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Journal Articles

Oral Inflammation and Microbiome Dysbiosis Exacerbate Chronic Graft-versus-host Disease

Yui Kambara, Hideaki Fujiwara, Akira Yamamoto, Kazuyoshi Gotoh, Shuma Tsuji, Mari Kunihiro, Tadashi Oyama, Toshiki Terao, Ayame Sato, Takehiro Tanaka, Daniel Peltier, Keisuke Seike, Hisakazu Nishimori, Noboru Asada, Daisuke Ennishi, Keiko Fujii, Nobuharu Fujii, Ken-ichi Matsuoka, Yoshihiko Soga, Pavan Reddy, Yoshinobu Maeda
Journal: Blood
Blood blood.2024024540.
https://doi.org/10.1182/blood.2024024540
Published: 2024
Includes: Supplemental data
Journal Articles

Dynamic Shifts in Inflammation and Fibrotic Remodeling in Post-HSCT Bronchiolitis Obliterans: A Spatial Transcriptomics Study

Akira Yamamoto, Nobuharu Fujii, Keisuke Seike, Seiichiro Sugimoto, Yusuke Naoi, Yui Kambara, Kanako Fujiwara, Toshiki Terao, Tadashi Oyama, Mari Kunihiro, Takumi Kondo, Hiroki Kobayashi, Hideaki Fujiwara, Noboru Asada, Daisuke Ennishi, Keiko Fujii, Shinichi Toyooka, Yoshinobu Maeda
Journal: Blood
Blood (2024) 144 (Supplement 1): 7101.
https://doi.org/10.1182/blood-2024-202251
Published: 2024
Journal Articles

Efficacy and Safety of Cyclosporine Monotherapy for Patients with Non-Severe Aplastic Anemia Not Requiring Transfusions: Results from a Prospective Multicenter Phase II Study

Naoko Hosono, Ken Ishiyama, Hiroki Yamaguchi, Masahide Yamazaki, Hiroyuki Maruyama, Kensuke Usuki, Kazuki Tanimoto, Hiroyuki Sugiura, Noboru Asada, Seishi Ogawa, Yuzuru Kanakura, Itaru Matsumura, Koichi Akashi, Shinji Nakao
Journal: Blood
Blood (2024) 144 (Supplement 1): 1312.
https://doi.org/10.1182/blood-2024-198830
Published: 2024
Journal Articles

Alpha 2-Adrenergic Agonist As a Novel Microenvironment-Directed Agent for Acute Myeloid Leukemia Via Notch Signaling Inhibition

Wataru Kitamura, Masakazu Shinohara, Akifumi Matsumura, Takashi Moriyama, Masaya Abe, Yayoi Ueda, Shinichi Ishii, Tomohide Suzuki, Mitsuaki Ono, Yoshinobu Maeda, Noboru Asada
Journal: Blood
Blood (2024) 144 (Supplement 1): 1297.
https://doi.org/10.1182/blood-2024-204949
Published: 2024
Journal Articles

Single-Cell DNA Sequencing Reveals Cell-Level Genetic Evolutionary Processes and Clonal Structure in B-Cell Lymphomas

Hiroyuki Murakami, Ryota Chijimatsu, Hideki Ujiie, Yusuke Naoi, Kazutaka Sunami, Kazuhiko Yamamoto, Soichiro Fujii, Tomofumi Yano, Keisuke Seike, Hideaki Fujiwara, Noboru Asada, Nobuharu Fujii, Ken-ichi Matsuoka, Tomohiro Urata, Kazuhiro Ikeuchi, Hiroki Kobayashi, Yasuharu Sato, Shuta Tomida, Yoshinobu Maeda, Daisuke Ennishi
Journal: Blood
Blood (2024) 144 (Supplement 1): 1368.
https://doi.org/10.1182/blood-2024-198983
Published: 2024
Journal Articles

Single Cell Multi Omics and Spatial Analysis Reveals Plasmablast Signature Malignant Cells As a Key of Intratumor Heterogeneity in Primary Central Nervous System Lymphoma

Hiroki Kobayashi, Ryota Chijimatsu, Ryo Mizuta, Kentaro Fujii, Yoshihiro Otani, Joji Ishida, Yusuke Naoi, Hiroyuki Murakami, Hideki Ujiie, Kazuhiro Ikeuchi, Tomohiro Urata, Katsuma Tani, Akira Yamamoto, Keisuke Seike, Hideaki Fujiwara, Noboru Asada, Hisakazu Nishimori, Keiko Fujii, Nobuharu Fujii, Ken-ichi Matsuoka, Yasuharu Sato, Tadashi Yoshino, Yoshinobu Maeda, Daisuke Ennishi
Journal: Blood
Blood (2023) 142 (Supplement 1): 2998.
https://doi.org/10.1182/blood-2023-174410
Published: 2023
Journal Articles

Alpha-Pinene As a Novel Therapeutic Agent for T-Cell Tumors

Masaya Abe, Noboru Asada, Maiko Kimura, Chie Fukui, Daisuke Yamada, Ziyi Wang, Masayuki Miyake, Takeshi Takarada, Mitsuaki Ono, Michinori Aoe, Wataru Kitamura, Masayuki Matsuda, Takashi Moriyama, Akifumi Matsumura, Yoshinobu Maeda
Journal: Blood
Blood (2023) 142 (Supplement 1): 1441.
https://doi.org/10.1182/blood-2023-181447
Published: 2023
Journal Articles

Phase 1/2 First-in-Human Study of the Menin-MLL Inhibitor DSP-5336 in Patients with Relapsed or Refractory Acute Leukemia

Naval Daver, Joshua F. Zeidner, Junichiro Yuda, Justin M. Watts, Mark J. Levis, Kentaro Fukushima, Takayuki Ikezoe, Yoshiaki Ogawa, Joseph Brandwein, Eunice S. Wang, Yasushi Miyazaki, Timothy Pardee, Naoko Hosono, Takahiro Shima, Hisayuki Yokoyama, Noboru Asada, Joseph Jurcic, Hongliang Cai, Akinobu Watanabe, Matthew Hitron, Emily Brooks, Bo Xu, Jatin Shah, Hagop M. Kantarjian, Harry P. Erba
Journal: Blood
Blood (2023) 142 (Supplement 1): 2911.
https://doi.org/10.1182/blood-2023-179252
Published: 2023
Journal Articles

Gilteritinib Maintenance Therapy Post-Allogenic Stem-Cell Transplantation Improves the Prognosis of Patients with FLT3-Mutated AML

Toshiki Terao, Ken-ichi Matsuoka, Hiroko Ueda, Akifumi Matsumura, Chisato Matsubara, Kaho Kondo, Takumi Kondo, Hideaki Fujiwara, Noboru Asada, Daisuke Ennishi, Hisakazu Nishimori, Keiko Fujii, Nobuharu Fujii, Yoshinobu Maeda
Journal: Blood
Blood (2022) 140 (Supplement 1): 3290–3291.
https://doi.org/10.1182/blood-2022-163876
Published: 2022
Journal Articles

Influence of Oral Microbiota on Chronic Graft-Versus-Host Disease and Its Role As a Therapeutic Target

Yui Kambara, Hideaki Fujiwara, Akira Yamamoto, Mari Kunihiro, Tadashi Oyama, Takumi Kondo, Noboru Asada, Daisuke Ennishi, Hisakazu Nishimori, Nobuharu Fujii, Keiko Fujii, Ken-ichi Matsuoka, Yoshinobu Maeda
Journal: Blood
Blood (2022) 140 (Supplement 1): 10202–10203.
https://doi.org/10.1182/blood-2022-162323
Published: 2022
Journal Articles

Risk Stratified Therapy with Nelarabine and Intensified Administration of L-Asparaginase for Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia in Adolescents and Young Adults (JPLSG T-11/JALSG T-ALL-211-U): An Intergroup Phase 2 Study

Yoshihiro Hatta, Atsushi Sato, Akiko Kada, Akiko Moriya Saito, Fumihiko Hayakawa, Arata Watanabe, Tatsuhiro Sakamoto, Katsuhiro Miura, Yoshifumi Shimizu, Junya Kanda, Yasushi Onishi, Noboru Asada, Yasuhiro Okamoto, Chihaya Imai, Koichi Oshima, Katsuyoshi Koh, Atsushi Manabe, Keizo Horibe, Hitoshi Kiyoi, Itaru Matsumura, Yasushi Miyazaki
Journal: Blood
Blood (2022) 140 (Supplement 1): 124–126.
https://doi.org/10.1182/blood-2022-156613
Published: 2022
Journal Articles

Impact of the Dose of Post-Transplant Cyclophosphamide and the Start Timing of Tacrolimus in Patients Who Received Allogeneic Stem-Cell Transplantation from Haploidentical Donor

Toshiki Terao, Ken-ichi Matsuoka, Hiroki Takasuka, Takumi Kondo, Chihiro Kamoi, Hiroko Ueda, Akifumi Matsumura, Chisato Matsubara, Kaho Kondo, Hideaki Fujiwara, Noboru Asada, Daisuke Ennishi, Hisakazu Nishimori, Keiko Fujii, Nobuharu Fujii, Yoshinobu Maeda
Journal: Blood
Blood (2022) 140 (Supplement 1): 12867–12868.
https://doi.org/10.1182/blood-2022-166571
Published: 2022
Journal Articles

FGF-23 from erythroblasts promotes hematopoietic progenitor mobilization

Shinichi Ishii, Tomohide Suzuki, Kanako Wakahashi, Noboru Asada, Yuko Kawano, Hiroki Kawano, Akiko Sada, Kentaro Minagawa, Yukio Nakamura, Seiya Mizuno, Satoru Takahashi, Toshimitsu Matsui, Yoshio Katayama
Journal: Blood
Blood (2021) 137 (11): 1457–1467.
https://doi.org/10.1182/blood.2020007172
Published: 2021
Includes: Supplemental data
Journal Articles

No Evidence for Hematopoietic Stem Cell Self-Renewal in-Vivo Following Inflammatory Challenge

Ruzhica Bogeska, PhD, Paul Kaschutnig, PhD, Stella V Paffenholz, MSc, Julia Knoch, Jan-Philipp Mallm, PhD, Malak Fawaz, MSc, Florian Buettner, PhD, Dagmar Walter, PhD, Felix Frauhammer, MSc, Tim Holland-Letz, PhD, Noboru Asada, MD PhD, Ana-Matea Mikecin Drazic, PhD, Marleen Buechler-Schaff, MSc, Martha Correno-Gonzalez, Melanie Ball, Sina Staeble, MSc, Julius Gräsel, PhD, Simon Haas, PhD, Daniel B. Lipka, MD, Karsten Rippe, PhD, Benedikt Brors, PhD, Paul S. Frenette, MD, Michael A. Rieger, Marieke A. G. Essers, PhD, Michael D. Milsom, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 456.
https://doi.org/10.1182/blood-2019-125744
Published: 2019
Journal Articles

Dasatinib-Based Two-Step Induction Prior to Allogeneic Hematopoietic Cell Transplantation for Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: Results of the JALSG Ph+ALL213 Study

Isamu Sugiura, MD, Noriko Doki, MD PhD, Tomoko Hata, MD, PhD, Ryuko CHO, MD PhD, Toshiro Ito, MD, Youko Suehiro, MD PhD, Heiwa Kanamori, MD PhD, Shinichi Kako, MD, Mitsuhiro Matsuda, MD PhD, Hisayuki Yokoyama, MD PhD, Yasuhiro Taniguchi, MD, Maki Hagihara, MD PhD, Yukiyasu Ozawa, MD PhD, Shin Fujisawa, MD PhD, Nobuaki Dobashi, MD, Yoshihiro Hatta, MD, Noboru Asada, MD PhD, Kazuteru Ohashi, MD PhD, Yasushi Onishi, MD PhD, Koh Shiro, MD PhD, Satoshi Nishiwaki, MD PhD, Yoshiko Atsuta, MD PhD, Fumihiko Hayakawa, MD PhD, Shigeki Ohtake, MD PhD, Yasushi Miyazaki, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 743.
https://doi.org/10.1182/blood-2019-123382
Published: 2019
Journal Articles

Vitamin D receptor–mediated skewed differentiation of macrophages initiates myelofibrosis and subsequent osteosclerosis

Kanako Wakahashi, Kentaro Minagawa, Yuko Kawano, Hiroki Kawano, Tomohide Suzuki, Shinichi Ishii, Akiko Sada, Noboru Asada, Mari Sato, Shigeaki Kato, Kotaro Shide, Kazuya Shimoda, Toshimitsu Matsui, Yoshio Katayama
Journal: Blood
Blood (2019) 133 (15): 1619–1629.
https://doi.org/10.1182/blood-2018-09-876615
Published: 2019
Includes: Supplemental data
Journal Articles

Prospective Evaluation of Prognostic Relevance of KIT Mutations in Core-Binding Factor Acute Myeloid Leukemia: Results from the JALSG CBF-AML209-KIT Study

Naomi Kawashima, MD, Yuichi Ishikawa, MD PhD, Yoshiko Atsuta, MD PhD, Isamu Sugiura, MD, Masashi Sawa, MD PhD, Nobuaki Dobashi, MD, Hisayuki Yokoyama, MD PhD, Noriko Doki, MD PhD, Akihiro Tomita, MD PhD, Toru Kiguchi, MD PhD, Shiro Koh, MD, Heiwa Kanamori, MD PhD, Noriyoshi Iriyama, MD PhD, Akio Kohno, MD, Yukiyoshi Moriuchi, MD, Noboru Asada, MD PhD, Daiki Hirano, MD, Kazuto Togitani, MD, Toru Sakura, PhD MD, Maki Hagihara, MD PhD, Tatsuki Tomikawa, MD PhD, Yasuhisa Yokoyama, MDPhD, Norio Asou, MDPhD, Shigeki Ohtake, MD PhD, Itaru Matsumura, MD, Yasushi Miyazaki, MD PhD, Tomoki Naoe, MD PhD, Hitoshi Kiyoi, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 438.
https://doi.org/10.1182/blood-2018-99-113931
Published: 2018
Journal Articles

TFL Deletion Induces Incredible CXCL13 Secretion and Cachexia in Vavp - Bcl2 T ransgenic Mice

Kentaro Minagawa, MDPhD, Kanako Wakahashi, MD PhD, Fukui Chie, Shinichiro Nishikawa, MD PhD, Noboru Asada, MD PhD, Yuko Kawano, MD PhD, Hiroki Kawano, MD PhD, Tomohide Suzuki, MD, Shinichi Ishii, MD, Yoshio Katayama, MD PhD, Toshimitsu Matsui, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3908.
https://doi.org/10.1182/blood-2018-99-114351
Published: 2018
Journal Articles

Efficacy of HLA-Matched PLT Transfusions for Platelet Transfusion Refractoriness in HSCT Patients

Keisuke Seike, Nobuharu Fujii, MD PhD, Keiko Fujii, MD PhD, Yasuhisa Sando, MD, Makoto Nakamura, MD, Kyosuke Saeki, MD, Yusuke Meguri, MD, Noboru Asada, MD PhD, Daisuke Ennishi, MDPhD, Hisakazu Nishimori, MD PhD, Ken-Ichi Matsuoka, MD PhD, Yoshinobu Maeda, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1265.
https://doi.org/10.1182/blood-2018-99-112365
Published: 2018
Journal Articles

Granulocyte Transfusions for Neutropenic Patients Receiving Allogeneic Hematopoietic Stem Cell Transplantation

Shuntaro Ikegawa, MD, Nobuharu Fujii, MD PhD, Keiko Fujii, MD PhD, Yusuke Meguri, MD, Kyosuke Saeki, MD, Noboru Asada, MD PhD, Hisakazu Nishimori, MD PhD, Ken-ichi Matsuoka, MDPhD, Yoshinobu Maeda, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2410.
https://doi.org/10.1182/blood.V130.Suppl_1.2410.2410
Published: 2017