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Journal Articles

ELISA-Negative Platelet-Activating Anti-PF4 Antibodies Can Cause HIT and Monoclonal Gammopathy of Thrombotic Significance (MGTS)

Adam Kanack, Nelson Leung, Noah Splinter, Emily Mauch, Morayma Reyes Gil, Leben Tefera, Sakshi Jasra, Andrew Goodwin, Hadiyah Audil, Aneel Ashrani, Nathaniel L. Robinson, Ana I. Casanegra, Curtis Jones, Shannon Pechauer, Erin Yttre, Mindy Kohlhagen, Rachel Leger, David L Murray, Dong Chen, Rajiv K. Pruthi, Anand Pabmanabhan
Journal: Blood
Blood (2023) 142 (Supplement 1): 682.
https://doi.org/10.1182/blood-2023-181121
Published: 2023
Journal Articles

Cloned antibodies from patients with HIT provide new clues to HIT pathogenesis

Wen Zhu, Yongwei Zheng, Mei Yu, Yaling Wu, Jianhui Wei, Lu Zhou, Guoping Fu, Nicholas Schneider, Curtis Jones, Mehraboon Irani, Anand Padmanabhan, Richard Aster, Demin Wang, Renren Wen
Journal: Blood
Blood (2023) 141 (9): 1060–1069.
https://doi.org/10.1182/blood.2022017612
Published: 2023
Includes: Supplemental data
Journal Articles

A Thrombospondin-1 Release Assay (TRA) Coupled to PF4-Treated Cryopreserved Platelets for the Detection of Pathogenic HIT and VITT Antibodies

Adam Kanack, Curtis Jones, Bandana Singh, Gemlyn George, Mouhamed Yazan Abou-Ismail, David L. Green, Alison Grazioli, Rachel Leger, Nahla M. Heikal, Dong Chen, Rajiv K. Pruthi, Anand Padmanabhan
Journal: Blood
Blood (2021) 138 (Supplement 1): 2130.
https://doi.org/10.1182/blood-2021-152953
Published: 2021
Journal Articles

New Monoclonal Antibodies Reveal Distinct Specificities for Platelet Factor 4 Bound to Heparin Vs. Platelets: Implications for HIT Pathogenesis

Anand Padmanabhan, MD PhD, Shannon Pechauer, Curtis Jones, BS, Daniel Bougie, PhD, Richard H. Aster, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1144.
https://doi.org/10.1182/blood-2019-127169
Published: 2019
Journal Articles

The Platelet Factor-4 (PF4)-Dependent p-Selectin Expression Assay (PEA) Is Highly Accurate for the Detection of Pathogenic HIT Antibodies: Results of a 440-Sample Prospective Blinded Study

Deepti M. Warad, MD, Bethany T Samuelson Bannow, MD, Curtis Jones, BS, Shannon Pechauer, Brian R. Curtis, PhD, Daniel W. Bougie, PhD, Parisa R Khalighi, BS, Diane E. Grill, MS, Rachel Leger, BAE, Ruchika Sharma, MD, Dong Chen, MD PhD, Richard H. Aster, MD, David A. Garcia, MD, Anand Padmanabhan, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 416.
https://doi.org/10.1182/blood-2018-99-112475
Published: 2018
Journal Articles

Immunoglobulin G in Normal Plasma Inhibits HIT Antibody-Mediated Platelet Activation: Implications for Therapeutic Plasma Exchange Treatment in HIT

Curtis Jones, BS, Shannon Pechauer, Brian R. Curtis, PhDMT(ASCP), Daniel W. Bougie, PhD, Richard H. Aster, MD, Anand Padmanabhan, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2402.
https://doi.org/10.1182/blood.V130.Suppl_1.2402.2402
Published: 2017
Journal Articles

A New Assay for Platelet-Activating HIT Antibodies, the PEA, Is Specific, Reproducible and Relatively Independent of the Choice of Platelet Donor

Shannon Pechauer, Curtis Jones, BS, Daniel W. Bougie, PhD, Brian R. Curtis, PhDMT(ASCP), Richard H. Aster, MD, Anand Padmanabhan, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 458.
https://doi.org/10.1182/blood.V130.Suppl_1.458.458
Published: 2017
Journal Articles

A Novel PF4-Dependent Platelet Activation Assay Identifies Patients Likely to Have Heparin-Induced Thrombocytopenia/Thrombosis (HIT)

Anand Padmanabhan, MBBS, MA, PhD, Curtis Jones, Brian R Curtis, MS, MT(ASCP)SBB, Daniel W. Bougie, PhD, Mia Sullivan, Namrata Peswani, MD MBBS, Janice McFarland, MD, Daniel Eastwood, Demin Wang, PhD, Richard H. Aster, MD
Journal: Blood
Blood (2015) 126 (23): 764.
https://doi.org/10.1182/blood.V126.23.764.764
Published: 2015
Journal Articles

A Novel Assay For The Preferential Detection Of “Pathogenic” HIT Antibodies

Anand Padmanabhan, MBBS, MA, PhD, Curtis Jones, BS, Daniel W. Bougie, PhD, Brian R Curtis, MS, MT(ASCP)SBB, Janice McFarland, MD, Richard H. Aster, MD
Journal: Blood
Blood (2013) 122 (21): 1125.
https://doi.org/10.1182/blood.V122.21.1125.1125
Published: 2013