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Journal Articles

Blinatumomab Added to Chemotherapy Improves Disease-Free Survival in Newly Diagnosed NCI Standard Risk Pediatric B-Acute Lymphoblastic Leukemia: Results from the Randomized Children's Oncology Group Study AALL1731

Rachel E. Rau, Sumit Gupta, John A. Kairalla, Karen R Rabin, Anne Angiolillo, Cindy Wang, Andrew J. Carroll, Susan Conway, Meenakshi Devidas, Lia Gore, Ilan R. Kirsch, Holly R. Kubaney, Amanda M Li, Jennifer L. McNeer, Olga Militano, Yvonne Moyer, Maureen M. O'Brien, Maki Okada, Shalini C. Reshmi, Mary Shago, Elizabeth R. Wagner, Naomi J. Winick, Brent L. Wood, Faraz Zaman, Gerhard Zugmaier, Sue Zupanec, Stephen P. Hunger, David T. Teachey, Elizabeth A. Raetz, Mignon L. Loh
Journal: Blood
Blood (2024) 144 (Supplement 1): 1.
https://doi.org/10.1182/blood-2024-207450
Published: 2024
Journal Articles

Genomic Biomarkers of Poor Outcome in Patients with T-Cell Lymphoblastic Lymphoma

Haley Newman, Lahari Uppuluri, Rawan Shraim, Carl E Allen, Kara L. Davis, Meenakshi Devidas, Caroline Diorio, Kimberly P. Dunsmore, Amira Elhachimi, David Frank, Lia Gore, Thomas Gross, Robert J. Hayashi, Terzah M. Horton, Andrew Hughes, Stephen P. Hunger, John Kim, Yimei Li, Stephanie Si Lim, Mignon L. Loh, Charles G. Mullighan, Adam B. Olshen, Petri Pölönen, Rachel E. Rau, Gongping Shi, Kai Tan, Tiffaney Vincent, Stuart S. Winter, Birte Wistinghausen, Brent L. Wood, Jason Xu, Jun J. Yang, Rodney R. Miles, Michelle L. Hermiston, David T. Teachey
Journal: Blood
Blood (2024) 144 (Supplement 1): 313.
https://doi.org/10.1182/blood-2024-203827
Published: 2024
Journal Articles

Clinical Factors Associated with Prolonged Cytopenias after CD19 Chimeric Antigen Receptor T-Cell Therapy for Pediatric B-Cell Acute Lymphoblastic Leukemia

Regina M. Myers, Yimei Li, Adam Lamble, Emily M. Hsieh, Samuel John, Gregory Dolan, Hongyan Liu, Lee Chen, Jennifer Sheppard, Amanda M. DiNofia, Colleen Annesley, Stephan A. Grupp, Deepa Bhojwani, Rebecca A. Gardner, Lia Gore, Susan R Rheingold, Nirali N. Shah, Michael A. Pulsipher
Journal: Blood
Blood (2024) 144 (Supplement 1): 4827.
https://doi.org/10.1182/blood-2024-202027
Published: 2024
Journal Articles

A Global Study of Novel Agents in Paediatric and Adolescent Relapsed and Refractory B-Cell Non-Hodgkin Lymphoma (Glo-BNHL)

Emma Seaford, Shanna Maycock, Sarah Alexander, Auke Beishuizen, Birte Wistinghausen, Veronique Minard-Colin, Charlotte Rigaud, Charles A Phillips, James B. Ford, Pamela R. Kearns, Anna Lawson, Ellie Williams, Zahra Ahmed, Mahnoor Muzaffar, Rhianna Parsons, Lia Gore, Nicole Scobie, Victoria Buenger, Carl Allen, Karin Mellgren, Catherine M. Bollard, Anne Auperin, Lucinda Billingham, Gladstone Austin Amos Burke
Journal: Blood
Blood (2023) 142 (Supplement 1): 3097.
https://doi.org/10.1182/blood-2023-178658
Published: 2023
Journal Articles

Impact of Treatment with Inotuzumab Ozogamicin before or after Chimeric Antigen Receptor T-Cell Therapy in Children with Relapsed/Refractory Acute Lymphoblastic Leukemia

Susan R Rheingold, Lingyun Ji, Lia Gore, Xinxin Xu, Deepa Bhojwani, Nirali N. Shah, Elizabeth A. Raetz, Mignon L. Loh, Maureen M. O'Brien
Journal: Blood
Blood (2023) 142 (Supplement 1): 2876.
https://doi.org/10.1182/blood-2023-183103
Published: 2023
Journal Articles

A Potential Paradigm for the Robust and Systematic Prioritisation of Assets in Academic-Led, Multi-Industry Collaborative Trials in Rare Populations (Glo-BNHL)

Emma Seaford, Nicole Scobie, Lia Gore, Sarah Alexander, Auke Beishuizen, Birte Wistinghausen, Veronique Minard-Colin, Catherine M. Bollard, Karin Mellgren, Carl Allen, Anne Auperin, Victoria Buenger, Pamela R. Kearns, Anna Lawson, Ellie Williams, Shanna Maycock, Zahra Ahmed, Mahnoor Muzaffar, Rhianna Parsons, Lucinda Billingham, Gladstone Austin Amos Burke
Journal: Blood
Blood (2023) 142 (Supplement 1): 6247.
https://doi.org/10.1182/blood-2023-178724
Published: 2023
Journal Articles

Population Pharmacokinetics (PPK) and Exposure-Response to Support Body Surface Area (BSA)-Based Dosing of Brentuximab Vedotin in Pediatric Patients with Advanced-Stage Newly-Diagnosed Hodgkin Lymphoma (HL)

Xiaofei Zhou, Diane R Mould, Anna R K Franklin, Lia Gore, Xiang Bai, Neeraj Gupta
Journal: Blood
Blood (2022) 140 (Supplement 1): 3724–3725.
https://doi.org/10.1182/blood-2022-160105
Published: 2022
Journal Articles

Prognostic Importance of Cytogenetic Subgroups in Relapse Risk Stratification in Children and Young Adults with First Relapsed B-ALL: A Children's Oncology Group Study AALL1331

Teena Bhatla, Laura Hogan, Xinxin Xu, Lingyun Ji, Andrew J. Carroll, Nyla A. Heerema, Mary Shago, Lia Gore, James A. Whitlock, Stephen P. Hunger, Mignon L. Loh, Patrick A. Brown
Journal: Blood
Blood (2022) 140 (Supplement 1): 3476–3477.
https://doi.org/10.1182/blood-2022-166523
Published: 2022
Journal Articles

The Impact of Cumulative Anesthesia Exposure on Neurocognitive Outcomes in Children with High-Risk Precursor B Acute Lymphoblastic Leukemia: A Multicenter Children's Oncology Group Study

Sarah Alexander, Sumit Gupta, John Kairalla, Emily Hibbitts, Hannah Weisman, Doralina Anghelescu, Naomi J Winick, Kevin R. Krull, Wanda L Salzer, Michael J. Burke, Lia Gore, Meenakshi Devidas, Stephen P. Hunger, Mignon L. Loh, Kristina Hardy
Journal: Blood
Blood (2022) 140 (Supplement 1): 2179–2180.
https://doi.org/10.1182/blood-2022-166765
Published: 2022
Journal Articles

A Pilot Study of Azacitidine As Epigenetic Priming for Chemotherapy in Infants Less Than 1 Year of Age with KMT2A -Rearranged Acute Lymphoblastic Leukemia (ALL); Results from the Children's Oncology Group (COG) Trial AALL15P1

Erin Guest, John Kairalla, Meenakshi Devidas, Emily Hibbitts, Andrew J. Carroll, Nyla A. Heerema, Holly Kubaney, Amanda August, Melinda Pauly, Daniel Wechsler, Rodney R. Miles, Joel M. Reid, Cynthia Kihei, Lia Gore, Elizabeth A. Raetz, Stephen P. Hunger, Mignon L. Loh, Patrick A. Brown
Journal: Blood
Blood (2022) 140 (Supplement 1): 3256–3257.
https://doi.org/10.1182/blood-2022-167765
Published: 2022
Journal Articles

Phase 1b Study of Carfilzomib in Combination with Induction Chemotherapy in Children with Relapsed or Refractory Acute Lymphoblastic Leukemia (ALL)

Michael J. Burke, David S. Ziegler, Francisco Bautista, Andishe Attarbaschi, Lia Gore, Franco Locatelli, Maureen M. O'Brien, Melinda Pauly, Mihaela Obreja, Christopher L. Morris, Andre Baruchel
Journal: Blood
Blood (2021) 138 (Supplement 1): 1235.
https://doi.org/10.1182/blood-2021-147588
Published: 2021
Journal Articles

Phase 2 Study of Carfilzomib in Combination with Induction Chemotherapy in Children with Relapsed or Refractory (R/R) Acute Lymphoblastic Leukemia (ALL)

David S. Ziegler, Van Huynh, Michael J. Burke, Lia Gore, Franco Locatelli, Maureen M. O'Brien, Christopher Kim, Mihaela Obreja, Christopher L. Morris, André Baruchel
Journal: Blood
Blood (2021) 138 (Supplement 1): 4403.
https://doi.org/10.1182/blood-2021-153865
Published: 2021
Journal Articles

A Randomized Phase 3 Trial of Blinatumomab Vs. Chemotherapy As Post-Reinduction Therapy in Low Risk (LR) First Relapse of B-Acute Lymphoblastic Leukemia (B-ALL) in Children and Adolescents/Young Adults (AYAs): A Report from Children's Oncology Group Study AALL1331

Patrick A. Brown, Lingyun Ji, Xinxin Xu, Meenakshi Devidas, Laura Hogan, Teena Bhatla, Michael Borowitz, Elizabeth A. Raetz, Lia Gore, James A. Whitlock, Stephen P. Hunger, Mignon L. Loh
Journal: Blood
Blood (2021) 138 (Supplement 1): 363.
https://doi.org/10.1182/blood-2021-147946
Published: 2021
Journal Articles

KMT2A Rearrangements Are Associated with Lineage Switch Following CD19 Targeting CAR T-Cell Therapy

Adam J. Lamble, Regina M. Myers, Agne Taraseviciute, Samuel John, Bonnie Yates, Seth M. Steinberg, Jennifer Sheppard, Alexandra E. Kovach, Brent L. Wood, Michael Borowitz, Maryalice Stetler-Stevenson, Constance M. Yuan, Vinodh Pillai, Toni Foley, Perry Chung, Lee Chen, Daniel W. Lee, Colleen Annesley, Amanda M. DiNofia, Stephan A. Grupp, Michael R Verneris, Lia Gore, Theodore W. Laetsch, Deepa Bhojwani, Patrick A. Brown, Michael A. Pulsipher, Susan R. Rheingold, Rebecca A Gardner, Nirali N. Shah
Journal: Blood
Blood (2021) 138 (Supplement 1): 256.
https://doi.org/10.1182/blood-2021-153336
Published: 2021
Journal Articles

Eliminating disparities improves outcomes

Lia Gore, Amy K. Keating
Journal: Blood
Blood (2021) 137 (4): 439–441.
https://doi.org/10.1182/blood.2020008976
Published: 2021
Journal Articles

A Phase 1/2 Study to Evaluate the Safety and Efficacy of Ponatinib with Chemotherapy in Pediatric Patients with Philadelphia Chromosome-Positive (Ph+) Acute Lymphoblastic Leukemia (ALL)

Yousif Matloub, MD, Lia Gore, MD, Mignon L. Loh, MD, Chin-Hon Pui, MD, Michael J. Hanley, PharmD, PhD, Vickie Lu, PhD, E. Jane Leonard, MSc, Muriel Granier, Andrea Biondi, MD, Lewis B. Silverman, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 47.
https://doi.org/10.1182/blood-2020-134724
Published: 2020
Journal Articles

Cytogenetic Subgroups Drive Risk Stratification and Response to Chemotherapy and Blinatumomab in Children and Young Adults with Relapsed B-ALL: A Children's Oncology Group Study

Teena Bhatla, MD, Laura Hogan, MD, Xinxin Xu, MS, Lingyun Ji, Andrew J Carroll, PhD, Nyla A Heerema, PhD, Mary Shago, PhD, Lia Gore, MD, James A. Whitlock, MD, Stephen P Hunger, MD, Mignon L. Loh, MD, Patrick A. Brown, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 16–17.
https://doi.org/10.1182/blood-2020-136364
Published: 2020
Journal Articles

Safety of Palbociclib in Combination with Chemotherapy in Pediatric and Young Adult Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia and Lymphoma: A Children's Oncology Group Pilot Study

Elizabeth A. Raetz, MD, David T. Teachey, MD, Charles Minard, PhD, Xiaowei Liu, MS, Robin Norris, MD MS, MPH, Joel Reid, PhD, Thalia Beeles, MPh, Lia Gore, MD, Elizabeth Fox, MD, Mignon L. Loh, MD, Brenda J. Weigel, MDMSc, William L. Carroll, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 20–21.
https://doi.org/10.1182/blood-2020-141572
Published: 2020
Journal Articles

Pre-CAR Blinatumomab Is Associated with Increased Post-CD19 CAR Relapse and Decreased Event Free Survival

Agne Taraseviciute, MD, Seth M. Steinberg, PhD, Regina M. Myers, MD, Lia Gore, MD, Adam J. Lamble, MD, Patrick A. Brown, MD, Jennifer Sheppard, Bonnie Yates, NP, Perry Chung, MD, Lee Chen, Colleen Annesley, MD, Deepa Bhojwani, MD, Theodore W. Laetsch, MD, Rebecca A Gardner, MD, Susan R. Rheingold, MD, Michael A Pulsipher, MD, Nirali N. Shah, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 13–14.
https://doi.org/10.1182/blood-2020-139260
Published: 2020
Journal Articles

A Randomized Phase 3 Trial of Blinatumomab Vs. Chemotherapy As Post-Reinduction Therapy in High and Intermediate Risk (HR/IR) First Relapse of B-Acute Lymphoblastic Leukemia (B-ALL) in Children and Adolescents/Young Adults (AYAs) Demonstrates Superior Efficacy and Tolerability of Blinatumomab: A Report from Children's Oncology Group Study AALL1331

Patrick A. Brown, MD, Lingyun Ji, PhD, Xinxin Xu, MS, Meenakshi Devidas, PhD, Laura Hogan, MD, Michael J. Borowitz, MD PhD, Elizabeth A. Raetz, MD, Gerhard Zugmaier, Elad Sharon, MD MPH, Lia Gore, MD, James A. Whitlock, MD, Michael A. Pulsipher, MD, Stephen P. Hunger, MD, Mignon L. Loh, MD
Journal: Blood
Blood (2019) 134 (Supplement_2): LBA-1.
https://doi.org/10.1182/blood-2019-132435
Published: 2019