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Journal Articles

Selective SMARCA2 Degradation Promotes Leukemic Differentiation and Synergizes with CDK9 Inhibition to Potently Induce Death in Pre-Clinical Models of Acute Myeloid Leukemia

Norman Fultang, Ashley M Schwab, Ian Johnson, Alexander Grego, Emma Filler, Carly Bachner, Jake Karwoski, Andrew Moore, Ashley Bartilomo, Anjana Agarwal, Olusola Peace Osinubi, Koichi Ito, Sarah Aminov, Srabani Sahu, Amit Verma, Peggy A Scherle, Neha Bhagwat, Diane Heiser
Journal: Blood
Blood (2024) 144 (Supplement 1): 2774.
https://doi.org/10.1182/blood-2024-208196
Published: 2024
Journal Articles

Favourable Outcomes in Newly Diagnosed Paediatric AML with Gemtuzumab Ozogamicin and Risk-Stratified Therapy: Results from the International Phase III Myechild 01 Trial

Brenda Gibson, Andre Baruchel, Andrew Moore, Shanna Maycock, Owen Smith, Geoff Shenton, Jean-Pierre Bourquin, Yves Bertrand, Nicholas Heaney, Anna Lawson, Persis Jal Amrolia, Gerard Michel, Jean-Hugues Dalle, Marc Ansari, Hélène Lapillonne, Richard Dillon, Jelena Jovanovic, Siobhan Cross, Paul Virgo, Lucy Wheeler, Christophe Roumier, Nicolas Duployez, Christine Harrison, Claire Schwab, Wendy Cuccuini, Marina Lafage-Pochitaloff, Claude Preudhomme, Paresh Vyas, Pierre Hirsch, Gareth Veal, David Gillis, Pam Kearns, Guy Leverger, Phil Ancliff, Aimee Jackson, Arnaud Petit
Journal: Blood
Blood (2024) 144 (Supplement 1): 968.
https://doi.org/10.1182/blood-2024-198419
Published: 2024
Journal Articles

Outcomes for Children with High Risk Acute Myeloid Leukemia on the Myechild 01 International Phase III Clinical Trial

Andrew Moore, Shanna Maycock, Guy Leverger, Owen Smith, Andre Baruchel, Yves Bertrand, Phil Ancliff, Nicholas Heaney, Geoff Shenton, Arnaud Petit, Jean-Pierre Bourquin, Aimee Jackson, Anna Lawson, Persis Amrolia, Gerard Michel, Jean-Hugues Dalle, Marc Ansari, Hélène Lapillonne, Richard Dillon, Jelena Jovanovic, Christophe Roumier, Nicolas Duployez, Christine Harrison, Claire Schwab, Wendy Cuccuini, Marina Lafage-Pochitaloff, Paresh Vyas, Pierre Hirsch, Gareth Veal, Pam Kearns, Brenda Gibson
Journal: Blood
Blood (2023) 142 (Supplement 1): 730.
https://doi.org/10.1182/blood-2023-181593
Published: 2023
Journal Articles

STAG2/LMO2 Gamma-Delta (γδ) T-ALL: Identification and Characterization of an Extremely High Risk Group of T-ALL in the Very Young

Shunsuke Kimura, Petri Pölönen, Lindsey Montefiori, Kenneth Caldwell, Ilaria Iacobucci, Chelsey Chen, Anthony Brown, Katie Han, Yen-Chun Liu, Yunchao Chang, Zhongshan Cheng, Zhou Yinmei, Chun Shik Park, Sharnise Mitchell, Noemi Reyes, Allen Yeoh, Andishe Attarbaschi, Andrew Moore, Atsushi Manabe, Barbara Buldini, Kean Hui Chiew, Chi Kong Li, Ching-Hon Pui, Chunxu Qu, Daisuke Tomizawa, Elisabeth Paietta, Franco Locatelli, Gabriele Escherich, Gao Qingsong, Hannah Elisa Muhle, Hanne Vibeke Marquart, Hester A. de Groot-Kruseman, Jacob M. Rowe, Jan Stary, Jan Trka, John Kim Choi, Jules P.P. Meijerink, Junko Takita, Katarzyna Pawinska-Wasikowska, Kjeld Schmiegelow, Mariko Eguchi, Martin Schrappe, Martin Zimmermann, Masatoshi Takagi, Melissa Maybury, Michael Svaton, Michaela Reiterova, Michal Kicinski, Motohiro Kato, Orietta Spinelli, Pauline Mazilier, Paul G. Thomas, Riccardo Masetti, Rishi Sury Kotecha, Rob Pieters, Sarah Elitzur, Selina M Luger, Shuhong Shen, Sima Jeha, Steven M. Kornblau, Szymon Skoczen, Takako Miyamura, Tiffaney Vincent, Toshihiko Imamura, Valentino Conter, Yanjing Tang, Zhaohui Gu, Kathryn G. Roberts, David T. Teachey, Kristine R Crews, Cheng Cheng, Jun J. Yang, Hiroto Inaba, Charles G. Mullighan
Journal: Blood
Blood (2023) 142 (Supplement 1): 845.
https://doi.org/10.1182/blood-2023-178688
Published: 2023
Journal Articles

A Phase 1 Dose Escalation Study of Protein Arginine Methyltransferase 5 (PRMT5) Inhibitor PRT543 in Patients with Myeloid Malignancies

Manish R. Patel, Varun Monga, Shekeab Jauhari, Don Stevens, Lucia Masarova, Meredith McKean, David Mauro, John Viscusi, Peggy Scherle, Neha Bhagwat, Andrew Moore, William Sun, Rachel Chiaverelli, Eric Mintah, Rajneesh Nath, Eytan M. Stein, Neil Palmisiano, Grerk Sutamtewagul, Srdan Verstovsek
Journal: Blood
Blood (2021) 138 (Supplement 1): 2609.
https://doi.org/10.1182/blood-2021-150938
Published: 2021
Journal Articles

ZAP-70 constitutively regulates gene expression and protein synthesis in chronic lymphocytic leukemia

Jingyu Chen, Vijitha Sathiaseelan, Andrew Moore, Shengjiang Tan, Chandra Sekkar Reddy Chilamakuri, Valar Nila Roamio Franklin, Arash Shahsavari, Constanze A. Jakwerth, Sandra B. Hake, Alan J. Warren, Irina Mohorianu, Clive D’Santos, Ingo Ringshausen
Journal: Blood
Blood (2021) 137 (26): 3629–3640.
https://doi.org/10.1182/blood.2020009960
Published: 2021
Includes: Supplemental data
Journal Articles

Overcoming Multidrug Resistance in B Cell Malignancies By Antagonism of Stromal Mediated TGF-β Signalling

Eugene Park, PhD, Jingyu Chen, PhD, Andrew Moore, PhD, Michael Leitges, Seth E. Frietze, PhD, Ingo Ringshausen, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 17.
https://doi.org/10.1182/blood-2020-141952
Published: 2020
Journal Articles

Outcome of Children Relapsing after First Allogeneic Hematopoietic Stem Cell Transplantation for Pediatric Acute Myeloid Leukemia: A Retrospective I-BFM Analysis of 336 Children between 2005 and 2016

Theodor Uden, Alice Bertaina, MD PhD, Jonas Abrahamsson, MD PhD, Marc Ansari, MD, Adriana Balduzzi, MD, Jean-Pierre Bourquin, MD PhD, Corinne Gerhardt, Mark Bierings, MD, Henrik Hasle, MD, Arjan Lankester, MD PhD, Kirsten Mischke, Andrew Moore, MD, Ian Nivison-Smith, PhD, Anna Pieczonka, MD, Christina Peters, MD, Petr Sedlacek, MD, Dirk Reinhardt, MD, Jerry Stein, MD, Brigitta Versluys, MD, Jacek Wachowiak, Prof MDPhD, Leen Wiilems, MD, Martin Zimmermann, PhD, Franco Locatelli, MD PhD, Martin G. Sauer
Journal: Blood
Blood (2017) 130 (Supplement 1): 272.
https://doi.org/10.1182/blood.V130.Suppl_1.272.272
Published: 2017
Journal Articles

Integration of innate into adaptive immune responses in ZAP-70–positive chronic lymphocytic leukemia

Michaela Wagner, Madlen Oelsner, Andrew Moore, Frederik Götte, Peer-Hendrik Kuhn, Torsten Haferlach, Michael Fiegl, Christian Bogner, E. Joanna Baxter, Christian Peschel, George A. Follows, Ingo Ringshausen
Journal: Blood
Blood (2016) 127 (4): 436–448.
https://doi.org/10.1182/blood-2015-05-646935
Published: 2016
Includes: Supplemental data