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Luca Mazzarella
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Journal Articles

Experience with IMGN632, a Novel CD123-Targeting Antibody-Drug Conjugate (ADC), in Frontline Patients with Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

Naveen Pemmaraju, Giovanni Martinelli, Elisabetta Todisco, Andrew A. Lane, Evelyn Acuña-Cruz, Eric Deconinck, Eunice S. Wang, Kendra Sweet, David A Rizzieri, Giovanni Marconi, Luca Mazzarella, Daniel J. DeAngelo, Pau Montesinos, Federica Gigli, Harry P. Erba, Marina Konopleva, Hagop Kantarjian, Roland B. Walter, Ahmed Aribi, Delphine Lebon, Moshe Y. Levy, Callum M Sloss, Kara E Malcolm, Patrick A Zweidler-McKay, Naval Daver
Journal: Blood
Blood (2021) 138 (Supplement 1): 1284.
https://doi.org/10.1182/blood-2021-146666
Published: 2021
Journal Articles

A Study of IMGN632, a Novel CD123-Targeting Antibody-Drug Conjugate, for Patients with Frontline and Relapsed/Refractory Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

Naveen Pemmaraju, Giovanni Marconi, Elisabetta Todisco, Pau Montesinos, Andrew A. Lane, Kendra Sweet, Eunice S. Wang, Eric Deconinck, David A Rizzieri, Roland B. Walter, Ahmed Aribi, Delphine Lebon, Moshe Y. Levy, Luca Mazzarella, Giovanni Martinelli, Federica Gigli, Harry P. Erba, Evelyn Acuña-Cruz, Marina Konopleva, Hagop Kantarjian, Callum M Sloss, Jiuzhou Wang, Kara E Malcolm, Patrick A Zweidler-McKay, Daniel J. DeAngelo, Naval Daver
Journal: Blood
Blood (2021) 138 (Supplement 1): 4429.
https://doi.org/10.1182/blood-2021-146681
Published: 2021
Journal Articles

Clinical Profile of IMGN632, a Novel CD123-Targeting Antibody-Drug Conjugate (ADC), in Patients with Relapsed/Refractory (R/R) Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

Naveen Pemmaraju, MD, Giovanni Martinelli, MD, Elisabetta Todisco, MDPhD, Andrew A Lane, MD PhD, Evelyn Acuña-Cruz, MD, Eric Deconinck, MDPhD, Eunice S. Wang, MD, Kendra L. Sweet, MD MS, David A Rizzieri, MD, Luca Mazzarella, MDPhD, Daniel J. DeAngelo, MD PhD, Pau Montesinos, MD PhD, Corrado Tarella, Harry P. Erba, MD PhD, Marina Konopleva, MD PhD, Hagop M. Kantarjian, MD, Callum M Sloss, PhD, Kara E Malcolm, RN, Patrick A Zweidler-McKay, MDPhD, Naval Daver, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 11–13.
https://doi.org/10.1182/blood-2020-139903
Published: 2020
Journal Articles

Obesity As a Risk Factor for Acute Promyelocytic Leukemia. Results from Population and Case-Control Studies Across Western Countries and Correlation with Gene Expression in the TCGA

Luca Mazzarella, MD PhD, Edoardo Botteri, PhD, Anthony Matthews, MPhil, Davide Disalvatore, PhD, Vincenzo Bagnardi, PhD, Massimo Breccia, MD, Pau Montesinos, MD PhD, Teresa Bernal, MD PhD, Cristina Gil, MD, Timothy J. Ley, MD, Miguel A. Sanz, MD PhD, Krishnan Bhaskaran, PhD, Francesco Lo Coco, MD, Pier Giuseppe Pelicci, MD
Journal: Blood
Blood (2016) 128 (22): 448.
https://doi.org/10.1182/blood.V128.22.448.448
Published: 2016
Journal Articles

Inhibition of the Histone Demethylase LSD1 Combined with Caloric Restriction or IGF1/Insulin Inhibition Leads to Durable Responses in a Preclinical Model of Acute Myeloid Leukemia

Luca Mazzarella, MD PhD, Tiphanie Durfort, Rani Pallavi, Elena Mylonas, Paolo Falvo, Anna Giulia Sanarico, Massimo Stendardo, Luciano Giaco', Anna Russo, Lucilla Luzi, Massimiliano Mazza, Giulia De Conti, Paola Vianello, Pier Luigi Rossi, Elena Ceccacci, Mohamed Elgendy, Marco Giorgio, Ciro Mercurio, Saverio Minucci, Pier Giuseppe Pelicci
Journal: Blood
Blood (2015) 126 (23): 459.
https://doi.org/10.1182/blood.V126.23.459.459
Published: 2015
Journal Articles

Modelling The Influence Of Diet On APL Identifies Insulin-Growth Factor 1 As A Central Mediator and Provides A Mechanistic Rationale For Therapeutic Weight Loss

Luca Mazzarella, MD. PhD, Tiphanie Durfort, PhD, Pier Giuseppe Pelicci
Journal: Blood
Blood (2013) 122 (21): 833.
https://doi.org/10.1182/blood.V122.21.833.833
Published: 2013
Journal Articles

Insulin/IGF1 Pathway Inhibition in Combination with All-Trans Retinoic Acid in Acute Promyelocytic Leukemia

Tiphanie Durfort, Luca Mazzarella, Pier Giuseppe Pelicci
Journal: Blood
Blood (2012) 120 (21): 1347.
https://doi.org/10.1182/blood.V120.21.1347.1347
Published: 2012
Journal Articles

Increased BMI correlates with higher risk of disease relapse and differentiation syndrome in patients with acute promyelocytic leukemia treated with the AIDA protocols

Clinical Trials & Observations
Massimo Breccia, Luca Mazzarella, Vincenzo Bagnardi, Davide Disalvatore, Giuseppina Loglisci, Giuseppe Cimino, Anna Maria Testi, Giuseppe Avvisati, Maria Concetta Petti, Clara Minotti, Roberto Latagliata, Robin Foà, Pier Giuseppe Pelicci, Francesco Lo-Coco
Journal: Blood
Blood (2012) 119 (1): 49–54.
https://doi.org/10.1182/blood-2011-07-369595
Published: 2012
Journal Articles

Increased Body Mass Index Correlates with Higher Risk of Disease Relapse and Differentiation Syndrome in Patients with Acute Promyelocytic Leukemia Treated with Aida Protocols

Massimo Breccia, MD, Luca Mazzarella, MD, Giuseppina Loglisci, Vincenzo Bagnardi, Davide Disalvatore, Roberto Latagliata, Anna Maria Testi, Giuseppe Cimino, MD, Giuseppe Avvisati, MD, Maria Concetta Petti, Pier Guiseppe Pelicci, Robin Foá, MD, Francesco Lo Coco
Journal: Blood
Blood (2011) 118 (21): 4866.
https://doi.org/10.1182/blood.V118.21.4866.4866
Published: 2011
Journal Articles

Embryonic stem cell–derived hemangioblasts remain epigenetically plastic and require PRC1 to prevent neural gene expression

Brief Report
Luca Mazzarella, Helle F. Jørgensen, Jorge Soza-Ried, Anna V. Terry, Stella Pearson, Georges Lacaud, Valerie Kouskoff, Matthias Merkenschlager, Amanda G. Fisher
Journal: Blood
Blood (2011) 117 (1): 83–87.
https://doi.org/10.1182/blood-2010-03-273128
Published: 2011
Includes: Supplemental data
Journal Articles

The Combination of Cyclophosphamide and Thalidomide During Induction Therapy for Multiple Myeloma Results in a High Rate of Stem Cell Mobilization Failure.

Holger W Auner, Luca Mazzarella, Lucy Cook, Richard Szydlo, Francesca Saltarelli, Jiri Pavlu, Jane F Apperley, Amin Rahemtulla
Journal: Blood
Blood (2009) 114 (22): 2147.
https://doi.org/10.1182/blood.V114.22.2147.2147
Published: 2009
Journal Articles

Early chromatin unfolding by RUNX1: a molecular explanation for differential requirements during specification versus maintenance of the hematopoietic gene expression program

Maarten Hoogenkamp, Monika Lichtinger, Hanna Krysinska, Christophe Lancrin, Deborah Clarke, Andrew Williamson, Luca Mazzarella, Richard Ingram, Helle Jorgensen, Amanda Fisher, Daniel G. Tenen, Valerie Kouskoff, Georges Lacaud, Constanze Bonifer
Journal: Blood
Blood (2009) 114 (2): 299–309.
https://doi.org/10.1182/blood-2008-11-191890
Published: 2009
Includes: Supplemental data