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Andrew A. Lane
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Journal Articles

Phase 2 Multicenter Trial of Tagraxofusp in Combination with Venetoclax and Azacitidine in Adults with Previously Untreated CD123+ Acute Myeloid Leukemia Ineligible for Intensive Chemotherapy

Naval Daver, Naveen Pemmaraju, Mikkael A. Sekeres, Amir T. Fathi, Andrew A. Lane, Anna Compagnoni, Ira Gupta, Alessandra Tosolini, Jessica Garzon, Hagop M. Kantarjian
Journal: Blood
Blood (2024) 144 (Supplement 1): 4265.1.
https://doi.org/10.1182/blood-2024-193593
Published: 2024
Journal Articles

Machine Learning Derived Three-Parameter Prognostic Model for Survival in Patients with BPDCN

Shai O. Shimony, Julia Keating, Marlise R. Luskin, Christopher Fay, Florian Renosi, Eric Deconinck, Francine Garnache-Ottou, Donna S. Neuberg, Nicole R. Leboeuf, Andrew A. Lane
Journal: Blood
Blood (2024) 144 (Supplement 1): 321.
https://doi.org/10.1182/blood-2024-198275
Published: 2024
Journal Articles

A Multi-Site Break through Cancer Trial: Phase II Study Investigating Dual Inhibition of BCL2 and Menin in AML MRD Using the Combination of Venetoclax and Revumenib (Trial In Progress)

Ghayas C. Issa, Alexander J. Ambinder, Wenbin Xiao, Scott Manalis, Alex K Shalek, Lukasz P. Gondek, Alex Kentsis, Nicholas J. Short, Naval Daver, Jing Ning, Lianchun Xiao, Michael Hemann, Ken Chen, Keyur P. Patel, Pavan Bachireddy, Andrew A. Lane, Marina Konopleva, Omar Abdel-Wahab, Jeffrey J. Molldrem, Ross L Levine, Mark J. Levis, Richard M Stone, Michael Andreeff, Farhad Ravandi, Aaron D. Goldberg, Jacqueline S. Garcia
Journal: Blood
Blood (2024) 144 (Supplement 1): 4265.2.
https://doi.org/10.1182/blood-2024-201582
Published: 2024
Journal Articles

Tagraxofusp Achieves Anti-Tumor Activity with Rapid Restoration of Normal Hematopoiesis in Treatment-Naïve Patients with Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN): Subanalysis of a Pivotal Trial

Marina Konopleva, Naveen Pemmaraju, Kendra L. Sweet, Anthony S. Stein, David A. Rizzieri, Eunice S. Wang, Sumithira Vasu, Todd Rosenblat, Michael Zuurman, Ira Gupta, Andrew A. Lane
Journal: Blood
Blood (2024) 144 (Supplement 1): 1515.
https://doi.org/10.1182/blood-2024-200230
Published: 2024
Journal Articles

Dual Bclxl and BCL2 Inhibition with Navitoclax (NAV), Venetoclax (VEN), and Decitabine (DEC) for Advanced Myeloid Neoplasms (MN): Safety and Biological Activity in a Phase 1 Study

Evan C. Chen, Yiwen Liu, Hayden L. Bell, Ilene A. Galinsky, Marlise R. Luskin, Eric S. Winer, Maximilian Stahl, Rahul Vedula, Virginia O. Volpe, Daniel J. DeAngelo, Karen Quillen, Jeremy Ryan, Emma-Jayne Minihane, Matthew Hersch, Rebecca Leonard, Donna S. Neuberg, Richard M. Stone, Anthony G. Letai, Andrew A. Lane, Jacqueline S. Garcia
Journal: Blood
Blood (2024) 144 (Supplement 1): 4580.
https://doi.org/10.1182/blood-2024-198284
Published: 2024
Journal Articles

How I treat Blastic Plasmacytoid Dendritic Cell Neoplasm

Mohamed A Kharfan-Dabaja, Andrew A. Lane, Naveen Pemmaraju
Journal: Blood
Blood blood.2024024262.
https://doi.org/10.1182/blood.2024024262
Published: 2024
Journal Articles

Post-Transplant T Cell Clonotype Diversity Is Associated with Survival in Patients with TP53-Mutated Acute Myeloid Leukemia

Nurefsan Sariipek, Kseniia R. Safina, Corey Cutler, Vincent T. Ho, John Koreth, Coleman Lindsley, Marlise R. Luskin, Jacqueline S. Garcia, Doreen Hearsey, Wesley S Lu, Shuqiang Li, Kenneth J. Livak, Gabriel K. Griffin, Robert J. Soiffer, Jerome Ritz, Catherine J Wu, Joseph H. Antin, Andrew A. Lane, Peter Van Galen, Mahasweta Gooptu
Journal: Blood
Blood (2023) 142 (Supplement 1): 2176.
https://doi.org/10.1182/blood-2023-181863
Published: 2023
Journal Articles

A Simple Prediction Model of Outcomes after Allogeneic Hematopoietic Stem Cell Transplant (HCT) in Myelodysplastic Syndromes Using HCT-Comorbidity Index, Cytogenetic Risk, and Platelet Count

Stacey M Frumm, Haesook T. Kim, Amar H Kelkar, Vincent T. Ho, Mahasweta Gooptu, Christopher James Gibson, John Koreth, Roman M. Shapiro, Rizwan Romee, Sarah Nikiforow, Joseph H. Antin, Robert J. Soiffer, Benjamin Rolles, Shai Shimony, Jan Philipp Bewersdorf, Tariq Kewan, Abdulrahman Alhajahjeh, Marlise R. Luskin, Jacqueline S. Garcia, Evan C. Chen, Andrew A. Lane, Martha Wadleigh, Eric S. Winer, Richard M Stone, Daniel J. DeAngelo, Amer M. Zeidan, Coleman Lindsley, Corey Cutler, Maximilian Stahl
Journal: Blood
Blood (2023) 142 (Supplement 1): 2246.
https://doi.org/10.1182/blood-2023-185315
Published: 2023
Journal Articles

Defining a Targetable Leukemia Intrinsic Dependency on Noncanonical PI3Kgamma Signaling

Qingyu Luo, Evangeline G. Raulston, Miguel A. Prado, Xiaowei Wu, Kira Gritsman, Kezhi Yan, Christopher A. G. Booth, Ran Xu, Peter van Galen, John G. Doench, Shai Shimony, Henry W. Long, Donna S. Neuberg, Joao A. Paulo, Andrew A. Lane
Journal: Blood
Blood (2023) 142 (Supplement 1): 578.
https://doi.org/10.1182/blood-2023-178895
Published: 2023
Journal Articles

Organ Involvement in BPDCN Is Associated with Sun Exposure History, TET2 and RAS Mutations, and Survival

Shai Shimony, Julia Keating, Christopher Fay, Marlise R. Luskin, Donna S. Neuberg, Nicole R. Leboeuf, Andrew A. Lane
Journal: Blood
Blood (2023) 142 (Supplement 1): 2865.
https://doi.org/10.1182/blood-2023-172975
Published: 2023
Journal Articles

Post Allogeneic Stem Cell Transplant Outcomes Following Response to Hypomethylating Agent Therapy in Myelodysplastic Syndromes Are Predicted By Persistent International Prognostic Scoring System-Molecular Risk

Stacey M Frumm, Haesook T. Kim, Amar H Kelkar, Vincent T. Ho, Mahasweta Gooptu, Christopher James Gibson, John Koreth, Roman M. Shapiro, Rizwan Romee, Sarah Nikiforow, Joseph H. Antin, Robert J. Soiffer, Benjamin Rolles, Shai Shimony, Jan Philipp Bewersdorf, Tariq Kewan, Abdulrahman Alhajahjeh, Marlise R. Luskin, Jacqueline S. Garcia, Evan C. Chen, Andrew A. Lane, Martha Wadleigh, Eric S. Winer, Richard M Stone, Daniel J. DeAngelo, Amer M. Zeidan, Coleman Lindsley, Corey Cutler, Maximilian Stahl
Journal: Blood
Blood (2023) 142 (Supplement 1): 3618.
https://doi.org/10.1182/blood-2023-185220
Published: 2023
Journal Articles

Tagraxofusp in Combination with Azacitidine and Venetoclax in Newly Diagnosed CD123+ Acute Myeloid Leukemia, Expansion Cohort of a Phase 1b Multicenter Trial

Andrew A. Lane, Jacqueline S. Garcia, Evangeline G. Raulston, Jada L. Garzon, Ilene Galinsky, Emilie W. Baxter, Rebecca Leonard, Daniel J. DeAngelo, Marlise R. Luskin, Christopher R. Reilly, Maximilian Stahl, Richard M Stone, Rahul Vedula, Martha Wadleigh, Eric S. Winer, Tariq Mughal, Christopher Brooks, Ira V. Gupta, Kristen E. Stevenson, Donna S. Neuberg, Siyang Ren, Marina Y. Konopleva, Anthony Stein, Naveen Pemmaraju
Journal: Blood
Blood (2023) 142 (Supplement 1): 4277.
https://doi.org/10.1182/blood-2023-180010
Published: 2023
Journal Articles

DDX41 : here, there…and everywhere

Christopher R. Reilly, Andrew A. Lane
Journal: Blood
Blood (2023) 142 (14): 1177–1178.
https://doi.org/10.1182/blood.2023021850
Published: 2023
Journal Articles

North American Blastic Plasmacytoid Dendritic Cell Neoplasm Consortium: position on standards of care and areas of need

Naveen Pemmaraju, Hagop Kantarjian, Kendra Sweet, Eunice Wang, Jayastu Senapati, Nathaniel R. Wilson, Marina Konopleva, Arthur E. Frankel, Vikas Gupta, Ruben Mesa, Matthew Ulrickson, Edward Gorak, Sumeet Bhatia, Tulin Budak-Alpdogan, James Mason, Maria Teresa Garcia-Romero, Norma Lopez-Santiago, Gabriela Cesarman-Maus, Pankit Vachhani, Sangmin Lee, Vijaya Raj Bhatt, William Blum, Roland B. Walter, Dale Bixby, Ivana Gojo, Madeleine Duvic, Raajit K. Rampal, Marcos de Lima, James Foran, Amir T. Fathi, Aric Cameron Hall, Meagan A. Jacoby, Jeffrey Lancet, Gabriel Mannis, Anthony S. Stein, Alice Mims, David Rizzieri, Rebecca Olin, Alexander Perl, Gary Schiller, Paul Shami, Richard M. Stone, Stephen Strickland, Matthew J. Wieduwilt, Naval Daver, Farhad Ravandi, Sumithira Vasu, Monica Guzman, Gail J. Roboz, Joseph Khoury, Muzaffar Qazilbash, Phyu P. Aung, Branko Cuglievan, Yazan Madanat, Mohamed A. Kharfan-Dabaja, Anna Pawlowska, Justin Taylor, Martin Tallman, Prajwal Dhakal, Andrew A. Lane
Journal: Blood
Blood (2023) 141 (6): 567–578.
https://doi.org/10.1182/blood.2022017865
Published: 2023
Journal Articles

BPDCN MYB Fusions Bind Cell Cycle Gene Promoters, Reactivate Self-Renewal in Progenitor Cells and Induce Myeloid/Dendritic Leukemia

Christopher A.G. Booth, Juliette M.C. Bouyssou, Katsuhiro Togami, Andrew A. Lane
Journal: Blood
Blood (2022) 140 (Supplement 1): 2000–2001.
https://doi.org/10.1182/blood-2022-159150
Published: 2022
Journal Articles

Tagraxofusp, an Anti-CD123 Therapy, in Patients with Blastic Plasmacytoid Dendritic Cell Neoplasm and Prior or Concomitant Hematologic Malignancies: Subgroup Analysis of a Pivotal Trial

Naveen Pemmaraju, Marina Konopleva, Kendra Sweet, Anthony S. Stein, Sumithira Vasu, David A Rizzieri, Eunice S. Wang, Hagop Kantarjian, Christopher L. Brooks, Carole Paley, Tariq I. Mughal, Andrew A. Lane
Journal: Blood
Blood (2022) 140 (Supplement 1): 6155–6157.
https://doi.org/10.1182/blood-2022-159970
Published: 2022
Journal Articles

Clonal Hematopoiesis Evolves into Dendritic Cell Neoplasm through the Acquisition of UV Mutations in the Skin

Peter Van Galen, Gabriel K. Griffin, Christopher A.G. Booth, Katsuhiro Togami, Sun Sook Chung, Daniel Ssozi, Julia A. Verga, Juliette M.C. Bouyssou, Yoke Seng Lee, Vignesh Shanmugam, Nicole R. LeBoeuf, Elizabeth A. Morgan, Bradley E. Bernstein, Volker Hovestadt, Andrew A. Lane
Journal: Blood
Blood (2022) 140 (Supplement 1): 1998–1999.
https://doi.org/10.1182/blood-2022-163666
Published: 2022
Journal Articles

Tagraxofusp, an Anti-CD123 Therapy, in Patients with Blastic Plasmacytoid Dendritic Cell Neoplasm: Subanalyses of a Pivotal Trial By Age and Baseline Disease Involvement

Naveen Pemmaraju, Marina Konopleva, Kendra Sweet, Anthony S. Stein, Sumithira Vasu, David A. Rizzieri, Eunice S. Wang, Hagop Kantarjian, Christopher L Brooks, Tariq I. Mughal, Andrew A. Lane
Journal: Blood
Blood (2021) 138 (Supplement 1): 874.
https://doi.org/10.1182/blood-2021-145109
Published: 2021
Journal Articles

Experience with IMGN632, a Novel CD123-Targeting Antibody-Drug Conjugate (ADC), in Frontline Patients with Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

Naveen Pemmaraju, Giovanni Martinelli, Elisabetta Todisco, Andrew A. Lane, Evelyn Acuña-Cruz, Eric Deconinck, Eunice S. Wang, Kendra Sweet, David A Rizzieri, Giovanni Marconi, Luca Mazzarella, Daniel J. DeAngelo, Pau Montesinos, Federica Gigli, Harry P. Erba, Marina Konopleva, Hagop Kantarjian, Roland B. Walter, Ahmed Aribi, Delphine Lebon, Moshe Y. Levy, Callum M Sloss, Kara E Malcolm, Patrick A Zweidler-McKay, Naval Daver
Journal: Blood
Blood (2021) 138 (Supplement 1): 1284.
https://doi.org/10.1182/blood-2021-146666
Published: 2021
Journal Articles

Antifungal Prophylaxis: Impact on Outcomes of Newly Diagnosed AML Patients Treated with a Hypomethylating Agent and Venetoclax

Evan C. Chen, Yiwen Liu, Eric S. Winer, Marlise R. Luskin, Martha Wadleigh, Andrew A. Lane, Rahul S. Vedula, Coleman Lindsley, Kevin Copson, Anne Charles, Donna S. Neuberg, Nicolas C. Issa, Daniel J. DeAngelo, Richard M. Stone, Jacqueline S. Garcia
Journal: Blood
Blood (2021) 138 (Supplement 1): 4126.
https://doi.org/10.1182/blood-2021-148717
Published: 2021