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Alexander Grego
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Journal Articles

Selective SMARCA2 Degradation Promotes Leukemic Differentiation and Synergizes with CDK9 Inhibition to Potently Induce Death in Pre-Clinical Models of Acute Myeloid Leukemia

Norman Fultang, Ashley M Schwab, Ian Johnson, Alexander Grego, Emma Filler, Carly Bachner, Jake Karwoski, Andrew Moore, Ashley Bartilomo, Anjana Agarwal, Olusola Peace Osinubi, Koichi Ito, Sarah Aminov, Srabani Sahu, Amit Verma, Peggy A Scherle, Neha Bhagwat, Diane Heiser
Journal: Blood
Blood (2024) 144 (Supplement 1): 2774.
https://doi.org/10.1182/blood-2024-208196
Published: 2024
Journal Articles

PRMT5 Inhibition Modulates E2F1 Methylation and Gene Regulatory Networks Leading to Therapeutic Efficacy in JAK2VF Mutant MPN

Friederike Pastore, MD, Neha Bhagwat, PhDBS, Aishwarya Krishnan, Alessandro Pastore, Bing Li, MD, Robert L Bowman, PhD, Wenbin Xiao, MD PhD, Aaron D Viny, MDMS, Abdul Karzai, Anouar Zouak, Young C Park, Keith Cordner, Stephanie Braunstein, Alexander Grego, Jaanvi Mehta, Benjamin H Durham, MD, Richard P. Koche, PhD, Jesper Maag, Peggy Scherle, PhD, Kris Vaddi, PhD, Ross L. Levine, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 473.
https://doi.org/10.1182/blood-2019-127122
Published: 2019