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Journal Articles

Disrupting tRNA modifications to target mitochondrial vulnerabilities in drug-resistant leukemia cells

Blood (2025) 146 (20): 2443–2456.

https://doi.org/10.1182/blood.2024027822

Published: 2025

Includes: Supplemental data

Journal Articles

The addition of a tyrosine kinase inhibitor to intensive chemotherapy significantly improves outcome in de novo BCR::ABL1+ acute myeloid leukemia treated with intensive chemotherapy

Sarah Bertoli, Niklas Landberg, Emilie Bérard, Camille Gondran, Laetitia Largeaud, Véronique De Mas, Pierre-Yves Dumas, Arnaud Pigneux, Audrey Bidet, Sylvain Garciaz, Ludovic Gabellier, Gabrielle Roth-Guepin, Corentin Orvain, Pierre Peterlin, Rudy Birsen, Magda Alexis, Martin Carre, Emmanuelle Tavernier, Marion Boissard Simonet, Chantal Himberlin, Marc Maynadié, Kamel Laribi, Cécile Moluçon-Chabrot, Amine Belhabri, Samy Chraibi, Quentin Cabrera, Delphine Lebon, Emmanuel Raffoux, Thomas Cluzeau, Jean-Baptiste Micol, Mathieu Leclerc, Céline Berthon, Herve Dombret, Gunnar Juliusson, Anna Robelius, Sören Lehmann, Martin Jädersten, Lovisa Wennström, Pau Montesinos, Carmen Botella, Juan Miguel Bergua Burgues, Raimundo Garcia, Josefina Serrano, Mariluz Amigo, Patricia Garcia Ramirez, Claudia Sossa, Juan Manuel Alonso-Dominguez, Hartmut Döhner, Konstanze Döhner, Daniela Späth, Michael Kühn, Claudia Lengerke, Hans-Jörg Tischler, Christoph Röllig, Leo Ruhnke, Christian Thiede, Andreas Burchert, Hubert Serve, Carsten Mueller-Tidow, Claudia Baldus, Jurjen Versluis, Peter Valk, Daniel Kristensen, Anne Stidsholt Roug, Jiri Mayer, Mika Kontro, Pia Ettala, Vladimir Lazarevic, Christian Recher

Blood (2025) 146 (Supplement 1): 991.

https://doi.org/10.1182/blood-2025-991

Published: 2025

Journal Articles

Baseline T-cell fitness and subtype-specific CD19 loss as drivers of blinatumomab resistance in B-ALL

Sonja Bendig, Miriam Kelm, Anna Laqua, Monika Szczepanowski, Thomas Beder, Nadine Wolgast, Mayukh Mondal, Malwine Barz, Alina Hartmann, Lars Fransecky, Jessica Stoldt, Nicola Gökbuget, Lorenz Bastian, Claudia Baldus, Monika Brüggemann, Guranda Chitadze

Blood (2025) 146 (Supplement 1): 32.

https://doi.org/10.1182/blood-2025-32

Published: 2025

Journal Articles

IL-1β-induced signaling modulates cytokine release and apoptosis in IDH1-mutant AML

Blood (2025) 146 (Supplement 1): 772.

https://doi.org/10.1182/blood-2025-772

Published: 2025

Journal Articles

RAS mutations are frequent in extramedullary AML and drive the tissue infiltration of leukemic cells via the induction of jaml

Blood (2025) 146 (Supplement 1): 659.

https://doi.org/10.1182/blood-2025-659

Published: 2025

Journal Articles

Venetoclax in combination with hypomethylating agents in adult patients with newly diagnosed AML with CBFB::MYH11 or RUNX1::RUNX1T1 fusions: Real-world outcomes based on international registry data

Blood (2025) 146 (Supplement 1): 5230.

https://doi.org/10.1182/blood-2025-5230

Published: 2025

Journal Articles

Single versus double “7+3” induction with 60 versus 90 mg/m2 daunorubicin in newly diagnosed AML: Does it matter for NPM1 MRD?

Blood (2025) 146 (Supplement 1): 5298.

https://doi.org/10.1182/blood-2025-5298

Published: 2025

Journal Articles

Venetoclax synergizes with gilteritinib in FLT3 wild-type high-risk acute myeloid leukemia by suppressing MCL-1

Blood (2022) 140 (24): 2594–2610.

https://doi.org/10.1182/blood.2021014241

Published: 2022

Includes: Supplemental data

Journal Articles

NPM1c alters FLT3-D835Y localization and signaling in acute myeloid leukemia

Alina Rudorf, Tony Andreas Müller, Cathrin Klingeberg, Stefanie Kreutmair, Teresa Poggio, Sivahari Prasad Gorantla, Tamina Rückert, Annette Schmitt-Graeff, Anina Gengenbacher, Peter Paschka, Claudia Baldus, Robert Zeiser, George S. Vassiliou, Allan Bradley, Justus Duyster, Anna Lena Illert

Blood (2019) 134 (4): 383–388.

https://doi.org/10.1182/blood.2018883140

Published: 2019

Includes: Supplemental data

Journal Articles

Quantitative Detection of DNMT3A R882H Mutation in Course of Treatment of Acute Myeloid Leukemia Patients

Olga Blau, MD PhD, Rimma Berenstein, Claudia Baldus, MD PhD, Nikola Suckert, Kathrin Rieger, MD, Axel Nogai, MD, Antonio Pezzutto, MD PhD, Bernd Doerken, MD PhD, Igor Wolfgang Blau, MD PhD

Blood (2015) 126 (23): 4970.

https://doi.org/10.1182/blood.V126.23.4970.4970

Published: 2015

Journal Articles

High Rate of FLT3 Mutations In Adult ETP-ALL.

Martin Neumann, Ebru Coskun, Ouidad Benlasfer, Sandra Heesch, Stefan Schwartz, MD, Nicola Goekbuget, MD, Dieter Hoelzer, MD, Wolf-Karsten Hofmann, MD, Eckhard Thiel, MD, Claudia Baldus, MD

Blood (2010) 116 (21): 1031.

https://doi.org/10.1182/blood.V116.21.1031.1031

Published: 2010

Journal Articles

Genome Wide Screening Reveals Distinct Signaling Pathways of the ETS Transcription Factor ERG In Primary Acute Leukemia Blasts

Juliane Bock, PhD, Liliana H. Mochmann, Stefanie Göllner, PhD, Eckhard Thiel, Prof., Dr., Dr., h.c., Carsten Müller-Tidow, MD, Claudia Baldus, PhD

Blood (2010) 116 (21): 4184.

https://doi.org/10.1182/blood.V116.21.4184.4184

Published: 2010

Journal Articles

Detection of Highly Clonal CD34 + , Mononuclear Bone Marrow and Peripheral Blood Cells From Patients with Myelodysplastic Syndrome and Age Related Increase of Clonal Hematopoiesis In Healthy Subjects Using a Novel Transcriptional Pyrosequencing Based Clonality Assay

Maximilian Mossner, Daniel Nowak, MD, Marion Klaumünzer, Verena Nowak, Katrin Ackermann, Susanne Brendel, Julia Obländer, Olaf Hopfer, Claudia Baldus, Eckhard Thiel, Wolf-Karsten Hofmann

Blood (2010) 116 (21): 977.

https://doi.org/10.1182/blood.V116.21.977.977

Published: 2010

Journal Articles

Sorafenib Monotherapy Is Effective In Relapsed and RefractoryFlt3-ITD Positive Acute Myeloid Leukemia, Particularly After Allogenic Stem Cell Transplantation

Blood (2010) 116 (21): 3314.

https://doi.org/10.1182/blood.V116.21.3314.3314

Published: 2010

Journal Articles

Antileukemic Activity of the HSP70 Inhibitor Pifithrin-μ

Martin Kaiser, Andrea Kuehnl, Jutta Ortiz-Tanchez, Ouidad Benlasfer, Cornelia Schlee, Sandra Heesch, Eckhard Thiel, Claudia Baldus

Blood (2010) 116 (21): 3306.

https://doi.org/10.1182/blood.V116.21.3306.3306

Published: 2010

Journal Articles

Low Expression of IL-15 in Adult B-Lineage Acute Lymphoblastic Leukemia Is Associated with Central Nervous System Involvement at Initial Presentation.

Shuling Wu, MD, Thomas Burmeister, MD, PhD, Claudia Baldus, MD, PhD, Stefen Schwartz, MD, Michael Notter, MD, Nicola Goekbuget, MD, Dieter Hoelzer, MD, Wolf K. Hofmann, MD, Eckhard Thiel, MD

Blood (2007) 110 (11): 2389.

https://doi.org/10.1182/blood.V110.11.2389.2389

Published: 2007

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Disrupting tRNA modifications to target mitochondrial vulnerabilities in drug-resistant leukemia cells

The addition of a tyrosine kinase inhibitor to intensive chemotherapy significantly improves outcome in de novo BCR::ABL1+ acute myeloid leukemia treated with intensive chemotherapy

Baseline T-cell fitness and subtype-specific CD19 loss as drivers of blinatumomab resistance in B-ALL

IL-1β-induced signaling modulates cytokine release and apoptosis in IDH1-mutant AML

RAS mutations are frequent in extramedullary AML and drive the tissue infiltration of leukemic cells via the induction of jaml

Venetoclax in combination with hypomethylating agents in adult patients with newly diagnosed AML with CBFB::MYH11 or RUNX1::RUNX1T1 fusions: Real-world outcomes based on international registry data

Single versus double “7+3” induction with 60 versus 90 mg/m2 daunorubicin in newly diagnosed AML: Does it matter for NPM1 MRD?

Venetoclax synergizes with gilteritinib in FLT3 wild-type high-risk acute myeloid leukemia by suppressing MCL-1

NPM1c alters FLT3-D835Y localization and signaling in acute myeloid leukemia

Quantitative Detection of DNMT3A R882H Mutation in Course of Treatment of Acute Myeloid Leukemia Patients

High Rate of FLT3 Mutations In Adult ETP-ALL.

Genome Wide Screening Reveals Distinct Signaling Pathways of the ETS Transcription Factor ERG In Primary Acute Leukemia Blasts

Detection of Highly Clonal CD34 + , Mononuclear Bone Marrow and Peripheral Blood Cells From Patients with Myelodysplastic Syndrome and Age Related Increase of Clonal Hematopoiesis In Healthy Subjects Using a Novel Transcriptional Pyrosequencing Based Clonality Assay

Sorafenib Monotherapy Is Effective In Relapsed and RefractoryFlt3-ITD Positive Acute Myeloid Leukemia, Particularly After Allogenic Stem Cell Transplantation

Antileukemic Activity of the HSP70 Inhibitor Pifithrin-μ

Low Expression of IL-15 in Adult B-Lineage Acute Lymphoblastic Leukemia Is Associated with Central Nervous System Involvement at Initial Presentation.

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