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Laura J. Janke
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Journal Articles

Acute myeloid leukemias with UBTF tandem duplications are sensitive to menin inhibitors

Juan M. Barajas, Milad Rasouli, Masayuki Umeda, Ryan Hiltenbrand, Sherif Abdelhamed, Rebecca Mohnani, Bright Arthur, Tamara Westover, Melvin E. Thomas, III, Minoo Ashtiani, Laura J. Janke, Beisi Xu, Ti-Cheng Chang, Wojciech Rosikiewicz, Emily Xiong, Chandra Rolle, Jonathan Low, Reethu Krishan, Guangchun Song, Michael P. Walsh, Jing Ma, Jeffrey E. Rubnitz, Ilaria Iacobucci, Taosheng Chen, Anja Krippner-Heidenreich, Christian M. Zwaan, Olaf Heidenreich, Jeffery M. Klco
Journal: Blood
Blood (2024) 143 (7): 619–630.
https://doi.org/10.1182/blood.2023021359
Published: 2024
Includes: Supplemental data
Journal Articles

Modeling and targeting of erythroleukemia by hematopoietic genome editing

Ilaria Iacobucci, Chunxu Qu, Elena Varotto, Laura J. Janke, Xu Yang, Aman Seth, Anang Shelat, Jake D. Friske, Reiji Fukano, Jiyang Yu, Burgess B. Freeman, III, James A. Kennedy, Adam S. Sperling, Rena Zheng, Yingzhe Wang, Harini Jogiraju, Kirsten M. Dickerson, Debbie Payne-Turner, Sarah M. Morris, Emily S. Hollis, Nina Ghosn, Georgia E. Haggard, R. Coleman Lindsley, Benjamin L. Ebert, Charles G. Mullighan
Journal: Blood
Blood (2021) 137 (12): 1628–1640.
https://doi.org/10.1182/blood.2020009103
Published: 2021
Includes: Supplemental data
Journal Articles

Hypertension is a modifiable risk factor for osteonecrosis in acute lymphoblastic leukemia

Laura J. Janke, Sara L. Van Driest, Mary V. Portera, Ravi V. Atreya, Joshua C. Denny, Deqing Pei, Cheng Cheng, Sue C. Kaste, Hiroto Inaba, Sima Jeha, Ching-Hon Pui, Mary V. Relling, Seth E. Karol
Journal: Blood
Blood (2019) 134 (12): 983–986.
https://doi.org/10.1182/blood.2019000006
Published: 2019
Includes: Supplemental data
Journal Articles

ETV6-NTRK3 induces aggressive acute lymphoblastic leukemia highly sensitive to selective TRK inhibition

Kathryn G. Roberts, Laura J. Janke, Yaqi Zhao, Aman Seth, Jing Ma, David Finkelstein, Steve Smith, Kevin Ebata, Brian B. Tuch, Stephen P. Hunger, Charles G. Mullighan
Journal: Blood
Blood (2018) 132 (8): 861–865.
https://doi.org/10.1182/blood-2018-05-849554
Published: 2018
Includes: Supplemental data
Journal Articles

Preclinical evaluation of NUDT15 -guided thiopurine therapy and its effects on toxicity and antileukemic efficacy

Rina Nishii, Takaya Moriyama, Laura J. Janke, Wenjian Yang, Chase C. Suiter, Ting-Nien Lin, Lie Li, Kentaro Kihira, Hidemi Toyoda, Ute Hofmann, Matthias Schwab, Masatoshi Takagi, Tomohiro Morio, Atsushi Manabe, Shirley Kham, Nan Jiang, Karen R. Rabin, Motohiro Kato, Katsuyoshi Koh, Allen Eng-Juh Yeoh, Hiroki Hori, Jun J. Yang
Journal: Blood
Blood (2018) 131 (22): 2466–2474.
https://doi.org/10.1182/blood-2017-11-815506
Published: 2018
Includes: Supplemental data
Journal Articles

Genetic Modeling and Therapeutic Targeting of ETV6-NTRK3 with Loxo-101in Acute Lymphoblastic Leukemia

Kathryn G. Roberts, PhD, Olga Bridges, Laura J. Janke, PhD, Kevin Ebata, PhD, Brian B Tuch, PhD, Nisha Nanda, PhD, Charles Mullighan, MBBS, MSc, MD
Journal: Blood
Blood (2016) 128 (22): 278.
https://doi.org/10.1182/blood.V128.22.278.278
Published: 2016
Journal Articles

The Genomic Landscape of Childhood and Adult Acute Erythroid Leukemia

Ilaria Iacobucci, PhD, Ji Wen, PhD, Manja Meggendorfer, PhD, Catherine Carmichael, John K Choi, MD, Katherine Masih, Yongjin Li, PhD, Debbie Payne, Daisuke Tomizawa, MD, PhD, Nobutaka Kiyokawa, MD PhD, Laura J. Janke, PhD, Thomas B. Alexander, MD MPH, Stanley Pounds, PhD, Lei Shi, PhD, Marcus Valentine, PhD, Giuseppe Basso, Franco Locatelli, MD, Shirley Kham Kow Yin, MD, Allen Yeoh Eng Juh, MD, Ries E Rhonda, Elliot Stieglitz, MD, Andrew Wei, Ian D Lewis, MBBS, PhD FRACP, FRCPA, Richard D'Andrea, PhD, Benjamin T. Kile, Jinghui Zhang, PhD, Mignon L. Loh, MD, Soheil Meshinchi, MD PhD, Torsten Haferlach, MD, Charles Mullighan, MBBS, MSc, MD
Journal: Blood
Blood (2016) 128 (22): 39.
https://doi.org/10.1182/blood.V128.22.39.39
Published: 2016
Journal Articles

Crenolanib is active against models of drug-resistant FLT3-ITD−positive acute myeloid leukemia

Eric I. Zimmerman, David C. Turner, Jassada Buaboonnam, Shuiying Hu, Shelley Orwick, Michael S. Roberts, Laura J. Janke, Abhijit Ramachandran, Clinton F. Stewart, Hiroto Inaba, Sharyn D. Baker
Journal: Blood
Blood (2013) 122 (22): 3607–3615.
https://doi.org/10.1182/blood-2013-07-513044
Published: 2013
Includes: Supplemental data