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Journal Articles

Mutagenic DNA Lesions in Normal Hematopoietic Stem Cells Persist for Years Causing Distinct Patterns of Mutation

Blood (2024) 144 (Supplement 1): 2673.

https://doi.org/10.1182/blood-2024-208773

Published: 2024

Journal Articles

Adaptation to ex vivo culture reduces human hematopoietic stem cell activity independently of the cell cycle

Blood (2024) 144 (7): 729–741.

https://doi.org/10.1182/blood.2023021426

Published: 2024

Includes: Supplemental data

Journal Articles

Polygenic Germline Risk of Common Haematological Traits Drives Clonal Selection on JAK2 V617F and Development of Myeloproliferative Neoplasms

Jyoti Nangalia, Jing Guo, Klaudia Walter, Pedro Quiros, Muxin Gu, E Joanna Baxter, John Danesh, Emanuele Di Angelantonio, David Roberts, Paola Guglielmelli, Claire N Harrison, Anna L Godfrey, Anthony R Green, George Vassiliou, Dragana Vuckovic, Nicole Soranzo

Blood (2023) 142 (Supplement 1): 863.

https://doi.org/10.1182/blood-2023-189551

Published: 2023

Journal Articles

Iron homeostasis governs erythroid phenotype in polycythemia vera

Blood (2023) 141 (26): 3199–3214.

https://doi.org/10.1182/blood.2022016779

Published: 2023

Includes: Supplemental data

Journal Articles

STAT1 is essential for HSC function and maintains MHCII hi stem cells that resist myeloablation and neoplastic expansion

Blood (2022) 140 (14): 1592–1606.

https://doi.org/10.1182/blood.2021014009

Published: 2022

Includes: Supplemental data

Journal Articles

Clonal Dynamics of Normal Haematopoiesis with Human Ageing

Blood (2021) 138 (Supplement 1): 598.

https://doi.org/10.1182/blood-2021-150152

Published: 2021

Journal Articles

Changes in Clonal Architecture Inform MPN Disease Course in Advance of Phenotypic Manifestations

Joe S Lee, Nicholas Williams, Joanna E Baxter, Anna L Godfrey, Kate Milne, Karim Mane, David C Wedge, Peter J. Campbell, Anthony R Green, Jyoti Nangalia

Blood (2021) 138 (Supplement 1): 3590.

https://doi.org/10.1182/blood-2021-152436

Published: 2021

Journal Articles

Driver Mutation Acquisition in Utero and Childhood Followed By Lifelong Clonal Evolution Underlie Myeloproliferative Neoplasms

Nicholas Williams, PhD, Joe Lee, MBBS, Luiza Moore, PhD, Joanna E Baxter, PhD, James Hewinson, PhD, Kevin J Dawson, PhD, Andrew Menzies, MSc, Anna L Godfrey, PhD, Anthony R Green, PhDFRCPath FMedSci, Peter J Campbell, PhD, Jyoti Nangalia, MBBChir

Blood (2020) 136 (Supplement_2): LBA-1.

https://doi.org/10.1182/blood-2020-143813

Published: 2020

Journal Articles

Mutant CALR functions: gains and losses

Daniel Prins, Anthony R. Green

Blood (2020) 136 (1): 6–7.

https://doi.org/10.1182/blood.2020005805

Published: 2020

Journal Articles

Cohesin-dependent regulation of gene expression during differentiation is lost in cohesin-mutated myeloid malignancies

Daniel Sasca, Haiyang Yun, George Giotopoulos, Jakub Szybinski, Theo Evan, Nicola K. Wilson, Moritz Gerstung, Paolo Gallipoli, Anthony R. Green, Robert Hills, Nigel Russell, Cameron S. Osborne, Elli Papaemmanuil, Berthold Göttgens, Peter Campbell, Brian J. P. Huntly

Blood (2019) 134 (24): 2195–2208.

https://doi.org/10.1182/blood.2019001553

Published: 2019

Includes: Supplemental data

Journal Articles

Life History of Normal Human Lymphocytes Revealed By Somatic Mutations

Heather E Machado, PhD, Nina Friesgaard Øbro, Emily Mitchell, Megan Davies, Anthony R Green, Kourosh Saeb-Parsy, Daniel James Hodson, MD PhD, David Kent, PhD, Peter J Campbell

Blood (2019) 134 (Supplement_1): 1045.

https://doi.org/10.1182/blood-2019-128188

Published: 2019

Journal Articles

Clonal approaches to understanding the impact of mutations on hematologic disease development

Jyoti Nangalia, Emily Mitchell, Anthony R. Green

Blood (2019) 133 (13): 1436–1445.

https://doi.org/10.1182/blood-2018-11-835405

Published: 2019

Journal Articles

Single Cell RNA-Seq Characterises Pre-Leukemic Transformation Driven By CEBPA N321D in the Hoxb8-FL Cell Line

Moosa Qureshi, MBBS, MRCP, Fernando Calero-Nieto, Iwo Kucinski, Sarah Kinston, George Giotopoulos, Dean Pask, Rebecca Hannah, Evangelia Diamanti, Xiaonan Wang, Reiner Schulte, Chiara Cossetti, Anthony R Green, Brian J.P Huntly, Berthold Gottgens

Blood (2018) 132 (Supplement 1): 3887.

https://doi.org/10.1182/blood-2018-99-110626

Published: 2018

Journal Articles

Niche Heterogeneity Impacts Evolution of Myeloproliferative Neoplasms Driven By the Same Oncogenic Pathway

Blood (2018) 132 (Supplement 1): 98.

https://doi.org/10.1182/blood-2018-99-113495

Published: 2018

Journal Articles

Single-cell approaches identify the molecular network driving malignant hematopoietic stem cell self-renewal

Mairi S. Shepherd, Juan Li, Nicola K. Wilson, Caroline A. Oedekoven, Jiangbing Li, Miriam Belmonte, Juergen Fink, Janine C. M. Prick, Dean C. Pask, Tina L. Hamilton, Dirk Loeffler, Anjana Rao, Timm Schröder, Berthold Göttgens, Anthony R. Green, David G. Kent

Blood (2018) 132 (8): 791–803.

https://doi.org/10.1182/blood-2017-12-821066

Published: 2018

Includes: Supplemental data

Journal Articles

Mutant calreticulin knockin mice develop thrombocytosis and myelofibrosis without a stem cell self-renewal advantage

Juan Li, Daniel Prins, Hyun Jung Park, Jacob Grinfeld, Carlos Gonzalez-Arias, Stephen Loughran, Oliver M. Dovey, Thorsten Klampfl, Cavan Bennett, Tina L. Hamilton, Dean C. Pask, Rachel Sneade, Matthew Williams, Juliet Aungier, Cedric Ghevaert, George S. Vassiliou, David G. Kent, Anthony R. Green

Blood (2018) 131 (6): 649–661.

https://doi.org/10.1182/blood-2017-09-806356

Published: 2018

Includes: Supplemental data

Journal Articles

Ruxolitinib-Induced Defects in DNA Repair Cause Sensitivity to PARP Inhibitors in Myeloproliferative Neoplasms

Margaret Nieborowska-Skorska, Silvia Maifrede, Yashodhara Dasgupta, Katherine Sullivan, Bac Viet Le, Martyna Solecka, Lucia Kubovcakova, Morgan Nawrocki, Martin Kirschner, MD, Huaqing Zhao, Josef T. Prchal, MD, Katarzyna Piwocka, Alison R. Moliterno, MD, Steffen Koschmieder, Anthony R Green, PhD FRCP, FRCPath, FMedSci, Radek C. Skoda, MD, Tomasz Skorski

Blood (2017) 130 (Supplement 1): 2938.

https://doi.org/10.1182/blood.V130.Suppl_1.2938.2938

Published: 2017

Journal Articles

Personalized Prognostic Predictions for Patients with Myeloproliferative Neoplasms through Integration of Comprehensive Genomic and Clinical Information

Blood (2017) 130 (Supplement 1): 491.

https://doi.org/10.1182/blood.V130.Suppl_1.491.491

Published: 2017

Journal Articles

A Knowledge-Based Approach for Clinical Annotation of Oncogenic Variants to Support Patient-Tailored Diagnosis in Myeloid Disease

Blood (2017) 130 (Supplement 1): 1414.

https://doi.org/10.1182/blood.V130.Suppl_1.1414.1414

Published: 2017

Journal Articles

Hydroxycarbamide Plus Aspirin Vs Aspirin Alone in Intermediate Risk Essential Thrombocythemia: Results of the PT-1 International, Prospective, Randomized Clinical Trial

Anna L. Godfrey, BMBCh, PhD MRCP, FRCPath, Peter J Campbell, MD PhD, Cathy MacLean, BSc, MSc, MBA, Georgina Buck, BSc, MSc, Clare L. East, BSc, Julia Cook, BSc, Julie Temple, BSc, Bridget S. Wilkins, MD FRCPath, Keith Wheatley, DPhil, Jyoti Nangalia, MBBChir, MA, MRCP, FRCPath, PhD, Jacob Grinfeld, MBChB, BSc, MRCP, FRCPath, Mary Frances Frances McMullin, MB,Bch BAO, MD FRCPath, Cecily Forsyth, MB BS, Jean-Jacques Kiladjian, MD PhD, Anthony R. Green, FRCP, FRCPath, FMed Sci, Claire N. Harrison, BMBCh, DM, FRCP, FRCPath

Blood (2017) 130 (Supplement 1): 319.

https://doi.org/10.1182/blood.V130.Suppl_1.319.319

Published: 2017

NARROW

Mutagenic DNA Lesions in Normal Hematopoietic Stem Cells Persist for Years Causing Distinct Patterns of Mutation

Adaptation to ex vivo culture reduces human hematopoietic stem cell activity independently of the cell cycle

Polygenic Germline Risk of Common Haematological Traits Drives Clonal Selection on JAK2 V617F and Development of Myeloproliferative Neoplasms

Iron homeostasis governs erythroid phenotype in polycythemia vera

STAT1 is essential for HSC function and maintains MHCII hi stem cells that resist myeloablation and neoplastic expansion

Clonal Dynamics of Normal Haematopoiesis with Human Ageing

Changes in Clonal Architecture Inform MPN Disease Course in Advance of Phenotypic Manifestations

Driver Mutation Acquisition in Utero and Childhood Followed By Lifelong Clonal Evolution Underlie Myeloproliferative Neoplasms

Mutant CALR functions: gains and losses

Cohesin-dependent regulation of gene expression during differentiation is lost in cohesin-mutated myeloid malignancies

Life History of Normal Human Lymphocytes Revealed By Somatic Mutations

Clonal approaches to understanding the impact of mutations on hematologic disease development

Single Cell RNA-Seq Characterises Pre-Leukemic Transformation Driven By CEBPA N321D in the Hoxb8-FL Cell Line

Niche Heterogeneity Impacts Evolution of Myeloproliferative Neoplasms Driven By the Same Oncogenic Pathway

Single-cell approaches identify the molecular network driving malignant hematopoietic stem cell self-renewal

Mutant calreticulin knockin mice develop thrombocytosis and myelofibrosis without a stem cell self-renewal advantage

Ruxolitinib-Induced Defects in DNA Repair Cause Sensitivity to PARP Inhibitors in Myeloproliferative Neoplasms

Personalized Prognostic Predictions for Patients with Myeloproliferative Neoplasms through Integration of Comprehensive Genomic and Clinical Information

A Knowledge-Based Approach for Clinical Annotation of Oncogenic Variants to Support Patient-Tailored Diagnosis in Myeloid Disease

Hydroxycarbamide Plus Aspirin Vs Aspirin Alone in Intermediate Risk Essential Thrombocythemia: Results of the PT-1 International, Prospective, Randomized Clinical Trial

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American Society of Hematology

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ASH Publications

American Society of Hematology

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