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Ash A. Alizadeh
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Journal Articles

Prognostic Utility of Minimal Residual Disease (MRD) after Curative Intent Induction Therapy for DLBCL: A Prospective Real-World Ctdna Study

Brian J. Sworder, Sang Eun Yoon, Seok Jin Kim, Andre Schultz, Gregory Hogan, Sandra Close, Jacob J. Chabon, Maximilian Diehn, David M. Kurtz, Ash A. Alizadeh, Won Seog Kim
Journal: Blood
Blood (2023) 142 (Supplement 1): 69.
https://doi.org/10.1182/blood-2023-187650
Published: 2023
Journal Articles

Genomic, Transcriptional, and Immunological Validation of Distinct Molecular Subtypes of Classic Hodgkin Lymphoma through Tissue-Based and Noninvasive Methods

Stefan K. Alig, Mohammad Shahrokh Esfahani, Andrea Garofalo, Michael Yu Li, Cédric Rossi, Timothy Flerlage, Jamie E. Flerlage, Ragini Adams, Michael S. Binkley, Navika Shukla, Michael Jin, Mari Olsen, Adele Telenius, Jurik A Mutter, Joseph Schroers-Martin, Brian J. Sworder, Shinya Rai, Daniel King, Andre Schultz, Jan Lukas Bögeholz, Shengqin Su, Karan R Kathuria, Chih Long Liu, Xiaoman Kang, Deanna M. Langfitt, Kristine Faye Pobre-Piza, Feng Tian, Maya J. Strohband, Valeria Spina, Thomas Tousseyn, Lieselot Buedts, Luc-Matthieu Fornecker, Sharon M. Castellino, Ranjana H. Advani, Davide Rossi, Ryan C Lynch, Herve Ghesquieres, Olivier Casasnovas, David M. Kurtz, Lianna J. Marks, Michael P. Link, Marc Andre, Peter Vandenberghe, Christian Steidl, Maximilian Diehn, Ash A. Alizadeh
Journal: Blood
Blood (2023) 142 (Supplement 1): 177.
https://doi.org/10.1182/blood-2023-186810
Published: 2023
Journal Articles

Inferred Gene Expression By Cell-Free DNA Profiling Allows Noninvasive Lymphoma Classification

Jurik A Mutter, Mohammad Shahrokh Esfahani, Joseph Schroers-Martin, Stefan K. Alig, Mark P. Hamilton, Brian J. Sworder, Benoit Tessoulin, Jan Boegeholz, Timothy Flerlage, Jamie E. Flerlage, Michael S. Binkley, Takeshi Sugio, Cédric Rossi, Mari Olsen, Chih Long Liu, Steven Le Gouill, David M. Kurtz, Maximilian Diehn, Ash A. Alizadeh
Journal: Blood
Blood (2023) 142 (Supplement 1): 245.
https://doi.org/10.1182/blood-2023-186853
Published: 2023
Journal Articles

CAR19 Therapy Drives Expansion of Clonal Hematopoiesis and Associated Cytopenias

Mark P. Hamilton, Brian J. Sworder, Stefan K. Alig, Zinaida Good, Jan Boegeholz, Joseph Schroers-Martin, John Tamaresis, Mohammad Shahrokh Esfahani, Ying Lu, Mari Olsen, Chih Long Liu, Zachary Ehlinger, Moksha Desai, Felicia Liu-Fei, Lori S. Muffly, Robert S. Negrin, Sally Arai, Laura Johnston, Robert Lowsky, Everett H. Meyer, Andrew R. Rezvani, Judith Shizuru, Wen-Kai Weng, Parveen Shiraz, Surbhi Sidana, Sushma Bharadwaj, Melody Smith, Saurabh Dahiya, Bita Sahaf, Maximilian Diehn, Matthew J. Frank, Crystal L. Mackall, David M. Kurtz, David B. Miklos, Ash A. Alizadeh
Journal: Blood
Blood (2023) 142 (Supplement 1): 360.
https://doi.org/10.1182/blood-2023-182522
Published: 2023
Journal Articles

End-of-Treatment Response Assessment after Frontline Therapy for Aggressive B-Cell Lymphoma: Landmark Comparison of a Singular PET/CT Scan Versus Ultrasensitive Circulating Tumor DNA

Mark Roschewski, Liza Lindenberg, Esther Mena, Rahul Lakhotia, Christopher Melani, Seth M. Steinberg, Andre Schultz, Gregory Hogan, Jake J. Chabon, Sandra Close, Maximilian Diehn, Brian J. Sworder, David M. Kurtz, Ash A. Alizadeh, Wyndham H. Wilson
Journal: Blood
Blood (2023) 142 (Supplement 1): 192.
https://doi.org/10.1182/blood-2023-180007
Published: 2023
Journal Articles

Durable Remissions in Advanced Stage and Molecularly High Risk Untreated Classic Hodgkin Lymphoma with Pembrolizumab + AVD

Ryan C Lynch, Stefan K. Alig, Chaitra S Ujjani, Christina Poh, Edus H Warren, Stephen D Smith, Mazyar Shadman, Brian G Till, Vikram Raghunathan, Yolanda D Tseng, Susan Ottemiller, Bonnie Joy, Melissa Mary Fessel, Hongyan Du, Jacquelin Vandermeer, Alyssa Kelly, Heather Rasmussen, Jenna M Voutsinas, Qian Wu, Ash A. Alizadeh, Ajay K Gopal
Journal: Blood
Blood (2023) 142 (Supplement 1): 4429.
https://doi.org/10.1182/blood-2023-179547
Published: 2023
Journal Articles

Distinct Circulating Genomic Features of Classical Hodgkin Lymphoma of Older Adults

Cédric Rossi, Jan Boegeholz, Stefan K. Alig, Andrea Garofalo, Mohammad Shahrokh Esfahani, Joseph Schroers-Martin, Mari Olsen, Xiaoman Kang, David M. Kurtz, Takeshi Sugio, Mark P. Hamilton, Marc Andre, Rene-Olivier Casasnovas, Luc Matthieu Fornecker, Maximilian Diehn, Herve Ghesquieres, Ash A. Alizadeh
Journal: Blood
Blood (2023) 142 (Supplement 1): 4369.
https://doi.org/10.1182/blood-2023-178257
Published: 2023
Journal Articles

Phased Variants Allow Robust Profiling of Circulating Tumor DNA in Untreated Follicular Lymphomas

Ákos Nagy, Bence Bátai, Gregory Hogan, Jacob J. Chabon, Mikayla Troke, Lance Riley, Andre Schultz, Sandra Close, Maximilian Diehn, Donát Alpár, Botond Timár, Ash A. Alizadeh, David M. Kurtz, Csaba Bödör
Journal: Blood
Blood (2023) 142 (Supplement 1): 1626.
https://doi.org/10.1182/blood-2023-189824
Published: 2023
Journal Articles

An Integrated Multimodal Framework for Noninvasive TCL Disease Detection and Monitoring

Takeshi Sugio, Navika Shukla, Michael S Khodadoust, Monica Nesselbush, Koji Kato, Stefan K. Alig, Jan Boegeholz, Joseph Schroers-Martin, Mohammad Shahrokh Esfahani, Jurik A. Mutter, Andrea Garofalo, Soyeong Jun, Mark P. Hamilton, Cédric Rossi, Mari Olsen, Chih Long Liu, Koichi Akashi, Maximilian Diehn, Ash A. Alizadeh
Journal: Blood
Blood (2023) 142 (Supplement 1): 1620.
https://doi.org/10.1182/blood-2023-180492
Published: 2023
Journal Articles

Investigating the Cell States and Prognostic Impact of Tumor Microenvironment Ecosystems in Classic Hodgkin Lymphoma

Shengqin Su, Ajay Subramanian, Timothy Flerlage, Jamie E. Flerlage, Stefan K. Alig, Everett J. Moding, Richard T. Hoppe, Ranjana H. Advani, Yasodha Natkunam, Ash A. Alizadeh, Michael S. Binkley
Journal: Blood
Blood (2023) 142 (Supplement 1): 3016.
https://doi.org/10.1182/blood-2023-180288
Published: 2023
Journal Articles

Early and Sustained Circulating Tumor DNA Response Dynamics after Loncastuximab Tesirine for Relapsed/Refractory Diffuse Large B-Cell Lymphoma

David M. Kurtz, Gregory Hogan, Andre Schultz, Jacob J. Chabon, Ash A. Alizadeh, Karin Havenith, Sara Samari, Tim Kopotsha, Luqiang Wang, Yajuan Qin, Ying Wang, Serafino Pantano
Journal: Blood
Blood (2023) 142 (Supplement 1): 3133.
https://doi.org/10.1182/blood-2023-179977
Published: 2023
Journal Articles

Optimizing Circulating Tumor DNA Limits of Detection for DLBCL during First Line Therapy

Jordan Goldstein, Won Seog Kim, Sang Eun Yoon, Seok Jin Kim, Mark Roschewski, Jason Westin, Ryan C Lynch, Stefan K. Alig, Sandra Close, Jacob J. Chabon, Davide Rossi, Wyndham H Wilson, Maximilian Diehn, Ash A. Alizadeh, David M. Kurtz
Journal: Blood
Blood (2023) 142 (Supplement 1): 187.
https://doi.org/10.1182/blood-2023-187759
Published: 2023
Journal Articles

Circulating Tumor DNA Dynamics as Early Outcome Predictors for Lisocabtagene Maraleucel as Second-Line Therapy for Large B-Cell Lymphoma from the Phase 3 TRANSFORM Study

Lara Stepan, Sahar Ansari, Abood Okal, Justine Dell'Aringa, Ethan Thompson, Alessandro Crotta, Victor A Chow, Jeremy S. Abramson, Manali Kamdar, Jacob J. Chabon, Gregory Hogan, David M. Kurtz, Ash A. Alizadeh, Leanne Peiser
Journal: Blood
Blood (2023) 142 (Supplement 1): 225.
https://doi.org/10.1182/blood-2023-181007
Published: 2023
Journal Articles

Longitudinal Noninvasive Surveillance & Fragmentomic Characterization of Follicular Lymphoma

Joseph Schroers-Martin, Jurik A Mutter, Mohammad Shahrokh Esfahani, Florian Scherer, Joanne Soo, Stefan K. Alig, David M. Kurtz, Takeshi Sugio, Cédric Rossi, Benoit Tessoulin, Mari Olsen, Chih Long Liu, Maximilian Diehn, Ash A. Alizadeh
Journal: Blood
Blood (2023) 142 (Supplement 1): 528.
https://doi.org/10.1182/blood-2023-187116
Published: 2023
Journal Articles

Concurrent pembrolizumab with AVD for untreated classic Hodgkin lymphoma

Clinical Trials & Observations
Ryan C. Lynch, Chaitra S. Ujjani, Christina Poh, Edus H. Warren, Stephen D. Smith, Mazyar Shadman, Brian Till, Vikram M. Raghunathan, Stefan Alig, Ash A. Alizadeh, Avanti Gulhane, Delphine L. Chen, Yolanda Tseng, Hilary Coye, Megan Shelby, Susan Ottemiller, Sarith Keo, Kaitlin Verni, Hongyan Du, Jacquelin Vandermeer, Ashley Gaston, Heather Rasmussen, Paul Martin, Edmond Marzbani, Jenna Voutsinas, Ajay K. Gopal
Journal: Blood
Blood (2023) 141 (21): 2576–2586.
https://doi.org/10.1182/blood.2022019254
Published: 2023
Includes: Supplemental data
Journal Articles

Genomic profiling for clinical decision making in lymphoid neoplasms

Clinical Trials & Observations
Laurence de Leval, Ash A. Alizadeh, P. Leif Bergsagel, Elias Campo, Andrew Davies, Ahmet Dogan, Jude Fitzgibbon, Steven M. Horwitz, Ari M. Melnick, William G. Morice, Ryan D. Morin, Bertrand Nadel, Stefano A. Pileri, Richard Rosenquist, Davide Rossi, Itziar Salaverria, Christian Steidl, Steven P. Treon, Andrew D. Zelenetz, Ranjana H. Advani, Carl E. Allen, Stephen M. Ansell, Wing C. Chan, James R. Cook, Lucy B. Cook, Francesco d’Amore, Stefan Dirnhofer, Martin Dreyling, Kieron Dunleavy, Andrew L. Feldman, Falko Fend, Philippe Gaulard, Paolo Ghia, John G. Gribben, Olivier Hermine, Daniel J. Hodson, Eric D. Hsi, Giorgio Inghirami, Elaine S. Jaffe, Kennosuke Karube, Keisuke Kataoka, Wolfram Klapper, Won Seog Kim, Rebecca L. King, Young H. Ko, Ann S. LaCasce, Georg Lenz, José I. Martin-Subero, Miguel A. Piris, Stefania Pittaluga, Laura Pasqualucci, Leticia Quintanilla-Martinez, Scott J. Rodig, Andreas Rosenwald, Gilles A. Salles, Jesus San-Miguel, Kerry J. Savage, Laurie H. Sehn, Gianpietro Semenzato, Louis M. Staudt, Steven H. Swerdlow, Constantine S. Tam, Judith Trotman, Julie M. Vose, Oliver Weigert, Wyndham H. Wilson, Jane N. Winter, Catherine J. Wu, Pier L. Zinzani, Emanuele Zucca, Adam Bagg, David W. Scott
Journal: Blood
Blood (2022) 140 (21): 2193–2227.
https://doi.org/10.1182/blood.2022015854
Published: 2022
Includes: Supplemental data
Journal Articles

Ultrasensitive Circulating Tumor DNA (ctDNA) Dynamics after Autologous CD30.CAR-T Cell Therapy for Relapsed or Refractory (r/r) Classical Hodgkin Lymphoma (CHARIOT Trial)

David M. Kurtz, Sairah Ahmed, Cheuk Ka Tong, Matthew Mei, Cliff Ding, Ian W. Flinn, Peter A. Riedell, Gregory J. Hogan, Andre Schultz, Jacob J. Chabon, Helen E. Heslop, Aung Myo, Ash A. Alizadeh, Ivan D. Horak
Journal: Blood
Blood (2022) 140 (Supplement 1): 2378–2380.
https://doi.org/10.1182/blood-2022-162150
Published: 2022
Journal Articles

Ultrasensitive MRD Profiling Predicts Outcomes in DLBCL after Frontline Therapy with Tafasitamab in Combination with Lenalidomide and R-CHOP

David M. Kurtz, Gregory J. Hogan, Andre Schultz, Katerina Kopeckova, Christian Kuffer, Derek Blair, Steve Wagner, Sandra Close, Maximilian Diehn, Jacob J. Chabon, Ash A. Alizadeh, Jason Westin
Journal: Blood
Blood (2022) 140 (Supplement 1): 3498–3499.
https://doi.org/10.1182/blood-2022-168378
Published: 2022
Journal Articles

Accurate Detection of Clinically Actionable Copy Number Variants in Diverse Hematological Neoplasms By Routine Targeted Sequencing: A Comparative Performance Study

Alicia Palomino Mosquera, Hitomi Hosoya, Michael C. Jin, Mohammad Shahrokh Esfahani, Joseph Schroers-Martin, Brian Sworder, Chih Long Liu, Elizabeth Spiteri, Yasodha Natkunam, James L Zehnder, Henning Stehr, David M. Kurtz, Ash A. Alizadeh
Journal: Blood
Blood (2022) 140 (Supplement 1): 10712–10713.
https://doi.org/10.1182/blood-2022-167900
Published: 2022
Journal Articles

Viral cfDNA Profiling Reveals Distinct EBV Subtypes and Stratifies Risk in Hodgkin Lymphomas

Andrea Garofalo, Stefan K. Alig, Joseph Schroers-Martin, Ragini Malika Shyam, Mari Olsen, David M. Kurtz, Cédric Rossi, Andre Schultz, Karan R. Kathuria, Chih Long Liu, Valeria Spina, Jamie E. Flerlage, Sharon M. Castellino, Ranjana H. Advani, Davide Rossi, Ryan C. Lynch, Olivier Casasnovas, Lianna J. Marks, Michael P. Link, Marc Andre, Peter Vandenberghe, Christian Steidl, Maximilian Diehn, Ash A. Alizadeh
Journal: Blood
Blood (2022) 140 (Supplement 1): 1318–1319.
https://doi.org/10.1182/blood-2022-159230
Published: 2022