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Marc F. Hoylaerts
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Journal Articles

A novel mechanism regulating human platelet activation by MMP-2–mediated PAR1 biased signaling

Manuela Sebastiano, Stefania Momi, Emanuela Falcinelli, Loredana Bury, Marc F. Hoylaerts, Paolo Gresele
Journal: Blood
Blood (2017) 129 (7): 883–895.
https://doi.org/10.1182/blood-2016-06-724245
Published: 2017
Includes: Supplemental data
Journal Articles

Allele-specific DNA methylation reinforces PEAR1 enhancer activity

Benedetta Izzi, Mariaelena Pistoni, Katrien Cludts, Pinar Akkor, Diether Lambrechts, Catherine Verfaillie, Peter Verhamme, Kathleen Freson, Marc F. Hoylaerts
Journal: Blood
Blood (2016) 128 (7): 1003–1012.
https://doi.org/10.1182/blood-2015-11-682153
Published: 2016
Includes: Supplemental data
Journal Articles

Animal Models of Aging Research

Marc F. Hoylaerts, PhD
Journal: Blood
Blood (2015) 126 (23): SCI-4.
https://doi.org/10.1182/blood.V126.23.SCI-4.SCI-4
Published: 2015
Journal Articles

Adhesion of Staphylococcus aureus to the vessel wall under flow is mediated by von Willebrand factor–binding protein

Jorien Claes, Thomas Vanassche, Marijke Peetermans, Laurens Liesenborghs, Christophe Vandenbriele, Karen Vanhoorelbeke, Dominique Missiakas, Olaf Schneewind, Marc F. Hoylaerts, Ruth Heying, Peter Verhamme
Journal: Blood
Blood (2014) 124 (10): 1669–1676.
https://doi.org/10.1182/blood-2014-02-558890
Published: 2014
Includes: Multimedia, Supplemental data
Journal Articles

Increased Thrombin Generation and Fibrin Formation In Premature Aging BMAL1 Deficient Mice

Marisa Ninivaggi, Hilde Kelchtermans, PhD, Marijke Kuipers, PhD, Bianca Hemmeryckx, PhD, Johan Heemskerk, PhD, Theo Lindhout, PhD, Marc F. Hoylaerts, PhD, Bas De Laat, PhD
Journal: Blood
Blood (2013) 122 (21): 3575.
https://doi.org/10.1182/blood.V122.21.3575.3575
Published: 2013
Journal Articles

PEAR1 attenuates megakaryopoiesis via control of the PI3K/PTEN pathway

Alexandre Kauskot, Christophe Vandenbriele, Sophie Louwette, Rik Gijsbers, Thomas Tousseyn, Kathleen Freson, Peter Verhamme, Marc F. Hoylaerts
Journal: Blood
Blood (2013) 121 (26): 5208–5217.
https://doi.org/10.1182/blood-2012-10-462887
Published: 2013
Includes: Supplemental data
Journal Articles

A novel mechanism of sustained platelet αIIbβ3 activation via PEAR1

Alexandre Kauskot, Michela Di Michele, Serena Loyen, Kathleen Freson, Peter Verhamme, Marc F. Hoylaerts
Journal: Blood
Blood (2012) 119 (17): 4056–4065.
https://doi.org/10.1182/blood-2011-11-392787
Published: 2012
Includes: Supplemental data
Journal Articles

Towards An Improvement of the Coagulation Imbalance in Sickle Cell Disease After Hematopoietic Stem Cell Transplantation: A Preliminary Study

Denis F Noubouossie, MD, Jan Emmerechts, MD, France Debaugnies, PharmD, Phu-Quoc Le, MD, Laurence Rozen, PharmD, Marc F. Hoylaerts, PhD, Anne Demulder, MD, PHD, Alina Ferster, MD
Journal: Blood
Blood (2011) 118 (21): 4840.
https://doi.org/10.1182/blood.V118.21.4840.4840
Published: 2011
Journal Articles

Evaluation of the profibrinolytic properties of an anti-TAFI monoclonal antibody in a mouse thromboembolism model

Ellen Vercauteren, Jan Emmerechts, Miet Peeters, Marc F. Hoylaerts, Paul J. Declerck, Ann Gils
Journal: Blood
Blood (2011) 117 (17): 4615–4622.
https://doi.org/10.1182/blood-2010-08-303677
Published: 2011
Includes: Supplemental data
Journal Articles

To the heart of the APS puzzle

Marc F. Hoylaerts
Journal: Blood
Blood (2010) 116 (16): 2867–2869.
https://doi.org/10.1182/blood-2010-07-297572
Published: 2010
Journal Articles

Platelet JNK1 is involved in secretion and thrombus formation

Frédéric Adam, Alexandre Kauskot, Paquita Nurden, Eric Sulpice, Marc F. Hoylaerts, Roger J. Davis, Jean-Philippe Rosa, Marijke Bryckaert
Journal: Blood
Blood (2010) 115 (20): 4083–4092.
https://doi.org/10.1182/blood-2009-07-233932
Published: 2010
Journal Articles

Thrombotic risk assessment in the antiphospholipid syndrome requires more than the quantification of lupus anticoagulants

Katrien Devreese, Kathelijne Peerlinck, Marc F. Hoylaerts
Journal: Blood
Blood (2010) 115 (4): 870–878.
https://doi.org/10.1182/blood-2009-09-244426
Published: 2010
Includes: Supplemental data
Journal Articles

A functional genomics approach reveals novel quantitative trait loci associated with platelet signaling pathways

Chris I. Jones, Sarah Bray, Stephen F. Garner, Jonathan Stephens, Bernard de Bono, Will G. J. Angenent, David Bentley, Philippa Burns, Alison Coffey, Panos Deloukas, Mark Earthrowl, Richard W. Farndale, Marc F. Hoylaerts, Kerstin Koch, Angela Rankin, Catherine M. Rice, Jane Rogers, Nilesh J. Samani, Michael Steward, Adam Walker, Nicholas A. Watkins, Jan-Willem Akkerman, Frank Dudbridge, Alison H. Goodall, Willem H. Ouwehand
Journal: Blood
Blood (2009) 114 (7): 1405–1416.
https://doi.org/10.1182/blood-2009-02-202614
Published: 2009
Includes: Supplemental data
Journal Articles

Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes

Marc Tjwa, Lola Bellido-Martin, Yuan Lin, Esther Lutgens, Stéphane Plaisance, Françoise Bono, Nathalie Delesque-Touchard, Caroline Hervé, Rute Moura, An D. Billiau, Cristina Aparicio, Marcel Levi, Mat Daemen, Mieke Dewerchin, Florea Lupu, Jef Arnout, Jean-Marc Herbert, Mark Waer, Pablo García de Frutos, Björn Dahlbäck, Peter Carmeliet, Marc F. Hoylaerts, Lieve Moons
Journal: Blood
Blood (2008) 111 (8): 4096–4105.
https://doi.org/10.1182/blood-2007-05-089565
Published: 2008
Includes: Supplemental data
Journal Articles

PACAP and its receptor VPAC1 regulate megakaryocyte maturation: therapeutic implications

Kathleen Freson, Karen Peeters, Rita De Vos, Christine Wittevrongel, Chantal Thys, Marc F. Hoylaerts, Jos Vermylen, Chris Van Geet
Journal: Blood
Blood (2008) 111 (4): 1885–1893.
https://doi.org/10.1182/blood-2007-06-098558
Published: 2008
Includes: Supplemental data
Journal Articles

Inhibition of VPAC1 Signaling Raises Platelet Numbers after Myelosuppressive Therapy and in GATA1 Congenital Thrombocytopenia.

Karen Peeters, Kathleen Freson, PhD, Christine Wittevrongel, Chantal Thys, Jean-Marie Stassen, PhD, Marc F. Hoylaerts, PhD, Chris Van Geet, MD PhD
Journal: Blood
Blood (2007) 110 (11): 1264.
https://doi.org/10.1182/blood.V110.11.1264.1264
Published: 2007
Journal Articles

Activation of α IIb β 3 is a sufficient but also an imperative prerequisite for activation of α 2 β 1 on platelets

Gerlinde R. Van de Walle, Anne Schoolmeester, Brecht F. Iserbyt, Judith M. E. M. Cosemans, Johan W. M. Heemskerk, Marc F. Hoylaerts, Alan Nurden, Karen Vanhoorelbeke, Hans Deckmyn
Journal: Blood
Blood (2006) 109 (2): 595–602.
https://doi.org/10.1182/blood-2005-11-011775
Published: 2006
Journal Articles

Thrombospondin-1 controls vascular platelet recruitment and thrombus adherence in mice by protecting (sub)endothelial VWF from cleavage by ADAMTS13

Arnaud Bonnefoy, Kim Daenens, Hendrik B. Feys, Rita De Vos, Petra Vandervoort, Jos Vermylen, Jack Lawler, Marc F. Hoylaerts
Journal: Blood
Blood (2006) 107 (3): 955–964.
https://doi.org/10.1182/blood-2004-12-4856
Published: 2006
Journal Articles

VPAC1 Receptor-Mediated Regulation of Megakaryopoiesis.

Kathleen Freson, PhD, Chantal Thys, Christine Wittevrongel, Rita De Vos, PhD, Jos Vermylen, PhD, MD, Marc F. Hoylaerts, PhD, MD, Chris Van Geet, PhD, MD
Journal: Blood
Blood (2004) 104 (11): 735.
https://doi.org/10.1182/blood.V104.11.735.735
Published: 2004
Journal Articles

Monoclonal antibody IAC-1 is specific for activated α 2 β 1 and binds to amino acids 199 to 201 of the integrin α 2 I-domain

Anne Schoolmeester, Karen Vanhoorelbeke, Shinya Katsutani, Hilde Depraetere, Hendrik B. Feys, Johan M. W. Heemskerk, Marc F. Hoylaerts, Hans Deckmyn
Journal: Blood
Blood (2004) 104 (2): 390–396.
https://doi.org/10.1182/blood-2003-12-4224
Published: 2004