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Marian Case
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Journal Articles

Label-Free Analyses of Minimal Residual Disease in ALL Using Deep Learning and Imaging Flow Cytometry

Minh Doan, Marian Case, Dino Mašić, PhD, Holger Hennig, Claire McQuin, Allen Goodman, Juan Caicedo, Olaf Wolkenhauer, Huw Summers, Anne E Carpenter, Andy Filby, Paul Rees, Julie Irving, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1437.
https://doi.org/10.1182/blood.V130.Suppl_1.1437.1437
Published: 2017
Journal Articles

Exploring Pre-B Cell Receptor Signalling As a Therapeutic Target in Acute Lymphoblastic Leukaemia

Ali Alhammer, M.Sc, Marian Case, MSc, Helen J Blair, PhD, Josef Vormoor, MD FRCPCH, Julie Irving, PhD
Journal: Blood
Blood (2016) 128 (22): 4066.
https://doi.org/10.1182/blood.V128.22.4066.4066
Published: 2016
Journal Articles

Validation of MRD Quantification By Flow Cytometry for Pediatric BCP ALL Relapsed Patients Treated on the Intreall Protocol

Ester Mejstrikova, MD PhD, Julie Irving, Leonid Karawajew, Marian Case, Jenny Jesson, Vaskar Saha, PhD FRCP, FRCPath, Nicholas Goulden, MD PhD, Jeremy Hancock, PhD, Arend Stackelberg, MD, Sarah Lawson, Michael Dworzak, MD, Renate Panzer-Grumayer, Barbara Buldini, Lisa Eyre, Giuseppe Basso, MD, Maddalena Paganin, Jan Trka, Daniela Kužílková, Jan Stary, Lucie Sramkova, MD, Ondrej Hrusak, MD PhD, Cornelia Eckert
Journal: Blood
Blood (2015) 126 (23): 1414.
https://doi.org/10.1182/blood.V126.23.1414.1414
Published: 2015
Journal Articles

Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition

Julie Irving, Elizabeth Matheson, Lynne Minto, Helen Blair, Marian Case, Christina Halsey, Isabella Swidenbank, Frida Ponthan, Renate Kirschner-Schwabe, Stefanie Groeneveld-Krentz, Jana Hof, James Allan, Christine Harrison, Josef Vormoor, Arend von Stackelberg, Cornelia Eckert
Journal: Blood
Blood (2014) 124 (23): 3420–3430.
https://doi.org/10.1182/blood-2014-04-531871
Published: 2014
Includes: Supplemental data
Journal Articles

RAS Pathway Mutations Are Highly Prevalent In Relapsed Childhood Acute Lymphoblastic Leukaemia, Are Frequently Relapse-Drivers and Confer Sensitivity To MEK Inhibition

Julie Irving, PhD, Elizabeth C. Matheson, MPhil, Lynne Minto, Helen Blair, PhD, Marian Case, MSc, Christina Halsey, MD, PhD, Isabella Swidenbank, MRes, Frida Ponthan, PhD, Renate Kirschner-Schwabe, PhD, Stefanie Groeneveld-Krentz, MSc, Jana Hof, MSc, James Allan, PhD, Christine J. Harrison, PhD, Josef Vormoor, MD, Arend Stackelberg, MD, Cornelia Eckert, PhD
Journal: Blood
Blood (2013) 122 (21): 823.
https://doi.org/10.1182/blood.V122.21.823.823
Published: 2013
Journal Articles

In Childhood ALL, Both Blasts with a CD20 −/Low and a CD20 High Immunophenotype Have the Ability to Transfer the Leukemia Onto Immune-Deficient NOD/Scid Y −/− Mice.

Kerrie Wilson, BSc(Hons), Klaus Rehe, MD, Simon Bomken, MD, Marian Case, MSc, Leonard Shultz, PhD, Julie Irving, PhD, Josef Vormoor, MD, FRCPCH
Journal: Blood
Blood (2008) 112 (11): 1348.
https://doi.org/10.1182/blood.V112.11.1348.1348
Published: 2008
Journal Articles

The CD34 + CD38 Low CD19 + Candidate Leukemic Stem Cell Phenotype Revisited: Useful for Flow MRD Monitoring?

Kerrie Wilson, BSc(Hons), Marian Case, MSc, Lynne Minto, Simon Bailey, MD, PhD, FRCPCH, Josef Vormoor, MD, FRCPCH, Julie Irving, PhD
Journal: Blood
Blood (2008) 112 (11): 2505.
https://doi.org/10.1182/blood.V112.11.2505.2505
Published: 2008
Journal Articles

Mutation in Genes Impacting on the RAS-RAF-MEK-ERK Pathway Are Found at High Incidence in Childhood Acute Lymphoblastic Leukemia at Both Diagnosis and at Relapse.

Julie Irving, Lynne Minto, Elizabeth Matheson, Marian Case, Simon Bailey, Nick Bown, Rosline Hassan, Christine Harrison, Andrew Hall
Journal: Blood
Blood (2006) 108 (11): 4328.
https://doi.org/10.1182/blood.V108.11.4328.4328
Published: 2006
Journal Articles

Comprehensive Analysis of p16 INK4a in Childhood Acute Lymphoblastic Leukemia Reveals Homozygous Deletion, Haploinsufficiency and Acquired Isodisomy at the 9p Locus with Intact p16 INK4a .

Sarina Sulong, Julie Irving, Marian Case, Lynne Minto, Nick Bown, Simon Bailey, Christine Harrison, Andrew Hall
Journal: Blood
Blood (2006) 108 (11): 4332.
https://doi.org/10.1182/blood.V108.11.4332.4332
Published: 2006