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Stefan K. Alig
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Journal Articles

Ultrasensitive Circulating Tumor DNA MRD Status Predicts Treatment Failure & Complements PET/CT throughout Treatment for Early and Advanced Stage Classic Hodgkin Lymphoma

Jan Boegeholz, Cedric Rossi, Jordan S Goldstein, Stefan K. Alig, Andrea Garofalo, Mohammad Shahrokh Esfahani, Joseph G. Schroers-Martin, Chih Long Liu, Mari Olsen, Xiaoman Kang, Feng Tian, David Kurtz, Marc Andre, Luc-Matthieu Fornecker, Olivier Casasnovas, Maximilian Diehn, Herve Ghesquieres, Ash A. Alizadeh
Journal: Blood
Blood (2024) 144 (Supplement 1): 565.
https://doi.org/10.1182/blood-2024-201877
Published: 2024
Journal Articles

Baseline Prognostic Factors Do Not Predict End of Treatment Ctdna MRD Status and Have Limited Impact on MRD Prognostic Performance in DLBCL

Jordan S Goldstein, Mark Roschewski, Won-Seog Kim, Sang Eun Yoon, Seok Jin Kim, Jason R. Westin, Ryan C Lynch, Stefan K. Alig, Sandra Close, Jacob Chabon, Davide Rossi, Wyndham H. Wilson, David Kurtz, Ash A. Alizadeh
Journal: Blood
Blood (2024) 144 (Supplement 1): 651.
https://doi.org/10.1182/blood-2024-211068
Published: 2024
Journal Articles

Modulation of the Tumor Microenvironment By CCL19 in Primary CNS Lymphomas

Julia C. Kuehn, Roman Sankowski, Nicolas N. Neidert, Elena Grabis, Jurik A. Mutter, Stefan K. Alig, Junyi Zhang, Christian Klingler, Lavanya Ranganathan, Fabian Hummel, Sabine Bleul, Eliza M. Lauer, Dieter Henrik Heiland, Marco Prinz, Katharina J. Müller, Louisa von Baumgarten, Justus Duyster, Elisabeth Schorb, Maximilian Diehn, Ash A. Alizadeh, Peter C. Reinacher, Florian Scherer
Journal: Blood
Blood (2024) 144 (Supplement 1): 856.
https://doi.org/10.1182/blood-2024-199257
Published: 2024
Journal Articles

High Rates of Undetectable MRD By Phased-Seq on Interim and End of Treatment Timepoints in Untreated Advanced Stage Chl Treated with Pembrolizumab + AVD

Ryan C Lynch, Stefan K. Alig, Chaitra S. Ujjani, Christina Poh, Edus H. Warren, Stephen D. Smith, Mazyar Shadman, Brian G. Till, Vikram Raghunathan, Yolanda D Tseng, Susan Ottemiller, Bonnie Joy, Melissa Mary Fessel, Hongyan Du, Jacquelin Vandermeer, Alyssa Kelly, Heather Rasmussen, Jenna M. Voutsinas, Ash A. Alizadeh, Ajay K. Gopal
Journal: Blood
Blood (2024) 144 (Supplement 1): 3051.
https://doi.org/10.1182/blood-2024-206512
Published: 2024
Journal Articles

The Effect of Ibrutinib on the Myeloid Cell Compartment in Central Nervous System Lymphoma Slice Cultures

Julia C. Kuehn, Nicolas N. Neidert, Junyi Zhang, Jurik A Mutter, Stefan K. Alig, Christian Klingler, Fabian Hummel, Sabine Bleul, Lavanya Ranganathan, Jürgen Beck, Marco Prinz, Maximilian Diehn, Ash A. Alizadeh, Justus Duyster, Roman Sankowski, Dieter Henrik Heiland, Florian Scherer
Journal: Blood
Blood (2024) 144 (Supplement 1): 4374.
https://doi.org/10.1182/blood-2024-199125
Published: 2024
Journal Articles

Guiding Treatment and Clinical Management of Patients with CNS Lymphomas By Minimal-Invasive Detection of Circulating Tumor DNA in Cerebrospinal Fluid

Samuel Weinschenk, Ulrike Philipp, Julia C. Kuehn, Katharina J. Müller, Josia Fauser, David Böckle, Inga Gebhard, Marta Hinz, Nicolas N. Neidert, Sabine Bleul, Eliza M. Lauer, Jurik A. Mutter, Stefan K. Alig, David Kurtz, Jürgen Finke, Reinhard Marks, Maximilian Diehn, Ash A. Alizadeh, Peter C. Reinacher, Julius Wehrle, Dominik Wolf, Florian Kocher, Björn Chapuy, Jürgen Beck, Marco Prinz, Louisa von Baumgarten, Elisabeth Schorb, Justus Duyster, Florian Scherer
Journal: Blood
Blood (2024) 144 (Supplement 1): 1583.
https://doi.org/10.1182/blood-2024-202943
Published: 2024
Journal Articles

Integrating Genomic & Transcriptomic Features for Noninvasive Detection, Characterization, and Monitoring of T-Cell Lymphomas

Takeshi Sugio, Monica Nesselbush, Navika Shukla, Andrea Garofalo, Jurik A. Mutter, Mohammad Shahrokh Esfahani, Stefan K. Alig, Shuyu Shi, Troy Noordenbos, Mark P. Hamilton, Cedric Rossi, Feng Tian, Chih Long Liu, Mari Olsen, Xiaoman Kang, David A Russler-Germain, Steven Horwitz, Koji Kato, Ayumu Ito, Makoto Yamagishi, Takahiro Fukuda, Koichi Akashi, Kaoru Uchimaru, Michael S. Khodadoust, Maximilian Diehn, Neha Mehta-Shah, Ash A. Alizadeh
Journal: Blood
Blood (2024) 144 (Supplement 1): 454.
https://doi.org/10.1182/blood-2024-206518
Published: 2024
Journal Articles

Distinct Molecular Aberrations of Classic Hodgkin Lymphoma in Older Adults Identified By Comprehensive Genomic Profiling

Cedric Rossi, Jan Boegeholz, Jordan S Goldstein, Shuyu Shi, Shengqin Su, Benoit Tessoulin, Stefan K. Alig, Andrea Garofalo, Mohammad Shahrokh Esfahani, Joseph G. Schroers-Martin, Chih Long Liu, Mari Olsen, Xiaoman Kang, Feng Tian, David Kurtz, Takeshi Sugio, Troy Noordenbos, Marc Andre, Luc-Matthieu Fornecker, Edith Julia, Alexandra Traverse-Glehen, Olivier Casasnovas, Michael S. Binkley, Maximilian Diehn, Herve Ghesquieres, Ash A. Alizadeh
Journal: Blood
Blood (2024) 144 (Supplement 1): 853.
https://doi.org/10.1182/blood-2024-201644
Published: 2024
Journal Articles

FISHing for clarity in double-hit lymphomas

Stefan K. Alig
Journal: Blood
Blood (2024) 144 (15): 1550–1552.
https://doi.org/10.1182/blood.2024026379
Published: 2024
Journal Articles

CAR19 Therapy Drives Expansion of Clonal Hematopoiesis and Associated Cytopenias

Mark P. Hamilton, Brian J. Sworder, Stefan K. Alig, Zinaida Good, Jan Boegeholz, Joseph Schroers-Martin, John Tamaresis, Mohammad Shahrokh Esfahani, Ying Lu, Mari Olsen, Chih Long Liu, Zachary Ehlinger, Moksha Desai, Felicia Liu-Fei, Lori S. Muffly, Robert S. Negrin, Sally Arai, Laura Johnston, Robert Lowsky, Everett H. Meyer, Andrew R. Rezvani, Judith Shizuru, Wen-Kai Weng, Parveen Shiraz, Surbhi Sidana, Sushma Bharadwaj, Melody Smith, Saurabh Dahiya, Bita Sahaf, Maximilian Diehn, Matthew J. Frank, Crystal L. Mackall, David M. Kurtz, David B. Miklos, Ash A. Alizadeh
Journal: Blood
Blood (2023) 142 (Supplement 1): 360.
https://doi.org/10.1182/blood-2023-182522
Published: 2023
Journal Articles

Inferred Gene Expression By Cell-Free DNA Profiling Allows Noninvasive Lymphoma Classification

Jurik A Mutter, Mohammad Shahrokh Esfahani, Joseph Schroers-Martin, Stefan K. Alig, Mark P. Hamilton, Brian J. Sworder, Benoit Tessoulin, Jan Boegeholz, Timothy Flerlage, Jamie E. Flerlage, Michael S. Binkley, Takeshi Sugio, Cédric Rossi, Mari Olsen, Chih Long Liu, Steven Le Gouill, David M. Kurtz, Maximilian Diehn, Ash A. Alizadeh
Journal: Blood
Blood (2023) 142 (Supplement 1): 245.
https://doi.org/10.1182/blood-2023-186853
Published: 2023
Journal Articles

Genomic, Transcriptional, and Immunological Validation of Distinct Molecular Subtypes of Classic Hodgkin Lymphoma through Tissue-Based and Noninvasive Methods

Stefan K. Alig, Mohammad Shahrokh Esfahani, Andrea Garofalo, Michael Yu Li, Cédric Rossi, Timothy Flerlage, Jamie E. Flerlage, Ragini Adams, Michael S. Binkley, Navika Shukla, Michael Jin, Mari Olsen, Adele Telenius, Jurik A Mutter, Joseph Schroers-Martin, Brian J. Sworder, Shinya Rai, Daniel King, Andre Schultz, Jan Lukas Bögeholz, Shengqin Su, Karan R Kathuria, Chih Long Liu, Xiaoman Kang, Deanna M. Langfitt, Kristine Faye Pobre-Piza, Feng Tian, Maya J. Strohband, Valeria Spina, Thomas Tousseyn, Lieselot Buedts, Luc-Matthieu Fornecker, Sharon M. Castellino, Ranjana H. Advani, Davide Rossi, Ryan C Lynch, Herve Ghesquieres, Olivier Casasnovas, David M. Kurtz, Lianna J. Marks, Michael P. Link, Marc Andre, Peter Vandenberghe, Christian Steidl, Maximilian Diehn, Ash A. Alizadeh
Journal: Blood
Blood (2023) 142 (Supplement 1): 177.
https://doi.org/10.1182/blood-2023-186810
Published: 2023
Journal Articles

Investigating the Cell States and Prognostic Impact of Tumor Microenvironment Ecosystems in Classic Hodgkin Lymphoma

Shengqin Su, Ajay Subramanian, Timothy Flerlage, Jamie E. Flerlage, Stefan K. Alig, Everett J. Moding, Richard T. Hoppe, Ranjana H. Advani, Yasodha Natkunam, Ash A. Alizadeh, Michael S. Binkley
Journal: Blood
Blood (2023) 142 (Supplement 1): 3016.
https://doi.org/10.1182/blood-2023-180288
Published: 2023
Journal Articles

Distinct Circulating Genomic Features of Classical Hodgkin Lymphoma of Older Adults

Cédric Rossi, Jan Boegeholz, Stefan K. Alig, Andrea Garofalo, Mohammad Shahrokh Esfahani, Joseph Schroers-Martin, Mari Olsen, Xiaoman Kang, David M. Kurtz, Takeshi Sugio, Mark P. Hamilton, Marc Andre, Rene-Olivier Casasnovas, Luc Matthieu Fornecker, Maximilian Diehn, Herve Ghesquieres, Ash A. Alizadeh
Journal: Blood
Blood (2023) 142 (Supplement 1): 4369.
https://doi.org/10.1182/blood-2023-178257
Published: 2023
Journal Articles

Optimizing Circulating Tumor DNA Limits of Detection for DLBCL during First Line Therapy

Jordan Goldstein, Won Seog Kim, Sang Eun Yoon, Seok Jin Kim, Mark Roschewski, Jason Westin, Ryan C Lynch, Stefan K. Alig, Sandra Close, Jacob J. Chabon, Davide Rossi, Wyndham H Wilson, Maximilian Diehn, Ash A. Alizadeh, David M. Kurtz
Journal: Blood
Blood (2023) 142 (Supplement 1): 187.
https://doi.org/10.1182/blood-2023-187759
Published: 2023
Journal Articles

Durable Remissions in Advanced Stage and Molecularly High Risk Untreated Classic Hodgkin Lymphoma with Pembrolizumab + AVD

Ryan C Lynch, Stefan K. Alig, Chaitra S Ujjani, Christina Poh, Edus H Warren, Stephen D Smith, Mazyar Shadman, Brian G Till, Vikram Raghunathan, Yolanda D Tseng, Susan Ottemiller, Bonnie Joy, Melissa Mary Fessel, Hongyan Du, Jacquelin Vandermeer, Alyssa Kelly, Heather Rasmussen, Jenna M Voutsinas, Qian Wu, Ash A. Alizadeh, Ajay K Gopal
Journal: Blood
Blood (2023) 142 (Supplement 1): 4429.
https://doi.org/10.1182/blood-2023-179547
Published: 2023
Journal Articles

Longitudinal Noninvasive Surveillance & Fragmentomic Characterization of Follicular Lymphoma

Joseph Schroers-Martin, Jurik A Mutter, Mohammad Shahrokh Esfahani, Florian Scherer, Joanne Soo, Stefan K. Alig, David M. Kurtz, Takeshi Sugio, Cédric Rossi, Benoit Tessoulin, Mari Olsen, Chih Long Liu, Maximilian Diehn, Ash A. Alizadeh
Journal: Blood
Blood (2023) 142 (Supplement 1): 528.
https://doi.org/10.1182/blood-2023-187116
Published: 2023
Journal Articles

An Integrated Multimodal Framework for Noninvasive TCL Disease Detection and Monitoring

Takeshi Sugio, Navika Shukla, Michael S Khodadoust, Monica Nesselbush, Koji Kato, Stefan K. Alig, Jan Boegeholz, Joseph Schroers-Martin, Mohammad Shahrokh Esfahani, Jurik A. Mutter, Andrea Garofalo, Soyeong Jun, Mark P. Hamilton, Cédric Rossi, Mari Olsen, Chih Long Liu, Koichi Akashi, Maximilian Diehn, Ash A. Alizadeh
Journal: Blood
Blood (2023) 142 (Supplement 1): 1620.
https://doi.org/10.1182/blood-2023-180492
Published: 2023
Journal Articles

Viral cfDNA Profiling Reveals Distinct EBV Subtypes and Stratifies Risk in Hodgkin Lymphomas

Andrea Garofalo, Stefan K. Alig, Joseph Schroers-Martin, Ragini Malika Shyam, Mari Olsen, David M. Kurtz, Cédric Rossi, Andre Schultz, Karan R. Kathuria, Chih Long Liu, Valeria Spina, Jamie E. Flerlage, Sharon M. Castellino, Ranjana H. Advani, Davide Rossi, Ryan C. Lynch, Olivier Casasnovas, Lianna J. Marks, Michael P. Link, Marc Andre, Peter Vandenberghe, Christian Steidl, Maximilian Diehn, Ash A. Alizadeh
Journal: Blood
Blood (2022) 140 (Supplement 1): 1318–1319.
https://doi.org/10.1182/blood-2022-159230
Published: 2022
Journal Articles

Circulating Tumor DNA in Untreated Classical Hodgkin Lymphoma Patients Treated with Pembrolizumab and Chemotherapy: Dynamic Response Assessment and Correlation with Baseline Metabolic Tumor Volume

Ryan C. Lynch, Stefan K. Alig, Chaitra S. Ujjani, Christina Poh, Edus H. Warren, Stephen D. Smith, Mazyar Shadman, Andrei Shustov, Brian G. Till, Vikram Raghunathan, Yolanda D. Tseng, Hilary Coye, Megan Shelby, Susan Ottemiller, Sarith Keo, Kaitlin Verni, Hongyan Du, Jacquelin Vandermeer, Ashley Gaston, Heather A. Rasmussen, Avanti Gulhane, Delphine Chen, Eric Wayne Dean, Paul S. Martin, Edmond A Marzbani, Jenna M. Voutsinas, Ash A. Alizadeh, Ajay K. Gopal
Journal: Blood
Blood (2022) 140 (Supplement 1): 6547–6549.
https://doi.org/10.1182/blood-2022-160234
Published: 2022