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Journal Articles

Outcomes in children and adolescents with down syndrome and B-lymphoblastic leukemia: A report from Children's oncology group study AALL1731

Free
Amanda Li, John Kairalla, Cindy Wang, Meenakshi Devidas, Olga Militano, Johann Hitzler, Anne Angiolillo, Michael Burke, Wanda Salzer, Stephen Hunger, Naomi Winick, David Teachey, Elizabeth Raetz, Mignon Loh, Sumit Gupta, Rachel Rau, Karen Rabin
Journal: Blood
Blood (2025) 146 (Supplement 1): 547.
https://doi.org/10.1182/blood-2025-547
Published: 2025
Journal Articles

Outcomes in children with NCI standard-risk b-acute lymphoblastic leukemia treated with intensified post-induction therapy: Results from Children's Oncology Group studies AALL0932 and AALL1131

Free
Ruth Wang'ondu, Anne Angiolillo, Meenakshi Devidas, Karen Rabin, Michael Borowitz, Brent Wood, Andrew Carroll, Nyla Heerema, Emily Hibbitts, Reuven Schore, William Carroll, Michael Burke, Wanda Salzer, Lia Gore, Naomi Winick, David Teachey, Elizabeth Raetz, Mignon Loh, Stephen Hunger, John Kairalla
Journal: Blood
Blood (2025) 146 (Supplement 1): 757.
https://doi.org/10.1182/blood-2025-757
Published: 2025
Journal Articles

Blinatumomab mitigates the impact of traditional adverse prognosticators among children with standard risk b-acute lymphoblastic leukemia: Updated results of the Children's oncology group (COG) Trial AALL1731

Free
Sumit Gupta, Rachel Rau, John Kairalla, Karen Rabin, Cindy Wang, Anne Angiolillo, Sarah Alexander, Andrew Carroll, Susan Conway, Lia Gore, Ilan Kirsch, Holly Kubaney, Amanda Li, Jennifer McNeer, Olga Militano, Tamara Miller, Yvonne Moyer, Maureen O'Brien, Maki Okada, Shalini Reshmi, Mary Shago, Elizabeth Wagner, Naomi Winick, Brent Wood, Tara Haworth-Wright, Faraz Zaman, Gerhard Zugmaier, Sue Zupanec, Meenakshi Devidas, Stephen Hunger, David Teachey, Mignon Loh, Elizabeth Raetz
Journal: Blood
Blood (2025) 146 (Supplement 1): 758.
https://doi.org/10.1182/blood-2025-758
Published: 2025
Journal Articles

Ivosidenib with or without hypomethylating agent in IDH1-mutated AML: Real-world evidence to inform frontline therapy

Free
Tarun Bhagnani, Pierantonio Russo, Ramaa Nathan, Mostafa Shokoohi, Assaf Vestin, Anne Angiolillo
Journal: Blood
Blood (2025) 146 (Supplement 1): 6963.
https://doi.org/10.1182/blood-2025-6963
Published: 2025
Journal Articles

Antimetabolite dose intensity and adverse outcomes in children with acute lymphoblastic leukemia: a COG-AALL03N1 report

Free
Aman Wadhwa, Yanjun Chen, Lindsey Hageman, Anne Angiolillo, David S. Dickens, Joseph P. Neglia, Yaddanapudi Ravindranath, Amanda Termuhlen, F. Lennie Wong, Wendy Landier, Smita Bhatia
Journal: Blood
Blood (2024) 144 (22): 2327–2335.
https://doi.org/10.1182/blood.2024024455
Published: 2024
Includes: Supplemental data
Journal Articles

Immunoglobulin Sequencing Biologically Distinguishes B-Lymphoblastic Lymphoma from Acute Lymphoblastic Leukemia and Reveals a Spectrum of Disease Dissemination across Clinical Stages

Free
Carol Fries Simpson, Lik Wee Lee, Hongyue Wang, Diana G. Adlowitz, Philip Rock, Brent L. Wood, Rachel E. Rau, Kara L. Davis, Anne Angiolillo, Meenakshi Devidas, David T. Teachey, Karen R Rabin, Birte Wistinghausen, Donald Barkauskas, Robert J. Hayashi, Richard Burack, Carl E Allen, Michelle L. Hermiston, Ilan R. Kirsch
Journal: Blood
Blood (2024) 144 (Supplement 1): 2838.
https://doi.org/10.1182/blood-2024-201634
Published: 2024
Journal Articles

Improved Hematologic Recovery with Ivosidenib in Patients with mIDH1 Relapsed or Refractory MDS: Results from a Phase 1 Substudy

Free
Gabrielle T. Prince, Praneeth Baratam, Guillermo Garcia-Manero, Anne Angiolillo, Tarun Bhagnani, Assaf Vestin, Amir T. Fathi
Journal: Blood
Blood (2024) 144 (Supplement 1): 3226.
https://doi.org/10.1182/blood-2024-209071
Published: 2024
Journal Articles

Blinatumomab Added to Chemotherapy Improves Disease-Free Survival in Newly Diagnosed NCI Standard Risk Pediatric B-Acute Lymphoblastic Leukemia: Results from the Randomized Children's Oncology Group Study AALL1731

Free
Rachel E. Rau, Sumit Gupta, John A. Kairalla, Karen R Rabin, Anne Angiolillo, Cindy Wang, Andrew J. Carroll, Susan Conway, Meenakshi Devidas, Lia Gore, Ilan R. Kirsch, Holly R. Kubaney, Amanda M Li, Jennifer L. McNeer, Olga Militano, Yvonne Moyer, Maureen M. O'Brien, Maki Okada, Shalini C. Reshmi, Mary Shago, Elizabeth R. Wagner, Naomi J. Winick, Brent L. Wood, Faraz Zaman, Gerhard Zugmaier, Sue Zupanec, Stephen P. Hunger, David T. Teachey, Elizabeth A. Raetz, Mignon L. Loh
Journal: Blood
Blood (2024) 144 (Supplement 1): 1.
https://doi.org/10.1182/blood-2024-207450
Published: 2024
Journal Articles

Prognostic Impact of t(1;19) in Pediatric B-Cell Acute Lymphoblastic Leukemia (B-ALL) Patients Treated on Contemporary Children's Oncology Group (COG) Protocols

Free
Ashley Pinchinat, John A. Kairalla, Meenakshi Devidas, Andrew J. Carroll, Mary Shago, Anne Angiolillo, Michael J. Burke, Wanda L. Salzer, Naomi J. Winick, Mignon L. Loh, David T. Teachey, Elizabeth A. Raetz, Karen R Rabin, Rachel E. Rau, Sumit Gupta
Journal: Blood
Blood (2024) 144 (Supplement 1): 315.
https://doi.org/10.1182/blood-2024-198507
Published: 2024
Journal Articles

Utility of a Second Interim Maintenance Phase to Improve Outcomes for Pediatric Acute Lymphoblastic Leukemia: A Report from the Children's Oncology Group

Free
Etan Orgel, Michael J. Burke, John A. Kairalla, Emily Hibbitts, Meenakshi Devidas, Michael J. Borowitz, Brent L. Wood, Nyla A. Heerema, Andrew J. Carroll, Kelly Maloney, Leonard A. Mattano, Anne Angiolillo, Eric C. Larsen, Wanda L. Salzer, David T. Teachey, Naomi J. Winick, William L. Carroll, Stephen P. Hunger, Elizabeth A. Raetz, Mignon L. Loh
Journal: Blood
Blood (2024) 144 (Supplement 1): 2813.
https://doi.org/10.1182/blood-2024-194872
Published: 2024
Journal Articles

Outcomes By Frailty in IC-Ineligible Newly Diagnosed AML - a Real-World Evidence Comparison By Treatment with Hypomethylating Agents + Ivosidenib or Venetoclax

Free
B. Douglas Smith, Curtis A. Lachowiez, Alexander J. Ambinder, Gary Binder, Anne Angiolillo, Ravi Potluri, Eros Papademetriou, Thomas W. LeBlanc
Journal: Blood
Blood (2024) 144 (Supplement 1): 2855.
https://doi.org/10.1182/blood-2024-210603
Published: 2024
Journal Articles

Additional Induction Intrathecal Cytarabine for Patients with CNS2 Disease at Diagnosis Is Not Beneficial for Patients with B-ALL Treated on Children's Oncology Group Protocols AALL0932 and AALL1131

Free
Cathy A. Lee-Miller, John A. Kairalla, Emily Hibbitts, Naomi J. Winick, Anne Angiolillo, Reuven J. Schore, Wanda L. Salzer, Michael J. Burke, Mignon L. Loh, Elizabeth A. Raetz, Stephen P. Hunger, Meenakshi Devidas, David T. Teachey, Sumit Gupta, Jennifer L. McNeer
Journal: Blood
Blood (2024) 144 (Supplement 1): 4195.
https://doi.org/10.1182/blood-2024-203456
Published: 2024
Journal Articles

Association between High Antimetabolite Dose Intensity during Maintenance, Toxicities and Relapse Risk in Children with Acute Lymphoblastic Leukemia (ALL): COG-AALL03N1 Report

Free
Aman Wadhwa, Yanjun Chen, Lindsey Hageman, Anne Angiolillo, David Dickens, Joseph Neglia, Yaddanapudi Ravindranath, Amanda Muench Termuhlen, F. Lennie Wong, Wendy Landier, Smita Bhatia
Journal: Blood
Blood (2023) 142 (Supplement 1): 521.
https://doi.org/10.1182/blood-2023-187197
Published: 2023
Journal Articles

A Comparison of Acute Myeloid Leukemia (AML) Regimens: Hypomethylating Agents Combined with Ivosidenib or Venetoclax in Newly Diagnosed Patients with IDH1 Mutations: A Real-World Evidence Study

Free
B. Douglas Smith, Curtis A Lachowiez, Alexander Joseph Ambinder, Gary Binder, Anne Angiolillo, Assaf Vestin, Robert Paglia, Ravi Potluri, Eros Papademetriou, Thomas W LeBlanc
Journal: Blood
Blood (2023) 142 (Supplement 1): 971.
https://doi.org/10.1182/blood-2023-173033
Published: 2023
Journal Articles

Poverty and relapse risk in children with acute lymphoblastic leukemia: a Children’s Oncology Group study AALL03N1 report

Free
Clinical Trials & Observations
Aman Wadhwa, Yanjun Chen, Lindsey Hageman, Anna Hoppmann, Anne Angiolillo, David S. Dickens, Joseph P. Neglia, Yaddanapudi Ravindranath, A. Kim Ritchey, Amanda Termuhlen, F. Lennie Wong, Wendy Landier, Smita Bhatia
Journal: Blood
Blood (2023) 142 (3): 221–229.
https://doi.org/10.1182/blood.2023019631
Published: 2023
Includes: Supplemental data
Journal Articles

Outcomes of Patients with Down Syndrome and CRLF2 -Overexpressing Acute Lymphoblastic Leukemia (ALL): A Report from the Children's Oncology Group (COG)

Free
Karen R Rabin, MDPhD, Meenakshi Devidas, PhD, Zhiguo Chen, Yunfeng Dai, PhD, Sarah K Tasian, MD, Johann K Hitzler, MD, Kathryn G Roberts, PhD, Andrew J Carroll, PhD, Nyla A Heerema, PhD, Michael J Borowitz, MD PhD, Brent L Wood, MD PhD, Charles G Mullighan, MBBS, MD, Richard C Harvey, PhD, I-Ming L Chen, Cheryl L Willman, MD, Shalini C Reshmi, PhD, Julie M Gastier-Foster, PhD, Kelly W Maloney, MD, Eric C Larsen, MD, Reuven J Schore, MD, Michael J Burke, MD, Wanda L Salzer, MD, Naomi J Winick, MD, William L. Carroll, MD, Elizabeth A. Raetz, MD, Anne Angiolillo, MD, Mignon L. Loh, MD, Stephen P Hunger, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 44–45.
https://doi.org/10.1182/blood-2020-143165
Published: 2020
Journal Articles

Excellent Outcomes with Reduced Frequency of Vincristine and Dexamethasone Pulses in Children with National Cancer Institute (NCI) Standard-Risk B Acute Lymphoblastic Leukemia (SR B-ALL): A Report from Children's Oncology Group (COG) Study AALL0932

Free
Anne Angiolillo, MD, Reuven J. Schore, MD, John Kairalla, Meenakshi Devidas, Karen R. Rabin, MD PhD, Patrick A. Zweidler-McKay, MD PhD, Michael J. Borowitz, MD PhD, Brent L Wood, MD PhD, Andrew J. Carroll, PhD, Nyla A. Heerema, PhD, Mary V. Relling, PharmD, Ashley Lane, Kelly Maloney, MD, Cindy Wang, MS, William L. Carroll, MD, Naomi Winick, MD, Elizabeth A. Raetz, MD, Mignon L. Loh, MD, Stephen P. Hunger, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 824.
https://doi.org/10.1182/blood-2019-123565
Published: 2019
Journal Articles

The Genomic Landscape of Childhood Acute Lymphoblastic Leukemia

Free
Kathryn G. Roberts, PhD, Samuel W. Brady, PhD, Zhaohui Gu, PhD, Lei Shi, PhD, Stanley Pounds, PhD, Deqing Pei, MS, Cheng Cheng, PhD, Yunfeng Dai, PhD, Meenakshi Devidas, PhD, Chunxu Qu, PhD, Ashley Hill, BS, Xiaotu Ma, Lei Wei, PhD, Sasi Arunachalam, PhD, Kohei Hagiwara, MD, Yangling Liu, Diane Flasch, Yu Liu, PhD, Matthew Parker, PhD, Xiaolong Chen, PhD, Yongjin Li, PhD, Yiping Fan, PhD, Robert Michael, PhD, Michael Rusch, BS, Mark Wilkinson, Scott Foy, PhD, Dale Hedges, PhD, Scott Newman, PhD, Xin Zhou, PhD, Jian Wang, Shalini C. Reshmi, PhD, Julie M. Gastier-Foster, PhD, Patee Gesuwan, Malcolm A Smith, MD PhD, Daniela S. Gerhard, PhD, Naomi Winick, MD, Andrew J. Carroll, PhD, Nyla A. Heerema, PhD, Richard C. Harvey, PhD, Cheryl L. Willman, MD, Eric Larsen, MD, Elizabeth A. Raetz, MD, Michael J. Borowitz, MD PhD, Brent L Wood, MD PhD, William L. Carroll, MD, Patrick A. Zweidler-McKay, MD PhD, Karen R. Rabin, MD PhD, Leonard A. Mattano, MD, Kelly Maloney, MD, Stuart S. Winter, MD, Michael J. Burke, MD, Wanda L. Salzer, MD, Kimberly P. Dunsmore, Anne Angiolillo, MD, Kristine R Crews, PharmD, James R. Downing, MD, Sima Jeha, MD, William E. Evans, PharmD, Ching-Hon Pui, MD, Jun J. Yang, PhD, Mary V. Relling, PharmD, Stephen P. Hunger, MD, Mignon L. Loh, MD, Jinghui Zhang, PhD, Charles G. Mullighan, MBBS, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 649.
https://doi.org/10.1182/blood-2019-124881
Published: 2019
Journal Articles

Genomic and Outcome Analyses of Philadelphia Chromosome-like (Ph-like) NCI Standard Risk B-Acute Lymphoblastic Leukemia (SR B-ALL) Patients Treated on Children's Oncology Group (COG) AALL0331

Free
Shalini C. Reshmi, PhD, Richard C. Harvey, PhD, Kathryn G. Roberts, PhD, Eileen Stonerock, BS, ASCP(MB), Yunfeng Dai, PhD, I-Ming L. Chen, DVM, MS, Marc Valentine, BA, Yu Liu, PhD, Yongjin Li, PhD, Jinghui Zhang, PhD, Debbie Payne-Turner, BS, Meenakshi Devidas, PhD, Nyla A. Heerema, PhD, Andrew Carroll, PhD, Elizabeth A. Raetz, MD, Michael Borowitz, MD PhD, Brent Wood, MDPhD, Anne Angiolillo, MD, Michael J. Burke, MD, Wanda Salzer, MD, Patrick A. Zweidler-McKay, MDPhD, Karen R. Rabin, MD PhD, Leonard A. Mattano, MD, Kelly Maloney, MD, William L. Carroll, MD, Mignon L. Loh, MD, Charles G. Mullighan, MBBS, MD, Cheryl L. Willman, MD, Julie M. Gastier-Foster, PhD, Stephen P. Hunger, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 477.
https://doi.org/10.1182/blood.V130.Suppl_1.477.477
Published: 2017
Journal Articles

Intensification of Oral Methotrexate Is Not Superior to Standard Methotrexate Dosing during Maintenance in Children with National Cancer Institute (NCI) Standard-Risk B Acute Lymphoblastic Leukemia (SR B-ALL): A Report from Children's Oncology Group (COG) Study AALL0932

Free
Anne Angiolillo, MD, Reuven Schore, MD, Meenakshi Devidas, Xiaomin Lu, PhD, Karen R. Rabin, MD PhD, Patrick A. Zweidler-McKay, MDPhD, Michael Borowitz, MD PhD, Brent Wood, MDPhD, Andrew J. Carroll, III, PhD, Nyla A. Heerema, PhD, Cindy Wang, MS, Kelly Maloney, MD, Naomi Winick, MD, William L. Carroll, MD, Elizabeth A. Raetz, MD, Mignon L. Loh, MD, Stephen P. Hunger, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 140.
https://doi.org/10.1182/blood.V130.Suppl_1.140.140
Published: 2017