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Journal Articles

The p53-MDM2 Antagonist RG7388 Activates p53 and Induces a Predominantly Pro-Apoptotic Gene Expression Signature in Chronic Lymphocytic Leukemia

Carmela Ciardullo, PhD, Laura Woodhouse, PhD, Erhan Aptullahoglu, MSc, Jonathan P Wallis, MD, Helen J Marr, MD PhD, Scott R Marshall, MD, Nick Bown, PhD, Elaine Willmore, PhD, John Lunec, PhD
Journal: Blood
Blood (2016) 128 (22): 893.
https://doi.org/10.1182/blood.V128.22.893.893
Published: 2016
Journal Articles

The Role of HOXA4 in Chronic Lymphocytic Leukaemia Progression and Response to Therapy

Timothy M Barrow, PhD, Laura Woodhouse, PhD, Gesa Junge, PhD, Susan J Tudhope, PhD, Charlotte Behardien, BSc, Jonathan P Wallis, MD, Helen J Marr, MD PhD, Scott R Marshall, MD, Nick Bown, PhD, Elaine Willmore, BSc, PhD, Gordon Strathdee, BSc, PhD
Journal: Blood
Blood (2016) 128 (22): 3924.
https://doi.org/10.1182/blood.V128.22.3924.3924
Published: 2016
Journal Articles

A United Kingdom Population-Based Study of Survival in Patients Aged 19 to 60 with Acute Myeloid Leukaemia in the Era of Molecular Genetics

McGregor K Andrew, BSc (Hons) MB ChB (Hons), MRCP (UK), PGCert ClinEd, FHEA, Deborah Moulton, FRCPath,MBBS,MRCP, Nick Bown, Gavin Cuthbert, Sue Matthew, Philip Mounter, Raymond Kai Bong Dang, MD FRCP, FRCPath, MBBS,, Gail Jones, MD
Journal: Blood
Blood (2014) 124 (21): 5275.
https://doi.org/10.1182/blood.V124.21.5275.5275
Published: 2014
Journal Articles

The Genomic Landscape Of Lineage Switch Acute Leukemia

Olaf Heidenreich, PhD, Ricky Tirtakusuma, MRes, Simon Bomken, PhD, MBBS, Dan Williamson, Sarah E Fordham, PhD, Hesta McNeill, Claus Meyer, PhD, Rolf Marschalek, PhD, Josef Vormoor, MD, Andrew Hall, Julie Irving, PhD, Helen J Blair, PhD, Dan Swan, Bronia Baker, Peter Carey, Nick Bown, David Bourn, Paul Evans, Roderick Skinner, PhD, MBChB, FRCPCH, Simon Bailey, Vikki Rand, PhD, James Allan, PhD
Journal: Blood
Blood (2013) 122 (21): 2552.
https://doi.org/10.1182/blood.V122.21.2552.2552
Published: 2013
Journal Articles

Response: Age- and sex-adjusted incidence rates of adults with acute lymphoblastic leukemia (ALL) in the northern part of England

Anthony V. Moorman, Lucy Chilton, Jennifer Wilkinson, Hannah M. Ensor, Nick Bown, Stephen J. Proctor
Journal: Blood
Blood (2010) 116 (6): 1012.
https://doi.org/10.1182/blood-2010-04-278895
Published: 2010
Journal Articles

A population-based cytogenetic study of adults with acute lymphoblastic leukemia

Clinical Trials & Observations
Anthony V. Moorman, Lucy Chilton, Jennifer Wilkinson, Hannah M. Ensor, Nick Bown, Stephen J. Proctor
Journal: Blood
Blood (2010) 115 (2): 206–214.
https://doi.org/10.1182/blood-2009-07-232124
Published: 2010
Journal Articles

Assessment of Aneuploidy in Childhood Acute Lymphoblastic Leukaemia Using High Density Oligonucleotide Arrays.

Andrew G. Hall, PhD, Sarina Sulong, Christine Harrison, PhD, Lynne Minto, Nick Bown, PhD, Marian C. Case, Simon Bailey, PhD, Julie Irving, PhD
Journal: Blood
Blood (2006) 108 (11): 104.
https://doi.org/10.1182/blood.V108.11.104.104
Published: 2006
Journal Articles

Mutation in Genes Impacting on the RAS-RAF-MEK-ERK Pathway Are Found at High Incidence in Childhood Acute Lymphoblastic Leukemia at Both Diagnosis and at Relapse.

Julie Irving, Lynne Minto, Elizabeth Matheson, Marian Case, Simon Bailey, Nick Bown, Rosline Hassan, Christine Harrison, Andrew Hall
Journal: Blood
Blood (2006) 108 (11): 4328.
https://doi.org/10.1182/blood.V108.11.4328.4328
Published: 2006
Journal Articles

Comprehensive Analysis of p16 INK4a in Childhood Acute Lymphoblastic Leukemia Reveals Homozygous Deletion, Haploinsufficiency and Acquired Isodisomy at the 9p Locus with Intact p16 INK4a .

Sarina Sulong, Julie Irving, Marian Case, Lynne Minto, Nick Bown, Simon Bailey, Christine Harrison, Andrew Hall
Journal: Blood
Blood (2006) 108 (11): 4332.
https://doi.org/10.1182/blood.V108.11.4332.4332
Published: 2006
Journal Articles

Imatinib improves but may not fully reverse the poor prognosis of patients with CML with derivative chromosome 9 deletions

Clinical Trials & Observations
Brian J. P. Huntly, Francois Guilhot, Alistair G. Reid, George Vassiliou, Evelin Hennig, Christina Franke, Jennie Byrne, Andre Brizard, Dietger Niederwieser, Julie Freeman-Edward, Gavin Cuthbert, Nick Bown, Richard E. Clark, Elizabeth P Nacheva, Anthony R Green, Michael W. N. Deininger
Journal: Blood
Blood (2003) 102 (6): 2205–2212.
https://doi.org/10.1182/blood-2002-09-2763
Published: 2003
Journal Articles

Transient response to imatinib mesylate (STI571) in a patient with the ETV6-ABL t(9;12) translocation

Clinical Trials & Observations Brief Report
Stephen G. O'Brien, Sara A. D. Vieira, Samantha Connors, Nick Bown, James Chang, Renaud Capdeville, Junia V. Melo
Journal: Blood
Blood (2002) 99 (9): 3465–3467.
https://doi.org/10.1182/blood.V99.9.3465
Published: 2002
Journal Articles

Deletions of the derivative chromosome 9 do not account for the poor prognosis associated with Philadelphia-positive acute lymphoblastic leukemia

Alistair G. Reid, Brian J. P. Huntly, Eveline Hennig, Dietger Niederwieser, Lynda J. Campbell, Nick Bown, Nick Telford, Helen Walker, Colin D. Grace, Michael W. Deininger, Anthony R. Green, Elisabeth P. Nacheva
Journal: Blood
Blood (2002) 99 (6): 2274–2275.
https://doi.org/10.1182/blood.V99.6.2274
Published: 2002