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Journal Articles

Extrafollicular B cell expansion in COVID-19 patients with prothrombotic antibodies linked to inflammatory and Th1 signatures

Nathan Witman, Mei Yu, Yuqi Zhang, Kexin Gai, Yuhong Chen, Lu Zhou, Christine Nguyen, Wen Zhu, Yongwei Zheng, Shawn Jobe, Mary Beth Graham, Weiguo Cui, Demin Wang, Renren Wen

Blood (2025) 146 (Supplement 1): 1232.

https://doi.org/10.1182/blood-2025-1232

Published: 2025

Journal Articles

An update: Safety and efficacy of GPRC5D targeting CAR-T cell therapy in relapsed/refractory multiple myeloma patients

Shiqi Li, Yongwei Zheng, Zhongtao Yuan, Lin Liu, Yu Li, Xiaoping Li, Yingnian Chen, Qingying Zang, Lihua Zhang, Mengli Xu, Ping Yin, Lvzhe Chen, Guangchao Li, Wen Ding, Kaikai Zeng, Donghui Ma, Chunfu Li, Min Luo, Sanbin Wang

Blood (2025) 146 (Supplement 1): 5854.

https://doi.org/10.1182/blood-2025-5854

Published: 2025

Journal Articles

JMJD1C-mediated epigenetic control of HIT antibody production

Mei Yu, Yongguang Zhang, Yuhong Chen, Lu Zhou, Yongwei Zheng, David W Wang, Nan Zhu, Renren Wen, Demin Wang

Blood (2025) 146 (Supplement 1): 3110.

https://doi.org/10.1182/blood-2025-3110

Published: 2025

Journal Articles

Development of a novel CD19/BCMA dual CAR-T for autoimmune diseases

Yongwei Zheng, Lisen Luo, Wen Ding, Kaikai Zeng, Donghui Ma, Min Luo

Blood (2025) 146 (Supplement 1): 7639.

https://doi.org/10.1182/blood-2025-7639

Published: 2025

Journal Articles

Prothrombotic antibodies targeting the spike protein's receptor-binding domain in severe COVID-19

Blood (2025) 145 (6): 635–647.

https://doi.org/10.1182/blood.2024025010

Published: 2025

Includes: Supplemental data

Journal Articles

A Subset of Antibodies to the Spike Protein's Receptor-Binding Domain in Severe COVID-19 Activate Platelets

Wen Zhu, Yongwei Zheng, Mei Yu, Nathan Witman, Anand Pabmanabhan, Lisa Baumann Kreuziger, Gilbert C. White, Tongjun Gu, Alexander Fields, Lucy Kornblith, Richard H. Aster, Weiguo Cui, Shawn M. Jobe, Mary Beth Graham, Demin Wang, Renren Wen

Blood (2024) 144 (Supplement 1): 1229.

https://doi.org/10.1182/blood-2024-211524

Published: 2024

Journal Articles

Epigenetic Control of B Cell Autoimmunity By Jmjd1c

Yongguang Zhang, Mei Yu, Yongwei Zheng, Yuhong Chen, Jesus Izaguirre-Carbonell, Nan Zhu, Renren Wen, Demin Wang

Blood (2023) 142 (Supplement 1): 155.

https://doi.org/10.1182/blood-2023-182034

Published: 2023

Journal Articles

Arid1b Loss Impairs Hematopoietic Stem Cell Function in Normal Hematopoiesis

Olivia Arnold, Theresa Bluemn, Cary Stelloh, Yongwei Zheng, Demin Wang, Sridhar Rao, Nan Zhu

Blood (2023) 142 (Supplement 1): 5588.

https://doi.org/10.1182/blood-2023-186386

Published: 2023

Journal Articles

Gab3 Plays an Essential Role in CD8 + T-Cell Expansion through Regulating IL-2-Mediated Activation of PI3K/AKT/mTOR and Erk/FoxO Pathways

Guoping Fu, Yongwei Zheng, Gang Xin, Zhengqi Wang, Kevin D. Bunting, Weiguo Cui, Arthur Salomon, Renren Wen

Blood (2023) 142 (Supplement 1): 3931.

https://doi.org/10.1182/blood-2023-185077

Published: 2023

Journal Articles

MiR-9-1 Controls Osteoblastic Regulation of Lymphopoiesis

Yongguang Zhang, Yongwei Zheng, Yuhong Chen, Mei Yu, Karen-Sue Carlson, Renren Wen, Demin Wang

Blood (2023) 142 (Supplement 1): 1333.

https://doi.org/10.1182/blood-2023-181128

Published: 2023

Journal Articles

Cloned antibodies from patients with HIT provide new clues to HIT pathogenesis

Wen Zhu, Yongwei Zheng, Mei Yu, Yaling Wu, Jianhui Wei, Lu Zhou, Guoping Fu, Nicholas Schneider, Curtis Jones, Mehraboon Irani, Anand Padmanabhan, Richard Aster, Demin Wang, Renren Wen

Blood (2023) 141 (9): 1060–1069.

https://doi.org/10.1182/blood.2022017612

Published: 2023

Includes: Supplemental data

Journal Articles

Immune cells surveil aberrantly sialylated O -glycans on megakaryocytes to regulate platelet count

Melissa M. Lee-Sundlov, Robert T. Burns, Taylor O. Kim, Renata Grozovsky, Silvia Giannini, Leonardo Rivadeneyra, Yongwei Zheng, Simon H. Glabere, Walter H. A. Kahr, Reza Abdi, Jenny M. Despotovic, Demin Wang, Karin M. Hoffmeister

Blood (2021) 138 (23): 2408–2424.

https://doi.org/10.1182/blood.2020008238

Published: 2021

Includes: Multimedia, Supplemental data

Journal Articles

CARD19, a Novel Negative Regulator of B-Cell Tolerance

Yongwei Zheng, Mei Yu, Yuhong Chen, Liquan Xue, Wen Zhu, Guoping Fu, Robert Burns, Stephan Morris, Renren Wen, Demin Wang

Blood (2021) 138 (Supplement 1): 997.

https://doi.org/10.1182/blood-2021-149732

Published: 2021

Journal Articles

Polyreactivity and Somatic Hypermutation Analysis Reveals the Innate B Cell Origin of Human PF4/Heparin Reactive Antibodies

Wen Zhu, MBBS,MS, Lu Zhou, Ting Zhao, Yongwei Zheng, PhD, Mei Yu, PhD, Jianhui Wei, Anand Padmanabhan, M.B.B.S., PhD, Richard H. Aster, MD, Demin Wang, PhD, Renren Wen, PhD

Blood (2020) 136 (Supplement 1): 34–35.

https://doi.org/10.1182/blood-2020-138781

Published: 2020

Journal Articles

Plasmacytoid Dendritic Cells Surveil Megakaryocyte Sialic Acid to Regulate Thrombopoiesis

Melissa M. Lee-Sundlov, PhD, Robert Burns, PhD, Renata Grozovsky, PhD, Silvia Giannini, PhD, Leonardo Rivadeneyra, PhD, Yongwei Zheng, PhD, Simon Glabere, Walter H. Kahr, MDPhDFRCPC, Reza Abdi, Demin Wang, PhD, Karin M. Hoffmeister, MD

Blood (2020) 136 (Supplement 1): 12–13.

https://doi.org/10.1182/blood-2020-142737

Published: 2020

Journal Articles

Both Arid1b and Arid2 Are Tumor Suppressors in MLL-AF9 Leukemogenesis

Theresa Bluemn, Jesse Schmitz, Yongwei Zheng, PhD, Nan Zhu, PhD

Blood (2019) 134 (Supplement_1): 1248.

https://doi.org/10.1182/blood-2019-127123

Published: 2019

Journal Articles

Antibody Cloning Identifies Pathogenic and Non-Pathogenic Antibodies in Heparin-Induced Thrombocytopenia and Defines the Molecular Signatures That Differentiate the Two Types of Antibodies

Wen Zhu, Yongwei Zheng, PhD, Mei Yu, PhD, Yaling Wu, Jianhui Wei, Nicholas Schneider, Anand Padmanabhan, MD PhD, Richard H. Aster, MD, Demin Wang, PhD, Renren Wen, PhD

Blood (2019) 134 (Supplement_1): 439.

https://doi.org/10.1182/blood-2019-126097

Published: 2019

Journal Articles

Regulatory T Cells Control PF4/Heparin Antibody Production in Mice

Yongwei Zheng, Wen Zhu, Dipica Haribhai, PhD, Calvin B. Williams, PhD, Richard H. Aster, MD, Renren Wen, PhD, Demin Wang, PhD

Blood (2018) 132 (Supplement 1): 2542.

https://doi.org/10.1182/blood-2018-99-113049

Published: 2018

Journal Articles

Critical Role of Jumonji Domain of JMJD1C in AML Leukemogenesis

Jesus Izaguirre-Carbonell, PhD, Christiansen Luke, Robert Burns, PhD, Jesse Schmitz, Chenxuan Li, Rebekah Mokry, Theresa Bluemn, Yongwei Zheng, Demin Wang, PhD, Nan Zhu, PhD

Blood (2018) 132 (Supplement 1): 2599.

https://doi.org/10.1182/blood-2018-99-110463

Published: 2018

Journal Articles

Phospholipase Cgamma Pathway-Dependent mTOR Signaling Controls IL-7-Mediated Early B Cell Development

Mei Yu, PhD, Chen Yuhong, PhD, Hu Zeng, PhD, Yongwei Zheng, PhD, Guoping Fu, PhD, Wen Zhu, Ulrich Broeckel, MD, Praful Aggarwal, Amy Turner, Geoffrey A.M. Neale, PhD, Nan Zhu, PhD, Hongbo Chi, PhD, Renren Wen, PhD, Demin Wang, PhD

Blood (2017) 130 (Supplement 1): 620.

https://doi.org/10.1182/blood.V130.Suppl_1.620.620

Published: 2017

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Extrafollicular B cell expansion in COVID-19 patients with prothrombotic antibodies linked to inflammatory and Th1 signatures

An update: Safety and efficacy of GPRC5D targeting CAR-T cell therapy in relapsed/refractory multiple myeloma patients

JMJD1C-mediated epigenetic control of HIT antibody production

Development of a novel CD19/BCMA dual CAR-T for autoimmune diseases

Prothrombotic antibodies targeting the spike protein's receptor-binding domain in severe COVID-19

A Subset of Antibodies to the Spike Protein's Receptor-Binding Domain in Severe COVID-19 Activate Platelets

Epigenetic Control of B Cell Autoimmunity By Jmjd1c

Arid1b Loss Impairs Hematopoietic Stem Cell Function in Normal Hematopoiesis

Gab3 Plays an Essential Role in CD8 + T-Cell Expansion through Regulating IL-2-Mediated Activation of PI3K/AKT/mTOR and Erk/FoxO Pathways

MiR-9-1 Controls Osteoblastic Regulation of Lymphopoiesis

Cloned antibodies from patients with HIT provide new clues to HIT pathogenesis

Immune cells surveil aberrantly sialylated O -glycans on megakaryocytes to regulate platelet count

CARD19, a Novel Negative Regulator of B-Cell Tolerance

Polyreactivity and Somatic Hypermutation Analysis Reveals the Innate B Cell Origin of Human PF4/Heparin Reactive Antibodies

Plasmacytoid Dendritic Cells Surveil Megakaryocyte Sialic Acid to Regulate Thrombopoiesis

Both Arid1b and Arid2 Are Tumor Suppressors in MLL-AF9 Leukemogenesis

Antibody Cloning Identifies Pathogenic and Non-Pathogenic Antibodies in Heparin-Induced Thrombocytopenia and Defines the Molecular Signatures That Differentiate the Two Types of Antibodies

Regulatory T Cells Control PF4/Heparin Antibody Production in Mice

Critical Role of Jumonji Domain of JMJD1C in AML Leukemogenesis

Phospholipase Cgamma Pathway-Dependent mTOR Signaling Controls IL-7-Mediated Early B Cell Development

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