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Journal Articles

Prognostic Impact of Graft-Versus-Host Disease on Allogeneic Transplantation for CMML Focusing on Conditioning Intensity

Hidehiro Itonaga, Yasushi Miyazaki, Machiko Fujioka, Shuhei Kurosawa, Yasunobu Nagata, Yutaka Shimazu, Tomoaki Ueda, Naoyuki Uchida, Noriko Doki, Tetsuya Nishida, Ken-ichi Matsuoka, Masatsugu Tanaka, Makoto Yoshimitsu, Yoshinobu Kanda, Tatsuo Ichinohe, Yoshiko Atsuta, Takayoshi Tachibana
Journal: Blood
Blood (2024) 144 (Supplement 1): 6755.
https://doi.org/10.1182/blood-2024-193699
Published: 2024
Journal Articles

Molecular Taxonomy Classification for Transplant Decision Making of Myelodysplastic Syndromes

Rurika Okuda, Yotaro Ochi, Tetsuichi Yoshizato, Yasuhito Nannya, Yoshiko Atsuta, Yuichi Shiraishi, Yusuke Shiozawa, Hiroko Tanaka, Makoto Onizuka, Kenichi Chiba, Hidehiro Itonaga, Yoshinobu Kanda, Yasushi Miyazaki, Keizo Horibe, Satoru Miyano, Hideki Makishima, Seishi Ogawa
Journal: Blood
Blood (2024) 144 (Supplement 1): 3203.
https://doi.org/10.1182/blood-2024-206498
Published: 2024
Journal Articles

Optimal Procedures of Allogeneic Transplantation for BCR::ABL1 -Negative Atypical Chronic Myeloid Leukemia

Hidehiro Itonaga, Yasushi Miyazaki, Takeshi Kondo, Yutaka Shimazu, Jun Aoki, Shuhei Kurosawa, Takashi Ikeda, Tetsuya Eto, Naoyuki Uchida, Hideyuki Nakazawa, Koji Kawamura, Junya Kanda, Yoshiko Atsuta, Takayoshi Tachibana
Journal: Blood
Blood (2024) 144 (Supplement 1): 4548.
https://doi.org/10.1182/blood-2024-193697
Published: 2024
Journal Articles

Efficacy of Cord Blood Transplantation for the Management of Chronic Myelomonocytic Leukemia: A Registry-Based Study in Japan

Shuhei Kurosawa, Yoshimitsu Shimomura, Ken Ishiyama, Kyoko Fuse, Yutaka Shimazu, Noriko Doki, Naoyuki Uchida, Masatsugu Tanaka, Satoshi Takahashi, Masatoshi Sakurai, Hikaru Kobayashi, Yuta Katayama, Satoru Takada, Kazutaka Ozeki, Hirohisa Nakamae, Fumihiko Ishimaru, Yoshinobu Kanda, Tatsuo Ichinohe, Yoshiko Atsuta, Hidehiro Itonaga
Journal: Blood
Blood (2023) 142 (Supplement 1): 3577.
https://doi.org/10.1182/blood-2023-173603
Published: 2023
Journal Articles

Impact of Conditioning Intensity and Regimen on Outcomes after Unrelated Cord Blood Transplantation for Patients with Myelodysplastic Syndrome

Machiko Fujioka, Hidehiro Itonaga, Yasushi Miyazaki, Yoshimitsu Shimomura, Naoyuki Uchida, Satoshi Takahashi, Makoto Onizuka, Yasunori Ueda, Yasufumi Uehara, Masatsugu Tanaka, Yoshiko Matsuhashi, Shigesaburo Miyakoshi, Haruyuki Tanaka, Toshiro Kawakita, Fumihiko Ishimaru, Junya Kanda, Tatsuo Ichinohe, Yoshiko Atsuta, Ken Ishiyama
Journal: Blood
Blood (2023) 142 (Supplement 1): 3536.
https://doi.org/10.1182/blood-2023-179157
Published: 2023
Journal Articles

Prognostic Impact of Conditioning Intensity on Outcomes after Allogeneic Transplantation for MDS with Low Blasts

Hidehiro Itonaga, Yasushi Miyazaki, Machiko Fujioka, Ken Ishiyama, Jun Aoki, Noriko Doki, Tetsuya Nishida, Takahiro Fukuda, Naoyuki Uchida, Yasunori Ueda, Yasufumi Uehara, Yuta Katayama, Makoto Onizuka, Tatsuo Ichinohe, Yoshiko Atsuta
Journal: Blood
Blood (2023) 142 (Supplement 1): 4985.
https://doi.org/10.1182/blood-2023-173567
Published: 2023
Journal Articles

Effect of Early Cytomegalovirus Reactivation on Relapse in Adult Patients with Myelodysplastic Syndromes after Allogeneic Hematopoietic Stem Cell Transplantation: A Registry Study from the Japan Society for Transplantation and Cellular Therapy (JSTCT)

Tatsuya Konishi, Kensuke Matsuda, Hidehiro Itonaga, Noriko Doki, Tetsuya Nishida, Ken-Ichi Matsuoka, Takashi Ikeda, Yoshinobu Kanda, Takahiro Fukuda, Junya Kanda, Hirohisa Nakamae, Tatsuo Ichinohe, Yoshiko Atsuta, Ken Ishiyama
Journal: Blood
Blood (2023) 142 (Supplement 1): 2170.
https://doi.org/10.1182/blood-2023-172414
Published: 2023
Journal Articles

Outcomes of Allogeneic Transplantation for Adult T-Cell Leukemia/Lymphoma in Adolescents and Young Adult (AYA) and Young Patients

Hidehiro Itonaga, Takuya Fukushima, Koji Kato, Nobuaki Nakano, Takeharu Kato, Takashi Tanaka, Tetsuya Eto, Yasuo Mori, Toshiro Kawakita, Naoyuki Uchida, Yasushi Sawayama, Takahiro Fukuda, Yoshinobu Kanda, Yoshiko Atsuta, Makoto Yoshimitsu, Shigeo Fuji
Journal: Blood
Blood (2023) 142 (Supplement 1): 1707.
https://doi.org/10.1182/blood-2023-173590
Published: 2023
Journal Articles

Arginine Methylation of BRD4 By CARM1 Regulates Its Function in AML

Adnan K. Mookhtiar, Hidehiro Itonaga, Sarah Greenblatt, Concepcion Martinez, Jun Sun, Krystal Lisa Hossack, Ramin Shiekhattar, Daniel Bilbao, Maria Ken E. Figueroa, Simone Sidoli, Stephen D. Nimer
Journal: Blood
Blood (2023) 142 (Supplement 1): 4112.
https://doi.org/10.1182/blood-2023-189759
Published: 2023
Journal Articles

Germ line DDX41 mutations define a unique subtype of myeloid neoplasms

Hideki Makishima, Ryunosuke Saiki, Yasuhito Nannya, Sophia Korotev, Carmelo Gurnari, June Takeda, Yukihide Momozawa, Steve Best, Pramila Krishnamurthy, Tetsuichi Yoshizato, Yoshiko Atsuta, Yusuke Shiozawa, Yuka Iijima-Yamashita, Kenichi Yoshida, Yuichi Shiraishi, Yasunobu Nagata, Nobuyuki Kakiuchi, Makoto Onizuka, Kenichi Chiba, Hiroko Tanaka, Ayana Kon, Yotaro Ochi, Masahiro M. Nakagawa, Rurika Okuda, Takuto Mori, Akinori Yoda, Hidehiro Itonaga, Yasushi Miyazaki, Masashi Sanada, Takayuki Ishikawa, Shigeru Chiba, Hisashi Tsurumi, Senji Kasahara, Carsten Müller-Tidow, Akifumi Takaori-Kondo, Kazuma Ohyashiki, Toru Kiguchi, Fumihiko Matsuda, Joop H. Jansen, Chantana Polprasert, Piers Blombery, Yoichiro Kamatani, Satoru Miyano, Luca Malcovati, Torsten Haferlach, Michiaki Kubo, Mario Cazzola, Austin G. Kulasekararaj, Lucy A. Godley, Jaroslaw P. Maciejewski, Seishi Ogawa
Journal: Blood
Blood (2023) 141 (5): 534–549.
https://doi.org/10.1182/blood.2022018221
Published: 2023
Includes: Supplemental data
Journal Articles

Germline Risks and Clinical Impacts of DDX41 Mutations in Myeloid Malignancies

Hideki Makishima, Ryunosuke Saiki, Yasuhito Nannya, Sophia C. Korotev, Carmelo Gurnari, June Takeda, Yukihide Momozawa, Steve Best, Pramila Krishnamurthy, Tetsuichi Yoshizato, Yoshiko Atsuta, Yusuke Shiozawa, Yuka Iijima-Yamashita, Kenichi Yoshida, Yuichi Shiraishi, Yasunobu Nagata, Nobuyuki Kakiuchi, Makoto Onizuka, Kenichi Chiba, Hiroko Tanaka, Ayana Kon, Yotaro Ochi, Masahiro Marshall Nakagawa, Rurika Okuda, Takuto Mori, Akinori Yoda, Hidehiro Itonaga, Yasushi Miyazaki, Masashi Sanada, Takayuki Ishikawa, Shigeru Chiba, Hisashi Tsurumi, Senji Kasahara, Carsten Müller-Tidow, Akifumi Takaori-Kondo, Kazuma Ohyashiki, Toru Kiguchi, Fumihiko Matsuda, Joop H. Jansen, Chantana Polprasert, Piers Blombery, Yoichiro Kamatani, Satoru Miyano, Luca Malcovati, Torsten Haferlach, Michiaki Kubo, Mario Cazzola, Austin Kulasekararaj, Lucy A. Godley, Jaroslaw P. Maciejewski, Seishi Ogawa
Journal: Blood
Blood (2022) 140 (Supplement 1): 208–210.
https://doi.org/10.1182/blood-2022-158851
Published: 2022
Journal Articles

Tyrosine Phosphorylation of CARM1 Promotes Its Enzymatic Activity and Alters Its Target Specificity in Myeloid Neoplasms with Hyperactivated JAK2

Hidehiro Itonaga, Adnan K Mookhtiar, Sarah Greenblatt, Fan Liu, Concepcion Martinez, Renata Grozovsky, Daniel Bilbao, Masai Rains, Pierre-Jacques Hamard, Jun Sun, Afoma Umeano, Stephanie Duffort, Chuan Chen, Na Man, Gloria Mas Martin, Stephen Schürer, Stephen D Nimer
Journal: Blood
Blood (2022) 140 (Supplement 1): 3021–3022.
https://doi.org/10.1182/blood-2022-156887
Published: 2022
Journal Articles

The NLRC4 Inflammasome Drives Myelodysplastic Syndrome By Linking Epigenetic Reprogramming and Innate Immune Signaling

Chuan Chen, Na Man, Francesco Tamiro, Krystal Hossack, Julio Poveda, Daniel Bilbao, Gloria Mas, Stephanie Duffort, Concepcion Martinez, Hidehiro Itonaga, Fan Liu, Jennifer R Chapman-Fredricks, Stephen D Nimer
Journal: Blood
Blood (2022) 140 (Supplement 1): 3009–3010.
https://doi.org/10.1182/blood-2022-160075
Published: 2022
Journal Articles

Comparison of Myeloablative Versus Reduced-Intensity Fludarabine/Busulfan Regimen in Patients with Myelodysplastic Syndrome Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Shuhei Kurosawa, Yoshimitsu Shimomura, Hidehiro Itonaga, Yuho Najima, Takeshi Kobayashi, Yukiyasu Ozawa, Yoshinobu Kanda, Shinichi Kako, Toshiro Kawakita, Ken-Ichi Matsuoka, Yumiko Maruyama, Shuichi Ota, Hideyuki Nakazawa, Kazunori Imada, Takafumi Kimura, Junya Kanda, Takahiro Fukuda, Yoshiko Atsuta, Ken Ishiyama
Journal: Blood
Blood (2021) 138 (Supplement 1): 3692.
https://doi.org/10.1182/blood-2021-144689
Published: 2021
Journal Articles

Clinical Impacts of Germline DDX41 Mutations on Myeloid Neoplasms

Hideki Makishima, MD PhD, Yasuhito Nannya, MD PhD, June Takeda, MD, Yukihide Momozawa, DVM,PhD, Ryunosuke Saiki, MD, Tetsuichi Yoshizato, MD PhD, Yoshiko Atsuta, MD PhD, Yuka Iijima-Yamashita, Kenichi Yoshida, MD PhD, Yuichi Shiraishi, PhD, Yasunobu Nagata, MD PhD, Yusuke Shiozawa, MD PhD, Makoto Onizuka, MD PhD, Kenichi Chiba, Hiroko Tanaka, Nobuyuki Kakiuchi, MD, Yotaro Ochi, MD, Hiroo Ueno, MD PhD, Hidehiro Itonaga, MD PhD, Yoshinobu Kanda, MD PhD, Masashi Sanada, MD, Ayana Kon, MD PhD, Yasushi Miyazaki, MD PhD, Keizo Horibe, MD PhD, Maria Creignou, Magnus Tobiasson, MD, Hisashi Tsurumi, MD PhD, Senji Kasahara, MD PhD, Chantana Polprasert, MD, Eva Hellstrom Lindberg, MD PhD, Akifumi Kondo Takaori, MD PhD, Toru Kiguchi, MD PhD, Mario Cazzola, MD, Fumihiko Matsuda, MD PhD, Kazuma Ohyashiki, MD PhD, Jaroslaw P. Maciejewski, MD PhD, Torsten Haferlach, MD, Yoichiro Kamatani, MDPhD, Michiaki Kubo, MDPhD, Satoru Miyano, PhD, Seishi Ogawa, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 38–40.
https://doi.org/10.1182/blood-2020-140174
Published: 2020
Journal Articles

The Baf Subunit Dpf2 Regulates Resolution of Inflammation By Controlling Macrophage Differentiation Transcription Factor Networks

Gloria Mas Martin, PhD, Na Man, Daniel Karl, PhD, Concepcion Martinez, B.S., Stephanie Duffort, Hidehiro Itonaga, MD PhD, Adnan K Mookhtiar, BS, Daniel Bilbao, PhD, Kranthi Kunkalla, Alfredo M Valencia, Clayton Collings, Cigall Kadoch, PhD, Francisco Vega, MDPhD, Scott C. Kogan, MD, Stephen Nimer, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 13.
https://doi.org/10.1182/blood-2020-142030
Published: 2020
Journal Articles

EP300 Suppresses Leukemia Development in Myelodysplastic Syndrome through Myb Repression

Na Man, Gloria Mas Martin, PhD, Daniel Karl, PhD, Jun Sun, PhD, Fan Liu, PhD, Miguel Torres-Martin, PhD, Hidehiro Itonaga, MD PhD, Concepcion Martinez, B.S., Shi Chen, Stephanie Duffort, Pierre-Jacques Hamard, PhD, Ye Xu, PhD, Luisa Cimmino, PhDBSc, Feng-Chun Yang, MD PhD, Philip A. Cole, MD PhD, Mingjiang Xu, MD PhD, Maria E. Figueroa, MD, Stephen Nimer, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 561.
https://doi.org/10.1182/blood-2019-130507
Published: 2019
Journal Articles

PPM1D and DNMT3A Mutations in Myelodysplasia and Clonal Hematopoiesis

Masanori Motomura, Yoshikage Inoue, Yasunobu Nagata, MD PhD, Tetsuichi Yoshizato, MD PhD, Constance Baer, PhD, Yukihide Momozawa, Niroshan Nadarajah, Yasuhito Nannya, MD PhD, Kenichi Yoshida, MD PhD, Claudia Haferlach, MD, Wolfgang Kern, MD, Yoshiko Atsuta, MD PhD, Yuka Iijima-Yamashita, Yuichi Shiraishi, PhD, Makoto Onizuka, MD PhD, Kenichi Chiba, PhD, Hiroko Tanaka, BA, Hidehiro Itonaga, MD PhD, Yasushi Miyazaki, MD PhD, Keizo Horibe, MD PhD, Masashi Sanada, MD, Yoichiro Kamatani, Michiaki Kubo, MD PhD, Satoru Miyano, PhD, Torsten Haferlach, MD, Seishi Ogawa, MD PhD, Hideki Makishima, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1709.
https://doi.org/10.1182/blood-2019-122032
Published: 2019
Journal Articles

Integrated Analysis of Copy-Number Alterations and Gene Mutations in 2,000 Patients with Myeloid Neoplasms

Ryunosuke Saiki, Yusuke Shiozawa, MD PhD, Tetsuichi Yoshizato, MD PhD, Yasuhito Nannya, MD PhD, June Takeda, MD, Kenichi Yoshida, MD PhD, Yuichi Shiraishi, PhD, Hiroko Tanaka, BA, Kenichi Chiba, PhD, Yoshiko Atsuta, MD PhD, Makoto Onizuka, MD PhD, Hidehiro Itonaga, MD PhD, Masashi Sanada, MD, Yoshinobu Kanda, MD PhD, Bartlomiej Przychodzen, Mikkael A. Sekeres, MD MS, Kathryn Guinta, Yogenthiran Saunthararajah, MD, Lee-Yung Shih, MD, Shuichi Miyawaki, MD PhD, Tsuyoshi Nakamaki, MD PhD, Masataka Taguchi, Shigeo Fuji, MD PhD, Nana Sasaki, MD, Nobuhiko Uoshima, MD PhD, Yasunori Ueda, MD PhD, Yasushi Miyazaki, MD PhD, Kensuke Usuki, MD PhD, Kazunori Imada, MD PhD, Akifumi Takaori-Kondo, MD PhD, Shigeru Chiba, MD PhD, Senji Kasahara, MD PhD, Toru Kiguchi, MD PhD, Hisashi Tsurumi, MD PhD, Luca Malcovati, MD, Mario Cazzola, MD, Takayuki Ishikawa, MD PhD, Satoru Miyano, PhD, Jaroslaw P. Maciejewski, MD PhD, Hideki Makishima, MD PhD, Seishi Ogawa, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4216.
https://doi.org/10.1182/blood-2019-132174
Published: 2019
Journal Articles

Genomic Analysis of Myelodysplastic Syndromes Among Nagasaki Atomic Bomb Survivors

Masataka Taguchi, Hiroyuki Mishima, DDS, PhD, Yusuke Shiozawa, MD, PhD, Chisa Hayashida, Akira Kinoshita, PhD, Shinya Sato, MD, PhD, Makiko Horai, MD, PhD, Masatoshi Matsuo, MD, PhD, Hidehiro Itonaga, MD, PhD, Takeharu Kato, MD, PhD, Hiroaki Taniguchi, MD, PhD, Daisuke Imanishi, MD, PhD, Yoshitaka Imaizumi, MD, PhD, Tomoko Hata, MD, PhD, Motoi Takenaka, MD, PhD, Hideki Makishima, MD PhD, Yasuhito Nannya, MD PhD, Yukiyoshi Moriuchi, MD, Seishi Ogawa, MD PhD, Koh-ichiro Yoshiura, MD, PhD, Yasushi Miyazaki, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4341.
https://doi.org/10.1182/blood-2018-99-113735
Published: 2018