Page 1 | Search Results | Blood | American Society of Hematology

1-20 of 20

Sort by

Sort Order Select

Journal Articles

Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia

Ricky Tirtakusuma, Katarzyna Szoltysek, Paul Milne, Vasily V. Grinev, Anetta Ptasinska, Paulynn S. Chin, Claus Meyer, Sirintra Nakjang, Jayne Y. Hehir-Kwa, Daniel Williamson, Pierre Cauchy, Peter Keane, Salam A. Assi, Minoo Ashtiani, Sophie G. Kellaway, Maria R. Imperato, Fotini Vogiatzi, Elizabeth K. Schweighart, Shan Lin, Mark Wunderlich, Janine Stutterheim, Alexander Komkov, Elena Zerkalenkova, Paul Evans, Hesta McNeill, Alex Elder, Natalia Martinez-Soria, Sarah E. Fordham, Yuzhe Shi, Lisa J. Russell, Deepali Pal, Alex Smith, Zoya Kingsbury, Jennifer Becq, Cornelia Eckert, Oskar A. Haas, Peter Carey, Simon Bailey, Roderick Skinner, Natalia Miakova, Matthew Collin, Venetia Bigley, Muzlifah Haniffa, Rolf Marschalek, Christine J. Harrison, Catherine A. Cargo, Denis Schewe, Yulia Olshanskaya, Michael J. Thirman, Peter N. Cockerill, James C. Mulloy, Helen J. Blair, Josef Vormoor, James M. Allan, Constanze Bonifer, Olaf Heidenreich, Simon Bomken

Blood (2022) 140 (17): 1875–1890.

https://doi.org/10.1182/blood.2021015036

Published: 2022

Includes: Supplemental data

Journal Articles

PLCG1 is required for AML1-ETO leukemia stem cell self-renewal

Blood (2022) 139 (7): 1080–1097.

https://doi.org/10.1182/blood.2021012778

Published: 2022

Includes: Supplemental data

Journal Articles

Loss of Phospholipase C Gamma 1 (PLCG1) Impairs AML1-ETO Induced Leukemia Stem Cell Self-Renewal

Blood (2019) 134 (Supplement_1): 531.

https://doi.org/10.1182/blood-2019-121996

Published: 2019

Journal Articles

Isoform Specific Regulation of Acute Myeloid Leukemia Maintenance By Wilms Tumor 1

Sandeep Potluri, MA, MBBChir, MRCP, Salam A. Assi, PhD, Suyin Paulynn Chin, PhD, Anetta Ptasinska, PhD, Daniel Coleman, PhD, Peter Cockerill, PhD, Constanze Bonifer, PhD

Blood (2019) 134 (Supplement_1): 1232.

https://doi.org/10.1182/blood-2019-122533

Published: 2019

Journal Articles

A FOXO1-induced oncogenic network defines the AML1-ETO preleukemic program

Shan Lin, Anetta Ptasinska, Xiaoting Chen, Mahesh Shrestha, Salam A. Assi, Paulynn S. Chin, Maria R. Imperato, B. J. Aronow, Jingsong Zhang, Matthew T. Weirauch, Constanze Bonifer, James C. Mulloy

Blood (2017) 130 (10): 1213–1222.

https://doi.org/10.1182/blood-2016-11-750976

Published: 2017

Includes: Supplemental data

Journal Articles

Identification of CCND2 As a RUNX1/ETO Target Required for Leukaemic Propagation

Lynsey McKenzie, PhD, Natalia Martinez-Soria, PhD, Julia Draper, DPhil, Sirintra Nakjang, PhD, Helen J Blair, PhD, Christian Wichmann, MD, Josef Vormoor, MD FRCPCH, Constanze Bonifer, PhD, Georges Lacaud, PhD, Olaf Heidenreich, PhD

Blood (2016) 128 (22): 835.

https://doi.org/10.1182/blood.V128.22.835.835

Published: 2016

Journal Articles

The Transcriptome Heterogeneity of MLL-Fusion ALL Is Driven By Fusion Partners Via Distinct Chromatin Binding

Shan Lin, Anetta Ptasinska, PhD, Salam Adli Assi, Jon Kerry, Ruhikanta A. Meetei, PhD, Roger T. Luo, PhD, Michael J. Thirman, MD, Thomas Milne, PhD, Constanze Bonifer, PhD, James C. Mulloy, PhD

Blood (2016) 128 (22): 576.

https://doi.org/10.1182/blood.V128.22.576.576

Published: 2016

Journal Articles

Identification of a Dynamic Core Transcriptional Network in t(8;21) AML Regulating Differentiation Block and Self-Renewal

Anetta Ptasinska, PhD, Salam Assi, PhD, Natalia Martinez-Soria, PhD, Maria Rosaria Imperato, PhD, Jason Piper, PhD, Pierre Cauchy, PhD, Anna Pickin, Sally James, PhD, Maarten Hoogenkamp, PhD, Daniel G Tenen, MD, Sascha Ott, PhD, David R Westhead, PhD, Peter N Cockerill, PhD, Olaf Heidenreich, PhD, Constanze Bonifer, PhD

Blood (2014) 124 (21): 1061.

https://doi.org/10.1182/blood.V124.21.1061.1061

Published: 2014

Journal Articles

RUNX1 positively regulates a cell adhesion and migration program in murine hemogenic endothelium prior to blood emergence

Michael Lie-A-Ling, Elli Marinopoulou, Yaoyong Li, Rahima Patel, Monika Stefanska, Constanze Bonifer, Crispin Miller, Valerie Kouskoff, Georges Lacaud

Blood (2014) 124 (11): e11–e20.

https://doi.org/10.1182/blood-2014-04-572958

Published: 2014

Includes: Multimedia, Supplemental data

Journal Articles

Lineage-inappropriate PAX5 expression in t(8;21) acute myeloid leukemia requires signaling-mediated abrogation of polycomb repression

Debleena Ray, So Yeon Kwon, Hiromi Tagoh, Olaf Heidenreich, Anetta Ptasinska, Constanze Bonifer

Blood (2013) 122 (5): 759–769.

https://doi.org/10.1182/blood-2013-02-482497

Published: 2013

Includes: Supplemental data

Journal Articles

Identification of Sox4 As Key Oncogene in Leukemias with Mutated or Silenced C/EBPα

Hong Zhang, PhD, Min Ye, PhD, Meritxell Alberich-Jordà, PhD, Giovanni Amabile, PhD, Philipp B. Staber, M.D., Peter J. M. Valk, PhD, Ruud Delwel, PhD, Véronique Lefebvre, PhD, Constanze Bonifer, PhD, Daniel G. Tenen, MD

Blood (2012) 120 (21): 114.

https://doi.org/10.1182/blood.V120.21.114.114

Published: 2012

Journal Articles

GFI1 and GFI1B control the loss of endothelial identity of hemogenic endothelium during hematopoietic commitment

Christophe Lancrin, Milena Mazan, Monika Stefanska, Rahima Patel, Monika Lichtinger, Guilherme Costa, Özge Vargel, Nicola K. Wilson, Tarik Möröy, Constanze Bonifer, Berthold Göttgens, Valerie Kouskoff, Georges Lacaud

Blood (2012) 120 (2): 314–322.

https://doi.org/10.1182/blood-2011-10-386094

Published: 2012

Includes: Multimedia, Supplemental data

Journal Articles

Macrophage development from HSCs requires PU.1-coordinated microRNA expression

Saeed Ghani, Pia Riemke, Jörg Schönheit, Dido Lenze, Jürgen Stumm, Maarten Hoogenkamp, Anne Lagendijk, Sven Heinz, Constanze Bonifer, Jeroen Bakkers, Salim Abdelilah-Seyfried, Michael Hummel, Frank Rosenbauer

Blood (2011) 118 (8): 2275–2284.

https://doi.org/10.1182/blood-2011-02-335141

Published: 2011

Includes: Supplemental data

Journal Articles

Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells

Mathias Leddin, Chiara Perrod, Maarten Hoogenkamp, Saeed Ghani, Salam Assi, Sven Heinz, Nicola K. Wilson, George Follows, Jörg Schönheit, Lena Vockentanz, Ali M. Mosammam, Wei Chen, Daniel G. Tenen, David R. Westhead, Berthold Göttgens, Constanze Bonifer, Frank Rosenbauer

Blood (2011) 117 (10): 2827–2838.

https://doi.org/10.1182/blood-2010-08-302976

Published: 2011

Includes: Supplemental data

Journal Articles

Early chromatin unfolding by RUNX1: a molecular explanation for differential requirements during specification versus maintenance of the hematopoietic gene expression program

Maarten Hoogenkamp, Monika Lichtinger, Hanna Krysinska, Christophe Lancrin, Deborah Clarke, Andrew Williamson, Luca Mazzarella, Richard Ingram, Helle Jorgensen, Amanda Fisher, Daniel G. Tenen, Valerie Kouskoff, Georges Lacaud, Constanze Bonifer

Blood (2009) 114 (2): 299–309.

https://doi.org/10.1182/blood-2008-11-191890

Published: 2009

Includes: Supplemental data

Journal Articles

Stem cell–specific epigenetic priming and B cell–specific transcriptional activation at the mouse Cd19 locus

Korden Walter, Constanze Bonifer, Hiromi Tagoh

Blood (2008) 112 (5): 1673–1682.

https://doi.org/10.1182/blood-2008-02-142786

Published: 2008

Includes: Supplemental data

Journal Articles

Regulation of the PU.1 Gene by Sense and Functional Antisense RNAs Generated through the Same Chromatin Architecture.

Alex Ebralidze, PhD, Pu Zhang, MD, Frank Rosenbauer, Ph.D., Gang Huang, Ph.D., Ulrich Steidl, M.D., Tajhal Dayaram, B.S., Florence Guibal, Ph.D., Johanna Klupp, B.S., Dana Neel, Constanze Bonifer, Ph.D., Daniel G. Tenen, M.D.

Blood (2006) 108 (11): 781.

https://doi.org/10.1182/blood.V108.11.781.781

Published: 2006

Journal Articles

Dynamic reorganization of chromatin structure and selective DNA demethylation prior to stable enhancer complex formation during differentiation of primary hematopoietic cells in vitro

Hiromi Tagoh, Svitlana Melnik, Pascal Lefevre, Suyinn Chong, Arthur D. Riggs, Constanze Bonifer

Blood (2004) 103 (8): 2950–2955.

https://doi.org/10.1182/blood-2003-09-3323

Published: 2004

Journal Articles

Lymphodepletion in the Apc Min/ + mouse model of intestinal tumorigenesis

P. Louise Coletta, Albrecht M. Müller, Elena A. Jones, Bettina Mühl, Sarah Holwell, Deborah Clarke, Josephine L. Meade, Graham P. Cook, Gillian Hawcroft, Frederique Ponchel, Wai K. Lam, Ken A. MacLennan, Mark A. Hull, Constanze Bonifer, Alexander F. Markham

Blood (2004) 103 (3): 1050–1058.

https://doi.org/10.1182/blood-2003-03-0707

Published: 2004

Journal Articles

Regulation of the human endothelial cell protein C receptor gene promoter by multiple Sp1 binding sites

James B. Rance, George A. Follows, Peter N. Cockerill, Constanze Bonifer, David A. Lane, Rachel E. Simmonds

Blood (2003) 101 (11): 4393–4401.

https://doi.org/10.1182/blood-2002-05-1570

Published: 2003

NARROW

Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia

PLCG1 is required for AML1-ETO leukemia stem cell self-renewal

Loss of Phospholipase C Gamma 1 (PLCG1) Impairs AML1-ETO Induced Leukemia Stem Cell Self-Renewal

Isoform Specific Regulation of Acute Myeloid Leukemia Maintenance By Wilms Tumor 1

A FOXO1-induced oncogenic network defines the AML1-ETO preleukemic program

Identification of CCND2 As a RUNX1/ETO Target Required for Leukaemic Propagation

The Transcriptome Heterogeneity of MLL-Fusion ALL Is Driven By Fusion Partners Via Distinct Chromatin Binding

Identification of a Dynamic Core Transcriptional Network in t(8;21) AML Regulating Differentiation Block and Self-Renewal

RUNX1 positively regulates a cell adhesion and migration program in murine hemogenic endothelium prior to blood emergence

Lineage-inappropriate PAX5 expression in t(8;21) acute myeloid leukemia requires signaling-mediated abrogation of polycomb repression

Identification of Sox4 As Key Oncogene in Leukemias with Mutated or Silenced C/EBPα

GFI1 and GFI1B control the loss of endothelial identity of hemogenic endothelium during hematopoietic commitment

Macrophage development from HSCs requires PU.1-coordinated microRNA expression

Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells

Early chromatin unfolding by RUNX1: a molecular explanation for differential requirements during specification versus maintenance of the hematopoietic gene expression program

Stem cell–specific epigenetic priming and B cell–specific transcriptional activation at the mouse Cd19 locus

Regulation of the PU.1 Gene by Sense and Functional Antisense RNAs Generated through the Same Chromatin Architecture.

Dynamic reorganization of chromatin structure and selective DNA demethylation prior to stable enhancer complex formation during differentiation of primary hematopoietic cells in vitro

Lymphodepletion in the Apc Min/ + mouse model of intestinal tumorigenesis

Regulation of the human endothelial cell protein C receptor gene promoter by multiple Sp1 binding sites

Email alerts

ASH Publications

American Society of Hematology

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only