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Peter Carmeliet
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Journal Articles

Prolyl Hydroxylase 3 (Phd3) Is a Therapeutic Target in Isocitrate Dehydrogenase 1 (IDH1) Mutated Acute Myeloid Leukemia

Anuhar Chaturvedi, PhD, Michelle Maria Araujo Cruz, PhD, Ramya Goparaju, PhD, Razif Gabdoulline, Renate Schottmann, Kerstin Görlich, Arnold Kloos, Felicitas Thol, MD, Robert Geffers, PhD, Dimitrios Mougiakakos, Peter Carmeliet, MD PhD, Arnold Ganser, MD, Michael Heuser, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 759.
https://doi.org/10.1182/blood-2018-99-110425
Published: 2018
Journal Articles

Mutations in succinate dehydrogenase B ( SDHB ) enhance neutrophil survival independent of HIF-1α expression

Robert Jones, Kate E. McDonald, Joseph A. Willson, Bart Ghesquière, David Sammut, Eleni Daniel, Alison J. Harris, Amy Lewis, A. A. Roger Thompson, Rebecca S. Dickinson, Tracie Plant, Fiona Murphy, Pranvera Sadiku, Brian G. Keevil, Peter Carmeliet, Moira K. B. Whyte, John Newell-Price, Sarah R. Walmsley
Journal: Blood
Blood (2016) 127 (21): 2641–2644.
https://doi.org/10.1182/blood-2016-02-696922
Published: 2016
Includes: Supplemental data
Journal Articles

BGB324 Inhibits BCR-ABL TKI-Resistant Chronic Myeloid Leukemia

Isabel Ben Batalla, PhD, Robert Erdmann, PhD, Heather Jørgensen, PhD, Rebecca Mitchell, Thomas Ernst, MD, Gunhild von Amsberg, MD, Philippe Schafhausen, MD, Stephen Rankin, MD, Richard E. Clark, Prof MD, Steffen Koschmieder, MD, Alexander Schultze, MD, Subir Mitra, MD, Peter Vandenberghe, Prof MD PhD, Tim H. Brümmendorf, Prof MD, Peter Carmeliet, Prof MD PhD, Gudmundur Helgason, PhD, Andreas Hochhaus, MD, Klaus Pantel, Prof MD PhD, Carsten Bokemeyer, MD, Tessa L Holyoake, Prof PhD, Sonja Loges, MDPhD
Journal: Blood
Blood (2015) 126 (23): 1569.
https://doi.org/10.1182/blood.V126.23.1569.1569
Published: 2015
Journal Articles

Placenta Growth Factor Links the IL-13 Response and the Leukotriene Pathway to Augment Airway Hyper-Responsiveness

Marthe-Sandrine Eiymo Mwa Mpollo, PhD, Eric Brandt, PhD, Shiva Kumar Shanmukhappa, DVM, PhD, Paritha Arumugam, PhD, Swati Tiwari, Anastacia Loberg, Tilat Rizvi, PhD, Mark Lindsey, Bart Jonckx, PhD, Peter Carmeliet, Prof MD PhD, Vijay Kalra, Timothy Lecras, PhD, Nancy Ratner, PhD, Marsha wills-Karp, PhD, Gurjit Khurana hershey, MD PhD, Punam Malik, MD
Journal: Blood
Blood (2015) 126 (23): 977.
https://doi.org/10.1182/blood.V126.23.977.977
Published: 2015
Journal Articles

BGB324 Represents an Axl and BCR-ABL1 Inhibitor with Activity in the T315I Mutant

Robert Erdmann, PhDMSc, Heather Jorgensen, PhD, Isabel Ben-Batalla, PhD, Nils Kruse, PhD, David Micklem, PhD, Gunhild von Amsberg, MD, Philippe Schafhausen, MD, Alexander Schultze, MD MSc, Mark Wroblewski, MSc, Mascha Binder, Miguel Cubas-Cordova, MSc, Tobias Hadlich, MD, Melanie Janning, MD MSc, Stefanie Sawall, Victoria Gensch, Elaine K Allan, Leena Mukherjee, PhD, Heather Morrison, BSc, Jennifer Cassells, Nicolaus Kroeger, MD, James Lorens, MD, Richard E. Clark, MD, Steffen Koschmieder, MD, Peter Vandenberghe, MD PhD, Tim H. Brümmendorf, MD, Andreas Hochhaus, MD, Peter Carmeliet, MD PhD, Tessa L. Holyoake, MD PhD, Klaus Pantel, MD PhD, Carsten Bokemeyer, MD, Sonja Loges, MD PhD
Journal: Blood
Blood (2014) 124 (21): 4512.
https://doi.org/10.1182/blood.V124.21.4512.4512
Published: 2014
Journal Articles

Airway Hyper-Responsiveness Associated With Sickle Cell Disease Is Mediated By Placenta Growth Factor

Marthe-Sandrine Eiymo Mwa Mpollo, M.Sc., Mingyan Yang, MD, Anastacia Loberg, Tilat Rizvi, Ph.D., Michael Wourms, M.Sc., Lanxi Song, Katie Burke, Nancy Ratner, Ph.D., Peter Carmeliet, MD, PhD, Timothy LeCras, Ph.D., Marsha Wills-Karp, Ph.D., Punam Malik, MD
Journal: Blood
Blood (2013) 122 (21): 185.
https://doi.org/10.1182/blood.V122.21.185.185
Published: 2013
Journal Articles

Axl Represents a Therapeutic Target In T315I-Mutated and WT Chronic Myeloid Leukemia

Robert Erdmann, PhD MSc, Heather Jorgensen, PhD, Alexander Schultze, MD, MSc, Gunhild von Amsberg, MD, Isabel Ben-Battala, PhD, MSc, Mark Wroblewski, MSc, Miguel Cubas Cordova, MSc, Stefanie Sawall, Victoria Witzke, Elaine K Allan, Leena Mukherjee, PhD, Heather Morrison, Jennifer Cassels, Philippe Schafhausen, MD, Nicolaus Kroeger, MD, James Lorens, MD, Richard E. Clark, MBBS, MD, FRCP, FRCPath, Peter Vandenberghe, MD, PhD, Tim H. Brümmendorf, MD, Andreas Hochhaus, MD, Peter Carmeliet, MD, PhD, Klaus Pantel, MD, PhD, Carsten Bokemeyer, MD, Tessa L. Holyoake, PhD, FRCP, FRCPath, Sonja Loges, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 1469.
https://doi.org/10.1182/blood.V122.21.1469.1469
Published: 2013
Journal Articles

Axl, a prognostic and therapeutic target in acute myeloid leukemia mediates paracrine crosstalk of leukemia cells with bone marrow stroma

Isabel Ben-Batalla, Alexander Schultze, Mark Wroblewski, Robert Erdmann, Michael Heuser, Jonas S. Waizenegger, Kristoffer Riecken, Mascha Binder, Denis Schewe, Stefanie Sawall, Victoria Witzke, Miguel Cubas-Cordova, Melanie Janning, Jasmin Wellbrock, Boris Fehse, Christian Hagel, Jürgen Krauter, Arnold Ganser, James B. Lorens, Walter Fiedler, Peter Carmeliet, Klaus Pantel, Carsten Bokemeyer, Sonja Loges
Journal: Blood
Blood (2013) 122 (14): 2443–2452.
https://doi.org/10.1182/blood-2013-03-491431
Published: 2013
Includes: Supplemental data
Journal Articles

Matrix metalloproteinase-2 governs lymphatic vessel formation as an interstitial collagenase

Benoit Detry, Charlotte Erpicum, Jenny Paupert, Silvia Blacher, Catherine Maillard, Françoise Bruyère, Hélène Pendeville, Thibault Remacle, Vincent Lambert, Cédric Balsat, Sandra Ormenese, Françoise Lamaye, Els Janssens, Lieve Moons, Didier Cataldo, Frédéric Kridelka, Peter Carmeliet, Marc Thiry, Jean-Michel Foidart, Ingrid Struman, Agnès Noel
Journal: Blood
Blood (2012) 119 (21): 5048–5056.
https://doi.org/10.1182/blood-2011-12-400267
Published: 2012
Includes: Multimedia, Supplemental data
Journal Articles

Hypoxic induction of vascular endothelial growth factor regulates murine hematopoietic stem cell function in the low-oxygenic niche

Matilda Rehn, André Olsson, Kristian Reckzeh, Eva Diffner, Peter Carmeliet, Göran Landberg, Jörg Cammenga
Journal: Blood
Blood (2011) 118 (6): 1534–1543.
https://doi.org/10.1182/blood-2011-01-332890
Published: 2011
Includes: Supplemental data
Journal Articles

Role of synectin in lymphatic development in zebrafish and frogs

Karlien Hermans, Filip Claes, Wouter Vandevelde, Wei Zheng, Ilse Geudens, Fabrizio Orsenigo, Frederik De Smet, Evisa Gjini, Kristof Anthonis, Bin Ren, Dontcho Kerjaschki, Monica Autiero, Annelii Ny, Michael Simons, Mieke Dewerchin, Stefan Schulte-Merker, Elisabetta Dejana, Kari Alitalo, Peter Carmeliet
Journal: Blood
Blood (2010) 116 (17): 3356–3366.
https://doi.org/10.1182/blood-2009-11-254557
Published: 2010
Includes: Supplemental data
Journal Articles

Gas6 deficiency in recipient mice of allogeneic transplantation alleviates hepatic graft-versus-host disease

Laurent Burnier, François Saller, Linda Kadi, Anne C. Brisset, Rocco Sugamele, Lucie Baudino, Françoise Bono, Jean-Marc Herbert, Peter Carmeliet, Marc Schapira, Shozo Izui, Anne Angelillo-Scherrer
Journal: Blood
Blood (2010) 115 (16): 3390–3397.
https://doi.org/10.1182/blood-2009-02-206920
Published: 2010
Journal Articles

Malignant cells fuel tumor growth by educating infiltrating leukocytes to produce the mitogen Gas6

Sonja Loges, Thomas Schmidt, Marc Tjwa, Katie van Geyte, Dirk Lievens, Esther Lutgens, Davy Vanhoutte, Delphine Borgel, Stephane Plaisance, Marc Hoylaerts, Aernout Luttun, Mieke Dewerchin, Bart Jonckx, Peter Carmeliet
Journal: Blood
Blood (2010) 115 (11): 2264–2273.
https://doi.org/10.1182/blood-2009-06-228684
Published: 2010
Includes: Supplemental data
Journal Articles

Placental Growth Factor: a Novel, Stromal-Derived Target in Human CML.

Sonja Loges, M.D., Ph.D, Thomas Schmidt, M.D., Christa Maes, Ph.D., Bart Jonckx, Maria Kleppe, Kim De Keersmaecker, Ph.D., Marc Tjwa, M.D., Ph.D., Thomas Schenk, M.D., Karolien Anne Beel, Christiane DeWolf-Peeters, M.D., Geert Carmeliet, M.D., Ph.D., Jan Cools, PhD, Richard E Clark, M.D., Peter Vandenberghe, MD, PhD, Tim H Brummendorf, M.D., Tessa Holyoake, M.D., Andreas Hochhaus, MD, Peter Carmeliet, M.D., Ph.D.
Journal: Blood
Blood (2009) 114 (22): 42.
https://doi.org/10.1182/blood.V114.22.42.42
Published: 2009
Journal Articles

The Role of gas6 in Venous Thrombosis In Vivo.

Richard Robins, Peter Carmeliet, M.D., Ph.D., Mark Blostein, MDCM
Journal: Blood
Blood (2009) 114 (22): 3057.
https://doi.org/10.1182/blood.V114.22.3057.3057
Published: 2009
Journal Articles

Antibiotics may impair hematopoietic recovery after cytotoxic myeloablation

Marc Tjwa, Lieve Moons, Catherine Verfaillie, Peter Carmeliet
Journal: Blood
Blood (2009) 113 (7): 1608–1609.
https://doi.org/10.1182/blood-2008-10-185694
Published: 2009
Journal Articles

Evaluation of the Role of PlGF and the Therapeutic Potential of Anti-PlGF in BCR/ABL+ Leukemia.

Sonja Loges, M.D., Ph.D, Thomas Schmidt, M.D., Maria Kleppe, Kim De Keersmaecker, Ph.D., Marc Tjwa, M.D., Ph.D., Christa Maes, Ph.D., Christiane DeWolf-Peeters, M.D., Ph.D., Geert Carmeliet, M.D., Ph.D., Jan Cools, Ph.D., Jean-Marie Stassen, Ph.D., Peter Carmeliet, M.D., Ph.D.
Journal: Blood
Blood (2008) 112 (11): 1094.
https://doi.org/10.1182/blood.V112.11.1094.1094
Published: 2008
Journal Articles

Disruption of GAS6-MER Pathway Leads to Defects in Physiological Clearance of Expelled Nuclei from Erythroblasts by Bone Marrow Macrophages

Linda Kadi, Laurent Burnier, Rocco Sugamele, Peter Carmeliet, Greg Lemke, H. Shelton Earp, III, Glenn K. Matsushima, Marc Schapira, Anne Angelillo-Scherrer
Journal: Blood
Blood (2008) 112 (11): 499.
https://doi.org/10.1182/blood.V112.11.499.499
Published: 2008
Journal Articles

Plasmin therapy enhances mobilization of HPCs after G-CSF

Brief Report
Marc Tjwa, Stefan Janssens, Peter Carmeliet
Journal: Blood
Blood (2008) 112 (10): 4048–4050.
https://doi.org/10.1182/blood-2008-07-166587
Published: 2008
Includes: Supplemental data
Journal Articles

Role of VEGF-D and VEGFR-3 in developmental lymphangiogenesis, a chemicogenetic study in Xenopus tadpoles

Annelii Ny, Marta Koch, Wouter Vandevelde, Martin Schneider, Christian Fischer, Antonio Diez-Juan, Elke Neven, Ilse Geudens, Sunit Maity, Lieve Moons, Stéphane Plaisance, Diether Lambrechts, Peter Carmeliet, Mieke Dewerchin
Journal: Blood
Blood (2008) 112 (5): 1740–1749.
https://doi.org/10.1182/blood-2007-08-106302
Published: 2008
Includes: Supplemental data