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Thomas Whisenant
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Journal Articles

Identifying the Impact of ADAR1 Inhibition on LSC Niche Remodeling in 3D Nanobioreactors

Larissa Balaian, Jessica Pham, Anna Kulidjian, Edward D. Ball, Thomas Whisenant, Michael Burkart, Catriona Jamieson
Journal: Blood
Blood (2024) 144 (Supplement 1): 1385.
https://doi.org/10.1182/blood-2024-211696
Published: 2024
Journal Articles

Defining the Roles of Base Deaminase and Splicing Deregulation in Pediatric B-Cell Acute Lymphoblastic Leukemia Stem Cell Persistence

Mrinal Joshirao, Inge Van Der Werf, Jessica Pham, Antonio W Ruiz, Neha Katragadda, Emma E Klacking, Elsa Molina, Ludmil Alexandrov, Thomas Whisenant, Catriona Jamieson
Journal: Blood
Blood (2024) 144 (Supplement 1): 1363.
https://doi.org/10.1182/blood-2024-211999
Published: 2024
Journal Articles

A 3D Niche Nanobioreactor Supports Long-Term Tracking of Hematopoietic Stem and Progenitor Cell Cycle Kinetics, Self-Renewal and Cell Fate Determination

Jenna S Sneifer, Jessica Pham, Inge Van Der Werf, Larissa Balaian, Emma E Klacking, Neha Katragadda, Luisa Ladel, Anna Kulidjian, Patrick Chang, Thomas Whisenant, Catriona Jamieson
Journal: Blood
Blood (2024) 144 (Supplement 1): 4068.
https://doi.org/10.1182/blood-2024-212259
Published: 2024
Journal Articles

Space-Associated Stem and Hematopoietic Cell Aging in Astronauts on Short-Duration Missions

Jessica Pham, Larissa Balaian, Patrick Chang, Shuvro P Nandi, Jenna S Sneifer, Antonio W Ruiz, Emma E Klacking, Inge Van Der Werf, Karla Mack, Neha Katragadda, Claire Engstrom, Cristian Quintero, Jane Isquith, Pinar Mesci, Elsa Molina, Jana Stoudemire, Thomas Whisenant, Ludmil Alexandrov, Catriona Jamieson
Journal: Blood
Blood (2024) 144 (Supplement 1): 5628.
https://doi.org/10.1182/blood-2024-212357
Published: 2024
Journal Articles

Selective Reversal of ADAR1 Splicing Prevents Leukemia Stem Cell Maintenance In Vivo

Wenxue Ma, Catriona Jamieson, Jessica Pham, Emma E Klacking, Neha Katragadda, Antonio W Ruiz, Thomas P Frias, James J. La Clair, Sheldon Morris, Anna Kulidjian, Thomas Whisenant
Journal: Blood
Blood (2024) 144 (Supplement 1): 5789.
https://doi.org/10.1182/blood-2024-212092
Published: 2024
Journal Articles

A Longitudinal Study to Assess Hematopoietic Stem Cell and Immune Cell Health in Astronauts Pre-, during, and Post-Mission

Jessica Pham, Larissa Balaian, Emma E Klacking, Antonio W Ruiz, Jenna Sneifer, Thomas P Frias, Jane Isquith, Shuvro P Nandi, Thomas Whisenant, Elsa Molina, Jana Stoudemire, Pinar Mesci, Ludmil Alexandrov, Catriona Jamieson
Journal: Blood
Blood (2023) 142 (Supplement 1): 4056.
https://doi.org/10.1182/blood-2023-187749
Published: 2023
Journal Articles

Decreased Embryonic Splicing Repressor Expression Enhances Splicing Modulator Sensitivity in Pediatric Acute Myeloid Leukemia Stem Cells

Inge Van Der Werf, Kathleen Steel, Phoebe Mondala, Larissa Balaian, Jacqueline Cloos, Gertjan J.L. Kaspers, James La Clair, Peggy Wentworth, Kathleen Fisch, Leslie Crews, Thomas Whisenant, Michael Burkart, Mary Donohoe, Catriona Jamieson
Journal: Blood
Blood (2022) 140 (Supplement 1): 3354–3355.
https://doi.org/10.1182/blood-2022-171145
Published: 2022
Journal Articles

Deregulation of Splicing in Pediatric Acute Myeloid Stem and Progenitor Cells

Phoebe Mondala, Inge Van Der Werf, Larisa Balaian, Kathleen Steel, Luisa Ladel, Cayla Mason, Raymond Diep, Jacqueline Cloos, Gertjan Kaspers, Markus J van Roosmalen, Ruben Van Boxtel, Warren Chan, Adam Mark, Mary Donohoe, James La Clair, Peggy Wentworth, Kathleen Fisch, Leslie A Crews, Thomas Whisenant, Michael Burkart, Catriona Jamieson
Journal: Blood
Blood (2021) 138 (Supplement 1): 2227.
https://doi.org/10.1182/blood-2021-154120
Published: 2021
Journal Articles

Selective Targeting of Alternative Splicing Deregulation in Pediatric Acute Myeloid Stem and Progenitor Cells

Inge Van Der Werf, MSc, Phoebe Mondala, BS, Raymond Diep, BS, Larissa Balaian, PhD, Cayla Mason, BS, Jacqueline Cloos, PhD, Gertjan J.L. Kaspers, Prof. MD PhD, Jim La Clair, Peggy Wentworth, Leslie A Crews, PhD, Thomas Whisenant, PhD, Kathleen Fisch, PhD, Michael Burkart, PhD, Catriona Jamieson, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 8.
https://doi.org/10.1182/blood-2020-136596
Published: 2020
Journal Articles

Imetelstat Inhibits Telomerase and Prevents Propagation of ADAR1-Activated Myeloproliferative Neoplasm and Leukemia Stem Cells

Wenxue Ma, MD PhD, Larissa Balaian, PhD, Phoebe Mondala, BS, Yudou He, BS, Cayla Mason, BS, Jessica Pham, B.S., Jeremy Lee, BS, Raymond Diep, BS, Sanja Coso, PhD, Kathleen Fisch, PhD, Adam Mark, MS, Sheldon Morris, MD MPH, Qingfei Jiang, PhD, Thomas Whisenant, PhD, Aleksandra Rizo, MD PhD, Fei Huang, PhD, Mary Donohoe, PhD, Ludmil Alexandrov, PhD, Catriona Jamieson, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 18.
https://doi.org/10.1182/blood-2020-140771
Published: 2020
Journal Articles

Inflammatory Cytokine Responsive Enzymatic Mutagenesis Fuels Myeloproliferative Neoplasm Pre-Leukemia Stem Cell Evolution

Catriona Jamieson, MD PhD, Qingfei Jiang, PhD, Frida Holm, PhD, Jane Isquith, MS, Adam Mark, Cayla Mason, BS, Wenxue Ma, MD PhD, Raymond H Diep, Jessica Pham, B.S., Eduardo Reynoso Moreno, PhD, Chanond A Nasamran, Xu Guorong, Amanda Birmingham, Leslie A Crews, PhD, Ludmil Alexandrov, Gabriel Pineda, PhD, Thomas Whisenant, Kathleen M Fisch
Journal: Blood
Blood (2019) 134 (Supplement_1): 3780.
https://doi.org/10.1182/blood-2019-131510
Published: 2019