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Sherif Abdelhamed
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Journal Articles

Acute myeloid leukemias with UBTF tandem duplications are sensitive to menin inhibitors

Juan M. Barajas, Milad Rasouli, Masayuki Umeda, Ryan Hiltenbrand, Sherif Abdelhamed, Rebecca Mohnani, Bright Arthur, Tamara Westover, Melvin E. Thomas, III, Minoo Ashtiani, Laura J. Janke, Beisi Xu, Ti-Cheng Chang, Wojciech Rosikiewicz, Emily Xiong, Chandra Rolle, Jonathan Low, Reethu Krishan, Guangchun Song, Michael P. Walsh, Jing Ma, Jeffrey E. Rubnitz, Ilaria Iacobucci, Taosheng Chen, Anja Krippner-Heidenreich, Christian M. Zwaan, Olaf Heidenreich, Jeffery M. Klco
Journal: Blood
Blood (2024) 143 (7): 619–630.
https://doi.org/10.1182/blood.2023021359
Published: 2024
Includes: Supplemental data
Journal Articles

Establishing Immunocompetent Leukemia Models to Investigate the Impact of CAR T Cells on the Immune Microenvironment and Bone Marrow Niche

Sarah E. Moore, Jaquelyn T. Zoine, Jeremy Chase Crawford, Deanna Langfitt, Juan M. Barajas, Sherif Abdelhamed, Ilaria Iacobucci, Dalia Haydar, Giedre Krenciute, Charles G. Mullighan, Jeffery M. Klco, Stephen Gottschalk, Paul G. Thomas, Mireya Paulina Velasquez
Journal: Blood
Blood (2022) 140 (Supplement 1): 7376–7377.
https://doi.org/10.1182/blood-2022-169800
Published: 2022
Journal Articles

Histone Acetyltransferases Are Critical Interacting Proteins in NUP98-Rearranged Acute Myeloid Leukemia

Nicole L. Michmerhuizen, Masayuki Umeda, Ilaria Iacobucci, Bright Arthur, Danika Di Giacomo, Ryan Hiltenbrand, Pablo Portola, Sherif Abdelhamed, Hongling Huang, Peipei Zhou, Lingyun Long, Hao Shi, Yu Sun, Evangelia K. Papachristou, Chandra Chilamakuri, Clive S. D'Santos, Hongbo Chi, Jeffery M. Klco, Charles G. Mullighan
Journal: Blood
Blood (2022) 140 (Supplement 1): 2970–2971.
https://doi.org/10.1182/blood-2022-164927
Published: 2022
Journal Articles

Comprehensive Genomic Landscape and Clonal Architecture in Pediatric Patients with Monosomy 7

Tamara Westover, Sherif Abdelhamed, Emily Xiong, Michael P Walsh, Jing Ma, Jasmine C. Wong, Astrid Behnert, Mignon L. Loh, Kevin M. Shannon, Jeffery M. Klco
Journal: Blood
Blood (2022) 140 (Supplement 1): 5837–5838.
https://doi.org/10.1182/blood-2022-166915
Published: 2022
Journal Articles

Human Models of NUP98 -Rearranged Leukemia Reveal Fusion-Specific Molecular Mechanisms

Masayuki Umeda, Nicole L. Michmerhuizen, Ryan Hiltenbrand, Juan M. Barajas, Bright Arthur, Sherif Abdelhamed, Jing Ma, Tamara Westover, Jonathan Miller, Charles G. Mullighan, Jeffery M. Klco
Journal: Blood
Blood (2022) 140 (Supplement 1): 5833–5834.
https://doi.org/10.1182/blood-2022-164686
Published: 2022
Journal Articles

UBTF -TD Expression Is Necessary and Sufficient for Myeloid Cell Expansion

Juan M. Barajas, Sherif Abdelhamed, Tamara Westover, Masayuki Umeda, Ryan Hiltenbrand, Bright Arthur, Reethu Krishnan, Michael P Walsh, Jing Ma, Jeffery M. Klco
Journal: Blood
Blood (2022) 140 (Supplement 1): 8733–8734.
https://doi.org/10.1182/blood-2022-159628
Published: 2022
Journal Articles

Integrated Genomic Analysis Identifies UBTF Tandem Duplications As a Subtype-Defining Lesion in Pediatric Acute Myeloid Leukemia

Masayuki Umeda, Jing Ma, Benjamin J. Huang, Kohei Hagiwara, Tamara Westover, Sherif Abdelhamed, Juan Martin Barajas, Melvin Edward Thomas, III, Michael P Walsh, Guangchun Song, Liqing Tian, Yanling Liu, Xiaolong Chen, Pandurang Kolekar, Quang Tran, Scott Foy, Jamie L. Maciaszek, Andrew B Kleist, Amanda R. Leonti, Bensheng Ju, John Easton, Huiyun Wu, Virginia Valentine, Marc Valentine, Yen-Chun Liu, Rhonda E. Ries, Jenny L. Smith, Evan Parganas, Ilaria Iacobucci, Ryan Hiltenbrand, Jonathan Miller, Jason Myers, Evadnie Rampersaud, Delaram Rahbarinia, Michael Rusch, Gang Wu, Hiroto Inaba, Yi-Cheng Wang, Todd A. Alonzo, James R. Downing, Charles G. Mullighan, Stanley B Pounds, M. Madan Babu, Jinghui Zhang, Jeffrey E. Rubnitz, Soheil Meshinchi, Xiaotu Ma, Jeffery M. Klco
Journal: Blood
Blood (2021) 138 (Supplement 2): LBA-4.
https://doi.org/10.1182/blood-2021-155134
Published: 2021
Journal Articles

Microrna-155 Trafficking Incites Compartmental Inflammation in the Leukemic Niche

Ding-Wen Chen, PhD, Seul Jung, BS, Jian-Meng Fan, BS, Siqi Linsey Zhang, Theresa N Menna, BS, Zhe Zhang, PhD, Sherif Abdelhamed, PhD, Peter Kurre, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 36.
https://doi.org/10.1182/blood-2020-137758
Published: 2020
Journal Articles

NUP98-KDM5A Fusion Induces Hematopoietic Cell Proliferation and Alters Myelo-Erythropoietic Differentiation

Jonathan Miller, MD PhD, Ryan Hiltenbrand, MS, Tamara Lamprecht, BS, Aman Seth, MS, Sherif Abdelhamed, PhD, Ilaria Iacobucci, PhD, Charles G. Mullighan, MBBS, MD, Jeffery M. Klco, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3775.
https://doi.org/10.1182/blood-2019-130768
Published: 2019
Journal Articles

Leukemic Stress Targets the mTOR Pathway to Suppress Residual HSC in the BM Microenvironment

John T Butler, MLS(ASCP), Sherif Abdelhamed, PhD, Lina Gao, PhD, Jeong Lim, PhD, Terzah M Horton, MD PhD, Peter Kurre, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3730.
https://doi.org/10.1182/blood-2019-125682
Published: 2019
Journal Articles

Niche Regulation of Residual Hematopoietic Stem Cell Protein Synthesis By Extracellular Vesicle (EV) Trafficking in the Acute Myeloid Leukemia (AML) Microenvironment

Sherif Abdelhamed, PhD, John T Butler, MLS(ASCP), Ben Doron, BS, Mu-Shui Dai, MDPhD, Peter Kurre, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2442.
https://doi.org/10.1182/blood.V130.Suppl_1.2442.2442
Published: 2017
Journal Articles

AML Differentially Alters Fate and Function of Mesenchymal Stem- and Osteolineage Cells in the Leukemic Niche

Ben Doron, BS, Sherif Abdelhamed, PhD, Ryan M Mulqueen, B.S., Julja Burchard, M.S., Andrew Adey, PhD, Peter Kurre, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1197.
https://doi.org/10.1182/blood.V130.Suppl_1.1197.1197
Published: 2017
Journal Articles

Residual HSPC in the Leukemia Microenvironment Are Reprogrammed Via Extracellular Vesicle Trafficking

Sherif Abdelhamed, PhD, Noah I Hornick, PhD, Peter Kurre, MD
Journal: Blood
Blood (2016) 128 (22): 888.
https://doi.org/10.1182/blood.V128.22.888.888
Published: 2016