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Journal Articles

NPM1c Mutations Are Associated with Reduced Levels of Multiple Ribosome Biogenesis Factors Leading to Therapeutic Vulnerabilities

Aristi Damaskou, Rachael Wilson, Vijay Shanmugiah, Justyna Rak, Konstantinos Tzelepis, Berthold Gottgens, Malgorzata Gozdecka, George Vassiliou

Blood (2023) 142 (Supplement 1): 2743.

https://doi.org/10.1182/blood-2023-186084

Published: 2023

Journal Articles

Ancestry-Specific Genetic Determinants of Clonal Haematopoiesis: A Comparative Analysis of 136,401 Admixed Americans and 419,228 Europeans

Blood (2023) 142 (Supplement 1): 816.

https://doi.org/10.1182/blood-2023-173484

Published: 2023

Journal Articles

Polygenic Germline Risk of Common Haematological Traits Drives Clonal Selection on JAK2 V617F and Development of Myeloproliferative Neoplasms

Jyoti Nangalia, Jing Guo, Klaudia Walter, Pedro Quiros, Muxin Gu, E Joanna Baxter, John Danesh, Emanuele Di Angelantonio, David Roberts, Paola Guglielmelli, Claire N Harrison, Anna L Godfrey, Anthony R Green, George Vassiliou, Dragana Vuckovic, Nicole Soranzo

Blood (2023) 142 (Supplement 1): 863.

https://doi.org/10.1182/blood-2023-189551

Published: 2023

Journal Articles

Inactivation of DNA Polymerase Theta (PolΘ) Is Synthetic Lethal in DNMT3A Mutated Myeloid Malignancies - Potential Clinical Applications

Bac Viet Le, Umeshkumar Vekariya, Monika Toma, Margaret Nieborowska-Skorska, Marie-Christine Caron, George Vassiliou, Malgorzata Gozdecka, Zayd Haydar, Gurushankar Chandramouly, Emir Hadzijusufovic, Wolfgang R. Sperr, Richard Pomerantz, Peter Valent, Jean-Yves Masson, Gaorav Gupta, Grant A Challen, Tomasz Skorski

Blood (2023) 142 (Supplement 1): 580.

https://doi.org/10.1182/blood-2023-174333

Published: 2023

Journal Articles

Clonal Derivation and Dynamics in Rhesus Macaques Following Hematopoietic Stem Cell Transplantation and the Impact of Clonal Hematopoiesis

Yifan Zhou, Diana M Abraham, Taha Bartu Hayal, Ashley Laurel Gin, Xing Fan, Byung-Chul Lee, Taehoon Shin, Rohan V Hosuru, Elizabeth Lake Potter, So Gun Hong, Mario Roederer, George Vassiliou, Cynthia E. Dunbar, Chuanfeng Wu

Blood (2023) 142 (Supplement 1): 941.

https://doi.org/10.1182/blood-2023-180863

Published: 2023

Journal Articles

Machine Learning for Identification of High-Risk Clonal Haematopoiesis Using Blood Count Data

William G Dunn, Isabella Withnell, Muxin Gu, Pedro Quiros, Sruthi Cheloor Kovilakam, Ludovica Marando, Margarete Fabre, Irina Mohorianu, Dragana Vuckovic, George Vassiliou

Blood (2023) 142 (Supplement 1): 1318.

https://doi.org/10.1182/blood-2023-184721

Published: 2023

Journal Articles

Venetoclax synergizes with gilteritinib in FLT3 wild-type high-risk acute myeloid leukemia by suppressing MCL-1

Blood (2022) 140 (24): 2594–2610.

https://doi.org/10.1182/blood.2021014241

Published: 2022

Includes: Supplemental data

Journal Articles

Glutaminolysis is a metabolic dependency in FLT3 ITD acute myeloid leukemia unmasked by FLT3 tyrosine kinase inhibition

Paolo Gallipoli, George Giotopoulos, Konstantinos Tzelepis, Ana S. H. Costa, Shabana Vohra, Paula Medina-Perez, Faisal Basheer, Ludovica Marando, Lorena Di Lisio, Joao M. L. Dias, Haiyang Yun, Daniel Sasca, Sarah J. Horton, George Vassiliou, Christian Frezza, Brian J. P. Huntly

Blood (2018) 131 (15): 1639–1653.

https://doi.org/10.1182/blood-2017-12-820035

Published: 2018

Includes: Supplemental data

Journal Articles

R.I.S.C.L: A Holistic Molecular Diagnostic Tool for Myeloid Malignancies

Thomas D McKerrell, MD, Ignacio Varela, PhD, Nicolo Bolli, MD PhD, Postingl Hannes, PhD, Zemin Ning, PhD, German Tischler, PhD, Anthony Bench, PhD, Bridget Manasse, PhD, Joanna Baxter, PhD, Jorge Sierra, MD PhD, Dora Foukaneli, MD PhD, Allan Warren, MD PhD, Vincenza Colona, PhD, Chris Tyler-Smith, PhD, Brian Huntly, MD PhD, Josep F. Nomdedeu, MD, Mike Scott, PhD, George Vassiliou, MD PhD

Blood (2014) 124 (21): 2342.

https://doi.org/10.1182/blood.V124.21.2342.2342

Published: 2014

Journal Articles

Modelling Cellular and Molecular Progression Of CML In The Mouse

George Giotopoulos, Louise Van Der Weyden, Hikari Osaki, Wai-In Chan, Alistair Rust, Eshwar Meduri, Steffen Koschmieder, Daniel Tenen, George Vassiliou, David Adams, Brian Huntly

Blood (2013) 122 (21): 2706.

https://doi.org/10.1182/blood.V122.21.2706.2706

Published: 2013

Journal Articles

Histone deacetylase 1 and 2 are essential for normal T-cell development and genomic stability in mice

Oliver M. Dovey, Charles T. Foster, Nathalie Conte, Sally A. Edwards, Jennifer M. Edwards, Rajinder Singh, George Vassiliou, Allan Bradley, Shaun M. Cowley

Blood (2013) 121 (8): 1335–1344.

https://doi.org/10.1182/blood-2012-07-441949

Published: 2013

Includes: Supplemental data

Journal Articles

Activity of a Heptad of Transcription Factors Is Associated with Stem Cell Programs and Clinical Outcome in Acute Myeloid Leukaemia

Blood (2012) 120 (21): 3525.

https://doi.org/10.1182/blood.V120.21.3525.3525

Published: 2012

Journal Articles

JAK2 V617F Mutation Identifies a Biologically Distinct Subtype of Essential Thrombocythemia Which Resembles Polycythemia Vera.

Anthony Green, Peter Campbell, Linda Scott, Georgina Buck, Keith Wheatley, Clare East, Joanne Marsden, Audrey Duffy, Elaine Boyd, Anthony Bench, Mike Scott, George Vassiliou, Don Milligan, Steve Smith, Wendy Erber, David Bareford, Bridget Wilkins, John Reilly, Claire Harrison

Blood (2005) 106 (11): 253.

https://doi.org/10.1182/blood.V106.11.253.253

Published: 2005

Journal Articles

Imatinib improves but may not fully reverse the poor prognosis of patients with CML with derivative chromosome 9 deletions

Brian J. P. Huntly, Francois Guilhot, Alistair G. Reid, George Vassiliou, Evelin Hennig, Christina Franke, Jennie Byrne, Andre Brizard, Dietger Niederwieser, Julie Freeman-Edward, Gavin Cuthbert, Nick Bown, Richard E. Clark, Elizabeth P Nacheva, Anthony R Green, Michael W. N. Deininger

Blood (2003) 102 (6): 2205–2212.

https://doi.org/10.1182/blood-2002-09-2763

Published: 2003

NARROW

NPM1c Mutations Are Associated with Reduced Levels of Multiple Ribosome Biogenesis Factors Leading to Therapeutic Vulnerabilities

Ancestry-Specific Genetic Determinants of Clonal Haematopoiesis: A Comparative Analysis of 136,401 Admixed Americans and 419,228 Europeans

Polygenic Germline Risk of Common Haematological Traits Drives Clonal Selection on JAK2 V617F and Development of Myeloproliferative Neoplasms

Inactivation of DNA Polymerase Theta (PolΘ) Is Synthetic Lethal in DNMT3A Mutated Myeloid Malignancies - Potential Clinical Applications

Clonal Derivation and Dynamics in Rhesus Macaques Following Hematopoietic Stem Cell Transplantation and the Impact of Clonal Hematopoiesis

Machine Learning for Identification of High-Risk Clonal Haematopoiesis Using Blood Count Data

Venetoclax synergizes with gilteritinib in FLT3 wild-type high-risk acute myeloid leukemia by suppressing MCL-1

Glutaminolysis is a metabolic dependency in FLT3 ITD acute myeloid leukemia unmasked by FLT3 tyrosine kinase inhibition

R.I.S.C.L: A Holistic Molecular Diagnostic Tool for Myeloid Malignancies

Modelling Cellular and Molecular Progression Of CML In The Mouse

Histone deacetylase 1 and 2 are essential for normal T-cell development and genomic stability in mice

Activity of a Heptad of Transcription Factors Is Associated with Stem Cell Programs and Clinical Outcome in Acute Myeloid Leukaemia

JAK2 V617F Mutation Identifies a Biologically Distinct Subtype of Essential Thrombocythemia Which Resembles Polycythemia Vera.

Imatinib improves but may not fully reverse the poor prognosis of patients with CML with derivative chromosome 9 deletions

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American Society of Hematology

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American Society of Hematology

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