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Tomohiro Aoki
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Journal Articles

Limited-stage Mantle Cell Lymphoma: Real-world outcomes according to nodal vs. extranodal presentation

Free
Sun-Hye Ko, Michael Crump, John Kuruvilla, David Hodgson, Danielle Rodin, Tomohiro Aoki, Sita Bhella, Robert Kridel, Vishal Kukreti, Nauman Malik, Abi Vijenthira, Chloe Yang, Anca Prica
Journal: Blood
Blood (2025) 146 (Supplement 1): 2769.
https://doi.org/10.1182/blood-2025-2769
Published: 2025
Journal Articles

Outcomes and treatment strategies following CD20/CD3 bispecific antibody failure in non-Hodgkin's lymphoma: A retrospective single-center study

Free
Sun-Hye Ko, Tomohiro Aoki, Robert Kridel, Vishal Kukreti, Anca Prica, Abi Vijenthira, Chloe Yang, Michael Crump, John Kuruvilla
Journal: Blood
Blood (2025) 146 (Supplement 1): 4550.
https://doi.org/10.1182/blood-2025-4550
Published: 2025
Journal Articles

Radiotherapy consolidation post-autologous stem cell transplant in Relapsed/Refractory aggressive non-Hodgkin lymphoma improves progression-free and overall survival in patients with partial but not complete metabolic response pre-transplant

Free
Joshua Yi, Chathuri Abeyakoon, David Hodgson, Vanessa Murad, Ho-Young Yhim, Meenakshi Jeeva, Inna Gong, John Kuruvilla, Michael Crump, Anca Prica, Vishal Kukreti, Sita Bhella, Chloe Yang, Tomohiro Aoki, Danielle Rodin, Woodrow Wells, Nauman Malik, Ur Metser, Robert Kridel, Abi Vijenthira
Journal: Blood
Blood (2025) 146 (Supplement 1): 7188.
https://doi.org/10.1182/blood-2025-7188
Published: 2025
Journal Articles

Multimodal single-cell and spatial analyses reveal a distinct immune ecosystem in pediatric classic Hodgkin lymphoma

Free
Shinichiro Oshima, Yifan Yin, Nawar Dakhallah, Rose Chami, Bo Ngan, Angela Punnett, Hang Yin, Isabella Kong, Shinya Rai, Adele Telenius, Robert Kridel, Federico Gaiti, David Scott, Kara Kelly, Debra Friedman, Sharon Castellino, Lisa Roth, Christian Steidl, Tomohiro Aoki
Journal: Blood
Blood (2025) 146 (Supplement 1): 3552.
https://doi.org/10.1182/blood-2025-3552
Published: 2025
Journal Articles

Somatic IRF4 mutations and thymic tropism in primary mediastinal large B-cell lymphoma

Available to Purchase
Shinya Rai, Gerben Duns, Fabian Frontzek, Jasper C. H. Wong, Yifan Yin, Michael Yu Li, Makoto Kishida, Manabu Fujisawa, Shannon Healy, Elena Viganò, Aixiang Jiang, Bruce Woolcock, Adèle Telenius, Susana Ben-Neriah, Barbara Meissner, Merrill Boyle, Hisae Nakamura, Luke O’Brien, Claudia Cassidy, Andrew Lytle, Pedro Farinha, Graham Slack, Laura K. Hilton, Ryan D. Morin, Leandro Venturutti, Tomohiro Aoki, Nicole Wretham, Jonathan W. Bush, Laura Evgin, Kerry J. Savage, David W. Scott, Christian Steidl
Journal: Blood
Blood (2025) 146 (13): 1586–1600.
https://doi.org/10.1182/blood.2025028412
Published: 2025
Includes: Supplemental data
Journal Articles

Multiomic Profiling Reveals Pleiotropic Effects of Somatic IRF4-C99R Mutations in Primary Mediastinal Large B-Cell Lymphomas

Free
Shinya Rai, Gerben Duns, Fabian Frontzek, Jasper Wong, Yifan Yin, Shannon Healy, Michael Yu Li, Makoto Kishida, Elena Viganò, Manabu Fujisawa, Bruce Woolcock, Adele Telenius, Barbara Meissner, Merrill Boyle, Hisae Nakamura, Luke O'Brien, Andrew Lytle, Pedro Farinha, Graham W. Slack, Laura K. Hilton, Ryan Morin, Leandro Venturutti, Tomohiro Aoki, Kerry J. Savage, David W. Scott, Christian Steidl
Journal: Blood
Blood (2024) 144 (Supplement 1): 2966.
https://doi.org/10.1182/blood-2024-199227
Published: 2024
Journal Articles

Multiome Single Cell Analyses Identify a Distinct CD8+ T Cell Phenotype Linked to Treatment Response in PTLD

Free
Tomohiro Aoki, Davidson Zhao, Noémie Lang, Yifan Yin, Ting Liu, Michael Hong, Johanna Regala, Troy Ketela, Anca Prica, John Kuruvilla, Pedro Farinha, Jan Delabie, Federico Gaiti, Kerry J. Savage, David W. Scott, Robert Kridel
Journal: Blood
Blood (2024) 144 (Supplement 1): 4385.
https://doi.org/10.1182/blood-2024-194926
Published: 2024
Journal Articles

Tumor Microenvironment Differences between Diagnostic and Relapsed Classic Hodgkin Lymphoma Revealed By Single Cell Transcriptome Sequencing

Free
Yifan Yin, Tomohiro Aoki, Shinya Rai, Aixiang Jiang, Alexander Xu, Luke O'Brien, Jan Delabie, Lauren Camille Chong, Stacy Hung, Akil Merchant, David W. Scott, Kerry J. Savage, Christian Steidl
Journal: Blood
Blood (2024) 144 (Supplement 1): 646.
https://doi.org/10.1182/blood-2024-209760
Published: 2024
Journal Articles

CSF2RB Mutations Result in Cytokine-Dependent Gain-of-Function Phenotypes in Classic Hodgkin Lymphoma

Free
Shinya Rai, Tomohiro Aoki, Gerben Duns, Aixiang Jiang, Andrew Lytle, Yifan Yin, Makoto Kishida, Michael Yu Li, Denise Smorra, Cecilia Lee, Katy Milne, Adele Telenius, Luke O'Brien, Katsuyoshi Takata, Tomoko Miyata-Takata, Merrill Boyle, Susana Ben-Neriah, Andrew P. Weng, Andrew Roth, Brad H NelsonH, Laura K. Hilton, Pedro Farinha, Kerry J. Savage, David W. Scott, Christian Steidl
Journal: Blood
Blood (2024) 144 (Supplement 1): 855.
https://doi.org/10.1182/blood-2024-199981
Published: 2024
Journal Articles

Evaluation of a Prognostic 23-Gene Expression Panel in a Set of 390 Multiethnic Hodgkin Lymphoma Patients

Free
Anthony Colombo, Jia Yin Wan, Aixiang Jiang, Jose Aparicio, Esther Lam, Tomohiro Aoki, Joo Y Song, Sheeja Pullarkat, Chun Chao, Juan Manuel Mejia-Arangure, Brenda Hernandez, Pamela B. Allen, Christopher R. Flowers, Sophia S. Wang, Juanita Evans, Owen Chan, Jakub Svoboda, Anja Mottok, Leon Bernal-Mizrachi, Megan Lim, David W. Scott, Imran Siddiqi, David Conti, Christian Steidl, Wendy Cozen
Journal: Blood
Blood (2023) 142 (Supplement 1): 4379.
https://doi.org/10.1182/blood-2023-182906
Published: 2023
Journal Articles

EBV Prevalence and Overall Survival in the M ulti e thnic S tudy of H odgkin Lymphoma (MESH)

Free
Esther Lam, Jia Yin Wan, Jose Aparicio, Sheeja Pullarkat, Anthony Colombo, Joo Y Song, Chun Chao, Juan Manuel Mejia-Arangure, Brenda Hernandez, Aixiang Jiang, Tomohiro Aoki, Pamela B. Allen, Christopher R. Flowers, Sophia S. Wang, Juanita Evans, Owen Chan, Leon Bernal-Mizrachi, David W. Scott, Megan Lim, Jakub Svoboda, Christian Steidl, Anja Mottok, David Conti, Imran Siddiqi, Wendy Cozen
Journal: Blood
Blood (2023) 142 (Supplement 1): 6188.
https://doi.org/10.1182/blood-2023-182919
Published: 2023
Journal Articles

Multi-Dimensional Molecular and Tumor-Microenvironment Analysis of Classic Hodgkin Lymphoma

Free
Tomohiro Aoki, Gerben Duns, Shinya Rai, Andrew Lytle, Yifan Yin, Clementine Sarkozy, Stacy Hung, Katy Milne, Adele Telenius, Luke O'Brien, Celia Strong, Talia Goodyear, Shaocheng Wu, Katsuyoshi Takata, Tomoko Miyata-Takata, Merrill Boyle, Susana Ben-Neriah, Andrew P. Weng, Andrew Roth, Anca Prica, Robert Kridel, Brad Nelson, Pedro Farinha, Kerry J. Savage, David W. Scott, Christian Steidl
Journal: Blood
Blood (2023) 142 (Supplement 1): 172.
https://doi.org/10.1182/blood-2023-174139
Published: 2023
Journal Articles

Novel insights into Hodgkin lymphoma biology by single-cell analysis

Free
Tomohiro Aoki, Christian Steidl
Journal: Blood
Blood (2023) 141 (15): 1791–1801.
https://doi.org/10.1182/blood.2022017147
Published: 2023
Journal Articles

Spatial Protein Analysis of the Tumor Microenvironment and Biomarkers in Hodgkin's Lymphoma

Free
Alexander Xu, Tomohiro Aoki, Aixiang Jiang, Alicia Gamboa, Anthony R. Colombo, Christian Steidl, Akil Merchant
Journal: Blood
Blood (2022) 140 (Supplement 1): 3564–3565.
https://doi.org/10.1182/blood-2022-170737
Published: 2022
Journal Articles

Spatial Tumor Microenvironment Characterization and Outcome of Relapsed/Refractory Classic Hodgkin Lymphoma

Free
Tomohiro Aoki, Aixiang Jiang, Alexander Xu, Alicia Gamboa, Yifan Yin, Katy Milne, Celia Strong, Talia Goodyear, Shaocheng Wu, Lauren C. Chong, Katsuyoshi Takata, Elizabeth Chavez, Tomoko Miyata-Takata, Anthony R. Colombo, Monirath Hav, Adele Telenius, Susana Ben-Neriah, Andrew P. Weng, Kerry J. Savage, David W. Scott, Andrew Roth, Pedro Farinha, Brad H Nelson, Akil Merchant, Christian Steidl
Journal: Blood
Blood (2022) 140 (Supplement 1): 170–171.
https://doi.org/10.1182/blood-2022-158709
Published: 2022
Journal Articles

TRAF3 Loss-of-Function Reveals the Non-Canonical NF-Κb Pathway As a Therapeutic Target in Diffuse Large B-Cell Lymphoma

Free
Michael Y. Li, Lauren C. Chong, Bruce W Woolcock, Adèle Telenius, Susana Ben-Neriah, Graham W Slack, Vivian Lam, Aixiang Jiang, Elena Viganò, Tomohiro Aoki, Shannon Healy, Gerald Krystal, Leandro Venturutti, David W. Scott, Christian Steidl
Journal: Blood
Blood (2022) 140 (Supplement 1): 2042–2043.
https://doi.org/10.1182/blood-2022-159679
Published: 2022
Journal Articles

Integrated Single Cell Analysis Reveals Co-Evolution of Malignant B Cells and the Tumor Microenvironment in Transformed Follicular Lymphoma

Free
Clementine Sarkozy, Shaocheng Wu, Katsuyoshi Takata, Tomohiro Aoki, Susana Ben-Neriah, Katy Milne, Brad H Nelson, Andrew P. Weng, David W. Scott, Jeffrey W. Craig, Christian Steidl, Andrew Roth
Journal: Blood
Blood (2022) 140 (Supplement 1): 750–751.
https://doi.org/10.1182/blood-2022-160405
Published: 2022
Journal Articles

Single-Cell Profiling Reveals Clinically Relevant Evolutionary Trajectories and Alternate Biologies in Human Follicular Lymphoma

Free
Xuehai Wang, Michael Nissen, Deanne Gracias, Manabu Kusakabe, Guillermo Simkin, Gerben Duns, Clementine Sarkozy, Elizabeth Chavez, Gabriela Cristina Segat, Jubin Kim, Aixiang Jiang, Tomohiro Aoki, Rashedul Islam, Christina May, Stacy Hung, Kateryna Tyshchenko, Ryan Brinkman, Martin Hirst, Aly Karsan, Ciara L. Freeman, Laurie H. Sehn, Kerry J. Savage, Jeffrey W Craig, David W. Scott, Christian Steidl, Sohrab P Shah, Andrew P. Weng
Journal: Blood
Blood (2021) 138 (Supplement 1): 450.
https://doi.org/10.1182/blood-2021-153237
Published: 2021
Journal Articles

Immune Profiling of Diagnostic DLBCL Biopsies Dramatically Improves upon Cell-of-Origin Risk Stratification

Free
Michael Nissen, Xuehai Wang, Clementine Sarkozy, Aixiang Jiang, Daisuke Ennishi, Tomohiro Aoki, Stacy Hung, Elizabeth Chavez, Jeffrey W Craig, Pedro Farinha, Graham W. Slack, David W. Scott, Christian Steidl, Andrew P. Weng
Journal: Blood
Blood (2021) 138 (Supplement 1): 719.
https://doi.org/10.1182/blood-2021-154082
Published: 2021
Journal Articles

Mutational landscape of gray zone lymphoma

Free
Clémentine Sarkozy, Stacy S. Hung, Elizabeth A. Chavez, Gerben Duns, Katsuyoshi Takata, Lauren C. Chong, Tomohiro Aoki, Aixiang Jiang, Tomoko Miyata-Takata, Adèle Telenius, Graham W. Slack, Thierry Jo Molina, Susana Ben-Neriah, Pedro Farinha, Peggy Dartigues, Diane Damotte, Anja Mottok, Gilles A. Salles, Rene-Olivier Casasnovas, Kerry J. Savage, Camille Laurent, David W. Scott, Alexandra Traverse-Glehen, Christian Steidl
Journal: Blood
Blood (2021) 137 (13): 1765–1776.
https://doi.org/10.1182/blood.2020007507
Published: 2021
Includes: Supplemental data