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Hester A. De Groot-Kruseman
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Journal Articles

Tyrosine kinase inhibitor response of ABL-class acute lymphoblastic leukemia: the role of kinase type and SH3 domain

Inge van Outersterp, Sarah K. Tasian, Caitlin E. J. Reichert, Aurélie Boeree, Hester A. de Groot-Kruseman, Gabriele Escherich, Judith M. Boer, Monique L. den Boer
Journal: Blood
Blood (2024) 143 (21): 2178–2189.
https://doi.org/10.1182/blood.2023023120
Published: 2024
Includes: Supplemental data
Journal Articles

Novel Insights in TKI Resistance in BCR :: ABL1 -Positive B-Cell Acute Lymphoblastic Leukemia Beyond Kinase Domain Mutations

Inge Van Outersterp, Caitlin E.J. Reichert, Aurelie Boeree, Cesca Van De Ven, Brian Kruisinga, Hester A. de Groot-Kruseman, Gabriele Escherich, Anita W. Rijneveld, Judith M. Boer, Monique L. den Boer
Journal: Blood
Blood (2023) 142 (Supplement 1): 1615.
https://doi.org/10.1182/blood-2023-179704
Published: 2023
Journal Articles

STAG2/LMO2 Gamma-Delta (γδ) T-ALL: Identification and Characterization of an Extremely High Risk Group of T-ALL in the Very Young

Shunsuke Kimura, Petri Pölönen, Lindsey Montefiori, Kenneth Caldwell, Ilaria Iacobucci, Chelsey Chen, Anthony Brown, Katie Han, Yen-Chun Liu, Yunchao Chang, Zhongshan Cheng, Zhou Yinmei, Chun Shik Park, Sharnise Mitchell, Noemi Reyes, Allen Yeoh, Andishe Attarbaschi, Andrew Moore, Atsushi Manabe, Barbara Buldini, Kean Hui Chiew, Chi Kong Li, Ching-Hon Pui, Chunxu Qu, Daisuke Tomizawa, Elisabeth Paietta, Franco Locatelli, Gabriele Escherich, Gao Qingsong, Hannah Elisa Muhle, Hanne Vibeke Marquart, Hester A. de Groot-Kruseman, Jacob M. Rowe, Jan Stary, Jan Trka, John Kim Choi, Jules P.P. Meijerink, Junko Takita, Katarzyna Pawinska-Wasikowska, Kjeld Schmiegelow, Mariko Eguchi, Martin Schrappe, Martin Zimmermann, Masatoshi Takagi, Melissa Maybury, Michael Svaton, Michaela Reiterova, Michal Kicinski, Motohiro Kato, Orietta Spinelli, Pauline Mazilier, Paul G. Thomas, Riccardo Masetti, Rishi Sury Kotecha, Rob Pieters, Sarah Elitzur, Selina M Luger, Shuhong Shen, Sima Jeha, Steven M. Kornblau, Szymon Skoczen, Takako Miyamura, Tiffaney Vincent, Toshihiko Imamura, Valentino Conter, Yanjing Tang, Zhaohui Gu, Kathryn G. Roberts, David T. Teachey, Kristine R Crews, Cheng Cheng, Jun J. Yang, Hiroto Inaba, Charles G. Mullighan
Journal: Blood
Blood (2023) 142 (Supplement 1): 845.
https://doi.org/10.1182/blood-2023-178688
Published: 2023
Journal Articles

Spatial Technologies Reveal the Immune Landscape of Pediatric Acute Myeloid Leukemia

Joost B. Koedijk, Inge Van Der Werf, Marijn A. Vermeulen, Alicia Perzolli, Marta F. Fiocco, Hester A. de Groot-Kruseman, Rubina Moeniralam, Kristina B. Christensen, Henrik Hasle, Stefan Nierkens, Mirjam E. Belderbos, Michel C. Zwaan, Olaf Heidenreich
Journal: Blood
Blood (2023) 142 (Supplement 1): 2959.
https://doi.org/10.1182/blood-2023-177932
Published: 2023
Journal Articles

The Effect of Immunoglobulin Prophylaxis on Infectious Morbidity in Pediatric Patients with Acute Lymphoblastic Leukemia: Results of a Randomized Controlled Trial

Kirsten Thus, Hester A. de Groot-Kruseman, Pauline Winkler-Seinstra, Heidi Segers, Cor van den Bos, Inge M. Van Der Sluis, Wim Tissing, Margreet A. Veening, Michel C. Zwaan, Marta F. Fiocco, Cornelis van Tilburg, Rob Pieters, Marc Bierings
Journal: Blood
Blood (2023) 142 (Supplement 1): 2839.
https://doi.org/10.1182/blood-2023-173418
Published: 2023
Journal Articles

Implementation of Continuous Pegasparaginase Dosing without an Asparaginase-Free Interval Reduces Hypersensitivity in Children with Newly Diagnosed Acute Lymphoblastic Leukemia: Results of the DCOG ALL11 Pegasparaginase Randomization

Leiah J. Brigitha, Rob Pieters, Marta F. Fiocco, Hester A. de Groot-Kruseman, Marc Bierings, Cor Van Den Bos, Valerie de Haas, Peter M. Hoogerbrugge, Wim J.E. Tissing, Margreet A. Veening, Inge M. Van Der Sluis
Journal: Blood
Blood (2023) 142 (Supplement 1): 2883.
https://doi.org/10.1182/blood-2023-173359
Published: 2023
Journal Articles

Dutch ALL11 Study: Improved Outcome for Acute Lymphoblastic Leukemia By Prolonging Therapy for IKZF1 Deletion and Decreasing Therapy for ETV6::RUNX1, Down Syndrome and Prednisone Poor Responders

Rob Pieters, Hester A. De Groot-Kruseman, Femke Verwer, Merian van Overveld, Edwin Sonneveld, Marta Fiocco, Vincent H.J. van der Velden, Berna Beverloo, Marc Bierings, Valerie De Haas, Peter M. Hoogerbrugge, Inge M. Van Der Sluis, Wim J.E. Tissing, Margreet Veening, Judith M. Boer, Monique L. den Boer
Journal: Blood
Blood (2022) 140 (Supplement 1): 519–520.
https://doi.org/10.1182/blood-2022-165931
Published: 2022
Journal Articles

Impact of Allogeneic Hematopoietic Stem Cell Transplantation in First Complete Remission and Additional Cytogenetic Aberrations at Diagnosis on Prognosis in 1256 Pediatric Patients with KMT2A-Rearranged Acute Myeloid Leukemia: A Retrospective Study By the I-BFM-SG

Romy E. Van Weelderen, Kim Klein, Christine J. Harrison, Hester A. De Groot-Kruseman, Jonas Abrahamsson, Nira Arad-Cohen, Emmanuelle Bart-Delabesse, Barbara Buldini, Barbara De Moerloose, Michael Dworzak, Sarah Elitzur, José M. Fernández Navarro, Marta Fiocco, Robert B. Gerbing, Bianca F. Goemans, Erin Guest, Shau-Yin Ha, Henrik Hasle, Kathy Jackson, Charikleia Kelaidi, Hélène Lapillonne, Guy Leverger, Franco Locatelli, Takako Miyamura, Sophia Polychronopoulou, Mareike Rasche, Jeffrey E. Rubnitz, Jan Stary, Daisuke Tomizawa, Femke Verwer, C. Michel Zwaan, Gertjan J.L. Kaspers
Journal: Blood
Blood (2021) 138 (Supplement 1): 2360.
https://doi.org/10.1182/blood-2021-148041
Published: 2021
Journal Articles

A Validated Risk Prediction Model for Bone Fragility in Children with Acute Lymphoblastic Leukemia

Emma Jacobine Verwaaijen, Jinhui Ma, Hester A. De Groot-Kruseman, Rob Pieters, Inge M. Van Der Sluis, Jenneke E. Van Atteveld, Jacqueline Halton, Conrad Fernandez, Annelies Hartman, Robert de Jonge, Maarten Lequin, Mariël L. te Winkel, Stephanie A. Atkinson, Nathalie Alos, Ronald Barr, Ronald M. Grant, John Hay, Adam Huber, Josephine Ho, Jacob Jaremko, Khaldoun Koujok, Bianca Lang, Mary-Ann Matzinger, Nazih Shenouda, Frank Rauch, Celia Rodd, Marry M. van den Heuvel-Eibrink, Saskia M.F. Pluijm, Leanne Ward
Journal: Blood
Blood (2021) 138 (Supplement 1): 3359.
https://doi.org/10.1182/blood-2021-146838
Published: 2021
Journal Articles

Outcome of (Novel) Subgroups in 1257 Pediatric Patients with KMT2A-Rearranged Acute Myeloid Leukemia (AML) and the Significance of Minimal Residual Disease (MRD) Status: A Retrospective Study By the I-BFM-SG

Romy E. Van Weelderen, Kim Klein, MD, Bianca F. Goemans, MD PhD, Christian M. Zwaan, MD PhD, Hester A. De Groot-Kruseman, PhD, Jonas Abrahamsson, MD PhD, Nira Arad-Cohen, MD PhD, Emmanuelle Bart-Delabesse, PharmD, PhD, Barbara Buldini, MD PhD, Barbara De Moerloose, MD PhD, Michael Dworzak, MD PhD, Sarah Elitzur, MD, José M. Fernández Navarro, MD, Robert B. Gerbing, MA, Erin Guest, MD, Shau-Yin Ha, MD PhD, Christine J. Harrison, PhD FRCPath, Henrik Hasle, PhD, Kathy Jackson, MD PhD, Charikleia Kelaidi, MD, Hélène Lapillonne, MD PhD, Guy Leverger, MD PhD, Franco Locatelli, MD PhD, Takako Miyamura, MD PhD, Sophia Polychronopoulou, MD PhD, Mareike Rasche, MD, Jeffrey E. Rubnitz, MD, Jan Stary, MD PhD, Daisuke Tomizawa, MD PhD, Femke Verwer, Gertjan J.L. Kaspers, Prof. MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 26–27.
https://doi.org/10.1182/blood-2020-136064
Published: 2020
Journal Articles

A validated novel continuous prognostic index to deliver stratified medicine in pediatric acute lymphoblastic leukemia

Clinical Trials & Observations
Amir Enshaei, David O’Connor, Jack Bartram, Jeremy Hancock, Christine J. Harrison, Rachael Hough, Sujith Samarasinghe, Monique L. den Boer, Judith M. Boer, Hester A. de Groot-Kruseman, Hanne V. Marquart, Ulrika Noren-Nystrom, Kjeld Schmiegelow, Claire Schwab, Martin A. Horstmann, Gabriele Escherich, Mats Heyman, Rob Pieters, Ajay Vora, John Moppett, Anthony V. Moorman
Journal: Blood
Blood (2020) 135 (17): 1438–1446.
https://doi.org/10.1182/blood.2019003191
Published: 2020
Includes: Supplemental data
Journal Articles

Minimal Residual Disease and IKZF1 As Predictors of Relapse, and Increased Treatment Related Mortality in Down Syndrome Acute Lymphoblastic Leukemia: A Unique and Large International Matched Case-Control Study

Naomi Michels, BSc, Judith M. Boer, PhD, Marta Lopez-Yurda, PhD, Hester A. De Groot-Kruseman, PhD, Vincent van der Velden, PhD, Anthony V. Moorman, Amir Enshaei, PhD, Ajay Vora, Rosemary Sutton, BSc MSc PhD, Toby Trahair, PhD, Luciano Dalla-Pozza, MBBS FRACP, Rob Pieters, MDPhDMSc, Michel C Zwaan, MD PhD, Monique L. Den Boer, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 827.
https://doi.org/10.1182/blood-2019-124290
Published: 2019
Journal Articles

JAK2 Aberrations in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia

Elisabeth M.P. Steeghs, MSc, Isabel S. Jerchel, MSc, Willemieke de Goffau-Nobel, MSc, Alex Q. Hoogkamer, BSc, Judith M. Boer, PhD, Aurélie Boeree, BSc, Cesca van de Ven, PhD, Marco J. Koudijs, PhD, Nicolle J.M. Besselink, BSc, Hester A. de Groot-Kruseman, PhD, C. Michel Zwaan, MD PhD, Martin A. Horstmann, MD, Rob Pieters, MD PhD, Monique L. Den Boer, PhD
Journal: Blood
Blood (2016) 128 (22): 583.
https://doi.org/10.1182/blood.V128.22.583.583
Published: 2016
Journal Articles

RAS Pathway Mutations As Predictive Biomarker for Treatment Adaptation in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia

Isabel S. Jerchel, MSc, Alex Q. Hoogkamer, BSc, Ingrid M. Ariës, PhD, Elisabeth M.P. Steeghs, MSc, Judith M. Boer, PhD, Nicolle J.M. Besselink, BSc, Aurélie Boeree, BSc, Cesca van de Ven, PhD, Hester A. de Groot-Kruseman, PhD, Valerie De Haas, MD PhD, Martin A. Horstmann, MD, Gabriele Escherich, MD, Ronald W. Stam, PhD, C. Michel Zwaan, MD PhD, Edwin Cuppen, PhD, Marco J. Koudijs, PhD, Rob Pieters, MD PhD, Monique L. Den Boer, MSc, PhD
Journal: Blood
Blood (2016) 128 (22): 4087.
https://doi.org/10.1182/blood.V128.22.4087.4087
Published: 2016
Journal Articles

Clinical Relevance of Tyrosine Kinase Fusion Genes in Pediatric BCR-ABL1 -like Acute Lymphoblastic Leukemia

Judith M. Boer, PhD, Aurélie Boeree, BSc, João R.M. Marchante, MSc, Berna Beverloo, PhD, Gabriele Escherich, MD, Hester A. de Groot-Kruseman, PhD, Rob Pieters, MD PhD, Monique L. Den Boer, PhD
Journal: Blood
Blood (2015) 126 (23): 3735.
https://doi.org/10.1182/blood.V126.23.3735.3735
Published: 2015
Journal Articles

Aggravated Bone Density Decline after Symptomatic Osteonecrosis in Children with Acute Lymphoblastic Leukemia

Marissa den Hoed, S.M.F. Pluijm, Mariël L. Te Winkel, Hester A. de Groot-Kruseman, PhD, Marta Fiocco, PhD, Peter M. Hoogerbrugge, MD PhD, J.a. Leeuw, Marrie Bruin, MD PhD, Inge M. van der Sluis, MD PhD, Dorine Bresters, MD PhD, Maarten H. Lequin, MD PhD, Jan C. Roos, A. Veerman, MD PhD, Rob Pieters, Marry M. van den Heuvel-Eibrink
Journal: Blood
Blood (2014) 124 (21): 2260.
https://doi.org/10.1182/blood.V124.21.2260.2260
Published: 2014
Journal Articles

The Negative Impact of Underweight and Weight Loss on Survival of Children with Acute Lymphoblastic Leukemia

Marissa den Hoed, S.M.F. Pluijm, Hester A. de Groot-Kruseman, PhD, Mariël L. Te Winkel, Erica L.T. van den Akker, MD PhD, Peter M. Hoogerbrugge, MD PhD, Henk van den Berg, MD, J.a. Leeuw, Marrie Bruin, MD PhD, Dorine Bresters, MD PhD, A.J.P. Veerman, MD PhD, Marta Fiocco, PhD, Rob Pieters, MD PhD, Marry M. van den Heuvel-Eibrink
Journal: Blood
Blood (2014) 124 (21): 2261.
https://doi.org/10.1182/blood.V124.21.2261.2261
Published: 2014
Journal Articles

Toxicity of Very Prolonged Pegasparaginase and Erwinia Asparaginase Courses in Relation to Asparaginase Activity Levels with a Special Focus on Dyslipidemia

Wing H. Tong, MD PhD, Rob Pieters, Hester A. de Groot-Kruseman, PhD, Wim C.J. Hop, PhD, Joachim Boos, MD PhD, Wim J Tissing, MD PhD, Inge M. van der Sluis, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2256.
https://doi.org/10.1182/blood.V124.21.2256.2256
Published: 2014
Journal Articles

Prognostic Value of Rare IKZF1 deletions in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia: An International Collaborative Study

Judith M. Boer, PhD, Arian van der Veer, MD PhD, Dimitris Rizopoulos, PhD, Marta Fiocco, PhD, Edwin Sonneveld, PhD, Hester A. de Groot-Kruseman, PhD, Roland P. Kuiper, PhD, Peter M. Hoogerbrugge, MD PhD, Martin A. Horstmann, MD PhD, Marketa Zaliova, MD PhD, Chiara Palmi, Jan Trka, MD, PhD, Prof., Eva Fronkova, MD, PhD, Mariana Emerenciano, PhD, Maria do Socorro Pombo-de-Oliveira, PhD, Wojciech Mlynarski, MDPhD, Tomasz Szczepanski, MD PhD, Karin Nebral, PhD, Andishe Attarbaschi, MD PhD, Nicola C. Venn, PhD, Rosemary Sutton, PhD, Claire Schwab, BSc, Amir Enshaei, PhD, Ajay J. Vora, Martin Stanulla, MD, Martin Schrappe, MD, Gianni Cazzaniga, PhD, Valentino Conter, MD PhD, Martin Zimmerman, PhD, Anthony V. Moorman, PhD, Rob Pieters, Monique L. Den Boer, MSc, PhD
Journal: Blood
Blood (2014) 124 (21): 368.
https://doi.org/10.1182/blood.V124.21.368.368
Published: 2014
Journal Articles

Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL

Arian van der Veer, Esmé Waanders, Rob Pieters, Marieke E. Willemse, Simon V. Van Reijmersdal, Lisa J. Russell, Christine J. Harrison, William E. Evans, Vincent H. J. van der Velden, Peter M. Hoogerbrugge, Frank Van Leeuwen, Gabriele Escherich, Martin A. Horstmann, Leila Mohammadi Khankahdani, Dimitris Rizopoulos, Hester A. De Groot-Kruseman, Edwin Sonneveld, Roland P. Kuiper, Monique L. Den Boer
Journal: Blood
Blood (2013) 122 (15): 2622–2629.
https://doi.org/10.1182/blood-2012-10-462358
Published: 2013
Includes: Supplemental data