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Pierre-Jacques Hamard
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Journal Articles

Tyrosine Phosphorylation of CARM1 Promotes Its Enzymatic Activity and Alters Its Target Specificity in Myeloid Neoplasms with Hyperactivated JAK2

Hidehiro Itonaga, Adnan K Mookhtiar, Sarah Greenblatt, Fan Liu, Concepcion Martinez, Renata Grozovsky, Daniel Bilbao, Masai Rains, Pierre-Jacques Hamard, Jun Sun, Afoma Umeano, Stephanie Duffort, Chuan Chen, Na Man, Gloria Mas Martin, Stephen Schürer, Stephen D Nimer
Journal: Blood
Blood (2022) 140 (Supplement 1): 3021–3022.
https://doi.org/10.1182/blood-2022-156887
Published: 2022
Journal Articles

EP300 Suppresses Leukemia Development in Myelodysplastic Syndrome through Myb Repression

Na Man, Gloria Mas Martin, PhD, Daniel Karl, PhD, Jun Sun, PhD, Fan Liu, PhD, Miguel Torres-Martin, PhD, Hidehiro Itonaga, MD PhD, Concepcion Martinez, B.S., Shi Chen, Stephanie Duffort, Pierre-Jacques Hamard, PhD, Ye Xu, PhD, Luisa Cimmino, PhDBSc, Feng-Chun Yang, MD PhD, Philip A. Cole, MD PhD, Mingjiang Xu, MD PhD, Maria E. Figueroa, MD, Stephen Nimer, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 561.
https://doi.org/10.1182/blood-2019-130507
Published: 2019
Journal Articles

CARM1/PRMT4 As a Novel Therapeutic Target for AML

Sarah Greenblatt, PhD, Na Man, Pierre-Jacques Hamard, PhD, Concepcion Martinez, B.S., Ye Xu, PhD, Fan Liu, PhD, Justin M Watts, MD, Daniel G. Tenen, MD, Stephen D. Nimer, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 241.
https://doi.org/10.1182/blood.V130.Suppl_1.241.241
Published: 2017
Journal Articles

PRMT5 Regulates DNA Repair By Controlling the Alternative Splicing of Epigenetic Factors

Pierre-Jacques Hamard, PhD, Gabriel Emmanuel Santiago, Fan Liu, PhD, Sarah Greenblatt, PhD, Daniel Karl, PhD, Concepcion Martinez, B.S., Ramiro E Verdun, PhD, Stephen D. Nimer, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1148.
https://doi.org/10.1182/blood.V130.Suppl_1.1148.1148
Published: 2017
Journal Articles

The AML-Associated FLT3-ITD Kinase Regulates Histone Modifications and Cytokine Signaling, Via Effects on PRMT5

Koji Ando, MD PhD, Pierre-Jacques Hamard, PhD, Fan Liu, PhD, Concepcion Martinez, Yuguang Ban, PhD, Xi Chen, PhD, Stephen D. Nimer, MD
Journal: Blood
Blood (2016) 128 (22): 2696.
https://doi.org/10.1182/blood.V128.22.2696.2696
Published: 2016
Journal Articles

Prmt5 Negatively Regulates Erythropoiesis By Multiple Mechanisms, Including Controlling DNA Methyltransferase 3A Protein Levels

Pierre-Jacques Hamard, PhD, Luisa Luciani, PhD, Fan Liu, PhD, Guoyan Cheng, PhD, Megan A. Hatlen, PhD, Olga A Guryanova, MD, PhD, Xinyang Zhao, PhD, Ross L. Levine, MD, Stephen D. Nimer, MD
Journal: Blood
Blood (2015) 126 (23): 1181.
https://doi.org/10.1182/blood.V126.23.1181.1181
Published: 2015
Journal Articles

PRMT5 Methyltransferase Activity Is Required to Sustain Adult Hematopoiesis

Fan LIU, PhD, Guoyan Cheng, PhD, Fabiana Perna, MD PhD, Xu Haiming, PhD, Pierre-Jacques Hamard, PhD, Luisa Luciani, PhD, Stephen Nimer, MD
Journal: Blood
Blood (2014) 124 (21): 4335.
https://doi.org/10.1182/blood.V124.21.4335.4335
Published: 2014