2023
Journal Articles

Analytical and Clinical Validation of Duoseq, a Novel Assay for Rapid, on-Site Clinical DNA and RNA Sequencing of Hematologic Malignancies

Eric D. Hsi, Magdalena Czader, Brian T. Hill, Elizabeth Thacker, Lin Wang, Christopher Giauque, Andrea Vrydaghs, Matt Sperling, Jordan Bouldin, Robert Erno, Lanie Happ, Clayton Parker, Cassandra L. Love, Jennifer Shingleton, Sandeep Dave
Journal: Blood
Blood (2023) 142 (Supplement 1): 3670.
https://doi.org/10.1182/blood-2023-189030
Published: 2023
Journal Articles

Genomic profiling for clinical decision making in lymphoid neoplasms

Clinical Trials & Observations
Laurence de Leval, Ash A. Alizadeh, P. Leif Bergsagel, Elias Campo, Andrew Davies, Ahmet Dogan, Jude Fitzgibbon, Steven M. Horwitz, Ari M. Melnick, William G. Morice, Ryan D. Morin, Bertrand Nadel, Stefano A. Pileri, Richard Rosenquist, Davide Rossi, Itziar Salaverria, Christian Steidl, Steven P. Treon, Andrew D. Zelenetz, Ranjana H. Advani, Carl E. Allen, Stephen M. Ansell, Wing C. Chan, James R. Cook, Lucy B. Cook, Francesco d’Amore, Stefan Dirnhofer, Martin Dreyling, Kieron Dunleavy, Andrew L. Feldman, Falko Fend, Philippe Gaulard, Paolo Ghia, John G. Gribben, Olivier Hermine, Daniel J. Hodson, Eric D. Hsi, Giorgio Inghirami, Elaine S. Jaffe, Kennosuke Karube, Keisuke Kataoka, Wolfram Klapper, Won Seog Kim, Rebecca L. King, Young H. Ko, Ann S. LaCasce, Georg Lenz, José I. Martin-Subero, Miguel A. Piris, Stefania Pittaluga, Laura Pasqualucci, Leticia Quintanilla-Martinez, Scott J. Rodig, Andreas Rosenwald, Gilles A. Salles, Jesus San-Miguel, Kerry J. Savage, Laurie H. Sehn, Gianpietro Semenzato, Louis M. Staudt, Steven H. Swerdlow, Constantine S. Tam, Judith Trotman, Julie M. Vose, Oliver Weigert, Wyndham H. Wilson, Jane N. Winter, Catherine J. Wu, Pier L. Zinzani, Emanuele Zucca, Adam Bagg, David W. Scott
Journal: Blood
Blood (2022) 140 (21): 2193–2227.
https://doi.org/10.1182/blood.2022015854
Published: 2022
Includes: Supplemental data
Journal Articles

Extranodal Marginal Zone Lymphomas Show Recurrent Mutations in DNA Repair Genes, Cancer-Associated Proliferative Signaling and NOTCH1 Signaling Pathways, Regardless of Anatomic Site

Jennifer R Chapman-Fredricks, Devang Thakkar, Juan Pablo Alderuccio, Kikkeri N Naresh, Sarah L. Ondrejka, Eric D. Hsi, Mina L Xu, Nathan Paulson, Jean L. Koff, David L Jaye, Jonathon B. Cohen, Anne Ortved Gang, Rebecca J Leeman-Neill, Tushar Dave, Lanie Happ, Cassandra Love, Sasan Zandi, Hina Naushad, Emily F Mason, Abner Louissaint, Jr., Haley Martin, Choon Kiat Ong, Raju Pillai, Mette Ø Pedersen, C. Cameron Yin, William Choi, Rex Kwok Him Au-Yeung, Marja-Liisa Karjalainen-Lindsberg, Amy Chadburn, Vincent Sarno, Matthew McKinney, Payal Sojitra, Andrew G Evans, Amir Behdad, Carlos Galvez, Chee Leong Cheng, Magdalena Czader, Jiong Yan, Sandeep S. Dave, Izidore S. Lossos
Journal: Blood
Blood (2022) 140 (Supplement 1): 6378–6380.
https://doi.org/10.1182/blood-2022-165616
Published: 2022
Journal Articles

Mutations of ATM Confer a Risk of Inferior Survival in Patients with TP53- wild Type Mantle Cell Lymphoma

Jean L. Koff, Rachel Kositsky, David L Jaye, Michael C. Churnetski, Katelin Baird, Colin B. O'Leary, Christopher R. Flowers, Sirpa Leppa, Marja-Liisa Karjalainen-Lindsberg, Shaoying Li, Jie Xu, Mette Ø Pedersen, Anne Ortved Gang, Kikkeri N Naresh, Rebecca J Leeman-Neill, Kwok Him Rex Au Yeung, Hina Naushad Qureishi, Javeed Iqbal, Jennifer R Chapman-Fredricks, Chad M. McCall, Michael Crump, Amy Chadburn, Erin C. Mulvey, Izidore S. Lossos, Sandra L. Ondrejka, Eric D. Hsi, Abner Louissaint, Jr., Haley Martin, Eric Tse, Cassandra Love, Tushar Dave, Clay Parker, Choon Kiat Ong, Andrew G Evans, Amir Behdad, Lixin Yang, Nishitha Reddy, Mary Ann Arildsen, Ridas Juskevicius, Jiong Yan, Magdalena Czader, Andrew M. Evens, Dina Sameh Soliman, Yuri Fedoriw, Sandeep S. Dave, Jonathon B. Cohen
Journal: Blood
Blood (2022) 140 (Supplement 1): 3500–3503.
https://doi.org/10.1182/blood-2022-168002
Published: 2022
Journal Articles

Nodular Lymphocyte Predominant Hodgkin Lymphoma with Splenic Involvement Is Characterized By Inflamed Tumor Microenvironment, High Expression of Checkpoint Molecule Gene-Signature and Adverse Outcome

Ilja Kalashnikov, Marja-Liisa Karjalainen-Lindsberg, Panu Kovanen, Johannes Dunkel, Annika Pasanen, Rachel Kositsky, Sarah L. Ondrejka, Eric D. Hsi, Andrew G Evans, Mette Ø Pedersen, Peter H. Norgaard, Anne Ortved Gang, Magdalena Czader, Jiehao Zhou, Mina L Xu, Nathan Paulson, Ridas Juskevicius, Yasodha Natkunam, Abner Louissaint, Jr., Haley Martin, Elizabeth Thacker, Cassandra Love, Shari Tian, Choon Kiat Ong, Chee Leong Cheng, Chad M. McCall, Jean L. Koff, Sheren F. Younes, Mary Ann Arildsen, Jennifer R Chapman-Fredricks, Catalina Amador, Yuri Fedoriw, Carla Casulo, Amy Chadburn, Payal Sojitra, Amir Behdad, Eric Tse, Kikkeri N Naresh, C. Cameron Yin, Rashmi S. Goswami, Sandeep Dave, Sirpa Leppa
Journal: Blood
Blood (2022) 140 (Supplement 1): 3559–3561.
https://doi.org/10.1182/blood-2022-169476
Published: 2022
Journal Articles

Mutations Associated with Progression in Follicular Lymphoma Predict Inferior Outcomes in Newly Diagnosed Patients (Alliance 151303)

David A. Russler-Germain, Kilannin Krysiak, Cody Ramirez, Matthew Mosior, Marcus P. Watkins, Felicia Gomez, Zachary Skidmore, Lee Trani, Feng Gao, Susan M. Geyer, Amanda F. Cashen, Neha Mehta-Shah, Brad S. Kahl, Nancy L. Bartlett, Izidore S. Lossos, Eric D. Hsi, Peter Martin, John P. Leonard, Malachi Griffith, Obi L. Griffith, Todd A. Fehniger
Journal: Blood
Blood (2022) 140 (Supplement 1): 3543–3545.
https://doi.org/10.1182/blood-2022-157051
Published: 2022
Journal Articles

The International Consensus Classification of Mature Lymphoid Neoplasms: a report from the Clinical Advisory Committee

Elias Campo, Elaine S. Jaffe, James R. Cook, Leticia Quintanilla-Martinez, Steven H. Swerdlow, Kenneth C. Anderson, Pierre Brousset, Lorenzo Cerroni, Laurence de Leval, Stefan Dirnhofer, Ahmet Dogan, Andrew L. Feldman, Falko Fend, Jonathan W. Friedberg, Philippe Gaulard, Paolo Ghia, Steven M. Horwitz, Rebecca L. King, Gilles Salles, Jesus San-Miguel, John F. Seymour, Steven P. Treon, Julie M. Vose, Emanuele Zucca, Ranjana Advani, Stephen Ansell, Wing-Yan Au, Carlos Barrionuevo, Leif Bergsagel, Wing C. Chan, Jeffrey I. Cohen, Francesco d’Amore, Andrew Davies, Brunangelo Falini, Irene M. Ghobrial, John R. Goodlad, John G. Gribben, Eric D. Hsi, Brad S. Kahl, Won-Seog Kim, Shaji Kumar, Ann S. LaCasce, Camille Laurent, Georg Lenz, John P. Leonard, Michael P. Link, Armando Lopez-Guillermo, Maria Victoria Mateos, Elizabeth Macintyre, Ari M. Melnick, Franck Morschhauser, Shigeo Nakamura, Marina Narbaitz, Astrid Pavlovsky, Stefano A. Pileri, Miguel Piris, Barbara Pro, Vincent Rajkumar, Steven T. Rosen, Birgitta Sander, Laurie Sehn, Margaret A. Shipp, Sonali M. Smith, Louis M. Staudt, Catherine Thieblemont, Thomas Tousseyn, Wyndham H. Wilson, Tadashi Yoshino, Pier-Luigi Zinzani, Martin Dreyling, David W. Scott, Jane N. Winter, Andrew D. Zelenetz
Journal: Blood
Blood (2022) 140 (11): 1229–1253.
https://doi.org/10.1182/blood.2022015851
Published: 2022
Includes: Supplemental data
Journal Articles

Randomized Phase II/III Study of DA-EPOCH-R +/- Venetoclax in Previously Untreated Double Hit Lymphoma: Initial Results from Alliance A051701

Jeremy S. Abramson, Amy S. Ruppert, Sharmila Giri, Ann Hudson, Eric D. Hsi, Richard F. Little, Steven D. Gore, Anusha Vallurupalli, Daniel J Landsburg, Brad S. Kahl, Jonathan W. Friedberg, Nancy L. Bartlett, John P. Leonard
Journal: Blood
Blood (2021) 138 (Supplement 1): 523.
https://doi.org/10.1182/blood-2021-151266
Published: 2021
Journal Articles

Determining Clinical Course of Diffuse Large B-Cell Lymphoma Using Targeted Transcriptome and Machine Learning Algorithms

Maher Albitar, Hong Zhang, Andre H. Goy, Zijun Xu-Monette, Govind Bhagat, Carlo Visco, Alexandar Tzankov, Xiaosheng Fang, Feng Zhu, Karen Dybkaer, April Chiu, Wayne Tam, Youli Zu, Eric D. Hsi, F. B. Hagemeister, Jooryung Huh, Maurilio Ponzoni, Andrés J M Ferreri, Michael Moller, Benjamin M Parsons, Joannes H.J.M. Van Krieken, Miguel Angel Piris, Jane N. Winter, Yong Li, Bing Xu, Ken H. Young
Journal: Blood
Blood (2021) 138 (Supplement 1): 2395.
https://doi.org/10.1182/blood-2021-148841
Published: 2021