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Christine Harrison
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Journal Articles

Favourable Outcomes in Newly Diagnosed Paediatric AML with Gemtuzumab Ozogamicin and Risk-Stratified Therapy: Results from the International Phase III Myechild 01 Trial

Brenda Gibson, Andre Baruchel, Andrew Moore, Shanna Maycock, Owen Smith, Geoff Shenton, Jean-Pierre Bourquin, Yves Bertrand, Nicholas Heaney, Anna Lawson, Persis Jal Amrolia, Gerard Michel, Jean-Hugues Dalle, Marc Ansari, Hélène Lapillonne, Richard Dillon, Jelena Jovanovic, Siobhan Cross, Paul Virgo, Lucy Wheeler, Christophe Roumier, Nicolas Duployez, Christine Harrison, Claire Schwab, Wendy Cuccuini, Marina Lafage-Pochitaloff, Claude Preudhomme, Paresh Vyas, Pierre Hirsch, Gareth Veal, David Gillis, Pam Kearns, Guy Leverger, Phil Ancliff, Aimee Jackson, Arnaud Petit
Journal: Blood
Blood (2024) 144 (Supplement 1): 968.
https://doi.org/10.1182/blood-2024-198419
Published: 2024
Journal Articles

Outcomes for Children with High Risk Acute Myeloid Leukemia on the Myechild 01 International Phase III Clinical Trial

Andrew Moore, Shanna Maycock, Guy Leverger, Owen Smith, Andre Baruchel, Yves Bertrand, Phil Ancliff, Nicholas Heaney, Geoff Shenton, Arnaud Petit, Jean-Pierre Bourquin, Aimee Jackson, Anna Lawson, Persis Amrolia, Gerard Michel, Jean-Hugues Dalle, Marc Ansari, Hélène Lapillonne, Richard Dillon, Jelena Jovanovic, Christophe Roumier, Nicolas Duployez, Christine Harrison, Claire Schwab, Wendy Cuccuini, Marina Lafage-Pochitaloff, Paresh Vyas, Pierre Hirsch, Gareth Veal, Pam Kearns, Brenda Gibson
Journal: Blood
Blood (2023) 142 (Supplement 1): 730.
https://doi.org/10.1182/blood-2023-181593
Published: 2023
Journal Articles

Improved Diagnosis of Intrachromosomal Amplification of Chromosome 21 (iAMP21) By Copy Number Profiling

Claire Schwab, Paul Sinclair, PhD, Anthony V. Moorman, PhD, Stephen Hunger, MD, Mignon L. Loh, MD, Andrew J. Carroll, PhD, Nyla A. Heerema, PhD, Christine Harrison
Journal: Blood
Blood (2016) 128 (22): 1733.
https://doi.org/10.1182/blood.V128.22.1733.1733
Published: 2016
Journal Articles

Integrating Genetic Risk Factors with Age, Presenting White Cell Count and MRD Response As Continuous Variables to Predict Relapse in Paediatric Acute Lymphoblastic Leukemia (ALL)

Anthony V. Moorman, PhD, Amir Enshaei, PhD, David O'Connor, MD PhD, Jack Bartram, MD, Jeremy Hancock, PhD, Christine Harrison, Sujith Samarasinghe, MD PhD, John Moppett, MD PhD, Ajay J. Vora, Nicholas Goulden, MD PhD
Journal: Blood
Blood (2016) 128 (22): 603.
https://doi.org/10.1182/blood.V128.22.603.603
Published: 2016
Journal Articles

A Novel Multiplex NGS-Based Digital MLPA Assay for Copy Number Detection of 700 Target Sequences in Childhood Acute Lymphoblastic Leukemia

Anne Benard, Ilse Zondervan, Jan Schouten, Karel de Groot, Farzaneh Ghazavi, Virinder Sarhadi, Pieter Van Vlierberghe, PhD, Barbara De Moerloose, MD, Christine Harrison, Claire Schwab, Sakari Knuutila, Tim Lammens, Suvi Savola
Journal: Blood
Blood (2016) 128 (22): 4071.
https://doi.org/10.1182/blood.V128.22.4071.4071
Published: 2016
Journal Articles

The Frequency and Outcome of Ph-like ALL Associated Abnormalities in Childhood Acute Lymphoblastic Leukaemia Treated on MRC UKALL2003

Claire Schwab, Amir Enshaei, PhD, Kathryn G. Roberts, PhD, Lisa J. Russell, PhD, Richard C Harvey, PhD, I-Ming L. Chen, DVM, MS, Cheryl L. Willman, Charles Mullighan, MBBS, MSc, MD, Ajay J. Vora, Anthony V. Moorman, PhD, Christine Harrison
Journal: Blood
Blood (2016) 128 (22): 2914.
https://doi.org/10.1182/blood.V128.22.2914.2914
Published: 2016
Journal Articles

The Prognostic Impact of Cytogenetics and Karyotype Changes in Pediatric Patients with Relapsed Acute Myeloid Leukemia: A Retrospective Cohort Study within the Relapsed AML 2001/01 Study

Kim Klein, MD, Martin Zimmermann, PhD, Berna Beverloo, PhD, Christine von Neuhoff, MD, Valerie De Haas, MD PhD, Romy van Weelderen, BSc, Susana C. Raimondi, PhD, Jacqueline Cloos, PhD, Jonas Abrahamsson, Yves Bertrand, MD PhD, Michael Dworzak, MD, Sarah Elitzur, MD, Alcira Fynn, MD, Brenda Gibson, MD PhD, Shau Yin Ha, MBBS, Christine Harrison, Henrik Hasle, MD, Guy Leverger, MD, Alexey Maschan, MD PhD, Bassem I. Razzouk, MD PhD, Dirk Reinhardt, MD PhD, Carmelo Rizzari, MD, Petr Smisek, MD, Ursula Creutzig, MD PhD, Gertjan J.L. Kaspers, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2896.
https://doi.org/10.1182/blood.V128.22.2896.2896
Published: 2016
Journal Articles

Fluorescence in Situ Hybridisation (FISH) Detection of Prognostically Relevant Chromosomal Abnormalities in Childhood Acute Myeloid Leukaemia (AML)

Claire Schwab, Deniz Bakkalci, BSc, Brenda Gibson, MD PhD, Christine Harrison
Journal: Blood
Blood (2016) 128 (22): 2897.
https://doi.org/10.1182/blood.V128.22.2897.2897
Published: 2016
Journal Articles

Long Term Overall Survival of Greater Than 98% in Childhood ALL Patients with Good Risk Features and Low Risk MRD:Â Results from a Large Multi-Center Randomized Controlled Trial, UKALL 2003

Jack Bartram, MD, David O'Connor, MD PhD, Amir Enshaei, PhD, Anthony V Moorman, PhD, Christine Harrison, PhDFRCPath FMedSci, Rachel Wade, MSc, Rachel Clack, MSc, Jeremy Hancock, PhD, Sujith Samarasinghe, MD PhD, John Moppett, MD PhD, Ajay J. Vora, Nicholas Goulden, MD PhD
Journal: Blood
Blood (2015) 126 (23): 806.
https://doi.org/10.1182/blood.V126.23.806.806
Published: 2015
Journal Articles

Risk Factor Analysis in Paediatric Acute Lymphoblastic Leukaemia with High Hyperdiploidy

Amir Enshaei, PhD, Claire Schwab, Lucy Chilton, PhD, Rachel Wade, MSc, Jeremy Hancock, PhD, Christopher Mitchell, MBBS, PhD FRCP, Sally E Kinsey, Nicholas Goulden, MD PhD, Ajay J. Vora, Christine Harrison, PhDFRCPath FMedSci, Anthony V. Moorman, PhD
Journal: Blood
Blood (2015) 126 (23): 805.
https://doi.org/10.1182/blood.V126.23.805.805
Published: 2015
Journal Articles

Integration of Minimal Residual Disease with Other Patient Risk Factors Identifies a Population with Very Poor Overall Survival in Pediatric ALL: Results from the UKALL 2003 Trial

David O'Connor, MD PhD, Jack Bartram, MD, Amir Enshaei, PhD, Anthony V Moorman, PhD, Christine Harrison, PhDFRCPath FMedSci, Rachel Wade, MSc, Rachel Clack, MSc, Jeremy Hancock, PhD, Sujith Samarasinghe, MD PhD, John Moppett, MD PhD, Ajay J. Vora, Nicholas Goulden, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1412.
https://doi.org/10.1182/blood.V126.23.1412.1412
Published: 2015
Journal Articles

Prognostic Significance and Risk Stratification in Acute Myeloid Leukaemia Patients in the Absence of Successful Cytogenetic Analysis

Lucy Chilton, PhD, Christine Harrison, PhDFRCPath FMedSci, Anthony V. Moorman, PhD, Iona Ashworth, Alan K. Burnett, MD FRCP, David Grimwade, PhD FRCPath, Robert K Hills, MA MSc DPhil
Journal: Blood
Blood (2015) 126 (23): 1379.
https://doi.org/10.1182/blood.V126.23.1379.1379
Published: 2015
Journal Articles

Clincial and Genetic Landscapes Differ Between IGH-CRLF2 and P2RY8-CRLF2 Acute Lymphoblastic Leukaemia

Lisa Jane Russell, PhD, Lisa Jones, BSc, Amir Enshaei, PhD, Jamie Rutherford, BSc, Stefano Tonin, PhD, Sarra Ryan, PhD, Jeyanthy Eswaran, PhD, Elli Papaemmanuil, PhD, Jose Tubio, PhD, Peter J Campbell, MD PhD, Anthony V Moorman, PhD, Christine Harrison, PhDFRCPath FMedSci
Journal: Blood
Blood (2015) 126 (23): 1426.
https://doi.org/10.1182/blood.V126.23.1426.1426
Published: 2015
Journal Articles

A Targeted Functional Clone Tracking Assay for the Identification of Tumour Suppressor Genes in BCP- ALL Implicates the Transcription Factors FOXO3 and PRDM1

Paul Sinclair, PhD, Joanna Cheng, Prahlad Raninga, Rebecca Hanna, Shaun Hollern, Amir Enshaei, PhD, Helen Blair, PhD, Sirintra Nakjang, Sarra Ryan, PhD, Jeyanthy Eswaran, PhD, Lars Buechler, Olaf Heidenreich, PhD, Christine Harrison, PhDFRCPath FMedSci
Journal: Blood
Blood (2015) 126 (23): 2449.
https://doi.org/10.1182/blood.V126.23.2449.2449
Published: 2015
Journal Articles

Genetic Characterisation of Immunoglobulin Heavy Chain Locus CCAAT Enhancer-Binding Protein Translocated Acute Lymphoblastic Leukaemia

Dino Mašić, MRes, Amir Enshaei, PhD, Lisa Jones, BSc, Christine Harrison, PhDFRCPath FMedSci, Lisa Jane Russell, PhD
Journal: Blood
Blood (2015) 126 (23): 2624.
https://doi.org/10.1182/blood.V126.23.2624.2624
Published: 2015
Journal Articles

Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition

Julie Irving, Elizabeth Matheson, Lynne Minto, Helen Blair, Marian Case, Christina Halsey, Isabella Swidenbank, Frida Ponthan, Renate Kirschner-Schwabe, Stefanie Groeneveld-Krentz, Jana Hof, James Allan, Christine Harrison, Josef Vormoor, Arend von Stackelberg, Cornelia Eckert
Journal: Blood
Blood (2014) 124 (23): 3420–3430.
https://doi.org/10.1182/blood-2014-04-531871
Published: 2014
Includes: Supplemental data
Journal Articles

DOWN'S Syndrome Acute Lymphoblastic LEUKEMIA: A HIGHLY Heterogeneous DISEASE DRIVEN by an Aberrant CRLF2/JAK2 Cooperation – A REPORT FROM the Ibfm-STUDY GROUP.

Libi Hertzberg, MSc, Elena Vendramini, Ithamar Ganmore, BSc, Giovanni Cazzaniga, Maike Schmitz, MSc, Ruth Shiloh, BSc, Jane Chalker, Ilaria Iacobucci, Chen Shochat, Sharon Zeligson, Gunnar Cario, Martin Stanulla, MD, Sabine Strehl, PhD, Lisa J Russel, PhD, Christine Harrison, Beat Bornhauser, PhD, Akinori Yoda, Ph.D., Gideon Rechavi, MD, PhD, Dani Bercovich, PhD, Arndt Borkardt, Helena Kempski, Geertruy te Kronnie, PhD, Jean-Pierre Bourquin, MD, PhD, Eytan Domany, PhD, Shai Izraeli, MD
Journal: Blood
Blood (2009) 114 (22): 11.
https://doi.org/10.1182/blood.V114.22.11.11
Published: 2009
Journal Articles

Assessment of Aneuploidy in Childhood Acute Lymphoblastic Leukaemia Using High Density Oligonucleotide Arrays.

Andrew G. Hall, PhD, Sarina Sulong, Christine Harrison, PhD, Lynne Minto, Nick Bown, PhD, Marian C. Case, Simon Bailey, PhD, Julie Irving, PhD
Journal: Blood
Blood (2006) 108 (11): 104.
https://doi.org/10.1182/blood.V108.11.104.104
Published: 2006
Journal Articles

Mutation in Genes Impacting on the RAS-RAF-MEK-ERK Pathway Are Found at High Incidence in Childhood Acute Lymphoblastic Leukemia at Both Diagnosis and at Relapse.

Julie Irving, Lynne Minto, Elizabeth Matheson, Marian Case, Simon Bailey, Nick Bown, Rosline Hassan, Christine Harrison, Andrew Hall
Journal: Blood
Blood (2006) 108 (11): 4328.
https://doi.org/10.1182/blood.V108.11.4328.4328
Published: 2006
Journal Articles

Comprehensive Analysis of p16 INK4a in Childhood Acute Lymphoblastic Leukemia Reveals Homozygous Deletion, Haploinsufficiency and Acquired Isodisomy at the 9p Locus with Intact p16 INK4a .

Sarina Sulong, Julie Irving, Marian Case, Lynne Minto, Nick Bown, Simon Bailey, Christine Harrison, Andrew Hall
Journal: Blood
Blood (2006) 108 (11): 4332.
https://doi.org/10.1182/blood.V108.11.4332.4332
Published: 2006