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Michael Dworzak
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Journal Articles

A Reduced Daunorubicin Dose during Induction Is Equally Effective As Standard Dose in Children with Acute Lymphoblastic Leukemia (ALL) and Favorable Prognostic Features: Long-Term Results of the Phase 3 Trial AIEOP-BFM ALL 2009

Martin Schrappe, Hanna Marie Gottschalk, Valentino Conter, Gunnar Cario, Jan Stary, Anja Möricke, Michael Dworzak, Andishe Attarbaschi, Draga Barbaric, Franco Locatelli, Nicole Bodmer, Sarah Elitzur, Daniela Silvestri, Luciano Dalla-Pozza, Bernd Gruhn, Shai Izraeli, Carmelo Rizzari, Jean-Pierre Bourquin, Andrea Biondi, Maria Grazia Valsecchi, Martin Zimmermann
Journal: Blood
Blood (2024) 144 (Supplement 1): 309.
https://doi.org/10.1182/blood-2024-204943
Published: 2024
Journal Articles

Results in Pediatric T-ALL Patients Treated in Trial AIEOP-BFM ALL 2009: Exploring Prognostic Factors in the Context of Modern Risk Adapted Therapy

Gunnar Cario, Maria Grazia Valsecchi, Valentino Conter, Giacomo Gotti, Anja Möricke, Martin Stanulla, Michaela Vossen-Gajcy, Lennart Lenk, Jan Stary, Michael Dworzak, Andishe Attarbaschi, Draga Barbaric, Franco Locatelli, Nicole Bodmer, Sarah Elitzur, Daniela Silvestri, Luciano Dalla-Pozza, Andreas E. Kulozik, Shai Izraeli, Carmelo Rizzari, Barbara Buldini, Jean-Pierre Bourquin, Francesca Graziano, Martin Zimmermann, Martin Schrappe, Andrea Biondi
Journal: Blood
Blood (2024) 144 (Supplement 1): 730.
https://doi.org/10.1182/blood-2024-201936
Published: 2024
Journal Articles

Is the Eutos Long Term Survival (ELTS) Score a Useful Marker to Predict Outcome in Children with Newly Diagnosed Chronic Myeloid Leukemia (CML) in Chronic Phase (CP)? the Experience of the International Registry of Childhood CML

Frederic Millot, Joe De Keizer, Markus Metzler, Meinolf Suttorp, Petr Sedlacek, Maaike Luesink, Frankie WT Cheng, Krzysztof Kalwak, Birgitte Lausen, Gordana Jakovljevic, Barbara De Moerloose, Michael Dworzak, Marina Borisevich, Julia Yajima, Mirella Ampatzidou, Roula Farah, Emilia Kaiserova, Adalet Meral Günes, Andre Baruchel
Journal: Blood
Blood (2023) 142 (Supplement 1): 448.
https://doi.org/10.1182/blood-2023-173810
Published: 2023
Journal Articles

Treatment of Molecular Relapses in Pediatric AML Saves Toxicities Prior to Hematopoietic Stem Cell Transplantation (HSCT) - Results of AMoRe2017 Trial

Amelie Polutta, Dirk Reinhardt, Andre Baruchel, Henrik Hasle, Franco Locatelli, C. Michel Zwaan, Michael Frühwald, Silke Westphal, Michael Dworzak, Heidrun Boztug, Gabriele Escherich, Thomas Lehrnbecher, Bianca F. Goemans, Brigitte Strahm, Markus Schneider, Lina Hoffmeister, Katharina Waack
Journal: Blood
Blood (2023) 142 (Supplement 1): 1521.
https://doi.org/10.1182/blood-2023-180820
Published: 2023
Journal Articles

Treatment Outcomes of Childhood Picalm:MLLT10 + Acute Leukemias: An International Retrospective Study

Catherine Mark, Edward A. Kolb, Bianca F. Goemans, Soheil Meshinchi, Brenda Gibson, Anke K. Bergmann, Christine J. Harrison, Cornelis Jan Pronk, Hélène Lapillonne, Guy Leverger, Evangelia Antoniou, Andishe Attarbaschi, Michael Dworzak, Jan Stary, Daisuke Tomizawa, Monika Lejman, Kjeld Schmiegelow, Henrik Hasle, Brooklyn Joyce, Markus Schneider, Oussama Abla
Journal: Blood
Blood (2022) 140 (Supplement 1): 3403–3404.
https://doi.org/10.1182/blood-2022-156731
Published: 2022
Journal Articles

Transient Monosomy 7 Is a Rare Event in Young Children with SAMD9L Syndrome

Felicia Andresen, Martina Sukova, Jan Stary, Barbara De Moerloose, Jutte Van Der Werff Ten Bosch, Michael Dworzak, Markus G Seidel, Sophia Polychronopoulou, Rita Beier, Christian P. Kratz, Michaela Nathrath, Michael C. Frühwald, Gudrun Göhring, Anke K. Bergmann, Christina Mayerhofer, Natalia Rotari, Dirk Lebrecht, Senthilkumar Ramamoorthy, Ayami Yoshimi, Brigitte Strahm, Marcin W Wlodarski, Charlotte M. Niemeyer, Miriam Erlacher
Journal: Blood
Blood (2022) 140 (Supplement 1): 8678–8679.
https://doi.org/10.1182/blood-2022-159221
Published: 2022
Journal Articles

Association of unbalanced translocation der(1;7) with germline GATA2 mutations

Emilia J. Kozyra, Gudrun Göhring, Dennis D. Hickstein, Katherine R. Calvo, Courtney D. DiNardo, Michael Dworzak, Valerie de Haas, Jan Starý, Henrik Hasle, Akiko Shimamura, Mark D. Fleming, Hiroto Inaba, Sara Lewis, Amy P. Hsu, Steven M. Holland, Danielle E. Arnold, Cristina Mecucci, Siobán B. Keel, Alison A. Bertuch, Kiran Tawana, Shlomit Barzilai, Shinsuke Hirabayashi, Masahiro Onozawa, Shaohua Lei, Helena Alaiz, Hajnalka Andrikovics, David Betts, Berna H. Beverloo, Jochen Buechner, Martin Čermák, José Cervera, Olga Haus, Kirsi Jahnukainen, Kalliopi N. Manola, Karin Nebral, Francesco Pasquali, Joelle Tchinda, Dominik Turkiewicz, Nadine Van Roy, Zuzana Zemanova, Victor B. Pastor, Brigitte Strahm, Peter Noellke, Charlotte M. Niemeyer, Brigitte Schlegelberger, Ayami Yoshimi, Marcin W. Wlodarski
Journal: Blood
Blood (2021) 138 (23): 2441–2445.
https://doi.org/10.1182/blood.2021012781
Published: 2021
Includes: Supplemental data
Journal Articles

Impact of Allogeneic Hematopoietic Stem Cell Transplantation in First Complete Remission and Additional Cytogenetic Aberrations at Diagnosis on Prognosis in 1256 Pediatric Patients with KMT2A-Rearranged Acute Myeloid Leukemia: A Retrospective Study By the I-BFM-SG

Romy E. Van Weelderen, Kim Klein, Christine J. Harrison, Hester A. De Groot-Kruseman, Jonas Abrahamsson, Nira Arad-Cohen, Emmanuelle Bart-Delabesse, Barbara Buldini, Barbara De Moerloose, Michael Dworzak, Sarah Elitzur, José M. Fernández Navarro, Marta Fiocco, Robert B. Gerbing, Bianca F. Goemans, Erin Guest, Shau-Yin Ha, Henrik Hasle, Kathy Jackson, Charikleia Kelaidi, Hélène Lapillonne, Guy Leverger, Franco Locatelli, Takako Miyamura, Sophia Polychronopoulou, Mareike Rasche, Jeffrey E. Rubnitz, Jan Stary, Daisuke Tomizawa, Femke Verwer, C. Michel Zwaan, Gertjan J.L. Kaspers
Journal: Blood
Blood (2021) 138 (Supplement 1): 2360.
https://doi.org/10.1182/blood-2021-148041
Published: 2021
Journal Articles

Outcome of (Novel) Subgroups in 1257 Pediatric Patients with KMT2A-Rearranged Acute Myeloid Leukemia (AML) and the Significance of Minimal Residual Disease (MRD) Status: A Retrospective Study By the I-BFM-SG

Romy E. Van Weelderen, Kim Klein, MD, Bianca F. Goemans, MD PhD, Christian M. Zwaan, MD PhD, Hester A. De Groot-Kruseman, PhD, Jonas Abrahamsson, MD PhD, Nira Arad-Cohen, MD PhD, Emmanuelle Bart-Delabesse, PharmD, PhD, Barbara Buldini, MD PhD, Barbara De Moerloose, MD PhD, Michael Dworzak, MD PhD, Sarah Elitzur, MD, José M. Fernández Navarro, MD, Robert B. Gerbing, MA, Erin Guest, MD, Shau-Yin Ha, MD PhD, Christine J. Harrison, PhD FRCPath, Henrik Hasle, PhD, Kathy Jackson, MD PhD, Charikleia Kelaidi, MD, Hélène Lapillonne, MD PhD, Guy Leverger, MD PhD, Franco Locatelli, MD PhD, Takako Miyamura, MD PhD, Sophia Polychronopoulou, MD PhD, Mareike Rasche, MD, Jeffrey E. Rubnitz, MD, Jan Stary, MD PhD, Daisuke Tomizawa, MD PhD, Femke Verwer, Gertjan J.L. Kaspers, Prof. MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 26–27.
https://doi.org/10.1182/blood-2020-136064
Published: 2020
Journal Articles

NF1 Tumor Suppressor Gene Inactivation in Juvenile Myelomonocytic Leukemia: New Genetic Evidence and Consequences for Diagnostic Work-up

Senthilkumar Ramamoorthy, PhD, Dirk Lebrecht, PhD, Denny Schanze, PhD, Ina Schanze, MD, Ilse Wieland, PhD, Michael H. Albert, MD, Arndt Borkhardt, MD, Dorine Bresters, MD PhD, Jochen Büchner, MDPhD, Albert Catala, MD PhD, Valerie De Haas, MD PhD, Michael Dworzak, MD PhD, Miriam Erlacher, MD PhD, Henrik Hasle, PhD, Kirsi Jahnukainen, MD PhD, Franco Locatelli, MD PhD, Riccardo Masetti, MDPhD, Jan Stary, MD PhD, Dominik Turkiewicz, MD, Luca Vinci, MD, Marcin W. Wlodarski, MD PhD, Ayami Yoshimi, MD PhD, Maria Hess, Melanie Boerries, MD PhD, Charlotte M. Niemeyer, MD, Martin Zenker, MD, Christian Flotho, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 30–31.
https://doi.org/10.1182/blood-2020-136294
Published: 2020
Journal Articles

Failures and Successes in Pediatric Patients with Acute Myeloid Leukemia with First Relapse: A Large International Report on Current Treatment Strategies and Outcome

Mareike Rasche, MD, Martin Zimmermann, Emma Steidel, Todd A. Alonzo, PhD, Richard Aplenc, MD PhD, Jean-Pierre Bourquin, MD PhD, Heidrun Boztug, Alan S. Gamis, MD MPH, Robert B. Gerbing, MA, Iveta Janotová, Thomas Lehrnbecher, Nora Muehlegger, Nils Von Neuhoff, PhD, Naghmeh Niktoreh, Lucie Sramkova, MD, Jan Stary, MD PhD, Christiane Walter, MSc, Ursula Creutzig, MD PhD, Michael Dworzak, MD PhD, Edward A. Kolb, MD, Dirk Reinhardt, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 6–7.
https://doi.org/10.1182/blood-2020-141774
Published: 2020
Journal Articles

Improved Outcome in Pediatric AML - the AML-BFM 2012 Study

Katharina Waack, Markus Schneider, PhD, Christiane Walter, MSc, Ursula Creutzig, MD, Jan-Henning Klusmann, Mareike Rasche, MD, Heidrun Boztug, Katharina Jansen, PhD, Gabriele Escherich, MD, Michael Frühwald, MD, Michael Dworzak, MD PhD, Dirk Reinhardt, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 12–14.
https://doi.org/10.1182/blood-2020-139189
Published: 2020
Journal Articles

Second Relapse of Pediatric Patients with Acute Myeloid Leukemia: A Report on Current Treatment Strategies and Outcome of the AML-BFM Study Group

Mareike Rasche, MD, Emma Steidel, Martin Zimmermann, Jean-Pierre Bourquin, MD PhD, Heidrun Boztug, Iveta Janotová, Edward A. Kolb, MD, Thomas Lehrnbecher, Nils Von Neuhoff, PhD, Naghmeh Niktoreh, Nora Muehlegger, Lucie Sramkova, MD, Jan Stary, MD PhD, Christiane Walter, MSc, Ursula Creutzig, MD PhD, Michael Dworzak, MD PhD, Dirk Reinhardt, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 24.
https://doi.org/10.1182/blood-2020-139317
Published: 2020
Journal Articles

Outcome of Allogeneic Hematopoietic Stem Cell Transplantation in Children and Adolescents with GATA2-Related Myelodysplastic Syndrome

Rachel Bortnick, MD PhD, Marcin Wlodarski, Valerie de Haas, MD PhD, Barbara De Moerloose, MD PhD, Michael Dworzak, MD, Henrik Hasle, Riccardo Masetti, MD PhD, Jan Stary, Prof., MD PhD, Dominik Turkiewicz, MD, Marek Ussowicz, MD, Michael H. Albert, MD, Peter Bader, MD, Victoria Bordon, MD PhD, Alexander Claviez, MD, Bernhard Kremens, MD PhD, Jörn Sven Kühl, MD, Arjan C. Lankester, MD PhD, Ingo Müller, MD, Herbert Pichler, MD, Petr Sedlacek, MD, Karl-Walter Sykora, MD, Marco Zecca, MD, Gudrun Göhring, MD, Franco Locatelli, MD PhD, Peter Noellke, MPH, Charlotte M. Niemeyer, MD, Brigitte Strahm, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2033.
https://doi.org/10.1182/blood-2019-122403
Published: 2019
Journal Articles

Transient Switch to Myeloid Lineage in Acute Lymphoblastic Leukemia during Induction Therapy: The Role of CD371 Expression and Implication for Minimal Residual Disease Detection

Elena Varotto, MD PhD, Margarita Maurer-Granofszky, PhD, Daniela Silvestri, Pamela Scarparo, PhD, Ester Mejstrikova, MD PhD, Monika Brüggemann, Giovanni Cazzaniga, PhD, Valentino Conter, MD, Ondrej Hrusak, MD PhD, Giuseppe Gaipa, PhD, Angela Schumich, Maria Grazia Valsecchi, PhD, Giuseppe Basso, MD PhD, Michael Dworzak, MD, Barbara Buldini, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 377.
https://doi.org/10.1182/blood-2019-127287
Published: 2019
Journal Articles

Impact of a Risk-Adapted Treatment Approach in Pediatric AML: A Report of the AML-BFM Registry 2012

Mareike Rasche, MD, Emma Steidel, Denise Kondryn, Nils Von Neuhoff, PhD, Lucie Sramkova, MD, Ursula Creutzig, MD, Michael Dworzak, MD, Dirk Reinhardt, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 293.
https://doi.org/10.1182/blood-2019-130969
Published: 2019
Journal Articles

SAMD9 and SAMD9L Germline Disorders in Patients Enrolled in Studies of the European Working Group of MDS in Childhood (EWOG-MDS): Prevalence, Outcome, Phenotype and Functional Characterisation

Sushree Sangita Sahoo, MSc, Victor Pastor Loyola, MSc, Pritam Kumar Panda, MSc, MS, BSc, Enikoe Amina Szvetnik, Emilia J. Kozyra, MSc, Rebecca K Voss, MD, Dirk Lebrecht, PhD, Shlomit Barzilai, MD, Jochen Büchner, MDPhD, Albert Catala, MD PhD, Barbara De Moerloose, MD PhD, Michael Dworzak, MD, Oksana Fabri, MD, Henrik Hasle, MD, Kirsi Jahnukainen, Krisztián Kállay, MD, Franco Locatelli, Riccardo Masetti, MDPhD, Sophia Polychronopoulou, MD PhD, Markus Schmugge, MD, Jan Stary, MD PhD, Owen P Smith, MD, Dominik Turkiewicz, Marek Ussowicz, Marry M. van den Heuvel-Eibrink, Prof, Peter Noellke, MPH, Gudrun Göhring, MD, Miriam Erlacher, MD PhD, Christian Flotho, Brigitte Strahm, PD Dr., Charlotte Niemeyer, MD, Marcin W. Wlodarski, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 643.
https://doi.org/10.1182/blood-2018-99-118389
Published: 2018
Journal Articles

Features and Outcome of Chronic Myeloid Leukemia (CML) at Very Young Age: Data from the International Pediatric CML Registry (I-CML-Ped Study)

Adalet Meral Gunes, Frédéric Millot, MD, Krzysztof Kalwak, MD, Birgitte Lausen, MD PhD, Petr Sedlacek, MD, Birgitte Versluijs, Michael Dworzak, MD, Barbara De Moerloose, MD PhD, Meinolf Suttorp, PhD MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1748.
https://doi.org/10.1182/blood-2018-99-112905
Published: 2018
Journal Articles

Prognostic impact of t(16;21)(p11;q22) and t(16;21)(q24;q22) in pediatric AML: a retrospective study by the I-BFM Study Group

Clinical Trials & Observations
Sanne Noort, Martin Zimmermann, Dirk Reinhardt, Wendy Cuccuini, Martina Pigazzi, Jenny Smith, Rhonda E. Ries, Todd A. Alonzo, Betsy Hirsch, Daisuke Tomizawa, Franco Locatelli, Tanja A. Gruber, Susana Raimondi, Edwin Sonneveld, Daniel K. Cheuk, Michael Dworzak, Jan Stary, Jonas Abrahamsson, Nira Arad-Cohen, Malgorzata Czogala, Barbara De Moerloose, Henrik Hasle, Soheil Meshinchi, Marry van den Heuvel-Eibrink, C. Michel Zwaan
Journal: Blood
Blood (2018) 132 (15): 1584–1592.
https://doi.org/10.1182/blood-2018-05-849059
Published: 2018
Includes: Supplemental data
Journal Articles

International cooperative study identifies treatment strategy in childhood ambiguous lineage leukemia

CME Clinical Trials & Observations
Ondrej Hrusak, Valerie de Haas, Jitka Stancikova, Barbora Vakrmanova, Iveta Janotova, Ester Mejstrikova, Vaclav Capek, Jan Trka, Marketa Zaliova, Ales Luks, Kirsten Bleckmann, Anja Möricke, Julie Irving, Benigna Konatkowska, Thomas B. Alexander, Hiroto Inaba, Kjeld Schmiegelow, Simone Stokley, Zuzana Zemanova, Anthony V. Moorman, Jorge Gabriel Rossi, Maria Sara Felice, Luciano Dalla-Pozza, Jessa Morales, Michael Dworzak, Barbara Buldini, Giuseppe Basso, Myriam Campbell, Maria Elena Cabrera, Neda Marinov, Sarah Elitzur, Shai Izraeli, Drorit Luria, Tamar Feuerstein, Alexandra Kolenova, Peter Svec, Olena Kreminska, Karen R. Rabin, Sophia Polychronopoulou, Elaine da Costa, Hanne Vibeke Marquart, Antonis Kattamis, Richard Ratei, Dirk Reinhardt, John K. Choi, Martin Schrappe, Jan Stary
Journal: Blood
Blood (2018) 132 (3): 264–276.
https://doi.org/10.1182/blood-2017-12-821363
Published: 2018
Includes: Supplemental data