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Journal Articles

TAF1, the Largest Subunit of Tfiid, Is Dispensable for Adult Hematopoiesis

Fan Liu, Jingyin Yue, Francesco Tamiro, Jun Sun, Pradeepkumar Reddy Cingaram, Krystal Lisa Hossack, Concepcion Martinza Caja, Felipe Beckedorff, Ramin Shiekhattar, Stephen D. Nimer

Blood (2023) 142 (Supplement 1): 5584.

https://doi.org/10.1182/blood-2023-187166

Published: 2023

Journal Articles

Tyrosine Phosphorylation of CARM1 Promotes Its Enzymatic Activity and Alters Its Target Specificity in Myeloid Neoplasms with Hyperactivated JAK2

Hidehiro Itonaga, Adnan K Mookhtiar, Sarah Greenblatt, Fan Liu, Concepcion Martinez, Renata Grozovsky, Daniel Bilbao, Masai Rains, Pierre-Jacques Hamard, Jun Sun, Afoma Umeano, Stephanie Duffort, Chuan Chen, Na Man, Gloria Mas Martin, Stephen Schürer, Stephen D Nimer

Blood (2022) 140 (Supplement 1): 3021–3022.

https://doi.org/10.1182/blood-2022-156887

Published: 2022

Journal Articles

The NLRC4 Inflammasome Drives Myelodysplastic Syndrome By Linking Epigenetic Reprogramming and Innate Immune Signaling

Chuan Chen, Na Man, Francesco Tamiro, Krystal Hossack, Julio Poveda, Daniel Bilbao, Gloria Mas, Stephanie Duffort, Concepcion Martinez, Hidehiro Itonaga, Fan Liu, Jennifer R Chapman-Fredricks, Stephen D Nimer

Blood (2022) 140 (Supplement 1): 3009–3010.

https://doi.org/10.1182/blood-2022-160075

Published: 2022

Journal Articles

EP300 Suppresses Leukemia Development in Myelodysplastic Syndrome through Myb Repression

Na Man, Gloria Mas Martin, PhD, Daniel Karl, PhD, Jun Sun, PhD, Fan Liu, PhD, Miguel Torres-Martin, PhD, Hidehiro Itonaga, MD PhD, Concepcion Martinez, B.S., Shi Chen, Stephanie Duffort, Pierre-Jacques Hamard, PhD, Ye Xu, PhD, Luisa Cimmino, PhDBSc, Feng-Chun Yang, MD PhD, Philip A. Cole, MD PhD, Mingjiang Xu, MD PhD, Maria E. Figueroa, MD, Stephen Nimer, MD

Blood (2019) 134 (Supplement_1): 561.

https://doi.org/10.1182/blood-2019-130507

Published: 2019

Journal Articles

A Novel Hybrid Transplantation with Autologous Hematopoietic Stem Cells and Matched Unrelated Cord Blood Stem Cells Is Effecttive and Safe for Relapsed or Refractory Lymphoma: A Pilot Study

Blood (2019) 134 (Supplement_1): 5713.

https://doi.org/10.1182/blood-2019-129459

Published: 2019

Journal Articles

PRMT5 interacts with the BCL6 oncoprotein and is required for germinal center formation and lymphoma cell survival

Xiaoqing Lu, Tharu M. Fernando, Chen Lossos, Nevin Yusufova, Fan Liu, Lorena Fontán, Matthew Durant, Huimin Geng, Jacob Melnick, Yuan Luo, Francisco Vega, Vincent Moy, Giorgio Inghirami, Stephen Nimer, Ari M. Melnick, Izidore S. Lossos

Blood (2018) 132 (19): 2026–2039.

https://doi.org/10.1182/blood-2018-02-831438

Published: 2018

Includes: Supplemental data

Journal Articles

CARM1/PRMT4 As a Novel Therapeutic Target for AML

Sarah Greenblatt, PhD, Na Man, Pierre-Jacques Hamard, PhD, Concepcion Martinez, B.S., Ye Xu, PhD, Fan Liu, PhD, Justin M Watts, MD, Daniel G. Tenen, MD, Stephen D. Nimer, MD

Blood (2017) 130 (Supplement 1): 241.

https://doi.org/10.1182/blood.V130.Suppl_1.241.241

Published: 2017

Journal Articles

PRMT5 Regulates DNA Repair By Controlling the Alternative Splicing of Epigenetic Factors

Pierre-Jacques Hamard, PhD, Gabriel Emmanuel Santiago, Fan Liu, PhD, Sarah Greenblatt, PhD, Daniel Karl, PhD, Concepcion Martinez, B.S., Ramiro E Verdun, PhD, Stephen D. Nimer, MD

Blood (2017) 130 (Supplement 1): 1148.

https://doi.org/10.1182/blood.V130.Suppl_1.1148.1148

Published: 2017

Journal Articles

Caspase-3 controls AML1-ETO–driven leukemogenesis via autophagy modulation in a ULK1-dependent manner

Na Man, Yurong Tan, Xiao-Jian Sun, Fan Liu, Guoyan Cheng, Sarah M. Greenblatt, Camilo Martinez, Daniel L. Karl, Koji Ando, Ming Sun, Dan Hou, Bingyi Chen, Mingjiang Xu, Feng-Chun Yang, Zhu Chen, Saijuan Chen, Stephen D. Nimer, Lan Wang

Blood (2017) 129 (20): 2782–2792.

https://doi.org/10.1182/blood-2016-10-745034

Published: 2017

Includes: Supplemental data

Journal Articles

Caspase-3 Can Promote Acute Myeloid Leukemia Development By Regulation of Autophagy

Na Man, PhD, Yurong Tan, PhD, Fan Liu, PhD, Guoyan Cheng, PhD, Sarah Merin Greenblatt, PhD, Camilo Martinez, Xiao-Jian Sun, PhD, Stephen D. Nimer, MD, Lan Wang, PhD

Blood (2016) 128 (22): 2714.

https://doi.org/10.1182/blood.V128.22.2714.2714

Published: 2016

Journal Articles

The AML-Associated FLT3-ITD Kinase Regulates Histone Modifications and Cytokine Signaling, Via Effects on PRMT5

Koji Ando, MD PhD, Pierre-Jacques Hamard, PhD, Fan Liu, PhD, Concepcion Martinez, Yuguang Ban, PhD, Xi Chen, PhD, Stephen D. Nimer, MD

Blood (2016) 128 (22): 2696.

https://doi.org/10.1182/blood.V128.22.2696.2696

Published: 2016

Journal Articles

Differential role of Id1 in MLL-AF9–driven leukemia based on cell of origin

Na Man, Xiao-Jian Sun, Yurong Tan, Marta García-Cao, Fan Liu, Guoyan Cheng, Megan Hatlen, Haiming Xu, Ronit Shah, Nolan Chastain, Na Liu, Gang Huang, Yuan Zhou, Mengyao Sheng, Junhong Song, Feng-Chun Yang, Robert Benezra, Stephen D. Nimer, Lan Wang

Blood (2016) 127 (19): 2322–2326.

https://doi.org/10.1182/blood-2015-11-677708

Published: 2016

Includes: Supplemental data

Journal Articles

Prmt5 Negatively Regulates Erythropoiesis By Multiple Mechanisms, Including Controlling DNA Methyltransferase 3A Protein Levels

Pierre-Jacques Hamard, PhD, Luisa Luciani, PhD, Fan Liu, PhD, Guoyan Cheng, PhD, Megan A. Hatlen, PhD, Olga A Guryanova, MD, PhD, Xinyang Zhao, PhD, Ross L. Levine, MD, Stephen D. Nimer, MD

Blood (2015) 126 (23): 1181.

https://doi.org/10.1182/blood.V126.23.1181.1181

Published: 2015

Journal Articles

Regulation of AKT signaling by Id1 controls t(8;21) leukemia initiation and progression

Lan Wang, Na Man, Xiao-Jian Sun, Yurong Tan, Marta García-Cao, Fan Liu, Megan Hatlen, Haiming Xu, Gang Huang, Meredith Mattlin, Arpit Mehta, Evadnie Rampersaud, Robert Benezra, Stephen D. Nimer

Blood (2015) 126 (5): 640–650.

https://doi.org/10.1182/blood-2015-03-635532

Published: 2015

Includes: Supplemental data

Journal Articles

PRMT5 Methyltransferase Activity Is Required to Sustain Adult Hematopoiesis

Fan LIU, PhD, Guoyan Cheng, PhD, Fabiana Perna, MD PhD, Xu Haiming, PhD, Pierre-Jacques Hamard, PhD, Luisa Luciani, PhD, Stephen Nimer, MD

Blood (2014) 124 (21): 4335.

https://doi.org/10.1182/blood.V124.21.4335.4335

Published: 2014

Journal Articles

L3MBTL1: A Polycomb Protein At the Node of Crosstalk Between the BMP4 and Hippo Signaling Pathways in Erythropoiesis.

Fabiana Perna, MD, Ly P. Vu, Maria Themeli, MD, PhD, Ruben Hoya-Arias, PhD, Fan Liu, MD, PhD, Lan Wang, PhD, Nadia Gurvich, PhD, Todd Hricik, BS, Eirini P. Papapetrou, MD, PhD, Malcolm A.S. AS Moore, Ross L. Levine, Michel Sadelain, MD, PhD, Stephen Nimer, MD

Blood (2012) 120 (21): 2296.

https://doi.org/10.1182/blood.V120.21.2296.2296

Published: 2012

Journal Articles

Nuclear JAK2

Mark A. Dawson, Andrew J. Bannister, Lindsay Saunders, Omar-Abdel Wahab, Fan Liu, Stephen D. Nimer, Ross L. Levine, Berthold Göttgens, Tony Kouzarides, Anthony R. Green

Blood (2011) 118 (26): 6987–6988.

https://doi.org/10.1182/blood-2011-10-385278

Published: 2011

Journal Articles

JAK2 V617F, PRMT5, and GATA-1 Form a Regulatory Loop That Controls Autophagy Via Effects on ATG3 Gene Expression

Michael W Harr, Ph.D., Xinyang Zhao, Ph.D., Mary Klein, Fan Liu, Ph.D., Megan Hatlen, Stephen Nimer, M.D.

Blood (2011) 118 (21): 2822.

https://doi.org/10.1182/blood.V118.21.2822.2822

Published: 2011

Journal Articles

Methylation of RUNX1 by the Nuclear PRMT5/COPR5 Complex Regulates Its Cellular Location in Leukemia Cells,

Xinyang Zhao, Ph.D., Ly P. Vu, Fabiana Perna, MD, Fan Liu, MD, Hao Xu, Stephen Nimer

Blood (2011) 118 (21): 3403.

https://doi.org/10.1182/blood.V118.21.3403.3403

Published: 2011

Journal Articles

JAK2V617F-Mediated Phosphorylation of PRMT5 Down-Regulates Its Methyltransferase Activity and Promotes Myeloproliferation

Fan Liu, Xinyang Zhao, Fabiana Perna, Lan Wang, Priya Koppikar, Omar Abdel-Wahab, Ross L Levine, Hao Xue, Megan Hatlen, Silvia Menendez, Stephen D Nimer

Blood (2010) 116 (21): 794.

https://doi.org/10.1182/blood.V116.21.794.794

Published: 2010

NARROW

TAF1, the Largest Subunit of Tfiid, Is Dispensable for Adult Hematopoiesis

Tyrosine Phosphorylation of CARM1 Promotes Its Enzymatic Activity and Alters Its Target Specificity in Myeloid Neoplasms with Hyperactivated JAK2

The NLRC4 Inflammasome Drives Myelodysplastic Syndrome By Linking Epigenetic Reprogramming and Innate Immune Signaling

EP300 Suppresses Leukemia Development in Myelodysplastic Syndrome through Myb Repression

A Novel Hybrid Transplantation with Autologous Hematopoietic Stem Cells and Matched Unrelated Cord Blood Stem Cells Is Effecttive and Safe for Relapsed or Refractory Lymphoma: A Pilot Study

PRMT5 interacts with the BCL6 oncoprotein and is required for germinal center formation and lymphoma cell survival

CARM1/PRMT4 As a Novel Therapeutic Target for AML

PRMT5 Regulates DNA Repair By Controlling the Alternative Splicing of Epigenetic Factors

Caspase-3 controls AML1-ETO–driven leukemogenesis via autophagy modulation in a ULK1-dependent manner

Caspase-3 Can Promote Acute Myeloid Leukemia Development By Regulation of Autophagy

The AML-Associated FLT3-ITD Kinase Regulates Histone Modifications and Cytokine Signaling, Via Effects on PRMT5

Differential role of Id1 in MLL-AF9–driven leukemia based on cell of origin

Prmt5 Negatively Regulates Erythropoiesis By Multiple Mechanisms, Including Controlling DNA Methyltransferase 3A Protein Levels

Regulation of AKT signaling by Id1 controls t(8;21) leukemia initiation and progression

PRMT5 Methyltransferase Activity Is Required to Sustain Adult Hematopoiesis

L3MBTL1: A Polycomb Protein At the Node of Crosstalk Between the BMP4 and Hippo Signaling Pathways in Erythropoiesis.

Nuclear JAK2

JAK2 V617F, PRMT5, and GATA-1 Form a Regulatory Loop That Controls Autophagy Via Effects on ATG3 Gene Expression

Methylation of RUNX1 by the Nuclear PRMT5/COPR5 Complex Regulates Its Cellular Location in Leukemia Cells,

JAK2V617F-Mediated Phosphorylation of PRMT5 Down-Regulates Its Methyltransferase Activity and Promotes Myeloproliferation

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ASH Publications

American Society of Hematology

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ASH Publications

American Society of Hematology

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