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Deborah M. Stephens
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Journal Articles

LP-168 (Rocbrutinib), a Novel Covalent and Non-Covalent Next-Generation Inhibitor of Bruton's Tyrosine Kinase: Updates on the Phase 1 Trial and Initial Results of the CLL Gatekeeper Mutation Cohort

Jennifer A. Woyach, Danielle M. Brander, Boyu Hu, Kerry A. Rogers, Zulfa Omer, Deborah M. Stephens, Andrea Sitlinger, Fenlai Tan, Yi Chen, Stephen P. Anthony, Yu Chen, Kewei Shang, John C. Byrd
Journal: Blood
Blood (2024) 144 (Supplement 1): 4622.
https://doi.org/10.1182/blood-2024-205775
Published: 2024
Journal Articles

Treatment Outcomes of Patients Treated with Venetoclax-Obinutuzumab Therapy Vs Btki Therapies in 1L CLL: An International Real-World Study

Nicole Lamanna, Jennifer R. Brown, Chaitra S. Ujjani, Toby A. Eyre, Beenish Manzoor, Nilanjan Ghosh, Lindsey Roeker, Matthew S. Davids, Catherine C Coombs, Alan P Skarbnik, Brian T. Hill, Hande H. Tuncer, Lori A. Leslie, Joanna M. Rhodes, Isabelle Fleury, Paul M Barr, Nnadozie Emechebe, Nicolas Martinez-Calle, Christopher E. Jensen, Yun Choi, Dureshahwar Jawaid, Laurie K Pearson, Meghan C. Thompson, Steven E Marx, Wendy J. Sinai, Frederick Lansigan, Bita Fakhri, Deborah M. Stephens, Stephen J. Schuster, Michael Coyle, Irina Pivneva, Talissa Watson, Annie Guerin, Mazyar Shadman
Journal: Blood
Blood (2024) 144 (Supplement 1): 4625.
https://doi.org/10.1182/blood-2024-205223
Published: 2024
Journal Articles

Clinical Outcomes of Transformed Follicular Lymphoma with CAR T-Cell Therapy: A US Multicenter Real-World Analysis

Matthew J. Cortese, MD, MPH, Megan M Herr, Nisha Nair, Jason Romancik, Natalie Grover, Rahul S Bhansali, Colin Thomas, Tamara K Moyo, Vaishalee P Kenkre, Thomas Ollila, Brian Hess, Lindsey Fitzgerald, Geoffrey Shouse, Matthew Matasar, Kaitlin Annunzio, James A Davis, Christy Jesme, Ari Pelcovits, Megan Melody, Jonathan Moreira, Adam Yuh Lin, Shuo Ma, Jane N Winter, Alex Niu, Alexey V. Danilov, Nirav N. Shah, Deborah M. Stephens, Jonathon B. Cohen, Leo I. Gordon, Stefan K. Barta, Narendranath Epperla, Reem Karmali
Journal: Blood
Blood (2024) 144 (Supplement 1): 525.
https://doi.org/10.1182/blood-2024-212106
Published: 2024
Journal Articles

Creation of a Multistate Model to Improve Prognostication across the Disease Course in Advanced Stage Classic Hodgkin Lymphoma (cHL): A Report from the Holistic Consortium

Angie Mae Rodday, Susan K. Parsons, Zhu J Cui, Qingyan Xiang, Nicholas Counsell, Sara Rossetti, Jenica N Upshaw, Annalynn M Williams, Amy A Kirkwood, Hongli Li, James R. Cerhan, Massimo Federico, Jonathan W. Friedberg, Andrea Gallamini, Eliza A. Hawkes, David Hodgson, Martin Hutchings, Peter Johnson, Brian K. Link, Eric Mou, John Radford, Kerry J. Savage, Deborah M. Stephens, Pier Luigi Zinzani, Matthew J. Maurer, Andrew M Evens
Journal: Blood
Blood (2024) 144 (Supplement 1): 567.
https://doi.org/10.1182/blood-2024-207439
Published: 2024
Journal Articles

Real-World Comparison of BCL2 Inhibitor and BTK Inhibitor Therapy in the Front-Line Treatment of CLL Including Patients with Del(17p)/TP53 Mutation

Daniel A. Ermann, Victoria A. Vardell, Allison M. Bock, Joshua J. Horns, Harsh R. Shah, Lindsey Fitzgerald, Boyu Hu, Adam S Kittai, Deborah M. Stephens
Journal: Blood
Blood (2024) 144 (Supplement 1): 1864.
https://doi.org/10.1182/blood-2024-204134
Published: 2024
Journal Articles

Title: Clonal Hematopoiesis and Germline Predisposition in High-Risk Leukemia Pedigrees

Afaf Osman, Julie Feusier, Brian Avery, Deborah M. Stephens, Michael Madsen, Justin Williams, Tony Pomicter, Brandt Jones, Adam Clayton, Philippe Szankasi, Jay Patel, Ramiro Garzon, Nicola J Camp
Journal: Blood
Blood (2024) 144 (Supplement 1): 1296.
https://doi.org/10.1182/blood-2024-198528
Published: 2024
Journal Articles

Patterns of Survival in Patients with Aggressive B-Cell Lymphoma Treated with CD19-Directed Chimeric Antigen Receptor T-Cell Therapy (CART) As Second Versus Later Line of Therapy

Brandon L Ellsworth, Megan Melody, Narendranath Epperla, Natalie Grover, Jason T Romancik, Matthew J Cortese, Rahul S Bhansali, Tamara K Moyo, Vaishalee P Kenkre, Thomas Ollila, Brian Hess, Lindsey Fitzgerald, Geoffrey Shouse, Matthew Matasar, Kaitlin Annunzio, Megan M Herr, James A Davis, Christy Jesme, Ari Pelcovits, Jonathan Moreira, Adam Yuh Lin, Shuo Ma, Jane N Winter, Alexey V. Danilov, Nirav N. Shah, Stefan K. Barta, Jonathon B Cohen, Leo I. Gordon, Deborah M. Stephens, Reem Karmali
Journal: Blood
Blood (2024) 144 (Supplement 1): 612.
https://doi.org/10.1182/blood-2024-202665
Published: 2024
Journal Articles

Feasibility of Discontinuation of Bruton's Tyrosine Kinase Inhibitors in Patients with Chronic Lymphocytic Leukemia: A Patient Survey

Deborah M. Stephens, Chris Stewart, Liza Avruch, Catherine C Coombs, Alexey Danilov, Brian T. Hill, Mazyar Shadman, Alina S. Gerrie, Christopher E. Jensen, Marc Hoffmann, Allison M. Winter, Daniel A. Ermann, Paul M Barr, Susan M. O'Brien, Brian Koffman, John C. Byrd
Journal: Blood
Blood (2024) 144 (Supplement 1): 7743.
https://doi.org/10.1182/blood-2024-193298
Published: 2024
Journal Articles

Association Between Dose Reduction and Duration of Therapy in Patients Receiving Ibrutinib or Acalabrutinib for Chronic Lymphocytic Leukemia: A Medical Chart Review Study

Mazyar Shadman, Lindsey Roeker, Javier Pinilla-Ibarz, Bhavini Srivastava, Sudeep Karve, Gabriel S. Krigsfeld, Erin Franceschini, Chadi Saifan, Siddharth Karanth, Ravi K. Goyal, Julien Rombi, Deborah M. Stephens
Journal: Blood
Blood (2024) 144 (Supplement 1): 3742.
https://doi.org/10.1182/blood-2024-205456
Published: 2024
Journal Articles

Hodgkin Lymphoma Transformation in Patients Who Received No Prior Chemotherapy for CLL/SLL: Outcomes from a Multicenter Retrospective Study in the Modern Era of Therapy

Paul J. Hampel, Ying Huang, Sarah Miller, John N. Allan, Seema A Bhat, David A. Bond, Danielle M. Brander, John C. Byrd, Julio C. Chavez, Elise A. Chong, Alexey Danilov, Matthew S. Davids, Kaitlyn M. Dvorak-Kornaus, Hannah Freedman, Nikita Malakhov, Matthew Matasar, Cecelia Miller, Sameer A. Parikh, Erin M. Parry, Kari G. Rabe, Phil Raess, Manoj Rai, Joanna M. Rhodes, Kerry A. Rogers, Aditi Saha, Jake Schade, Geoffrey Shouse, Stephen E Spurgeon, Deborah M. Stephens, Yucai Wang, Jennifer A. Woyach, Max Yano, Omer Zulfa, Adam S Kittai
Journal: Blood
Blood (2024) 144 (Supplement 1): 5099.
https://doi.org/10.1182/blood-2024-198742
Published: 2024
Journal Articles

Efficacy, Toxicity, and Predictors of Outcomes with CD3-CD20 Bi-Specific Antibodies Post CAR T-Cell Failure for Aggressive B-Cell Lymphoma

Megan Melody, Natalie Grover, Stephanie Franco, Jason T Romancik, Matthew J Cortese, Tamara K Moyo, Rahul S Bhansali, Thomas Ollila, Vaishalee P Kenkre, Lindsey Fitzgerald, Brian Hess, Matthew Matasar, Geoffrey Shouse, Kaitlin Annunzio, Megan M Herr, James A Davis, Christy Jesme, Ari Pelcovits, Jonathan Moreira, Shuo Ma, Jane N Winter, Adam Yuh Lin, Alexey Danilov, Ishan Roy, Stefan K. Barta, Leo I. Gordon, Deborah M. Stephens, Jonathon B Cohen, Narendranath Epperla, Reem Karmali
Journal: Blood
Blood (2024) 144 (Supplement 1): 473.
https://doi.org/10.1182/blood-2024-201626
Published: 2024
Journal Articles

Minimal Residual Disease (MRD)-Adapted Duration of Front-Line Venetoclax and Obinutuzumab Treatment for Fit Patients with Chronic Lymphocytic Leukemia (CLL)

Lindsey Roeker, Anthony R. Mato, Andrew D. Zelenetz, Jae H. Park, Mark Blaine Geyer, Andriy Derkach, David Nemirovsky, Prioty Islam, Lorenzo Falchi, Maria Lia Palomba, Anita Kumar, Gilles Salles, Jennifer Kimberly Lue, Aaron D. Goldberg, Deborah M. Stephens, Victoria Duffy, Gail Panton, Dianna Tyznar, Colleen Dorsey, Dhara Soni, Claire Hutzler, Lauren Nogan, Alexandra Allen, Tenzin Nyima, Thu Quynh Nguyen, Monica Shah, Tamotha R Cook, Jennifer Abillar-Wright, Jamila Brutus, Carissa Laudati, Bejal Kikani, Catherine C Coombs, Michael R. Silvestrone, Christopher E. Jensen, Bita Fakhri, Meghan C. Thompson
Journal: Blood
Blood (2024) 144 (Supplement 1): 1010.
https://doi.org/10.1182/blood-2024-203807
Published: 2024
Journal Articles

Molecular and Clinical Determinants of CAR-T Therapy Response in DLBCL

Devang Thakkar, Brian T. Hill, Rachel Kositsky, Shari Tian, Leonardo Biral, Veronica Russell, Tushar Dave, Cassandra L. Love, Caroline Roth, Matthew Stuart McKinney, Ahmed Galal, Jadee Neff, Agrima Mian, Ellen Kendall, Sarah L. Ondrejka, Matthew Chiaramonte, Govind Bhagat, Kenneth N. Ofori, Ran Reshef, Alexandra E. Kovach, Tarsheen Sethi, Emily F. Mason, Shakthi Bhaskar, Olalekan O. Oluwole, Chad McCall, Christopher Pallas, Nilanjan Ghosh, Robert Ferdman, George Chen, Francisco Hernandez-Ilizaliturri, Joanna Zurko, Ashley Cunningham, Nirav C Shah, Boyu Hu, Deborah M. Stephens, Monalisa Ghosh, Neil Bailey, Krish Patel, John M. Pagel, Kavya Kannamma Kannan, Eric D. Hsi, Rakhee Vaidya, Andrew Ip, Andre Goy, Swetha Kambhampati, Robert Ohgami, Charalambos Andreadis, Christian A Gordillo, Brianna Just, Jonathon B Cohen, Arielle Baim, Julie Barbello, Erika Cavallone, Veronika Bachanova, Maureen Laschen, Andinet Teferra, Frederique Lorcy, Sylvain Lamure, Guillaume Cartron, Valerie Dardalhon, Kikkeri N Naresh, Magdalena Czader, Anupama Reddy, Elizabeth Thacker, Clayton Parker, Lanie Happ, Sandeep Dave
Journal: Blood
Blood (2024) 144 (Supplement 1): 3409.
https://doi.org/10.1182/blood-2024-199758
Published: 2024
Journal Articles

A Multi-Center Retrospective Study on Complex Karyotype in Patients with Richter Transformation Who Received No Chemoimmunotherapy for Their CLL

Cecelia Miller, Ying Huang, John N. Allan, Seema A. Bhat, David A. Bond, Danielle M. Brander, John C. Byrd, Julio C. Chavez, Elise A. Chong, Alexey Danilov, Mark R Dowling, Kaitlyn M. Dvorak-Kornaus, Paul J. Hampel, Carrie I Ho, Prioty Islam, Nikita Malakhov, Matthew Matasar, Sarah Miller, Sameer A. Parikh, Kari G. Rabe, Joanna M. Rhodes, Lindsey Roeker, Kerry A. Rogers, Aditi Saha, Alan P Skarbnik, Hamish W Scott, Jake Schade, Mazyar Shadman, Geoffrey Shouse, Deborah M. Stephens, Meghan C. Thompson, Philip A. Thompson, Yucai Wang, Jennifer A. Woyach, Max Yano, Zulfa Omer, Adam S Kittai
Journal: Blood
Blood (2024) 144 (Supplement 1): 3245.
https://doi.org/10.1182/blood-2024-205668
Published: 2024
Journal Articles

Follow-up from the A041202 study shows continued efficacy of ibrutinib regimens for older adults with CLL

CME Clinical Trials & Observations
Jennifer A. Woyach, Gabriela Perez Burbano, Amy S. Ruppert, Cecelia Miller, Nyla A. Heerema, Weiqiang Zhao, Anna Wall, Wei Ding, Nancy L. Bartlett, Danielle M. Brander, Paul M. Barr, Kerry A. Rogers, Sameer A. Parikh, Deborah M. Stephens, Jennifer R. Brown, Gerard Lozanski, James Blachly, Sreenivasa Nattam, Richard A. Larson, Harry Erba, Mark Litzow, Selina Luger, Carolyn Owen, Charles Kuzma, Jeremy S. Abramson, Richard F. Little, Shira Dinner, Richard M. Stone, Geoffrey Uy, Wendy Stock, Sumithra J. Mandrekar, John C. Byrd
Journal: Blood
Blood (2024) 143 (16): 1616–1627.
https://doi.org/10.1182/blood.2023021959
Published: 2024
Includes: Supplemental data
Journal Articles

Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy for Richter's Transformation: An International Multicenter Retrospective Study

Adam S Kittai, David A. Bond, Ying Huang, Seema A Bhat, Emily Blyth, John C. Byrd, Julio C Chavez, Matthew S Davids, Jamie P Dela Cruz, Mark R Dowling, Caitlyn Duffy, Carrie I Ho, Caron A Jacobson, Samantha M. Jaglowski, Nitin Jain, Kevin H Lin, Christine McCarthy, Erin M Parry, Manoj Rai, Kerry A Rogers, Aditi Saha, Levanto Schachter, Hamish Scott, Jayastu Senapati, Mazyar Shadman, Tanya Siddiqi, Deborah M. Stephens, Vinay Vanguru, William G. Wierda, Omer Zulfa, Jennifer A. Woyach, Philip A. Thompson
Journal: Blood
Blood (2023) 142 (Supplement 1): 108.
https://doi.org/10.1182/blood-2023-180858
Published: 2023
Journal Articles

Single-Cell Long-Read Sequencing Enables the Dissection of BTK Subclonal Dynamics in CLL Treatment

Gage Black, Xiaomeng Huang, Yi Qiao, Philip Moos, Deborah M. Stephens, Gabor Marth, Jennifer A. Woyach
Journal: Blood
Blood (2023) 142 (Supplement 1): 1893.
https://doi.org/10.1182/blood-2023-179425
Published: 2023
Journal Articles

Trends in Survival Outcomes for Mantle Cell Lymphoma in the Era of Novel Therapies

Daniel A. Ermann, Victoria A. Vardell, Lindsey Fitzgerald, Harsh Shah, Allison M. Bock, Deborah M. Stephens, Boyu Hu
Journal: Blood
Blood (2023) 142 (Supplement 1): 1669.
https://doi.org/10.1182/blood-2023-190383
Published: 2023
Journal Articles

Improved Survival of R/R Double Hit/Triple Hit Lymphoma in the Era of CD19 Chimeric Antigen T Cell (CART) Therapy

Sanjal H. Desai, Nuttavut Sumransub, Rich Evans, Marcus P Watkins, Reem Karmali, Gaurav Goyal, Mitchell E. Hughes, Arushi Khurana, Francisco J. Hernandez-Ilizaliturri, Joanna Zurko, Ayesha Hassan, Haris Hatic, Imran A. Nizamuddin, Andrew M Evens, Andrea Carolina Anampa-Guzmán, Yi Lin, Iris Isufi, Mehdi Hamadani, Saurabh A Rajguru, Naveena Lall, Aung M. Tun, Brian T. Hill, Deborah M. Stephens, Paolo F. Caimi, Daniel A. Ermann, Brad S. Kahl, Daniel J. Landsburg, Grzegorz S. Nowakowski
Journal: Blood
Blood (2023) 142 (Supplement 1): 308.
https://doi.org/10.1182/blood-2023-183001
Published: 2023
Journal Articles

Lisocabtagene Maraleucel (liso-cel) in R/R CLL/SLL: 24-Month Median Follow-up of TRANSCEND CLL 004

Tanya Siddiqi, David G Maloney, Saad S. Kenderian, Danielle M Brander, Kathleen Dorritie, Jacob Soumerai, Peter A Riedell, Nirav N. Shah, Rajneesh Nath, Bita Fakhri, Deborah M. Stephens, Shuo Ma, Tatyana Feldman, Scott R. Solomon, Stephen J. Schuster, Serena K. Perna, Sherilyn A. Tuazon, San-San Ou, Neha Rane, William G. Wierda
Journal: Blood
Blood (2023) 142 (Supplement 1): 330.
https://doi.org/10.1182/blood-2023-179529
Published: 2023