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Journal Articles

Tyrosine Phosphorylation of CARM1 Promotes Its Enzymatic Activity and Alters Its Target Specificity in Myeloid Neoplasms with Hyperactivated JAK2

Hidehiro Itonaga, Adnan K Mookhtiar, Sarah Greenblatt, Fan Liu, Concepcion Martinez, Renata Grozovsky, Daniel Bilbao, Masai Rains, Pierre-Jacques Hamard, Jun Sun, Afoma Umeano, Stephanie Duffort, Chuan Chen, Na Man, Gloria Mas Martin, Stephen Schürer, Stephen D Nimer

Blood (2022) 140 (Supplement 1): 3021–3022.

https://doi.org/10.1182/blood-2022-156887

Published: 2022

Journal Articles

Immune cells surveil aberrantly sialylated O -glycans on megakaryocytes to regulate platelet count

Melissa M. Lee-Sundlov, Robert T. Burns, Taylor O. Kim, Renata Grozovsky, Silvia Giannini, Leonardo Rivadeneyra, Yongwei Zheng, Simon H. Glabere, Walter H. A. Kahr, Reza Abdi, Jenny M. Despotovic, Demin Wang, Karin M. Hoffmeister

Blood (2021) 138 (23): 2408–2424.

https://doi.org/10.1182/blood.2020008238

Published: 2021

Includes: Multimedia, Supplemental data

Journal Articles

Plasmacytoid Dendritic Cells Surveil Megakaryocyte Sialic Acid to Regulate Thrombopoiesis

Melissa M. Lee-Sundlov, PhD, Robert Burns, PhD, Renata Grozovsky, PhD, Silvia Giannini, PhD, Leonardo Rivadeneyra, PhD, Yongwei Zheng, PhD, Simon Glabere, Walter H. Kahr, MDPhDFRCPC, Reza Abdi, Demin Wang, PhD, Karin M. Hoffmeister, MD

Blood (2020) 136 (Supplement 1): 12–13.

https://doi.org/10.1182/blood-2020-142737

Published: 2020

Journal Articles

Desialylation and Apoptosis Crosstalk to Modulate Platelet Clearance

Renata Grozovsky, PhD, Cameron Fraser, BS, Karin M. Hoffmeister, MD, Kristopher Sarosiek, PhD, Silvia Giannini, PhD

Blood (2019) 134 (Supplement_1): 1055.

https://doi.org/10.1182/blood-2019-122184

Published: 2019

Journal Articles

Sialic Acid Content on Platelet Surface Glycoproteins Modulates Thrombin-Induced Activation

Alexander Prete, Alexander Urtula, Renata Grozovsky, PhD

Blood (2018) 132 (Supplement 1): 3730.

https://doi.org/10.1182/blood-2018-99-119303

Published: 2018

Journal Articles

GPVI Intracellular Signaling Is Activated in Platelets from Patients with Essential Thrombocythemia

Gabriela S. Hobbs, MD, Vanessa Eldridge, MS, Richard M. Stone, MD, Martha Wadleigh, MD, David P. Steensma, MD, Gregory A. Abel, MD, Daniel J. DeAngelo, MD, Ann Mullally, MD, Renata Grozovsky, PhD

Blood (2017) 130 (Supplement 1): 1025.

https://doi.org/10.1182/blood.V130.Suppl_1.1025.1025

Published: 2017

Journal Articles

Effects of Platelet Circulatory Age on Platelet Function

Moritz Stolla, MD, Renata Grozovsky, PhD, Melissa M Lee-Sundlov, PhD, Herve Falet, PhD, Karin M. Hoffmeister, MD

Blood (2016) 128 (22): 413.

https://doi.org/10.1182/blood.V128.22.413.413

Published: 2016

Journal Articles

Bone Marrow Macrophage Galectin-3 Regulates Platelet Production through Recognition of O-Glycans on Megakaryocytes

Melissa M Lee-Sundlov, PhD, Renata Grozovsky, PhD, Silvia Giannini, PhD, Martina McGrath, MD, Haley E Ramsey, PhD MSc, Martha Sola-Visner, MD, Karin M. Hoffmeister, MD

Blood (2016) 128 (22): 409.

https://doi.org/10.1182/blood.V128.22.409.409

Published: 2016

Journal Articles

Recognition of Megakaryocyte-Specific T-Antigen By Macrophages Negatively Regulates Platelet Production in Bone Marrow

Melissa M. Lee-Sundlov, PhD, Renata Grozovsky, PhD, Silvia Giannini, PhD, Martina McGrath, MD, Haley Elizabeth Ramsey, PhD MSc, Reza Abdi, MD, Martha Sola-Visner, MD, Karin M. Hoffmeister, MD

Blood (2015) 126 (23): 420.

https://doi.org/10.1182/blood.V126.23.420.420

Published: 2015

Journal Articles

Regulating billions of blood platelets: glycans and beyond

Renata Grozovsky, Silvia Giannini, Hervé Falet, Karin M. Hoffmeister

Blood (2015) 126 (16): 1877–1884.

https://doi.org/10.1182/blood-2015-01-569129

Published: 2015

Journal Articles

Dynamin 2–dependent endocytosis is required for normal megakaryocyte development in mice

Markus Bender, Silvia Giannini, Renata Grozovsky, Terese Jönsson, Hilary Christensen, Fred G. Pluthero, Amy Ko, Ann Mullally, Walter H. A. Kahr, Karin M. Hoffmeister, Hervé Falet

Blood (2015) 125 (6): 1014–1024.

https://doi.org/10.1182/blood-2014-07-587857

Published: 2015

Journal Articles

Platelet Desialylation: A Novel Mechanism of Fc-Independent Platelet Clearance and a Potential Diagnostic Biomarker and Therapeutic Target in immune Thrombocytopenia

June Li, MSc, Dianne Evertdina van der Wal, PhD, Guangheng Zhu, MD, Miao Xu, MSc, MD, Issaka Yougbare, PhD, Li Ma, PhD, Brian Vadasz, BSc, Renata Grozovsky, PhD, Min Ruan, MD, Lingyan Zhu, MD, Qingshu Zeng, MD, Lili Tao, MD, Zhi-min Zhai, MD, Jun Peng, MD, Ming Hou, MD, Valery Leytin, PhD, John J. Freedman, MD, Karin M Hoffmeister, MD, Heyu Ni, MD PhD

Blood (2014) 124 (21): 467.

https://doi.org/10.1182/blood.V124.21.467.467

Published: 2014

Journal Articles

Dynamin 2-Dependent Endocytosis Regulates Megakaryopoiesis

Markus Bender, Silvia Giannini, Terese Jönsson, Renata Grozovsky, PhD, Hilary Christensen, Fred G Pluthero, Walter H Kahr, Karin M Hoffmeister, MD, Hervé Falet, PhD

Blood (2014) 124 (21): 339.

https://doi.org/10.1182/blood.V124.21.339.339

Published: 2014

Journal Articles

In Newborn Mice, Tpo Signaling Is Required for Normal Megakaryocyte Proliferation, Maturation, Platelet Formation, and Platelet Survival

Haley Ramsey, PhD, Francesca Ferrer-Marin, MD, Renata Grozovsky, PhD, Hoffmeister Karin, MD, Joseph E. Italiano, PhD, Zhongbo Hu, MD PhD, William B. Slayton, MD, Martha Sola-Visner, MD

Blood (2014) 124 (21): 572.

https://doi.org/10.1182/blood.V124.21.572.572

Published: 2014

Journal Articles

T-Antigen Expression Causes Macrothrombocytopenia and Extensive Hemophagocytosis in Mice Lacking the Sialyltransferase ST3Gal-I Specifically in Megakaryocytes

Renata Grozovsky, PhD, Silvia Giannini, Haley Ramsey, PhD, Martha Sola-Visner, MD, Karin M Hoffmeister, MD

Blood (2014) 124 (21): 94.

https://doi.org/10.1182/blood.V124.21.94.94

Published: 2014

Journal Articles

The Ashwell-Morell Receptor Regulates Hepatic Thrombopoietin Production Via JAK2-STAT3 Signaling in Vivo and in Vitro

Renata Grozovsky, PhD, Antonija Jurak Begonja, John H. Hartwig, Prof, Herve Falet, PhD, Karin M Hoffmeister, MD

Blood (2014) 124 (21): 2.

https://doi.org/10.1182/blood.V124.21.2.2

Published: 2014

Journal Articles

Platelets Regulate Thrombopoietin Production: The Missing Link

Karin M Hoffmeister, MD, Hervé Falet, PhD, Renata Grozovsky, PhD

Blood (2014) 124 (21): SCI-52.

https://doi.org/10.1182/blood.V124.21.SCI-52.SCI-52

Published: 2014

Journal Articles

Expansion of the neonatal platelet mass is achieved via an extension of platelet lifespan

Zhi-Jian Liu, Karin M. Hoffmeister, Zhongbo Hu, Donald E. Mager, Sihem Ait-Oudhia, Marlyse A. Debrincat, Irina Pleines, Emma C. Josefsson, Benjamin T. Kile, Joseph Italiano, Jr, Haley Ramsey, Renata Grozovsky, Peter Veng-Pedersen, Chaitanya Chavda, Martha Sola-Visner

Blood (2014) 123 (22): 3381–3389.

https://doi.org/10.1182/blood-2013-06-508200

Published: 2014

Includes: Supplemental data

Journal Articles

Sialic Acid Loss Regulates Platelet Survival and Integrity

Renata Grozovsky, PhD, Gerard Jansen, MD, PhD, MSC, Karin M. Hoffmeister, MD

Blood (2013) 122 (21): 3504.

https://doi.org/10.1182/blood.V122.21.3504.3504

Published: 2013

Journal Articles

The Human Platelet Glycome and Its Variations Among Healthy Volunteers and Storage

Renata Grozovsky, PhD, Qiyong Peter Liu, PhD, Andrew Hanneman, David J. Ashline, Hailong Zhang, Vernon Reinhold, Karin M. Hoffmeister, MD

Blood (2013) 122 (21): 2300.

https://doi.org/10.1182/blood.V122.21.2300.2300

Published: 2013

NARROW

Tyrosine Phosphorylation of CARM1 Promotes Its Enzymatic Activity and Alters Its Target Specificity in Myeloid Neoplasms with Hyperactivated JAK2

Immune cells surveil aberrantly sialylated O -glycans on megakaryocytes to regulate platelet count

Plasmacytoid Dendritic Cells Surveil Megakaryocyte Sialic Acid to Regulate Thrombopoiesis

Desialylation and Apoptosis Crosstalk to Modulate Platelet Clearance

Sialic Acid Content on Platelet Surface Glycoproteins Modulates Thrombin-Induced Activation

GPVI Intracellular Signaling Is Activated in Platelets from Patients with Essential Thrombocythemia

Effects of Platelet Circulatory Age on Platelet Function

Bone Marrow Macrophage Galectin-3 Regulates Platelet Production through Recognition of O-Glycans on Megakaryocytes

Recognition of Megakaryocyte-Specific T-Antigen By Macrophages Negatively Regulates Platelet Production in Bone Marrow

Regulating billions of blood platelets: glycans and beyond

Dynamin 2–dependent endocytosis is required for normal megakaryocyte development in mice

Platelet Desialylation: A Novel Mechanism of Fc-Independent Platelet Clearance and a Potential Diagnostic Biomarker and Therapeutic Target in immune Thrombocytopenia

Dynamin 2-Dependent Endocytosis Regulates Megakaryopoiesis

In Newborn Mice, Tpo Signaling Is Required for Normal Megakaryocyte Proliferation, Maturation, Platelet Formation, and Platelet Survival

T-Antigen Expression Causes Macrothrombocytopenia and Extensive Hemophagocytosis in Mice Lacking the Sialyltransferase ST3Gal-I Specifically in Megakaryocytes

The Ashwell-Morell Receptor Regulates Hepatic Thrombopoietin Production Via JAK2-STAT3 Signaling in Vivo and in Vitro

Platelets Regulate Thrombopoietin Production: The Missing Link

Expansion of the neonatal platelet mass is achieved via an extension of platelet lifespan

Sialic Acid Loss Regulates Platelet Survival and Integrity

The Human Platelet Glycome and Its Variations Among Healthy Volunteers and Storage

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American Society of Hematology

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ASH Publications

American Society of Hematology

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