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Journal Articles

Acute myeloid leukemias with UBTF tandem duplications are sensitive to menin inhibitors

Blood (2024) 143 (7): 619–630.

https://doi.org/10.1182/blood.2023021359

Published: 2024

Includes: Supplemental data

Journal Articles

Population Pharmacokinetics of Inotuzumab Ozogamicin (InO) As Single Agent in Pediatric Relapsed/Refractory Acute Lymphoblastic Leukemia - Results from the ITCC-059 Phase IA and Phase II Trial

Blood (2022) 140 (Supplement 1): 8845–8847.

https://doi.org/10.1182/blood-2022-165954

Published: 2022

Journal Articles

Inotuzumab Ozogamicin (InO) Combined with UKALL-R3 Modified Chemotherapy in Pediatric Patients with B-Cell Precursor CD22+ Acute Lymphoblastic Leukemia (BCP-ALL) - Results from the ITCC-059 Phase 1B Trial

Blood (2022) 140 (Supplement 1): 8976–8978.

https://doi.org/10.1182/blood-2022-163056

Published: 2022

Journal Articles

Potential Impact of Treatment with Inotuzumab Ozogamicin on Chimeric Antigen Receptor T-Cell Therapy in Children with Relapsed or Refractory Acute Lymphoblastic Leukemia

Valeria Ceolin, Erica Brivio, Susan R. Rheingold, Allison Barz Leahy, Britta Julia Vormoor, Maureen M. O'Brien, Jeremy Rubinstein, Krzysztof Kalwak, Barbara De Moerloose, Elad Jacoby, Peter Bader, José L. Fuster, Franco Locatelli, Peter Hoogerbrugge, Friso Calkoen, Christian M. Zwaan

Blood (2021) 138 (Supplement 1): 3824.

https://doi.org/10.1182/blood-2021-146556

Published: 2021

Journal Articles

Increased Survival Disparities Among Children and Adolescents & Young Adults with Acute Myeloid Leukemia: A Dutch Population-Based Study

Maya Schulpen, Bianca F. Goemans, Gertjan J.L. Kaspers, Marc H.G.P. Raaijmakers, Christian M. Zwaan, Henrike E. Karim-Kos

Blood (2021) 138 (Supplement 1): 845.

https://doi.org/10.1182/blood-2021-145277

Published: 2021

Journal Articles

A Phase I/II Study of Bosutinib in Pediatric Patients with Resistant/Intolerant or Newly Diagnosed Philadelphia Chromosome-Positive Chronic Myeloid Leukemia, Study ITCC (Innovative Therapies for Children with Cancer European Consortium) 054 and COG (Children's Oncology Group Consortium) AAML1921: Results from the Phase I Trial in Resistant/Intolerant Patients

Blood (2021) 138 (Supplement 1): 2558.

https://doi.org/10.1182/blood-2021-145709

Published: 2021

Journal Articles

Outcome of (Novel) Subgroups in 1257 Pediatric Patients with KMT2A-Rearranged Acute Myeloid Leukemia (AML) and the Significance of Minimal Residual Disease (MRD) Status: A Retrospective Study By the I-BFM-SG

Blood (2020) 136 (Supplement 1): 26–27.

https://doi.org/10.1182/blood-2020-136064

Published: 2020

Journal Articles

In Vitro Drug Response Profiling in BCP- and T-ALL Primary Samples Adds a Robust Functional Layer Enabling Optimized Guidance of Individualized Therapy in Relapsed and Refractory Pediatric Acute Leukemia Patients

Blood (2020) 136 (Supplement 1): 15–16.

https://doi.org/10.1182/blood-2020-142314

Published: 2020

Journal Articles

The Molecular Characteristics and Clinical Relevance of NUP98 -Other Translocations in Pediatric Acute Myeloid Leukemia

Eline J.M. Bertrums, Jenny L. Smith, MSc, MD, Rhonda E. Ries, MA, Todd A. Alonzo, PhD, Fabiana Ostronoff, MD, Gertjan J.L. Kaspers, Prof. MD PhD, Henrik Hasle, PhD, Christian M. Zwaan, Betsy A Hirsch, PhD, Susana C. Raimondi, PhD, Todd M. Cooper, DO, Richard Aplenc, MD PhD, Alan S. Gamis, MD MPH, Edward A. Kolb, MD, Bianca F. Goemans, MD PhD, Soheil Meshinchi, MDPhD

Blood (2020) 136 (Supplement 1): 36–37.

https://doi.org/10.1182/blood-2020-137537

Published: 2020

Journal Articles

Cumulative Incidence of Blood Stream Infections during Acute Myeloid Leukemia Treatment in the Netherlands: A 15-Year Overview

Emily Risa Schwartz, Sc.B., A.B., Kim Klein, MD MSc, Valerie de Haas, MD PhD, Birgit Lissenberg-Witte, PhD, Lynn Ball, MD, Natasja Dors, MD, Marry M Van den Heuvel-Eibrink, Prof, MD PhD, Rutger Knops, MD, Wim Tissing, MD, Birgitta A. Versluys, MD PhD, Christian M. Zwaan, MD, Raphaele R.L. van Litsenburg, MD PhD, Gertjan J.L. Kaspers, MD PhD

Blood (2018) 132 (Supplement 1): 2685.

https://doi.org/10.1182/blood-2018-99-114364

Published: 2018

Journal Articles

The Mir-193 Family Antagonizes Stem Cell Pathways and Is a Potent Tumor Suppressor in Childhood and Adult Acute Myeloid Leukemia

Blood (2015) 126 (23): 1244.

https://doi.org/10.1182/blood.V126.23.1244.1244

Published: 2015

Journal Articles

Population Pharmacokinetics of Erwinia Asparaginase in Pediatric ALL Patients

Sebastiaan D.T. Sassen, PharmD, Ron A.A. Mathôt, PharmD, PhD, Rob Pieters, MD PhD, Valerie de Haas, MD PhD, Gertjan JL Kaspers, MD PhD, Cor van den Bos, MDPhD, Wim JE Tissing, MD PhD, Maroeska D.W.M. te Loo, MD PhD, Marc B Bierings, MDPhD, Wouter J.W. Kollen, MD PhD, Christian M. Zwaan, MD PhD, Inge M. van der Sluis, MD PhD

Blood (2015) 126 (23): 1281.

https://doi.org/10.1182/blood.V126.23.1281.1281

Published: 2015

Journal Articles

A Double Blind Randomised Clinical Trial to Prevent Serious Side Effects of Dexamethasone during Pediatric Acute Lymphoblastic Leukemia Treatment

Lidewij T Warris, MD, Marry M van den Heuvel-Eibrink, MD PhD, Femke K Aarsen, MSc PhD, Saskia MF Pluijm, Marc B Bierings, MDPhD, Cor van den Bos, MDPhD, Christian M. Zwaan, MD PhD, Wim JE Tissing, MD PhD, Margreet A Veening, MD, Rob Pieters, MD PhD, Erica LT van den Akker, MDPhD

Blood (2015) 126 (23): 2495.

https://doi.org/10.1182/blood.V126.23.2495.2495

Published: 2015

Journal Articles

Phase 1/2 Study in Pediatric Patients with Relapsed/Refractory B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) Receiving Blinatumomab Treatment

Blood (2014) 124 (21): 2292.

https://doi.org/10.1182/blood.V124.21.2292.2292

Published: 2014

Journal Articles

Clofarabine in Combination with High-Dose Cytarabine and Liposomal Daunorubicin in Pediatric AML: Results of a Phase 1B Combination Study By the ITCC Consortium

Christian M. Zwaan, MD PhD, Michael Dworzak, MD PhD, Thomas Klingebiel, MD, Claudia Rössig, MD, Guy Leverger, MD, Jan Stary, Evelina S. de Bont, MDPhD, Satianand Ramnarain, MSc, Yves Bertrand, MD, Benoit Brethon, MD, Brigitte Strahm, MD, Gertjan J. Kaspers, MD PhD, Dirk Reinhardt, MD PhD

Blood (2014) 124 (21): 989.

https://doi.org/10.1182/blood.V124.21.989.989

Published: 2014

Journal Articles

Initial Results from a Phase 2 Study of Blinatumomab in Pediatric Patients with Relapsed/Refractory B-Cell Precursor Acute Lymphoblastic Leukemia

Blood (2014) 124 (21): 3703.

https://doi.org/10.1182/blood.V124.21.3703.3703

Published: 2014

Journal Articles

Immunophenotyping Versus Morphological Evaluation Of Fresh and Stabilized Cerebrospinal Fluid As Diagnostic Tool For CNS Involvement In Childhood Acute Lymphoblastic Leukemia

Edwin Sonneveld, PhD, Christian M. Zwaan, MD, PhD, Alita J van der Sluijs-Gelling, Valerie de Haas, MD, PhD, Rob Pieters, Vincent H.J. van der Velden, PhD

Blood (2013) 122 (21): 4950.

https://doi.org/10.1182/blood.V122.21.4950.4950

Published: 2013

Journal Articles

Safety and Pharmacokinetics Of Clofarabine In Combination With High-Dose Cytarabine and Liposomal Daunorubicin In Pediatric AML: Results Of a Phase 1 Combination Study By The ITCC Consortium

Christian M. Zwaan, Michael Dworzak, Thomas Klingebiel, MD, Claudia Rossig, MD, Guy Leverger, MD, Jan Stary, Evelina S. De Bont, MD, PhD, Satianand Ramnarain, MSc, Yves Bertrand, MD, Essam A Ghazaly, MD, Dirk Reinhardt

Blood (2013) 122 (21): 2693.

https://doi.org/10.1182/blood.V122.21.2693.2693

Published: 2013

Journal Articles

A Phase 1/2 Study Of Blinatumomab In Pediatric Patients With Relapsed/Refractory B-Cell Precursor Acute Lymphoblastic Leukemia

Blood (2013) 122 (21): 70.

https://doi.org/10.1182/blood.V122.21.70.70

Published: 2013

Journal Articles

Molecular Aberrations in 107 Children with Myelodysplastic Syndrome (MDS).

Blood (2012) 120 (21): 2802.

https://doi.org/10.1182/blood.V120.21.2802.2802

Published: 2012

NARROW

Acute myeloid leukemias with UBTF tandem duplications are sensitive to menin inhibitors

Population Pharmacokinetics of Inotuzumab Ozogamicin (InO) As Single Agent in Pediatric Relapsed/Refractory Acute Lymphoblastic Leukemia - Results from the ITCC-059 Phase IA and Phase II Trial

Inotuzumab Ozogamicin (InO) Combined with UKALL-R3 Modified Chemotherapy in Pediatric Patients with B-Cell Precursor CD22+ Acute Lymphoblastic Leukemia (BCP-ALL) - Results from the ITCC-059 Phase 1B Trial

Potential Impact of Treatment with Inotuzumab Ozogamicin on Chimeric Antigen Receptor T-Cell Therapy in Children with Relapsed or Refractory Acute Lymphoblastic Leukemia

Increased Survival Disparities Among Children and Adolescents & Young Adults with Acute Myeloid Leukemia: A Dutch Population-Based Study

Outcome of (Novel) Subgroups in 1257 Pediatric Patients with KMT2A-Rearranged Acute Myeloid Leukemia (AML) and the Significance of Minimal Residual Disease (MRD) Status: A Retrospective Study By the I-BFM-SG

In Vitro Drug Response Profiling in BCP- and T-ALL Primary Samples Adds a Robust Functional Layer Enabling Optimized Guidance of Individualized Therapy in Relapsed and Refractory Pediatric Acute Leukemia Patients

The Molecular Characteristics and Clinical Relevance of NUP98 -Other Translocations in Pediatric Acute Myeloid Leukemia

Cumulative Incidence of Blood Stream Infections during Acute Myeloid Leukemia Treatment in the Netherlands: A 15-Year Overview

The Mir-193 Family Antagonizes Stem Cell Pathways and Is a Potent Tumor Suppressor in Childhood and Adult Acute Myeloid Leukemia

Population Pharmacokinetics of Erwinia Asparaginase in Pediatric ALL Patients

A Double Blind Randomised Clinical Trial to Prevent Serious Side Effects of Dexamethasone during Pediatric Acute Lymphoblastic Leukemia Treatment

Phase 1/2 Study in Pediatric Patients with Relapsed/Refractory B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) Receiving Blinatumomab Treatment

Clofarabine in Combination with High-Dose Cytarabine and Liposomal Daunorubicin in Pediatric AML: Results of a Phase 1B Combination Study By the ITCC Consortium

Initial Results from a Phase 2 Study of Blinatumomab in Pediatric Patients with Relapsed/Refractory B-Cell Precursor Acute Lymphoblastic Leukemia

Immunophenotyping Versus Morphological Evaluation Of Fresh and Stabilized Cerebrospinal Fluid As Diagnostic Tool For CNS Involvement In Childhood Acute Lymphoblastic Leukemia

Safety and Pharmacokinetics Of Clofarabine In Combination With High-Dose Cytarabine and Liposomal Daunorubicin In Pediatric AML: Results Of a Phase 1 Combination Study By The ITCC Consortium

A Phase 1/2 Study Of Blinatumomab In Pediatric Patients With Relapsed/Refractory B-Cell Precursor Acute Lymphoblastic Leukemia

Molecular Aberrations in 107 Children with Myelodysplastic Syndrome (MDS).

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American Society of Hematology

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ASH Publications

American Society of Hematology

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