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Daisuke Ennishi
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Journal Articles

Oral Inflammation and Microbiome Dysbiosis Exacerbate Chronic Graft-versus-host Disease

Yui Kambara, Hideaki Fujiwara, Akira Yamamoto, Kazuyoshi Gotoh, Shuma Tsuji, Mari Kunihiro, Tadashi Oyama, Toshiki Terao, Ayame Sato, Takehiro Tanaka, Daniel Peltier, Keisuke Seike, Hisakazu Nishimori, Noboru Asada, Daisuke Ennishi, Keiko Fujii, Nobuharu Fujii, Ken-ichi Matsuoka, Yoshihiko Soga, Pavan Reddy, Yoshinobu Maeda
Journal: Blood
Blood blood.2024024540.
https://doi.org/10.1182/blood.2024024540
Published: 2024
Includes: Supplemental data
Journal Articles

Identification of a Novel Function of B2M Involving T-Cell Exhaustion Via P-Selectin Ligand Upregulation in Diffuse Large B-Cell Lymphoma

Katsuyoshi Takata, Hidekazu IIoka, Shuta Tomida, Yuting Liu, Shujiro Okuda, Hiroyuki Usuda, Takashi Kawasaki, Akihiro Kitadate, Naoto Takahashi, Gerben Duns, Yasuharu Sato, Christian Steidl, Daisuke Ennishi
Journal: Blood
Blood (2024) 144 (Supplement 1): 331.
https://doi.org/10.1182/blood-2024-202199
Published: 2024
Journal Articles

Dynamic Shifts in Inflammation and Fibrotic Remodeling in Post-HSCT Bronchiolitis Obliterans: A Spatial Transcriptomics Study

Akira Yamamoto, Nobuharu Fujii, Keisuke Seike, Seiichiro Sugimoto, Yusuke Naoi, Yui Kambara, Kanako Fujiwara, Toshiki Terao, Tadashi Oyama, Mari Kunihiro, Takumi Kondo, Hiroki Kobayashi, Hideaki Fujiwara, Noboru Asada, Daisuke Ennishi, Keiko Fujii, Shinichi Toyooka, Yoshinobu Maeda
Journal: Blood
Blood (2024) 144 (Supplement 1): 7101.
https://doi.org/10.1182/blood-2024-202251
Published: 2024
Journal Articles

Single-Cell DNA Sequencing Reveals Cell-Level Genetic Evolutionary Processes and Clonal Structure in B-Cell Lymphomas

Hiroyuki Murakami, Ryota Chijimatsu, Hideki Ujiie, Yusuke Naoi, Kazutaka Sunami, Kazuhiko Yamamoto, Soichiro Fujii, Tomofumi Yano, Keisuke Seike, Hideaki Fujiwara, Noboru Asada, Nobuharu Fujii, Ken-ichi Matsuoka, Tomohiro Urata, Kazuhiro Ikeuchi, Hiroki Kobayashi, Yasuharu Sato, Shuta Tomida, Yoshinobu Maeda, Daisuke Ennishi
Journal: Blood
Blood (2024) 144 (Supplement 1): 1368.
https://doi.org/10.1182/blood-2024-198983
Published: 2024
Journal Articles

A Multicenter, Prospective, Observational Study of Pola-R-CHP in Patients with Previously Untreated Diffuse Large B-Cell Lymphoma (POLASTAR): A Preliminary Analysis

Hirohiko Shibayama, Atsushi Satake, Kohta Miyawaki, Yuki Fujiwara, Shuichi Ota, Tsuyoshi Muta, Shinya Rai, Hisashi Tsurumi, Ritsuro Suzuki, Takaaki Miyake, Hideki Goto, Noriko Fukuhara, Mamiko Sakata-Yanagimoto, Koji Izutsu, Momoko Nishikori, Takahiro Kumode, Daisuke Ennishi, Takayuki Shimose, Naoki Inubashiri, Itaru Matsumura, Koichi Akashi, Koji Kato
Journal: Blood
Blood (2024) 144 (Supplement 1): 4475.
https://doi.org/10.1182/blood-2024-192949
Published: 2024
Journal Articles

Pirtobrutinib, a Highly Selective, Non-Covalent (Reversible) BTK Inhibitor in Relapsed/Refractory Follicular Lymphoma: Results from the Phase 1/2 BRUIN Study

Nirav N. Shah, Pier Luigi Zinzani, Michael L. Wang, Sunita D. Nasta, Ewa Lech-Maranda, Yoshiaki Ogawa, Bita Fakhri, Bryone Kuss, Kaname Miyashita, Krish Patel, Catherine C. Coombs, Shuo Ma, Manish Patel, Minal A. Barve, Benoit Tessoulin, Anastasios Stathis, Won Seog Kim, Daisuke Ennishi, Daigo Hashimoto, Kensuke Kojima, Andrew D. Zelenetz, Jonathon B. Cohen, Julie M. Vose, Kami J. Maddocks, Talha Munir, Fangfang Sun, Faith Bian, Donald E. Tsai, Paolo Abada, Chan Y. Cheah
Journal: Blood
Blood (2023) 142 (Supplement 1): 3026.
https://doi.org/10.1182/blood-2023-181309
Published: 2023
Journal Articles

Single Cell Multi Omics and Spatial Analysis Reveals Plasmablast Signature Malignant Cells As a Key of Intratumor Heterogeneity in Primary Central Nervous System Lymphoma

Hiroki Kobayashi, Ryota Chijimatsu, Ryo Mizuta, Kentaro Fujii, Yoshihiro Otani, Joji Ishida, Yusuke Naoi, Hiroyuki Murakami, Hideki Ujiie, Kazuhiro Ikeuchi, Tomohiro Urata, Katsuma Tani, Akira Yamamoto, Keisuke Seike, Hideaki Fujiwara, Noboru Asada, Hisakazu Nishimori, Keiko Fujii, Nobuharu Fujii, Ken-ichi Matsuoka, Yasuharu Sato, Tadashi Yoshino, Yoshinobu Maeda, Daisuke Ennishi
Journal: Blood
Blood (2023) 142 (Supplement 1): 2998.
https://doi.org/10.1182/blood-2023-174410
Published: 2023
Journal Articles

CD79 Expression Is Associated with Cell-of-Origin and Outcome in Diffuse Large B-Cell Lymphoma

Yusuke Naoi, Ryota Chijimatsu, Tomohiro Urata, Kazutaka Sunami, Toshi Imai, Yuichiro Nawa, Yasushi Hiramatsu, Kazuhiko Yamamoto, Soichiro Fujii, Isao Yoshida, Tomofumi Yano, Kazuhiro Ikeuchi, Hiroki Kobayashi, Katsuma Tani, Hiroyuki Murakami, Hideki Ujiie, Yasuharu Sato, Katsuyoshi Takata, Merrill Boyle, Aixiang Jiang, Yoshinobu Maeda, David W. Scott, Daisuke Ennishi
Journal: Blood
Blood (2023) 142 (Supplement 1): 1760.
https://doi.org/10.1182/blood-2023-172972
Published: 2023
Journal Articles

Gilteritinib Maintenance Therapy Post-Allogenic Stem-Cell Transplantation Improves the Prognosis of Patients with FLT3-Mutated AML

Toshiki Terao, Ken-ichi Matsuoka, Hiroko Ueda, Akifumi Matsumura, Chisato Matsubara, Kaho Kondo, Takumi Kondo, Hideaki Fujiwara, Noboru Asada, Daisuke Ennishi, Hisakazu Nishimori, Keiko Fujii, Nobuharu Fujii, Yoshinobu Maeda
Journal: Blood
Blood (2022) 140 (Supplement 1): 3290–3291.
https://doi.org/10.1182/blood-2022-163876
Published: 2022
Journal Articles

Influence of Oral Microbiota on Chronic Graft-Versus-Host Disease and Its Role As a Therapeutic Target

Yui Kambara, Hideaki Fujiwara, Akira Yamamoto, Mari Kunihiro, Tadashi Oyama, Takumi Kondo, Noboru Asada, Daisuke Ennishi, Hisakazu Nishimori, Nobuharu Fujii, Keiko Fujii, Ken-ichi Matsuoka, Yoshinobu Maeda
Journal: Blood
Blood (2022) 140 (Supplement 1): 10202–10203.
https://doi.org/10.1182/blood-2022-162323
Published: 2022
Journal Articles

Clinical Impact of Cell-of-Origin and Double-Hit Signature of DLBCL in Japan

Tomohiro Urata, Kazutaka Sunami, Toshi Imai, Yuichiro Nawa, Yasushi Hiramatsu, Kazuhiko Yamamoto, Soichiro Fujii, Isao Yoshida, Tomofumi Yano, Yusuke Naoi, Kazuhiro Ikeuchi, Hiroki Kobayashi, Katsuma Tani, Shuji Momose, Jun-ichi Tamaru, Merrill Boyle, Aixiang Jiang, Yasuharu Sato, Tadashi Yoshino, Yoshinobu Maeda, David W. Scott, Daisuke Ennishi
Journal: Blood
Blood (2022) 140 (Supplement 1): 6421–6423.
https://doi.org/10.1182/blood-2022-157702
Published: 2022
Journal Articles

Impact of the Dose of Post-Transplant Cyclophosphamide and the Start Timing of Tacrolimus in Patients Who Received Allogeneic Stem-Cell Transplantation from Haploidentical Donor

Toshiki Terao, Ken-ichi Matsuoka, Hiroki Takasuka, Takumi Kondo, Chihiro Kamoi, Hiroko Ueda, Akifumi Matsumura, Chisato Matsubara, Kaho Kondo, Hideaki Fujiwara, Noboru Asada, Daisuke Ennishi, Hisakazu Nishimori, Keiko Fujii, Nobuharu Fujii, Yoshinobu Maeda
Journal: Blood
Blood (2022) 140 (Supplement 1): 12867–12868.
https://doi.org/10.1182/blood-2022-166571
Published: 2022
Journal Articles

Immune Profiling of Diagnostic DLBCL Biopsies Dramatically Improves upon Cell-of-Origin Risk Stratification

Michael Nissen, Xuehai Wang, Clementine Sarkozy, Aixiang Jiang, Daisuke Ennishi, Tomohiro Aoki, Stacy Hung, Elizabeth Chavez, Jeffrey W Craig, Pedro Farinha, Graham W. Slack, David W. Scott, Christian Steidl, Andrew P. Weng
Journal: Blood
Blood (2021) 138 (Supplement 1): 719.
https://doi.org/10.1182/blood-2021-154082
Published: 2021
Journal Articles

Characterization of DLBCL with a PMBL gene expression signature

Gerben Duns, Elena Viganò, Daisuke Ennishi, Clementine Sarkozy, Stacy S. Hung, Elizabeth Chavez, Katsuyoshi Takata, Christopher Rushton, Aixiang Jiang, Susana Ben-Neriah, Bruce W. Woolcock, Graham W. Slack, Eric D. Hsi, Jeffrey W. Craig, Laura K. Hilton, Sohrab P. Shah, Pedro Farinha, Anja Mottok, Randy D. Gascoyne, Ryan D. Morin, Kerry J. Savage, David W. Scott, Christian Steidl
Journal: Blood
Blood (2021) 138 (2): 136–148.
https://doi.org/10.1182/blood.2020007683
Published: 2021
Includes: Supplemental data
Journal Articles

The impact of MYC and BCL2 structural variants in tumors of DLBCL morphology and mechanisms of false-negative MYC IHC

Brett Collinge, Susana Ben-Neriah, Lauren Chong, Merrill Boyle, Aixiang Jiang, Tomoko Miyata-Takata, Pedro Farinha, Jeffrey W. Craig, Graham W. Slack, Daisuke Ennishi, Anja Mottok, Barbara Meissner, Elizabeth A. Chavez, Alina S. Gerrie, Diego Villa, Ciara Freeman, Kerry J. Savage, Laurie H. Sehn, Ryan D. Morin, Andrew J. Mungall, Randy D. Gascoyne, Marco A. Marra, Joseph M. Connors, Christian Steidl, David W. Scott
Journal: Blood
Blood (2021) 137 (16): 2196–2208.
https://doi.org/10.1182/blood.2020007193
Published: 2021
Includes: Supplemental data
Journal Articles

The Tumor Associated Antigen PRAME Exhibits Dualistic Functions That Are Targetable in Diffuse Large B-Cell Lymphoma

Katsuyoshi Takata, MD PhD, Lauren C. Chong, MSc, Daisuke Ennishi, MD PhD, Avinash Thakur, PhD, Shannon Healy, PhD, Elena Viganò, PhD, Tao Dao, MD PhD, Julie S Nielsen, Susana Ben-Neriah, BSc, Tomohiro Aoki, MD PhD, Ethan Tse, Stacy Hung, Michael Y. Li, BS, Merrill Boyle, BSc, Sung Soo Mun, Christopher Bourne, Bruce W Woolcock, Adele Telenius, Allen Zhang, Ali Bashashati, Saeed Saberi, Gianluca D' Antonio, Brad H Nelson, Sohrab P Shah, Pamela Hoodless, Ari Melnick, MD, Randy D. Gascoyne, MD, Joseph M Connors, MD, David A. Scheinberg, MD PhD, Wendy Béguelin, PhD, David W. Scott, MBChB, PhD, Christian Steidl, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 34.
https://doi.org/10.1182/blood-2020-141168
Published: 2020
Journal Articles

Favorable Outcomes of Newly Diagnosed Intravascular Large B-Cell Lymphoma Patients Treated with R-CHOP Combined with High-Dose Methotrexate Plus Intrathecal Chemotherapy: Results from a Multicenter Phase 2 Trial (PRIMEUR-IVL)

Kazuyuki Shimada, MD, Motoko Yamaguchi, MD PhD, Yoshiko Atsuta, MD PhD, Kosei Matsue, MD PhD, Keijiro Sato, MD, Shigeru Kusumoto, MD PhD, Hirokazu Nagai, MD PhD, Jun Takizawa, MD PhD, Noriko Fukuhara, MD PhD, Koji Nagafuji, MD PhD, Kana Miyazaki, MD PhD, Eiichi Ohtsuka, MD, Masataka Okamoto, MD PhD, Yasumasa Sugita, MD PhD, Toshiki Uchida, MD PhD, Satoshi Kayukawa, MD, Atsushi Wake, MD PhD, Daisuke Ennishi, MD PhD, Yukio Kondo, MD, Tohru Izumi, MD, Yoshihiro Kin, MD, Kunihiro Tsukasaki, MD PhD, Daigo Hashimoto, Masaaki Yuge, MD PhD, Atsumi Yanagisawa, Yachiyo Kuwatsuka, MD PhD, Satoko Shimada, MD, Yasufumi Masaki, MD PhD, Nozomi Niitsu, MD PhD, Hitoshi Kiyoi, MD PhD, Ritsuro Suzuki, MD PhD, Takashi Tokunaga, MD PhD, Shigeo Nakamura, MD, Tomohiro Kinoshita, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 350.
https://doi.org/10.1182/blood-2019-126798
Published: 2019
Journal Articles

TP53 Expression Correlates with TP53 Mutations and Is an Independent Predictor of Clinical Outcome in Patients with DLBCL Treated with R-CHOP

Pedro Farinha, MD PhD, Daisuke Ennishi, MD PhD, Anja Mottok, MD PhD, Susana Ben-Neriah, BSc, Barbara Meissner, PhD, Merrill Boyle, BSc, Jeffrey W. Craig, MD PhD, Graham W Slack, MD, Diego Villa, MD MPH, Kerry J Savage, BSc, MD MSc, Laurie H Sehn, MD, Ryan D. Morin, PhD, Marco A. Marra, PhD, Joseph M. Connors, MD, Randy D. Gascoyne, MD, Christian Steidl, MD, David W. Scott, MBChB, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3964.
https://doi.org/10.1182/blood-2019-121943
Published: 2019
Journal Articles

Molecular Correlates of Central Nervous System Relapse in Diffuse Large B-Cell Lymphoma

Robert Kridel, MDMPH,PhD, Keren Isaev, MSc, Daisuke Ennishi, MD PhD, Brian Skinnider, MD, Karen Mungall, PhD, Andrew J. Mungall, PhD, Mehran Bakhtiari, MSc, Rosemarie Tremblay-Lemay, MD MSc, FRCPC, Barbara Meissner, PhD, Susana Ben-Neriah, BSc, Merrill Boyle, BSc, Diego Villa, MD MPH, Marco A. Marra, PhD, Christian Steidl, MD, Randy D. Gascoyne, MD, Kerry J Savage, BSc, MD MSc, David W. Scott, MBChB, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2763.
https://doi.org/10.1182/blood-2019-124235
Published: 2019
Journal Articles

Diffuse Large B-Cell Lymphomas with a Molecular PMBCL Expression Signature Represent a Distinct Molecular Subtype Associated with Poor Clinical Outcome

Gerben Duns, PhD, Elena Viganò, PhD, Daisuke Ennishi, MD PhD, Clementine Sarkozy, MD, Stacy Hung, Elizabeth Chavez, Katsuyoshi Takata, MD PhD, Anja Mottok, MD PhD, Randy D. Gascoyne, MD, Ryan D. Morin, PhD, Kerry J Savage, BSc, MD MSc, David W. Scott, MBChB, PhD, Christian Steidl, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 922.
https://doi.org/10.1182/blood-2019-131450
Published: 2019