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Alwin D.R. Huitema
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Journal Articles

APAL2020K/ITCC-101: A Phase I Trial of the Menin Inhibitor Ziftomenib in Combination with Chemotherapy in Children with Relapsed/Refractory KMT2A- rearranged , NUP98- rearranged , or NPM1- mutant Acute Leukemias

Elisabeth Salzer, Janine Stutterheim, Branko Cuglievan, Blake E. Tomkinson, Mollie Leoni, Harm Van Tinteren, Alwin D.R. Huitema, Marieke Willemse, Gwen L Nichols, Francisco Bautista, Sarah K. Tasian, Todd M Cooper, Christian Zwaan
Journal: Blood
Blood (2024) 144 (Supplement 1): 4265.3.
https://doi.org/10.1182/blood-2024-204583
Published: 2024
Journal Articles

Brigatinib Monotherapy in Children with R/R ALK+ ALCL, IMT, or Other Solid Tumors: Updated Results from the Brigaped (ITCC-098) Phase 1 Dose-Escalation Study

Charlotte Rigaud, Kim P.J. Schellekens, Christine Damm-Welk, Veronique Minard-Colin, Samuel D. Abbou, Gertruud Bakker, Auke Beishuizen, Maaike Boonstra-Schelfhorst, Laurence Brugières, Michela Casanova, Pascal Chastagner, Rana Dandis, Stéphane Ducassou, Natasha K.A. van Eijkelenburg, Nathalie Garnier, Michael J. Hanley, Alwin D.R. Huitema, Samantha Lampron, Yousif H. Matloub, Nicole Scobie, Florin Vranceanu, Jen-Hao Wu, Wilhelm Woessmann, C. Michel Zwaan, Reineke A. Schoot
Journal: Blood
Blood (2024) 144 (Supplement 1): 3108.
https://doi.org/10.1182/blood-2024-200077
Published: 2024
Journal Articles

Standard Fludarabine Dosing Results in Overexposure in Young Children Undergoing Hematopoietic Cell Transplantation

Julia Möhlmann, Lisanne Ploeg, van der, Jurgen Langenhorst, Tim Bognar, Kim Elst, van der, Marc Bierings, Alwin D.R. Huitema, Aurelia Vries Schultink, de, Caroline Lindemans
Journal: Blood
Blood (2024) 144 (Supplement 1): 4876.
https://doi.org/10.1182/blood-2024-199015
Published: 2024
Journal Articles

Population Pharmacokinetics of Inotuzumab Ozogamicin (InO) As Single Agent in Pediatric Relapsed/Refractory Acute Lymphoblastic Leukemia - Results from the ITCC-059 Phase IA and Phase II Trial

Edoardo Pennesi, Erica Brivio, Kathleen B. Pelletier, Ying Chen, Alwin D.R. Huitema, Yilin Jiang, Anneke C.J. Ammerlaan, Barbara Sleight, Franco Locatelli, Inge M. Van Der Sluis, Claudia Rossig, Christiane Chen-Santel, Bella Bielorai, Arnaud Petit, Jan Stary, Lucie Sramkova, Cristina Díaz de Heredia Rubio, Susana Rives, Aengus O'Marcaigh, Carmelo Rizzari, Gernot Engstler, Karsten Nysom, Alba Rubio-San-Simón, Francisco J. Bautista Sirvent, Bénédicte Bruno, Yives Bertrand, Benoit Brethon, Fanny Rialland, Genevieve Plat, Uta Dirksen, May Garrett, Christian M. Zwaan
Journal: Blood
Blood (2022) 140 (Supplement 1): 8845–8847.
https://doi.org/10.1182/blood-2022-165954
Published: 2022