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Journal Articles

Measurable Residual Disease Monitoring during Treatment for Pediatric Acute Myeloid Leukemia in First Relapse Predicts Outcome

Camilla Poulsen, Kristian Juul Sandahl, Lene Karlsson, Jonas Abrahamsson, Nira Arad-Cohen, Daniel Cheuk, Barbara De Moerloose, Jose Maria Fernandez Navarro, Kirsi Jahnukainen, Gertjan J.L. Kaspers, Zhanna Kovalova, Monica Cheng Munthe-Kaas, Ulrika Norén-Nyström, Josefine Palle, Ramune Pasauliene, Cornelis Jan Pronk, Kadri Saks, Kristian Juul-Dam, Henrik Hasle

Blood (2024) 144 (Supplement 1): 323.

https://doi.org/10.1182/blood-2024-193741

Published: 2024

Journal Articles

Comparison of the WHO and ICC Classifications of Cytogenetic Abnormalities in Childhood Acute Myeloid Leukemia

Blood (2024) 144 (Supplement 1): 322.

https://doi.org/10.1182/blood-2024-193878

Published: 2024

Journal Articles

Early Peripheral Blood Blast Clearance As a Prognostic Marker for Early Treatment Response in Pediatric Acute Myeloid Leukemia

Noa E. Wijnen, Bianca de Boer, Kim Klein, Jonas Abrahamsson, Barbara De Moerloose, Bernward Zeller, Henrik Hasle, Zhanna Kovalova, Nira Arad-Cohen, Gertjan J.L. Kaspers

Blood (2023) 142 (Supplement 1): 2950.

https://doi.org/10.1182/blood-2023-185597

Published: 2023

Journal Articles

Management of Hyperleukocytosis in Pediatric Acute Myeloid Leukemia Using Immediate Chemotherapy without Leukapheresis, in Protocol NOPHO-DBH AML-2012

Bernward Zeller, Nira Arad-Cohen, Daniel Cheuk, Barbara De Moerloose, Jose Maria Fernandez Navarro, Henrik Hasle, Jahnukainen Kirsi, Kristian Juul-Dam, Gertjan J.L. Kaspers, Zhanna Kovalova, Birgitte Lausen, Monica C. Munthe-Kaas, Ulrika Norén-Nyström, Josefine Palle, Ramune Pasauliene, Cornelis Jan Pronk, Kadri Saks, Anne Maria Tierens, Jonas Abrahamsson

Blood (2023) 142 (Supplement 1): 2852.

https://doi.org/10.1182/blood-2023-184921

Published: 2023

Journal Articles

Chip-AML22 Master Protocol: An Open-Label Clinical Trial in Newly Diagnosed Pediatric De Novo Acute Myeloid Leukemia (AML) Patients Including a Linked Phase II Trial with Quizartinib in FLT3 -ITD/ NPM1 wt Patients - a Study By the NOPHO-DB-SHIP Consortium

Blood (2023) 142 (Supplement 1): 1532.

https://doi.org/10.1182/blood-2023-181792

Published: 2023

Journal Articles

A Randomized Comparison of Liposomal Daunorubicin/Daunorubicin Combined with Low-Dose Cytarabine and Etoposide or High-Dose Cytarabine and Fludarabine in Induction Treatment of Pediatric AML Using MRD-Based Risk Stratification in the NOPHO-DBH AML 2012 Protocol

Barbara De Moerloose, Nira Arad-Cohen, Daniel Cheuk, Jose Maria Fernandez Navarro, Henrik Hasle, Kirsi Jahnukainen, Gertjan J.L. Kaspers, Zhanna Kovalova, Birgitte Lausen, Ulrika Norén-Nyström, Josefine Palle, Ramune Pasauliene, Cornelis Jan Pronk, Kadri Saks, Anne Maria Tierens, Bernward Zeller, Jonas Abrahamsson

Blood (2023) 142 (Supplement 1): 831.

https://doi.org/10.1182/blood-2023-187251

Published: 2023

Journal Articles

Decreased Embryonic Splicing Repressor Expression Enhances Splicing Modulator Sensitivity in Pediatric Acute Myeloid Leukemia Stem Cells

Inge Van Der Werf, Kathleen Steel, Phoebe Mondala, Larissa Balaian, Jacqueline Cloos, Gertjan J.L. Kaspers, James La Clair, Peggy Wentworth, Kathleen Fisch, Leslie Crews, Thomas Whisenant, Michael Burkart, Mary Donohoe, Catriona Jamieson

Blood (2022) 140 (Supplement 1): 3354–3355.

https://doi.org/10.1182/blood-2022-171145

Published: 2022

Journal Articles

High Immunoproteasome Expression As Indicator for Sensitivity to Bortezomib-Containing Chemotherapy in Newly Diagnosed, Standard and Intermediate Risk, T-Cell Acute Lymphoblastic Leukemia Patients from Children's Oncology Group Trial AALL1231

Margot S.F. Roeten, Johan van Meerloo, Zinia Kwidama, Gaye Jenkins, Suzanne N. van Dijk, David T. Teachey, Meenakshi Devidas, Mignon L. Loh, Gertjan J.L. Kaspers, Sonja Zweegman, Gerrit Jansen, Jacqueline Cloos, Terzah M. Horton

Blood (2022) 140 (Supplement 1): 9183–9184.

https://doi.org/10.1182/blood-2022-162412

Published: 2022

Journal Articles

Non-Infectious Morbidity during Pediatric Acute Myeloid Leukemia Chemotherapy in the Netherlands: A 15-Year Overview

Emily R. Schwartz, Kim Klein, Valerie De Haas, Natasja Dors, Marry M. van den Heuvel-Eibrink, Rutger R.G. Knops, Wim J.E. Tissing, Birgitta Versluijs, C. Michel Zwaan, Raphaele R.L. van Litsenburg, Gertjan J.L. Kaspers

Blood (2021) 138 (Supplement 1): 2293.

https://doi.org/10.1182/blood-2021-149851

Published: 2021

Journal Articles

Impact of Allogeneic Hematopoietic Stem Cell Transplantation in First Complete Remission and Additional Cytogenetic Aberrations at Diagnosis on Prognosis in 1256 Pediatric Patients with KMT2A-Rearranged Acute Myeloid Leukemia: A Retrospective Study By the I-BFM-SG

Blood (2021) 138 (Supplement 1): 2360.

https://doi.org/10.1182/blood-2021-148041

Published: 2021

Journal Articles

Increased Survival Disparities Among Children and Adolescents & Young Adults with Acute Myeloid Leukemia: A Dutch Population-Based Study

Maya Schulpen, Bianca F. Goemans, Gertjan J.L. Kaspers, Marc H.G.P. Raaijmakers, Christian M. Zwaan, Henrike E. Karim-Kos

Blood (2021) 138 (Supplement 1): 845.

https://doi.org/10.1182/blood-2021-145277

Published: 2021

Journal Articles

Selective Targeting of Alternative Splicing Deregulation in Pediatric Acute Myeloid Stem and Progenitor Cells

Inge Van Der Werf, MSc, Phoebe Mondala, BS, Raymond Diep, BS, Larissa Balaian, PhD, Cayla Mason, BS, Jacqueline Cloos, PhD, Gertjan J.L. Kaspers, Prof. MD PhD, Jim La Clair, Peggy Wentworth, Leslie A Crews, PhD, Thomas Whisenant, PhD, Kathleen Fisch, PhD, Michael Burkart, PhD, Catriona Jamieson, MD PhD

Blood (2020) 136 (Supplement 1): 8.

https://doi.org/10.1182/blood-2020-136596

Published: 2020

Journal Articles

The Molecular Characteristics and Clinical Relevance of NUP98 -Other Translocations in Pediatric Acute Myeloid Leukemia

Eline J.M. Bertrums, Jenny L. Smith, MSc, MD, Rhonda E. Ries, MA, Todd A. Alonzo, PhD, Fabiana Ostronoff, MD, Gertjan J.L. Kaspers, Prof. MD PhD, Henrik Hasle, PhD, Christian M. Zwaan, Betsy A Hirsch, PhD, Susana C. Raimondi, PhD, Todd M. Cooper, DO, Richard Aplenc, MD PhD, Alan S. Gamis, MD MPH, Edward A. Kolb, MD, Bianca F. Goemans, MD PhD, Soheil Meshinchi, MDPhD

Blood (2020) 136 (Supplement 1): 36–37.

https://doi.org/10.1182/blood-2020-137537

Published: 2020

Journal Articles

Outcome of (Novel) Subgroups in 1257 Pediatric Patients with KMT2A-Rearranged Acute Myeloid Leukemia (AML) and the Significance of Minimal Residual Disease (MRD) Status: A Retrospective Study By the I-BFM-SG

Blood (2020) 136 (Supplement 1): 26–27.

https://doi.org/10.1182/blood-2020-136064

Published: 2020

Journal Articles

Cumulative Incidence of Blood Stream Infections during Acute Myeloid Leukemia Treatment in the Netherlands: A 15-Year Overview

Emily Risa Schwartz, Sc.B., A.B., Kim Klein, MD MSc, Valerie de Haas, MD PhD, Birgit Lissenberg-Witte, PhD, Lynn Ball, MD, Natasja Dors, MD, Marry M Van den Heuvel-Eibrink, Prof, MD PhD, Rutger Knops, MD, Wim Tissing, MD, Birgitta A. Versluys, MD PhD, Christian M. Zwaan, MD, Raphaele R.L. van Litsenburg, MD PhD, Gertjan J.L. Kaspers, MD PhD

Blood (2018) 132 (Supplement 1): 2685.

https://doi.org/10.1182/blood-2018-99-114364

Published: 2018

Journal Articles

Obesity Is Associated with Favorable Cytogenetic Abnormalities in Pediatric Acute Myeloid Leukemia

Ditte Juel Adolfsen Løhmann, MD, Jonas Abrahamsson, MD PhD, Shau-Yin Ha, MD PhD, Olafur G. Jonsson, MD PhD, Gertjan J.L. Kaspers, MD PhD, Minna M Koskenvuo, MD PhD, Birgitte Lausen, MD PhD, Barbara De Moerloose, MD PhD, Josefine Palle, MD PhD, Bernward Zeller, MD PhD, Henrik Hasle, MD PhD, Lillian Sung, MD PhD

Blood (2017) 130 (Supplement 1): 1302.

https://doi.org/10.1182/blood.V130.Suppl_1.1302.1302

Published: 2017

Journal Articles

Differences in Infection Prophylaxis between Pediatric AML Study Groups within the International BFM Study Group

Kim Klein, MD MSc, Henrik Hasle, MD PhD, Jonas Abrahamsson, MD PhD, Barbara De Moerloose, MD PhD, Gertjan J.L. Kaspers, MD PhD

Blood (2017) 130 (Supplement 1): 2104.

https://doi.org/10.1182/blood.V130.Suppl_1.2104.2104

Published: 2017

Journal Articles

Targeted Deep Sequencing of GATA1 more Sensitively Identifies Transient Myeloproliferative Disorder in Neonates with Down Syndrome

Bianca F Goemans, MD PhD, Sanne Noort, MD MSc, Marjolein Blink, MD PhD, Ko van Wouwe, MD PhD, Gertjan J.L. Kaspers, MD PhD, Valerie de Haas, MD PhD, Wouter J.W. Kollen, MD PhD, Vincent van der Velden, PhD, Tanja A. Gruber, MD PhD, Michel Zwaan, MD PhD

Blood (2017) 130 (Supplement 1): 2919.

https://doi.org/10.1182/blood.V130.Suppl_1.2919.2919

Published: 2017

Journal Articles

A Dynamic Epigenetic Landscape in Genetic and Immunophenotypic Stable Pediatric AML

Diana Hanekamp, MSc, Jennifer R. Scheick, Yaseswini Neelamraju, Edwin Sonneveld, PhD, Valerie de Haas, MD PhD, Gert J. Ossenkoppele, MD PhD, Gerrit J. Schuurhuis, PhD, Gertjan J.L. Kaspers, MD PhD, Francine E. Garrett-Bakelman, MDPhD, Jacqueline Cloos, PhD

Blood (2017) 130 (Supplement 1): 2686.

https://doi.org/10.1182/blood.V130.Suppl_1.2686.2686

Published: 2017

Journal Articles

Characteristics and Outcomes of Pediatric Patients with t(16;16)-AML: Results of a Case Series By the International BFM Study Group

Kim Klein, MD MSc, Valerie de Haas, MD PhD, Jonas Abrahamsson, MD PhD, Todd A Alonzo, PhD, Brenda Gibson, MD PhD, Christine J Harrison, PhD FRCPath, Henrik Hasle, MD PhD, Betsy A Hirsch, PhD, Guy Leverger, MD PhD, Franco Locatelli, MD PhD, Susana C. Raimondi, PhD, Jeffrey E Rubnitz, MD PhD, Dirk Reinhardt, MD PhD, Daisuke Tomizawa, MD PhD, Gertjan J.L. Kaspers, MD PhD

Blood (2017) 130 (Supplement 1): 2671.

https://doi.org/10.1182/blood.V130.Suppl_1.2671.2671

Published: 2017

NARROW

Measurable Residual Disease Monitoring during Treatment for Pediatric Acute Myeloid Leukemia in First Relapse Predicts Outcome

Comparison of the WHO and ICC Classifications of Cytogenetic Abnormalities in Childhood Acute Myeloid Leukemia

Early Peripheral Blood Blast Clearance As a Prognostic Marker for Early Treatment Response in Pediatric Acute Myeloid Leukemia

Management of Hyperleukocytosis in Pediatric Acute Myeloid Leukemia Using Immediate Chemotherapy without Leukapheresis, in Protocol NOPHO-DBH AML-2012

Chip-AML22 Master Protocol: An Open-Label Clinical Trial in Newly Diagnosed Pediatric De Novo Acute Myeloid Leukemia (AML) Patients Including a Linked Phase II Trial with Quizartinib in FLT3 -ITD/ NPM1 wt Patients - a Study By the NOPHO-DB-SHIP Consortium

A Randomized Comparison of Liposomal Daunorubicin/Daunorubicin Combined with Low-Dose Cytarabine and Etoposide or High-Dose Cytarabine and Fludarabine in Induction Treatment of Pediatric AML Using MRD-Based Risk Stratification in the NOPHO-DBH AML 2012 Protocol

Decreased Embryonic Splicing Repressor Expression Enhances Splicing Modulator Sensitivity in Pediatric Acute Myeloid Leukemia Stem Cells

High Immunoproteasome Expression As Indicator for Sensitivity to Bortezomib-Containing Chemotherapy in Newly Diagnosed, Standard and Intermediate Risk, T-Cell Acute Lymphoblastic Leukemia Patients from Children's Oncology Group Trial AALL1231

Non-Infectious Morbidity during Pediatric Acute Myeloid Leukemia Chemotherapy in the Netherlands: A 15-Year Overview

Impact of Allogeneic Hematopoietic Stem Cell Transplantation in First Complete Remission and Additional Cytogenetic Aberrations at Diagnosis on Prognosis in 1256 Pediatric Patients with KMT2A-Rearranged Acute Myeloid Leukemia: A Retrospective Study By the I-BFM-SG

Increased Survival Disparities Among Children and Adolescents & Young Adults with Acute Myeloid Leukemia: A Dutch Population-Based Study

Selective Targeting of Alternative Splicing Deregulation in Pediatric Acute Myeloid Stem and Progenitor Cells

The Molecular Characteristics and Clinical Relevance of NUP98 -Other Translocations in Pediatric Acute Myeloid Leukemia

Outcome of (Novel) Subgroups in 1257 Pediatric Patients with KMT2A-Rearranged Acute Myeloid Leukemia (AML) and the Significance of Minimal Residual Disease (MRD) Status: A Retrospective Study By the I-BFM-SG

Cumulative Incidence of Blood Stream Infections during Acute Myeloid Leukemia Treatment in the Netherlands: A 15-Year Overview

Obesity Is Associated with Favorable Cytogenetic Abnormalities in Pediatric Acute Myeloid Leukemia

Differences in Infection Prophylaxis between Pediatric AML Study Groups within the International BFM Study Group

Targeted Deep Sequencing of GATA1 more Sensitively Identifies Transient Myeloproliferative Disorder in Neonates with Down Syndrome

A Dynamic Epigenetic Landscape in Genetic and Immunophenotypic Stable Pediatric AML

Characteristics and Outcomes of Pediatric Patients with t(16;16)-AML: Results of a Case Series By the International BFM Study Group

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