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Denis Schewe
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Journal Articles

HEM-ismart: An international proof-of-concept therapeutic stratification trial of molecular anomalies in relapsed or refractory hematological malignancies in children

Free
Andrej Lissat, Francisco Bautista, Olli Lohi, Uri Ilan, Judith Boer, Monique Den Boer, Cornelia Eckert, Anne Elsinghorst, Ellis van Liempt, Britta Vormoor, Birgit Burkhardt, Jean Pierre Bourquin, Marie-Emilie Dourthe, Martha Grootenhuis, Frederick van Delft, Alwin Huitema, Shai Izraeli, Franco Locatelli, Marion Mateos, Denis Schewe, Arend von Stackelberg, Sarah Tasian, David Teachey, Harm Van Tinteren, C. Zwaan
Journal: Blood
Blood (2025) 146 (Supplement 1): 1582.
https://doi.org/10.1182/blood-2025-1582
Published: 2025
Journal Articles

The long non-coding RNA WT1-AS controls differentiation programs and leukemic cell fate in AML

Free
Silvia Schäfer, Pascal Fichtel, Silke Brilloff, Sandra Küchler, Elahe Rahimian, Vida Kufrin, Ekaterina Longvinova, Claudia Ball, Hanno Glimm, Denis Schewe, Malte Von Bonin, Martin Bornhäuser, Alexander Wurm, Marius Bill
Journal: Blood
Blood (2025) 146 (Supplement 1): 5022.
https://doi.org/10.1182/blood-2025-5022
Published: 2025
Journal Articles

Epigenetic regulator genes direct lineage switching in  MLL/AF4 leukemia

Free
Ricky Tirtakusuma, Katarzyna Szoltysek, Paul Milne, Vasily V. Grinev, Anetta Ptasinska, Paulynn S. Chin, Claus Meyer, Sirintra Nakjang, Jayne Y. Hehir-Kwa, Daniel Williamson, Pierre Cauchy, Peter Keane, Salam A. Assi, Minoo Ashtiani, Sophie G. Kellaway, Maria R. Imperato, Fotini Vogiatzi, Elizabeth K. Schweighart, Shan Lin, Mark Wunderlich, Janine Stutterheim, Alexander Komkov, Elena Zerkalenkova, Paul Evans, Hesta McNeill, Alex Elder, Natalia Martinez-Soria, Sarah E. Fordham, Yuzhe Shi, Lisa J. Russell, Deepali Pal, Alex Smith, Zoya Kingsbury, Jennifer Becq, Cornelia Eckert, Oskar A. Haas, Peter Carey, Simon Bailey, Roderick Skinner, Natalia Miakova, Matthew Collin, Venetia Bigley, Muzlifah Haniffa, Rolf Marschalek, Christine J. Harrison, Catherine A. Cargo, Denis Schewe, Yulia Olshanskaya, Michael J. Thirman, Peter N. Cockerill, James C. Mulloy, Helen J. Blair, Josef Vormoor, James M. Allan, Constanze Bonifer, Olaf Heidenreich, Simon Bomken
Journal: Blood
Blood (2022) 140 (17): 1875–1890.
https://doi.org/10.1182/blood.2021015036
Published: 2022
Includes: Supplemental data
Journal Articles

High BMP4 expression in low/intermediate risk BCP-ALL identifies children with poor outcomes

Open Access
Lidia M. Fernández-Sevilla, Jaris Valencia, Paula Ortiz-Sánchez, Alberto Fraile-Ramos, Pilar Zuluaga, Eva Jiménez, Rosa Sacedón, María V. Martínez-Sánchez, Janez Jazbec, Marusa Debeljak, Birthe Fedders, Martin Stanulla, Denis Schewe, Gunnar Cario, Alfredo Minguela, Manuel Ramírez, Alberto Varas, Ángeles Vicente
Journal: Blood
Blood (2022) 139 (22): 3303–3313.
https://doi.org/10.1182/blood.2021013506
Published: 2022
Includes: Supplemental data
Journal Articles

Axl, a prognostic and therapeutic target in acute myeloid leukemia mediates paracrine crosstalk of leukemia cells with bone marrow stroma

Free
Isabel Ben-Batalla, Alexander Schultze, Mark Wroblewski, Robert Erdmann, Michael Heuser, Jonas S. Waizenegger, Kristoffer Riecken, Mascha Binder, Denis Schewe, Stefanie Sawall, Victoria Witzke, Miguel Cubas-Cordova, Melanie Janning, Jasmin Wellbrock, Boris Fehse, Christian Hagel, Jürgen Krauter, Arnold Ganser, James B. Lorens, Walter Fiedler, Peter Carmeliet, Klaus Pantel, Carsten Bokemeyer, Sonja Loges
Journal: Blood
Blood (2013) 122 (14): 2443–2452.
https://doi.org/10.1182/blood-2013-03-491431
Published: 2013
Includes: Supplemental data