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Branko Cuglievan
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Journal Articles

Phase II Study of Pedi-Crib: Mini-Hyper-CVD with Condensed Rituximab, Inotuzumab Ozogamicin and Blinatumomab (cRIB) for Relapsed Therapy for Pediatric Patients with B-Cell Lineage Acute Lymphocytic Leukemia

David McCall, Amber Gibson, Miriam B. Garcia, Cesar Nunez, Michael E. Roth, Branko Cuglievan
Journal: Blood
Blood (2024) 144 (Supplement 1): 1431.1.
https://doi.org/10.1182/blood-2024-212144
Published: 2024
Journal Articles

A Phase I Study Investigating the Combination of the Ziftomenib, Venetoclax and Azacitidine (ZiVA) in Pediatric Relapsed and Refractory Acute Leukemias

David McCall, Branko Cuglievan, Amber Gibson, Miriam B. Garcia, Michael E. Roth, Cesar Nunez
Journal: Blood
Blood (2024) 144 (Supplement 1): 1504.4.
https://doi.org/10.1182/blood-2024-208146
Published: 2024
Journal Articles

Phase I/II Study of the All-Oral Combination of Revumenib (SNDX-5613) with Decitabine/Cedazuridine (ASTX727) and Venetoclax (SAVE) in R/R AML

Ghayas C. Issa, Branko Cuglievan, Naval Daver, Courtney D. DiNardo, Aziz Farhat, Nicholas J. Short, David McCall, Allison Pike, Sheila Tan, Brianna Kammerer, Aimee Marshal, Musa Yilmaz, Tapan M. Kadia, Naveen Pemmaraju, Maro Ohanian, Hussein A. Abbas, Abhishek Maiti, Alexandre Bazinet, Elias Jabbour, Koji Sasaki, Gautam Borthakur, Guillermo Montalban-Bravo, Nitin Jain, Yesid Alvarado Valero, Farhad Ravandi, Guillermo Garcia-Manero, Michael Andreeff, Hagop M. Kantarjian
Journal: Blood
Blood (2024) 144 (Supplement 1): 216.
https://doi.org/10.1182/blood-2024-204375
Published: 2024
Journal Articles

FLAG IDA Venetoclax in Newly Diagnosed Pediatric and AYA Patients with AML

Reeja Raj, Samanta Catueno, Amber Gibson, David McCall, Miriam B. Garcia, Cesar Nunez, Michael E. Roth, Koji Sasaki, Priti Tewari, Branko Cuglievan, Courtney D. DiNardo
Journal: Blood
Blood (2024) 144 (Supplement 1): 2906.
https://doi.org/10.1182/blood-2024-211771
Published: 2024
Journal Articles

Identifying ‘Druggable’ Targets and Preclinically Overcoming Non-Genetic/Adaptive Resistance to Menin Inhibitors in AML with MLL1r or mtNPM1

Warren C. Fiskus, Christopher Peter Mill, Jessica Piel, Mike Collins, Murphy Hentemann, Christine Birdwell, Kaberi Das, John A. Davis, Hanxi Hou, Surbhi Sharma, Koji Sasaki, Sanam Loghavi, Branko Cuglievan, Tapan M. Kadia, Naval Daver, Courtney D. DiNardo, Kapil N. Bhalla
Journal: Blood
Blood (2024) 144 (Supplement 1): 1373.
https://doi.org/10.1182/blood-2024-206374
Published: 2024
Journal Articles

APAL2020K/ITCC-101: A Phase I Trial of the Menin Inhibitor Ziftomenib in Combination with Chemotherapy in Children with Relapsed/Refractory KMT2A- rearranged , NUP98- rearranged , or NPM1- mutant Acute Leukemias

Elisabeth Salzer, Janine Stutterheim, Branko Cuglievan, Blake E. Tomkinson, Mollie Leoni, Harm Van Tinteren, Alwin D.R. Huitema, Marieke Willemse, Gwen L Nichols, Francisco Bautista, Sarah K. Tasian, Todd M Cooper, Christian Zwaan
Journal: Blood
Blood (2024) 144 (Supplement 1): 4265.3.
https://doi.org/10.1182/blood-2024-204583
Published: 2024
Journal Articles

Distinct Impact of Platinum Chemotherapies on the Fitness and Genome of Hematopoietic Stem Cells and the Risk of Therapy-Related Myeloid Neoplasms

Jeremy Connors, Linda Zhang, Hidetaka Uryu, Koji Sasaki, Jennifer Padilla, Zongrui Li, Ken Furudate, Tomoyuki Tanaka, Courtney D. DiNardo, Nicholas J. Short, Naval Daver, Gautham Borthakur, Farhad Ravandi, Tapan M. Kadia, Hagop M. Kantarjian, Elias Jabbour, Simona Colla, Branko Cuglievan, Andrew Futreal, Adam S. Sperling, Guillermo Garcia-Manero, Margaret Goodell, Koichi Takahashi
Journal: Blood
Blood (2024) 144 (Supplement 1): 1816.
https://doi.org/10.1182/blood-2024-212052
Published: 2024
Journal Articles

A Phase II Study of the Menin Inhibitor Revumenib in Leukemia Associated with Upregulation of HOX Genes: Trial in Progress

Ghayas C. Issa, Kuo-Kai Chin, James S. Blachly, Aziz Farhat, Lianchun Xiao, Jing Ning, Branko Cuglievan, Neerav Shukla, Koji Sasaki, Sanam Loghavi, Sheng Cai, Hagop M. Kantarjian, Eytan M. Stein
Journal: Blood
Blood (2024) 144 (Supplement 1): 5995.
https://doi.org/10.1182/blood-2024-203466
Published: 2024
Journal Articles

Neighborhood-Level Social Determinants of Health and Cardiovascular Burden in Adolescent and Young Adult Patients Treated for Hodgkin Lymphoma

Elizabeth Rodriguez, Nader Kim El-Mallawany, Sairah Ahmed, Branko Cuglievan, John Andrew Livingston, Christopher R. Flowers, Qian Xiao, Michael E. Roth, Michelle A.T. Hildebrandt
Journal: Blood
Blood (2024) 144 (Supplement 1): 6359.
https://doi.org/10.1182/blood-2024-208944
Published: 2024
Journal Articles

Updated Results and Longer Follow-up from the AUGMENT-101 Phase 2 Study of Revumenib in All Patients with Relapsed or Refractory (R/R) KMT2Ar Acute Leukemia

Ibrahim Aldoss, Ghayas C. Issa, James S. Blachly, Michael J. Thirman, Gabriel N Mannis, Martha L. Arellano, John F. DiPersio, Elie Traer, C. Michel Zwaan, Neerav Shukla, Branko Cuglievan, Carolyn S. Grove, Matthew Greenwood, Christine M. McMahon, Alexander E. Perl, Richard M. Stone, Cristina Papayannidis, David S. Dickens, Maël Heiblig, Andrius Žučenka, Pau Montesinos, Ioannis Mantzaris, Tibor Kovacsovics, Paul J. Shami, Li Yu, Rebecca G. Bagley, Nicole McNeer, Eytan M. Stein
Journal: Blood
Blood (2024) 144 (Supplement 1): 211.
https://doi.org/10.1182/blood-2024-194384
Published: 2024
Journal Articles

Clinical Outcomes Associated with NPM1 Mutations in Newly Diagnosed AML

Aziz Farhat, Hagop M. Kantarjian, Koji Sasaki, Nicholas J. Short, Branko Cuglievan, Sanam Loghavi, Keyur P. Patel, Alex Bataller, Musa Yilmaz, Guillermo Montalban-Bravo, Danielle Hammond, Naveen Pemmaraju, Naval Daver, Farhad Ravandi, Elias Jabbour, Tapan M. Kadia, Gautam Borthakur, Guillermo Garcia-Manero, Courtney D. DiNardo, Ghayas C. Issa
Journal: Blood
Blood (2024) 144 (Supplement 1): 2853.
https://doi.org/10.1182/blood-2024-205504
Published: 2024
Journal Articles

Mortality after Diagnosis of Cardiovascular Disease in Survivors of Adolescent and Young Adult Lymphoma

Karan Gowda, Medha Gupta, Adrian Aguliar, Carlos Cruz, Elizabeth Rodriguez, Sairah Ahmed, Branko Cuglievan, Efstratios Koutroumpakis, Michael E. Roth, Michelle A.T. Hildebrandt
Journal: Blood
Blood (2024) 144 (Supplement 1): 5128.
https://doi.org/10.1182/blood-2024-211291
Published: 2024
Journal Articles

BRG1/BRM inhibitor targets AML stem cells and exerts superior preclinical efficacy combined with BET or menin inhibitor

Warren Fiskus, Jessica Piel, Mike Collins, Murphy Hentemann, Branko Cuglievan, Christopher P. Mill, Christine E. Birdwell, Kaberi Das, John A. Davis, Hanxi Hou, Antrix Jain, Anna Malovannaya, Tapan M. Kadia, Naval Daver, Koji Sasaki, Koichi Takahashi, Danielle Hammond, Patrick K. Reville, Jian Wang, Sanam Loghavi, Rwik Sen, Xinjia Ruan, Xiaoping Su, Lauren B. Flores, Courtney D. DiNardo, Kapil N. Bhalla
Journal: Blood
Blood (2024) 143 (20): 2059–2072.
https://doi.org/10.1182/blood.2023022832
Published: 2024
Includes: Supplemental data
Journal Articles

Revumenib Monotherapy in Patients with Relapsed/Refractory KMT2Ar Acute Leukemia: Topline Efficacy and Safety Results from the Pivotal Augment-101 Phase 2 Study

Ibrahim Aldoss, Ghayas C. Issa, Michael Thirman, John DiPersio, Martha Arellano, James S. Blachly, Gabriel N. Mannis, Alexander Perl, David S. Dickens, Christine M. McMahon, Elie Traer, C. Michel Zwaan, Carolyn Grove, Richard Stone, Paul J. Shami, Ioannis Mantzaris, Matthew Greenwood, Neerav Shukla, Branko Cuglievan, Yu Gu, Rebecca G. Bagley, Kate Madigan, Soujanya Sunkaraneni, Huy Van Nguyen, Nicole McNeer, Eytan M. Stein
Journal: Blood
Blood (2023) 142 (Supplement 2): LBA-5.
https://doi.org/10.1182/blood-2023-192042
Published: 2023
Journal Articles

Targeted Protein Degradation for c-MYC Overcomes Therapy Resistance in T-Cell Acute Lymphoblastic Leukemias

Faryal Munir, Shayaun Khazaei, Phoebe H. Calkins, Darah Scruggs, Hideaki Mizuno, Lauren B. Ostermann, Branko Cuglievan, Miriam B. Garcia, Dong Chen, Youzhi Tong, Zhihua Ren, Michael Andreeff, Yuki Nishida
Journal: Blood
Blood (2023) 142 (Supplement 1): 1447.
https://doi.org/10.1182/blood-2023-187496
Published: 2023
Journal Articles

IFNγ Signaling in Acute Myeloid Leukemia Mediates Immunomodulation and Reveals Therapeutic Strategies

Bofei Wang, Patrick K Reville, Fatima Z Jelloul, Poonam N Desai, Pamella Borges, Christopher Ly, Ivo Veletic, Enes Dasdemir, Jared K. Burks, Guilin Tang, Shengnan Guo, Nicole Vaugh, Natalia Baran, Qing Deng, Jairo Matthews, Preethi Gunaratne, Dinler A Antunes, Suhendan Ekmekcioglu, Koji Sasaki, Miriam B. Garcia, Branko Cuglievan, Dapeng Hao, Naval Daver, Michael R. Green, Marina Y. Konopleva, Andy Futreal, Sean M. Post, Hussein A Abbas
Journal: Blood
Blood (2023) 142 (Supplement 1): 2796.
https://doi.org/10.1182/blood-2023-175010
Published: 2023
Journal Articles

Early Results of the Phase I/II Study Investigating the All-Oral Combination of the Menin Inhibitor Revumenib (SNDX-5613) with Decitabine/Cedazuridine (ASTX727) and Venetoclax in Acute Myeloid Leukemia (SAVE)

Ghayas C. Issa, Branko Cuglievan, Courtney D. DiNardo, Nicholas J. Short, David McCall, Amber Gibson, Cesar Nunez, Miriam B. Garcia, Michael Roth, Aram Bidikian, Allison Pike, Sheila Tan, Brianna Kammerer, Musa Yilmaz, Tapan M. Kadia, Naveen Pemmaraju, Maro Ohanian, Naval Daver, Elias Jabbour, Gautam Borthakur, Farhad Ravandi, Guillermo Garcia-Manero, Michael Andreeff, Hagop M. Kantarjian
Journal: Blood
Blood (2023) 142 (Supplement 1): 58.
https://doi.org/10.1182/blood-2023-182337
Published: 2023
Journal Articles

Revumenib Monotherapy in Patients with Relapsed/Refractory KMT2Ar Acute Leukemias: Efficacy and Safety Results from the Augment-101 Phase 1/2 Study

Ibrahim Aldoss, Ghayas C. Issa, Michael J Thirman, John DiPersio, Martha Arellano, James S. Blachly, Gabriel Mannis, Alexander Perl, David Dickens, Christine M. McMahon, Elie Traer, C. Michel Zwaan, Carolyn Grove, Richard Stone, Paul J Shami, Ioannis Mantzaris, Matthew Greenwood, Neerav Shukla, Branko Cuglievan, Yu Gu, Rebecca G Bagley, Kate Madigan, Soujanya Sunkaraneni, Huy Van Nguyen, Nicole McNeer, Eytan M. Stein
Journal: Blood
Blood (2023) 142 (Supplement 1): 2907.
https://doi.org/10.1182/blood-2023-189762
Published: 2023
Journal Articles

Down Syndrome with Acute Myeloid Leukemia in an Adolescent Male Successfully Treated with Low Dose Ara-C in Combination with Hypomethylating Agent

Ramya Ramakrishnan, Faryal Munir, Andres E Quesada, Sanjit Om Tewari, Branko Cuglievan
Journal: Blood
Blood (2023) 142 (Supplement 1): 5943.
https://doi.org/10.1182/blood-2023-190834
Published: 2023
Journal Articles

“Dose-Dense” Mini-Hyper-CVD, Inotuzumab Ozogamicin and Blinatumomab Achieves High Rates of Rapid MRD-Negativity in Patients with Philadelphia Chromosome-Negative B-Cell Acute Lymphoblastic Leukemia: A Retrospective Analysis

Trevor Jamison, Hagop M. Kantarjian, Shilpa Paul, Branko Cuglievan, David McCall, Nitin Jain, Fadi G. Haddad, Kayleigh R. Marx, Caitlin R Rausch, J. Michael Savoy, Lewis Nasr, Cedric Nasnas, Marianne Zoghbi, Rebecca Garris, Farhad Ravandi, Marina Y. Konopleva, Elias Jabbour, Nicholas J. Short
Journal: Blood
Blood (2023) 142 (Supplement 1): 1508.
https://doi.org/10.1182/blood-2023-188530
Published: 2023