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Chandra Rolle
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Journal Articles

UBTF tandem duplications generate a nuclear export signal motif that drives an XPO1 dependency in leukemia

Free
Juan Barajas, Aaron Phillips, Jina Wang, Melvin Thomas, Lisett Contreras, Masayuki Umeda, Ryan Hiltenbrand, Guangchun Song, Mike Walsh, Lauren Ezzell, Elizabeth Caldwell, Kelly Churion, Tamara Westover, Emily Xiong, Chandra Rolle, Jamila Moore, Josi Lott, Sandi Radko-Juettner, Amit Kumar, Wenjie Qi, Beisi Xu, Evangelia Papachristou, Clive D'Santos, Jing Ma, Burgess Freeman, Laura Janke, Richard Kriwacki, Jeffery Klco
Journal: Blood
Blood (2025) 146 (Supplement 1): 986.
https://doi.org/10.1182/blood-2025-986
Published: 2025
Journal Articles

Characterizing the In Vivo impact of inflammation on Samd9l hematopoietic phenotypes.

Free
Melvin Thomas, Emily Xiong, Tamara Westover, Mike Walsh, Jing Ma, Chandra Rolle, Yonghui Ni, Steven Burden, Laura Janke, Stanley Pounds, Jeffery Klco
Journal: Blood
Blood (2025) 146 (Supplement 1): 2055.
https://doi.org/10.1182/blood-2025-2055
Published: 2025
Journal Articles

Acute myeloid leukemias with UBTF tandem duplications are sensitive to menin inhibitors

Free
Juan M. Barajas, Milad Rasouli, Masayuki Umeda, Ryan Hiltenbrand, Sherif Abdelhamed, Rebecca Mohnani, Bright Arthur, Tamara Westover, Melvin E. Thomas, III, Minoo Ashtiani, Laura J. Janke, Beisi Xu, Ti-Cheng Chang, Wojciech Rosikiewicz, Emily Xiong, Chandra Rolle, Jonathan Low, Reethu Krishan, Guangchun Song, Michael P. Walsh, Jing Ma, Jeffrey E. Rubnitz, Ilaria Iacobucci, Taosheng Chen, Anja Krippner-Heidenreich, Christian M. Zwaan, Olaf Heidenreich, Jeffery M. Klco
Journal: Blood
Blood (2024) 143 (7): 619–630.
https://doi.org/10.1182/blood.2023021359
Published: 2024
Includes: Supplemental data
Journal Articles

A Murine Model Harboring Cooperating DNMT3A and SF3B1 Mutations Phenocopies SF3B1 Driven Myelodysplastic Syndrome

Free
Lashanale Wallace, Ana Leal-Cervantes, Amina Metidji, Jacquelyn Myers, Chandra Rolle, Heather Tillman, Esther A. Obeng
Journal: Blood
Blood (2022) 140 (Supplement 1): 5862–5863.
https://doi.org/10.1182/blood-2022-170535
Published: 2022