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Journal Articles

Canonical Wnt signaling in megakaryocytes regulates proplatelet formation

Iain C. Macaulay, Jonathan N. Thon, Marloes R. Tijssen, Brian M. Steele, Bryan T. MacDonald, Gerardene Meade, Philippa Burns, Augusto Rendon, Vishal Salunkhe, Ronan P. Murphy, Cavan Bennett, Nicholas A. Watkins, Xi He, Desmond J. Fitzgerald, Joseph E. Italiano, Jr, Patricia B. Maguire

Blood (2013) 121 (1): 188–196.

https://doi.org/10.1182/blood-2012-03-416875

Published: 2013

Includes: Supplemental data

Journal Articles

Transcription profiling in human platelets reveals LRRFIP1 as a novel protein regulating platelet function

Blood (2010) 116 (22): 4646–4656.

https://doi.org/10.1182/blood-2010-04-280925

Published: 2010

Includes: Supplemental data

Journal Articles

A functional genomics approach reveals novel quantitative trait loci associated with platelet signaling pathways

Blood (2009) 114 (7): 1405–1416.

https://doi.org/10.1182/blood-2009-02-202614

Published: 2009

Includes: Supplemental data

Journal Articles

A HaemAtlas: characterizing gene expression in differentiated human blood cells

Blood (2009) 113 (19): e1–e9.

https://doi.org/10.1182/blood-2008-06-162958

Published: 2009

Includes: Supplemental data

Journal Articles

Functional genomics in zebrafish permits rapid characterization of novel platelet membrane proteins

Marie N. O'Connor, Isabelle I. Salles, Ana Cvejic, Nicholas A. Watkins, Adam Walker, Stephen F. Garner, Chris I. Jones, Iain C. Macaulay, Michael Steward, Jaap-Jan Zwaginga, Sarah L. Bray, Frank Dudbridge, Bernard de Bono, Alison H. Goodall, Hans Deckmyn, Derek L. Stemple, Willem H. Ouwehand

Blood (2009) 113 (19): 4754–4762.

https://doi.org/10.1182/blood-2008-06-162693

Published: 2009

Includes: Multimedia, Supplemental data

Journal Articles

A novel variant on chromosome 7q22.3 associated with mean platelet volume, counts, and function

Blood (2009) 113 (16): 3831–3837.

https://doi.org/10.1182/blood-2008-10-184234

Published: 2009

Includes: Supplemental data

Journal Articles

Functional Genomics in Zebrafish Permits Rapid Characterization of Novel Platelet Membrane Proteins

Isabelle I Salles, Marie N O’Connor, Nicholas A. Watkins, Adam Walker, Stephen F Garner, Chris I Jones, Iain Macauley, Michael Steward, Jaap Jan Zwaginga, Sarah L Bray, Ana Cvejic, Frank Dudbridge, Bernard de Bono, Hans Deckmyn, Derek L. Stemple, Willem Ouwehand, MD, PhD

Blood (2008) 112 (11): 2860.

https://doi.org/10.1182/blood.V112.11.2860.2860

Published: 2008

Journal Articles

The HaemAtlas: Characterising Gene Expression in Differentiated Human Blood Cells

Blood (2008) 112 (11): 2453.

https://doi.org/10.1182/blood.V112.11.2453.2453

Published: 2008

Journal Articles

A Common Single Nucleotide Polymorphism in the Chromosome 7q22.3 Region, Which Is Frequently Deleted in Myeloid Malignancies, Is Associated with Mean Platelet Volume and Platelet Function in Healthy Individuals

Blood (2008) 112 (11): 86.

https://doi.org/10.1182/blood.V112.11.86.86

Published: 2008

Journal Articles

A nonsynonymous SNP in the ITGB3 gene disrupts the conserved membrane-proximal cytoplasmic salt bridge in the α IIb β 3 integrin and cosegregates dominantly with abnormal proplatelet formation and macrothrombocytopenia

Cedric Ghevaert, Alexandre Salsmann, Nicholas A. Watkins, Elisabeth Schaffner-Reckinger, Angela Rankin, Stephen F. Garner, Jonathan Stephens, Graham A. Smith, Najet Debili, William Vainchenker, Philip G. de Groot, James A. Huntington, Mike Laffan, Nelly Kieffer, Willem H. Ouwehand

Blood (2008) 111 (7): 3407–3414.

https://doi.org/10.1182/blood-2007-09-112615

Published: 2008

Includes: Supplemental data

Journal Articles

The novel inhibitory receptor G6B is expressed on the surface of platelets and attenuates platelet function in vitro

Stephen A. Newland, Iain C. Macaulay, Andres R. Floto, Edwin C. de Vet, Willem H. Ouwehand, Nicholas A. Watkins, Paul A. Lyons, Duncan R. Campbell

Blood (2007) 109 (11): 4806–4809.

https://doi.org/10.1182/blood-2006-09-047449

Published: 2007

Includes: Supplemental data

Journal Articles

Comparative gene expression profiling of in vitro differentiated megakaryocytes and erythroblasts identifies novel activatory and inhibitory platelet membrane proteins

Iain C. Macaulay, Marloes R. Tijssen, Daphne C. Thijssen-Timmer, Arief Gusnanto, Michael Steward, Philippa Burns, Cordelia F. Langford, Peter D. Ellis, Frank Dudbridge, Jaap-Jan Zwaginga, Nicholas A. Watkins, C. Ellen van der Schoot, Willem H. Ouwehand

Blood (2006) 109 (8): 3260–3269.

https://doi.org/10.1182/blood-2006-07-036269

Published: 2006

Includes: Supplemental data

Journal Articles

Recombinant Mini-β3 Integrin Fragments for the Detection of HPA-1 Antibodies.

Prachi Stafford, BSc, MRes, Cedric Ghevaert, MD. MRCP. MRCPath, Kate Campbell, Graham Smith, Lorna Williamson, BSc, MD, FRCP, FRCPath, Nicholas A. Watkins, BSc, PhD, Willem H. Ouwehand, MD. PhD. FRCPath

Blood (2005) 106 (11): 218.

https://doi.org/10.1182/blood.V106.11.218.218

Published: 2005

Journal Articles

Identification of the primary collagen-binding surface on human glycoprotein VI by site-directed mutagenesis and by a blocking phage antibody

Peter A. Smethurst, Lotta Joutsi-Korhonen, Marie N. O'Connor, Erica Wilson, Nicola S. Jennings, Stephen F. Garner, Yanjun Zhang, C. Graham Knight, Timothy R. Dafforn, Ashley Buckle, Martin J. W. IJsseldijk, Philip G. de Groot, Nicholas A. Watkins, Richard W. Farndale, Willem H. Ouwehand

Blood (2004) 103 (3): 903–911.

https://doi.org/10.1182/blood-2003-01-0308

Published: 2004

Journal Articles

Single-chain antibody fragments derived from a human synthetic phage-display library bind thrombospondin and inhibit sickle cell adhesion

Nicholas A. Watkins, Lily M. Du, J. Paul Scott, Willem H. Ouwehand, Cheryl A. Hillery

Blood (2003) 102 (2): 718–724.

https://doi.org/10.1182/blood-2002-11-3497

Published: 2003

Journal Articles

The low-frequency allele of the platelet collagen signaling receptor glycoprotein VI is associated with reduced functional responses and expression

Lotta Joutsi-Korhonen, Peter A. Smethurst, Angela Rankin, Elaine Gray, Martin IJsseldijk, Catherine M. Onley, Nicholas A. Watkins, Lorna M. Williamson, Alison H. Goodall, Philip G. de Groot, Richard W. Farndale, Willem H. Ouwehand

Blood (2003) 101 (11): 4372–4379.

https://doi.org/10.1182/blood-2002-08-2591

Published: 2003

Journal Articles

HPA-1a phenotype–genotype discrepancy reveals a naturally occurring Arg93Gln substitution in the platelet β3 integrin that disrupts the HPA-1a epitope

Nicholas A. Watkins, Elisabeth Schaffner-Reckinger, David L. Allen, Graham J. Howkins, Nicolaas H. C. Brons, Graham A. Smith, Paul Metcalfe, Michael F. Murphy, Nelly Kieffer, Willem H. Ouwehand

Blood (2002) 99 (5): 1833–1839.

https://doi.org/10.1182/blood.V99.5.1833

Published: 2002

NARROW

Canonical Wnt signaling in megakaryocytes regulates proplatelet formation

Transcription profiling in human platelets reveals LRRFIP1 as a novel protein regulating platelet function

A functional genomics approach reveals novel quantitative trait loci associated with platelet signaling pathways

A HaemAtlas: characterizing gene expression in differentiated human blood cells

Functional genomics in zebrafish permits rapid characterization of novel platelet membrane proteins

A novel variant on chromosome 7q22.3 associated with mean platelet volume, counts, and function

Functional Genomics in Zebrafish Permits Rapid Characterization of Novel Platelet Membrane Proteins

The HaemAtlas: Characterising Gene Expression in Differentiated Human Blood Cells

A Common Single Nucleotide Polymorphism in the Chromosome 7q22.3 Region, Which Is Frequently Deleted in Myeloid Malignancies, Is Associated with Mean Platelet Volume and Platelet Function in Healthy Individuals

A nonsynonymous SNP in the ITGB3 gene disrupts the conserved membrane-proximal cytoplasmic salt bridge in the α IIb β 3 integrin and cosegregates dominantly with abnormal proplatelet formation and macrothrombocytopenia

The novel inhibitory receptor G6B is expressed on the surface of platelets and attenuates platelet function in vitro

Comparative gene expression profiling of in vitro differentiated megakaryocytes and erythroblasts identifies novel activatory and inhibitory platelet membrane proteins

Recombinant Mini-β3 Integrin Fragments for the Detection of HPA-1 Antibodies.

Identification of the primary collagen-binding surface on human glycoprotein VI by site-directed mutagenesis and by a blocking phage antibody

Single-chain antibody fragments derived from a human synthetic phage-display library bind thrombospondin and inhibit sickle cell adhesion

The low-frequency allele of the platelet collagen signaling receptor glycoprotein VI is associated with reduced functional responses and expression

HPA-1a phenotype–genotype discrepancy reveals a naturally occurring Arg93Gln substitution in the platelet β3 integrin that disrupts the HPA-1a epitope

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American Society of Hematology

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American Society of Hematology

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