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Journal Articles

STAT1 is essential for HSC function and maintains MHCII hi stem cells that resist myeloablation and neoplastic expansion

Blood (2022) 140 (14): 1592–1606.

https://doi.org/10.1182/blood.2021014009

Published: 2022

Includes: Supplemental data

Journal Articles

CRLF3 plays a key role in the final stage of platelet genesis and is a potential therapeutic target for thrombocythemia

Blood (2022) 139 (14): 2227–2239.

https://doi.org/10.1182/blood.2021013113

Published: 2022

Includes: Multimedia, Supplemental data

Journal Articles

Microvesicles, but not platelets, bud off from mouse bone marrow megakaryocytes

Joseph E. Italiano, Markus Bender, Glenn Merrill-Skoloff, Cedric Ghevaert, Bernhard Nieswandt, Robert Flaumenhaft

Blood (2021) 138 (20): 1998–2001.

https://doi.org/10.1182/blood.2021012496

Published: 2021

Includes: Supplemental data

Journal Articles

Aging of Bone Marrow Microenvironment Promotes Myeloid Bias of Hematopoietic Progenitors and Is a Target in Age-Related Myeloproliferative Neoplasms

Blood (2018) 132 (Supplement 1): 3842.

https://doi.org/10.1182/blood-2018-99-116015

Published: 2018

Journal Articles

Mutant calreticulin knockin mice develop thrombocytosis and myelofibrosis without a stem cell self-renewal advantage

Juan Li, Daniel Prins, Hyun Jung Park, Jacob Grinfeld, Carlos Gonzalez-Arias, Stephen Loughran, Oliver M. Dovey, Thorsten Klampfl, Cavan Bennett, Tina L. Hamilton, Dean C. Pask, Rachel Sneade, Matthew Williams, Juliet Aungier, Cedric Ghevaert, George S. Vassiliou, David G. Kent, Anthony R. Green

Blood (2018) 131 (6): 649–661.

https://doi.org/10.1182/blood-2017-09-806356

Published: 2018

Includes: Supplemental data

Journal Articles

A high-throughput sequencing test for diagnosing inherited bleeding, thrombotic, and platelet disorders

Ilenia Simeoni, Jonathan C. Stephens, Fengyuan Hu, Sri V. V. Deevi, Karyn Megy, Tadbir K. Bariana, Claire Lentaigne, Sol Schulman, Suthesh Sivapalaratnam, Minka J. A. Vries, Sarah K. Westbury, Daniel Greene, Sofia Papadia, Marie-Christine Alessi, Antony P. Attwood, Matthias Ballmaier, Gareth Baynam, Emilse Bermejo, Marta Bertoli, Paul F. Bray, Loredana Bury, Marco Cattaneo, Peter Collins, Louise C. Daugherty, Rémi Favier, Deborah L. French, Bruce Furie, Michael Gattens, Manuela Germeshausen, Cedric Ghevaert, Anne C. Goodeve, Jose A. Guerrero, Daniel J. Hampshire, Daniel P. Hart, Johan W. M. Heemskerk, Yvonne M. C. Henskens, Marian Hill, Nancy Hogg, Jennifer D. Jolley, Walter H. Kahr, Anne M. Kelly, Ron Kerr, Myrto Kostadima, Shinji Kunishima, Michele P. Lambert, Ri Liesner, José A. López, Rutendo P. Mapeta, Mary Mathias, Carolyn M. Millar, Amit Nathwani, Marguerite Neerman-Arbez, Alan T. Nurden, Paquita Nurden, Maha Othman, Kathelijne Peerlinck, David J. Perry, Pawan Poudel, Pieter Reitsma, Matthew T. Rondina, Peter A. Smethurst, William Stevenson, Artur Szkotak, Salih Tuna, Christel van Geet, Deborah Whitehorn, David A. Wilcox, Bin Zhang, Shoshana Revel-Vilk, Paolo Gresele, Daniel B. Bellissimo, Christopher J. Penkett, Michael A. Laffan, Andrew D. Mumford, Augusto Rendon, Keith Gomez, Kathleen Freson, Willem H. Ouwehand, Ernest Turro

Blood (2016) 127 (23): 2791–2803.

https://doi.org/10.1182/blood-2015-12-688267

Published: 2016

Includes: Supplemental data

Journal Articles

Circular RNA enrichment in platelets is a signature of transcriptome degradation

Abd A. Alhasan, Osagie G. Izuogu, Haya H. Al-Balool, Jannetta S. Steyn, Amanda Evans, Maria Colzani, Cedric Ghevaert, Joanne C. Mountford, Lamin Marenah, David J. Elliott, Mauro Santibanez-Koref, Michael S. Jackson

Blood (2016) 127 (9): e1–e11.

https://doi.org/10.1182/blood-2015-06-649434

Published: 2016

Includes: Supplemental data

Journal Articles

Suppression of in vitro megakaryopoiesis by maternal sera containing anti-HPA-1a antibodies

Zhi-Jian Liu, James B. Bussel, Madhavi Lakkaraja, Francisca Ferrer-Marin, Cedric Ghevaert, Henry A. Feldman, Janice G. McFarland, Chaitanya Chavda, Martha Sola-Visner

Blood (2015) 126 (10): 1234–1236.

https://doi.org/10.1182/blood-2014-11-611020

Published: 2015

Includes: Supplemental data

Journal Articles

Gray platelet syndrome: proinflammatory megakaryocytes and α-granule loss cause myelofibrosis and confer metastasis resistance in mice

Jose A. Guerrero, Cavan Bennett, Louise van der Weyden, Harriet McKinney, Melody Chin, Paquita Nurden, Zoe McIntyre, Emma L. Cambridge, Jeanne Estabel, Hannah Wardle-Jones, Anneliese O. Speak, Wendy N. Erber, Augusto Rendon, Willem H. Ouwehand, Cedric Ghevaert

Blood (2014) 124 (24): 3624–3635.

https://doi.org/10.1182/blood-2014-04-566760

Published: 2014

Includes: Supplemental data

Journal Articles

JAK2V617F homozygosity drives a phenotypic switch in myeloproliferative neoplasms, but is insufficient to sustain disease

Juan Li, David G. Kent, Anna L. Godfrey, Harriet Manning, Jyoti Nangalia, Athar Aziz, Edwin Chen, Kourosh Saeb-Parsy, Juergen Fink, Rachel Sneade, Tina L. Hamilton, Dean C. Pask, Yvonne Silber, Xiaodong Zhao, Cedric Ghevaert, Pentao Liu, Anthony R. Green

Blood (2014) 123 (20): 3139–3151.

https://doi.org/10.1182/blood-2013-06-510222

Published: 2014

Includes: Supplemental data

Journal Articles

JAK2V617F leads to intrinsic changes in platelet formation and reactivity in a knock-in mouse model of essential thrombocythemia

Catherine M. Hobbs, Harriet Manning, Cavan Bennett, Louella Vasquez, Sonia Severin, Lauren Brain, Alexandra Mazharian, Jose A. Guerrero, Juan Li, Nicole Soranzo, Anthony R. Green, Steve P. Watson, Cedric Ghevaert

Blood (2013) 122 (23): 3787–3797.

https://doi.org/10.1182/blood-2013-06-501452

Published: 2013

Includes: Supplemental data

Journal Articles

In Vitro Production Of Megakaryocytes and Platelets From Human Induced Pluripotent Cells By GMP Compatible Methods

Thomas Moreau, PhD, Maria Colzani, Meera Arumugam, PhD, Amanda Evans, Marloes Renee Tijssen, PhD, Matthew Trotter, PhD, Willem H Ouwehand, Roger Pedersen, MD PhD, Cedric Ghevaert, MD PhD

Blood (2013) 122 (21): 2401.

https://doi.org/10.1182/blood.V122.21.2401.2401

Published: 2013

Journal Articles

Recombinant HPA-1a antibody therapy for treatment of fetomaternal alloimmune thrombocytopenia: proof of principle in human volunteers

Cedric Ghevaert, Nina Herbert, Louise Hawkins, Nicola Grehan, Philip Cookson, Steve F. Garner, Abigail Crisp-Hihn, Paul Lloyd-Evans, Amanda Evans, Kottekkattu Balan, Willem H. Ouwehand, Kathryn L. Armour, Mike R. Clark, Lorna M. Williamson

Blood (2013) 122 (3): 313–320.

https://doi.org/10.1182/blood-2013-02-481887

Published: 2013

Includes: Supplemental data

Journal Articles

Dasatinib enhances megakaryocyte differentiation but inhibits platelet formation

Alexandra Mazharian, Cedric Ghevaert, Lin Zhang, Steffen Massberg, Steve P. Watson

Blood (2011) 117 (19): 5198–5206.

https://doi.org/10.1182/blood-2010-12-326850

Published: 2011

Includes: Supplemental data

Journal Articles

JAK2 V617F impairs hematopoietic stem cell function in a conditional knock-in mouse model of JAK2 V617F–positive essential thrombocythemia

Juan Li, Dominik Spensberger, Jong Sook Ahn, Shubha Anand, Philip A. Beer, Cedric Ghevaert, Edwin Chen, Ariel Forrai, Linda M. Scott, Rita Ferreira, Peter J. Campbell, Steve P. Watson, Pentao Liu, Wendy N. Erber, Brian J. P. Huntly, Katrin Ottersbach, Anthony R. Green

Blood (2010) 116 (9): 1528–1538.

https://doi.org/10.1182/blood-2009-12-259747

Published: 2010

Includes: Supplemental data

Journal Articles

Recombinant Human HPA-1A Antibodies for Treatment of Fetomaternal Alloimmune Thrombocytopenia (FMAIT): Proof of Principle in An in Vivo Murine Model and Human Volunteer Studies

Cedric Ghevaert, David A. Wilcox, PhD, Juan Fang, Kathryn Armour, Mike R Clark, Willem H. Ouwehand, Lorna M Williamson

Blood (2008) 112 (11): 85.

https://doi.org/10.1182/blood.V112.11.85.85

Published: 2008

Journal Articles

A nonsynonymous SNP in the ITGB3 gene disrupts the conserved membrane-proximal cytoplasmic salt bridge in the α IIb β 3 integrin and cosegregates dominantly with abnormal proplatelet formation and macrothrombocytopenia

Cedric Ghevaert, Alexandre Salsmann, Nicholas A. Watkins, Elisabeth Schaffner-Reckinger, Angela Rankin, Stephen F. Garner, Jonathan Stephens, Graham A. Smith, Najet Debili, William Vainchenker, Philip G. de Groot, James A. Huntington, Mike Laffan, Nelly Kieffer, Willem H. Ouwehand

Blood (2008) 111 (7): 3407–3414.

https://doi.org/10.1182/blood-2007-09-112615

Published: 2008

Includes: Supplemental data

Journal Articles

Recombinant Mini-β3 Integrin Fragments for the Detection of HPA-1 Antibodies.

Prachi Stafford, BSc, MRes, Cedric Ghevaert, MD. MRCP. MRCPath, Kate Campbell, Graham Smith, Lorna Williamson, BSc, MD, FRCP, FRCPath, Nicholas A. Watkins, BSc, PhD, Willem H. Ouwehand, MD. PhD. FRCPath

Blood (2005) 106 (11): 218.

https://doi.org/10.1182/blood.V106.11.218.218

Published: 2005

NARROW

STAT1 is essential for HSC function and maintains MHCII hi stem cells that resist myeloablation and neoplastic expansion

CRLF3 plays a key role in the final stage of platelet genesis and is a potential therapeutic target for thrombocythemia

Microvesicles, but not platelets, bud off from mouse bone marrow megakaryocytes

Aging of Bone Marrow Microenvironment Promotes Myeloid Bias of Hematopoietic Progenitors and Is a Target in Age-Related Myeloproliferative Neoplasms

Mutant calreticulin knockin mice develop thrombocytosis and myelofibrosis without a stem cell self-renewal advantage

A high-throughput sequencing test for diagnosing inherited bleeding, thrombotic, and platelet disorders

Circular RNA enrichment in platelets is a signature of transcriptome degradation

Suppression of in vitro megakaryopoiesis by maternal sera containing anti-HPA-1a antibodies

Gray platelet syndrome: proinflammatory megakaryocytes and α-granule loss cause myelofibrosis and confer metastasis resistance in mice

JAK2V617F homozygosity drives a phenotypic switch in myeloproliferative neoplasms, but is insufficient to sustain disease

JAK2V617F leads to intrinsic changes in platelet formation and reactivity in a knock-in mouse model of essential thrombocythemia

In Vitro Production Of Megakaryocytes and Platelets From Human Induced Pluripotent Cells By GMP Compatible Methods

Recombinant HPA-1a antibody therapy for treatment of fetomaternal alloimmune thrombocytopenia: proof of principle in human volunteers

Dasatinib enhances megakaryocyte differentiation but inhibits platelet formation

JAK2 V617F impairs hematopoietic stem cell function in a conditional knock-in mouse model of JAK2 V617F–positive essential thrombocythemia

Recombinant Human HPA-1A Antibodies for Treatment of Fetomaternal Alloimmune Thrombocytopenia (FMAIT): Proof of Principle in An in Vivo Murine Model and Human Volunteer Studies

A nonsynonymous SNP in the ITGB3 gene disrupts the conserved membrane-proximal cytoplasmic salt bridge in the α IIb β 3 integrin and cosegregates dominantly with abnormal proplatelet formation and macrothrombocytopenia

Recombinant Mini-β3 Integrin Fragments for the Detection of HPA-1 Antibodies.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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