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Journal Articles

Epigenetic regulator genes direct lineage switching in  MLL/AF4 leukemia

Ricky Tirtakusuma, Katarzyna Szoltysek, Paul Milne, Vasily V. Grinev, Anetta Ptasinska, Paulynn S. Chin, Claus Meyer, Sirintra Nakjang, Jayne Y. Hehir-Kwa, Daniel Williamson, Pierre Cauchy, Peter Keane, Salam A. Assi, Minoo Ashtiani, Sophie G. Kellaway, Maria R. Imperato, Fotini Vogiatzi, Elizabeth K. Schweighart, Shan Lin, Mark Wunderlich, Janine Stutterheim, Alexander Komkov, Elena Zerkalenkova, Paul Evans, Hesta McNeill, Alex Elder, Natalia Martinez-Soria, Sarah E. Fordham, Yuzhe Shi, Lisa J. Russell, Deepali Pal, Alex Smith, Zoya Kingsbury, Jennifer Becq, Cornelia Eckert, Oskar A. Haas, Peter Carey, Simon Bailey, Roderick Skinner, Natalia Miakova, Matthew Collin, Venetia Bigley, Muzlifah Haniffa, Rolf Marschalek, Christine J. Harrison, Catherine A. Cargo, Denis Schewe, Yulia Olshanskaya, Michael J. Thirman, Peter N. Cockerill, James C. Mulloy, Helen J. Blair, Josef Vormoor, James M. Allan, Constanze Bonifer, Olaf Heidenreich, Simon Bomken
Journal: Blood
Blood (2022) 140 (17): 1875–1890.
https://doi.org/10.1182/blood.2021015036
Published: 2022
Includes: Supplemental data
Journal Articles

Whole-Genome CRISPR Screen Reveals the Mechanism of Relapse in Patient-Derived Cells Representing High-Risk Paediatric ALL

Katarzyna Szoltysek, PhD, Helen Blair, Sirintra Nakjang, Ricky Tirtakusuma, Mankaran Singh, Ryan Nelson, Hesta McNeill, Catherine Dodd, Melanie Beckett, Lynsey McKenzie, Edward Law, Josef Vormoor, MD PhD, Deepali Pal, Olaf Heidenreich
Journal: Blood
Blood (2019) 134 (Supplement_1): 3952.
https://doi.org/10.1182/blood-2019-124818
Published: 2019
Journal Articles

The SF3b Splicing Complex Regulates DNA Damage Response in Acute Lymphoblastic Leukemia

Shalini Sankar, Miriam Guillen Navarro, Frida Ponthan, PhD, Simon Bomken, MD, Sirintra Nakjang, Vasily Grinev, PhD, Hesta McNeill, Michel C Zwaan, MD PhD, Josef Vormoor, MD PhD, Ronald W. Stam, PhD, Olaf Heidenreich
Journal: Blood
Blood (2019) 134 (Supplement_1): 1237.
https://doi.org/10.1182/blood-2019-124787
Published: 2019
Journal Articles

A Genome-Wide RNAi Screen to Identify Novel Genes Involved in Clonal Maintenance of ALL

Frida Ponthan, PhD, Simon Bomken, PhD MBBS, Deepali Pal, PhD, Alex Elder, PhD, Hesta McNeill, Josef Vormoor, MD FRCPCH, Olaf Heidenreich, PhD
Journal: Blood
Blood (2014) 124 (21): 2390.
https://doi.org/10.1182/blood.V124.21.2390.2390
Published: 2014
Journal Articles

The Genomic Landscape Of Lineage Switch Acute Leukemia

Olaf Heidenreich, PhD, Ricky Tirtakusuma, MRes, Simon Bomken, PhD, MBBS, Dan Williamson, Sarah E Fordham, PhD, Hesta McNeill, Claus Meyer, PhD, Rolf Marschalek, PhD, Josef Vormoor, MD, Andrew Hall, Julie Irving, PhD, Helen J Blair, PhD, Dan Swan, Bronia Baker, Peter Carey, Nick Bown, David Bourn, Paul Evans, Roderick Skinner, PhD, MBChB, FRCPCH, Simon Bailey, Vikki Rand, PhD, James Allan, PhD
Journal: Blood
Blood (2013) 122 (21): 2552.
https://doi.org/10.1182/blood.V122.21.2552.2552
Published: 2013
Journal Articles

Significance of Fusion Genes for Maintenance of Leukaemia

Frida Ponthan, PhD, Hesta McNeill, Lars Buechler, PhD, Vasily Grinev, PhD, Josef Vormoor, MD, FRCPCH, Olaf Heidenreich, PhD
Journal: Blood
Blood (2011) 118 (21): 2455.
https://doi.org/10.1182/blood.V118.21.2455.2455
Published: 2011
Journal Articles

In Acute Lymphoblastic Leukaemia, Stemness Is Frequent and Ubiquitous

Klaus Rehe, MD, Kerrie Wilson, PhD, Simon Bomken, Hesta McNeill, Martin Stanulla, MD, MSc, Monique L. Den Boer, Julie Irving, PhD, Olaf Heidenreich, Josef Vormoor, MD
Journal: Blood
Blood (2010) 116 (21): 92.
https://doi.org/10.1182/blood.V116.21.92.92
Published: 2010
Journal Articles

ANGIOPOIETIN1 - a Novel Factor Implicated In MLL-Rearranged Acute Lymphoblastic Leukemia and Regulated In a Fusion Gene-Dependent Manner

Patricia Garrido Castro, Dipl.-Biochem., Simon Bomken, MD, Lidija Seslija, Ronald Stam, PhD, Elda S Latif, Michael A Batey, MPhil, Hesta McNeill, Rob Pieters, MD, PhD, Josef Vormoor, MD, Prof., Johann Greil, MD, Olaf Heidenreich, PhD
Journal: Blood
Blood (2010) 116 (21): 66.
https://doi.org/10.1182/blood.V116.21.66.66
Published: 2010
Journal Articles

Disease Propagating Blasts in Standard and High Risk Acute Lymphoblastic Leukemia Are Frequent and of Diverse Immunophenotype.

Klaus Rehe, MD, Kerrie Wilson, BSc, (Hons), Hesta McNeill, Martin Schrappe, MD, Julie Irving, PhD, Josef Vormoor, MD, FRCPCH
Journal: Blood
Blood (2009) 114 (22): 1421.
https://doi.org/10.1182/blood.V114.22.1421.1421
Published: 2009