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Heinz Sill
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Journal Articles

Impact of Mono- and Bi-Allelic TP53 Aberrations on Transformation of Human HSPCs

Karin Lind, Sayantanee Dutta, Marco Cosenza, Thomas Eder, Johannes Foßelteder, Gabriel Pabst, Wolfgang Schöll, Andreas Prokesch, Andreas Reinisch, Albert Woelfler, Armin Zebisch, Florian Grebien, Jan O. Korbel, Heinz Sill
Journal: Blood
Blood (2024) 144 (Supplement 1): 5631.
https://doi.org/10.1182/blood-2024-203217
Published: 2024
Journal Articles

Cox Proportional Hazards Deep Neural Network Identifies Peripheral Blood Complete Remission (PB-CR) to be at Least Equivalent to Morphologic CR in Predicting Outcomes of Patients Treated with Azacitidine - a Prospective Cohort Study By the AGMT

Lisa Pleyer, Marc Vaisband, Michael Pfeilstocker, Reinhard Stauder, Sonja Heibl, Heinz Sill, Michael Girschikofsky, Margarete Stampfl-Mattersberger, Christoph Tinchon, Bernd L. Hartmann, Andreas Petzer, Martin Schreder, Clemens A. Schmitt, Sonia Vallet, Thomas Melchardt, Lukas Scagnetti, Armin Zebisch, Sigrid Machherndl-Spandl, Dominik Wolf, Felix Keil, Jan Hasenauer, Richard Greil
Journal: Blood
Blood (2022) 140 (Supplement 1): 1346–1349.
https://doi.org/10.1182/blood-2022-168521
Published: 2022
Journal Articles

Introduction and Genetic Correction of Calreticulin Mutations in Human Hematopoietic Stem and Progenitor Cells Sheds Light on MPN Pathogenesis

Johannes Foßelteder, Angelika Schlacher, Gabriel Pabst, Bettina Amtmann, Wolfgang Schöll, Karl Kashofer, Christine Beham-Schmid, Peter Schlenke, Hildegard T. Greinix, Heinz Sill, Albert Woelfler, Armin Zebisch, Andreas Reinisch
Journal: Blood
Blood (2021) 138 (Supplement 1): 2541.
https://doi.org/10.1182/blood-2021-147919
Published: 2021
Journal Articles

Peripheral Blood Complete Remission Provides Added Value to the Classical Definition of Morphologic Complete Remission - a Prospective Cohort Study of 1441 Patients with MDS, CMML and AML Treated within the Austrian Azacitidine Registry

Lisa Pleyer, Michael Pfeilstocker, Reinhard Stauder, Sonja Heibl, Heinz Sill, Michael Girschikofsky, Margarete Stampfl-Mattesberger, Christoph Tinchon, Bernd Hartmann, Andreas Petzer, Branka Petricevic, Clemens A. Schmitt, Sonja Vallet, Klaus Geissler, Wolfgang R. Sperr, Michael Leisch, Alexander Egle, Thomas Melchardt, Gudrun Piringer, Armin Zebisch, Sigrid Machherndl-Spandl, Dominik Wolf, Felix Keil, Hubert Angermann, Manuel Drost, Julian Larcher-Senn, Richard Greil
Journal: Blood
Blood (2021) 138 (Supplement 1): 3387.
https://doi.org/10.1182/blood-2021-145401
Published: 2021
Journal Articles

Modeling the Development of SRSF2 Mutated Myeloid Malignancies By CRISPR/Cas9 Mediated Genome Engineering of Primary Human Hematopoietic Stem and Progenitor Cells

Gabriel Pabst, Johannes Foßelteder, Angelika Schlacher, Lisa Auinger, Daniel Martinez-Krams, Asiri Ediriwickrema, Karl Kashofer, Christine Beham-Schmid, Hildegard T. Greinix, Albert Woelfler, Peter Schlenke, Heinz Sill, Armin Zebisch, Ravi Majeti, Andreas Reinisch
Journal: Blood
Blood (2021) 138 (Supplement 1): 2160.
https://doi.org/10.1182/blood-2021-149591
Published: 2021
Journal Articles

Phenotyping of Disease-Initiating CD34 + /CD38 ─ Stem Cells in BCR-ABL1 ─ MPN Reveals Expression of Multiple Cytokine Receptors and Resistance-Related Antigens

Daniel Ivanov, MSc, Jelena D. Milosevic Feenstra, PhD, Gregor Eisenwort, MD PhD, Robert Spörk, MSc, Alexandra Keller, PhD, Barbara Peter, Michael Willmann, Georg Greiner, Gabriele Stefanzl, Katharina Slavnitsch, Gregor Hoermann, Sybille Hofer, Wolfgang R. Sperr, MD, Heinz Sill, MD, Peter Bettelheim, MD, Klaus Geissler, MD, Elisabeth Koller, Michael Fillitz, MD, Michael Pfeilstocker, MD, Thomas Rülicke, Thamer Sliwa, MD, Felix Keil, MD, Robert Kralovics, PhD, Peter Valent, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 53.
https://doi.org/10.1182/blood-2020-140477
Published: 2020
Journal Articles

Core Binding Factor Leukemias Utilize a Physiologic Sense/Antisense Promoter Switch Employed By T-Cells

Emiel van der Kouwe, PharmD, Gerwin Heller, PhD, Akos Czibere, MD, Lucio H. Castilla, PhD, Ruud Delwel, PhD, Annalisa Di Ruscio, MD PhD, Alexander Ebralidze, PhD, Maurizio Forte, MSc, Lukas Kazianka, MD, Christoph Kornauth, Trang Le, BSc, Karin Lind, MSc, Ines Barbosa, PhD, Alexander Pichler, MD, John Pulikkan, PhD, Ann-Sofie Schmolke, MD, Heinz Sill, MD, Wolfgang R. Sperr, MD, Andreas Spittler, MD, Bon Q. Trinh, PhD, Peter Valent, MD, Katrina Vanura, PhD, Robert Welner, PhD, Johannes Zuber, PhD, Daniel G. Tenen, MD, Philipp B. Staber, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 40–41.
https://doi.org/10.1182/blood-2020-140776
Published: 2020
Journal Articles

Functional Classification of TP53 Mutations in Acute Myeloid Leukemia

Sayantanee Dutta, PhD, Gudrun Pregartner, Frank G. Rücker, MD, Ellen Heitzer, PhD, Armin Zebisch, MD, Lars Bullinger, Andrea Berghold, PhD, Konstanze Döhner, Heinz Sill, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2725.
https://doi.org/10.1182/blood-2019-124316
Published: 2019
Journal Articles

Expanding on Current Definitions of Hematologic Improvement in MDS, CMML and AML: Landmark Analyses of 1301 Patients Treated with Azacitidine in the Austrian Registry of Hypomethylating Agents By the AGMT-Study Group

Lisa Pleyer, Michael Pfeilstocker, MD, Reinhard Stauder, MD MSc, Sonja Heibl, MD, Heinz Sill, MD, Michael Girschikofsky, MD, Margarete Stampfl-Mattersberger, MD, Christoph Tinchon, MD, Andreas Petzer, MD, Clemens A. Schmitt, MD, Sonia Vallet, MD, Inga Mandac, MD, Klaus Geissler, MD, Wolfgang R. Sperr, MD, Michael Leisch, MD, Alexander Egle, MD, Thomas Melchardt, MD PhD, Julia Fusinato, BSc, Gudrun Piringer, MD MSc, Armin Zebisch, MD, Sigrid Machherndl-Spandl, MD, Dominik Wolf, MD, Felix Keil, MD, Richard Greil, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3821.
https://doi.org/10.1182/blood-2019-128153
Published: 2019
Journal Articles

Phenotypic Characterization of Leukemia-Initiating Stem Cells in Chronic Myelomonocytic Leukemia (CMML)

Gregor Eisenwort, MD PhD, Alexandra Keller, Michael Willmann, Irina Sadovnik, Greiner Georg, MD PhD, Karoline V. Gleixner, MD, Daniel Ivanov, MSc, Daniela Berger, Gabriele Stefanzl, Christiana Winding, DVM, Gregor Hoermann, Wolfgang R. Sperr, MD, Heinz Sill, MD, Peter Bettelheim, MD, Klaus Geissler, MD, Michael W. Deininger, Thomas Rülicke, Peter Valent, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4223.
https://doi.org/10.1182/blood-2019-122530
Published: 2019
Journal Articles

Functional Precision Medicine in AML: Technical Performance Evaluation for in Vitro Diagnostics Using High-Throughput Image-Based Screening of Primary Patient Cells

Nikolaus Krall, PhD, Noemi Meszaros, PhD, Karin Lind, MSc, Bojan Vilagos, PhD, Heinz Sill, MD, Gregory Ian Vladimer, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3366.
https://doi.org/10.1182/blood-2019-126609
Published: 2019
Journal Articles

Impact of TP53 Mutated Subclones in Acute Myeloid Leukemia

Gabriel Pabst, Katharina Prochazka, MD, Gudrun Pregartner, Frank G. Rücker, MD, Ellen Heitzer, PhD, Albert Woelfler, MD, Armin Zebisch, MD, Andrea Berghold, PhD, Konstanze Döhner, MD, Heinz Sill, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1483.
https://doi.org/10.1182/blood-2018-99-110667
Published: 2018
Journal Articles

Loss of RKIP is a frequent event in myeloid sarcoma and promotes leukemic tissue infiltration

Veronica Caraffini, Bianca Perfler, Johannes Lorenz Berg, Barbara Uhl, Silvia Schauer, Karl Kashofer, Nassim Ghaffari-Tabrizi-Wizsy, Herbert Strobl, Albert Wölfler, Gerald Hoefler, Heinz Sill, Armin Zebisch
Journal: Blood
Blood (2018) 131 (7): 826–830.
https://doi.org/10.1182/blood-2017-09-804906
Published: 2018
Includes: Supplemental data
Journal Articles

Real World Data on Decitabine Treatment in 296 Patients with Acute Myeloid Leukemia: Outcome and Impact of TP53 Mutations

Christoph Rollig, MD MSC, Jan Moritz Middeke, MD, Sebastian Stasik, Armin Zebisch, MD, Heinz Sill, MD, Michael Kramer, M.Sc., Sebastian Scholl, MD, Andreas Hochhaus, MD, Edgar Jost, Tim H. Brümmendorf, MD, Ralph Naumann, MD, Björn Steffen, Hubert Serve, Heidi Altmann, Volker Kunzmann, MD PhD, Hermann Einsele, Stefani Barbara Parmentier, MD, Markus Schaich, MD, Andreas Burchert, MD, Andreas Neubauer, MD, Frank Heits, MD, Wolfgang E. Berdel, Katja Sockel, MD, Friedrich Stoelzel, MD, Uwe Platzbecker, MD, Gerhard Ehninger, Martin Bornhäuser, MD, Johannes Schetelig, MD, Christian Thiede, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3896.
https://doi.org/10.1182/blood.V130.Suppl_1.3896.3896
Published: 2017
Journal Articles

Cytarabine dose in the consolidation treatment of AML: a systematic review and meta-analysis

Clinical Trials & Observations
Kinkini N. Magina, Gudrun Pregartner, Armin Zebisch, Albert Wölfler, Peter Neumeister, Hildegard T. Greinix, Andrea Berghold, Heinz Sill
Journal: Blood
Blood (2017) 130 (7): 946–948.
https://doi.org/10.1182/blood-2017-04-777722
Published: 2017
Includes: Supplemental data
Journal Articles

Somatic TP53 mutations characterize preleukemic stem cells in acute myeloid leukemia

Ridhima Lal, Karin Lind, Ellen Heitzer, Peter Ulz, Kristina Aubell, Karl Kashofer, Jan M. Middeke, Christian Thiede, Eduard Schulz, Angelika Rosenberger, Sybille Hofer, Birgit Feilhauer, Beate Rinner, Vendula Svendova, Michael G. Schimek, Frank G. Rücker, Gerald Hoefler, Konstanze Döhner, Armin Zebisch, Albert Wölfler, Heinz Sill
Journal: Blood
Blood (2017) 129 (18): 2587–2591.
https://doi.org/10.1182/blood-2016-11-751008
Published: 2017
Includes: Supplemental data
Journal Articles

90 Yttrium-Ibritumomab Tiuxetan as First Line Treatment for Follicular Non-Hodgkin Lymphoma. 5 Year Results from an International Multicenter Phase II Clinical Trial

Kristina Lerch, Corinna Leng, Antonello Pinto, Werner Linkesch, Heinz Sill, Ola Linden, Andreas Viardot, Ulrich Keller, Georg Hess, MD, Secondo Lastoria, Ferdinando Frigeri, Nicole Neik, Christiane Pott, Christian W. Scholz, Antonio Pezzutto, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1806.
https://doi.org/10.1182/blood.V128.22.1806.1806
Published: 2016
Journal Articles

High Spontaneous In Vitro Myeloid Colony Formation in Chronic Myelomonocytic Leukemia is Associated with Mutations in Rasopathy Genes, Myeloproliferation and Inferior Prognosis

Klaus Geissler, MD, Agnes Barna, MSc, Eva Jäger, BSc, Temeida Alendar, Elmir Ljubuncic, Ruth Jilch, MD, Thomas Nösslinger, MD, Michael Pfeilstöcker, MD, Heinz Tüchler, MD, Regina Reisner, MD, Thamer Sliwa, MD, Felix Keil, MD, Sonja Burgstaller, MD, Josef Thaler, MD, Sigrid Machherndl-Spandl, MD, Otto Zach, PhD, Ansgar Weltermann, MD, Peter Bettelheim, MD, Reinhard Stauder, MD, Ilse Schwarzinger, MD, Gregor Hörmann, MD, Ulrich Jäger, MD, Wolfgang R. Sperr, MD, Paul Knöbl, MD PhD, Bruno Schneeweiss, MD, Jörg Berger, MD, Rajko Kusec, MD PhD, Leopold Öhler, MD, Armin Zebisch, MD, Heinz Sill, Ulrich Germing, Peter Valent, MD
Journal: Blood
Blood (2016) 128 (22): 5503.
https://doi.org/10.1182/blood.V128.22.5503.5503
Published: 2016
Journal Articles

Clinical, Hematological, and Biologic Characteristics in Chronic Myelomonocytic Leukemia Patients with a JAK2 V617F Mutation

Klaus Geissler, MD, Agnes Barna, MSc, Eva Jäger, BSc, Temeida Alendar, Elmir Ljubuncic, Ruth Jilch, MD, Thomas Nösslinger, MD, Michael Pfeilstöcker, MD, Heinz Tüchler, MD, Regina Reisner, MD, Thamer Sliwa, MD, Felix Keil, MD, Sonja Burgstaller, MD, Josef Thaler, MD, Sigrid Machherndl-Spandl, MD, Otto Zach, PhD, Ansgar Weltermann, MD, Peter Bettelheim, MD, Reinhard Stauder, MD, Ilse Schwarzinger, MD, Gregor Hörmann, MD, Ulrich Jäger, MD, Wolfgang R. Sperr, MD, Paul Knöbl, MD PhD, Bruno Schneeweiss, MD, Jörg Berger, MD, Rajko Kusec, MD PhD, Leopold Öhler, MD, Armin Zebisch, MD, Heinz Sill, Ulrich Germing, Peter Valent, MD
Journal: Blood
Blood (2016) 128 (22): 3189.
https://doi.org/10.1182/blood.V128.22.3189.3189
Published: 2016
Journal Articles

Acute myeloid leukemia with TP53 germ line mutations

Armin Zebisch, Ridhima Lal, Marian Müller, Karin Lind, Karl Kashofer, Michael Girschikofsky, David Fuchs, Albert Wölfler, Jochen B. Geigl, Heinz Sill
Journal: Blood
Blood (2016) 128 (18): 2270–2272.
https://doi.org/10.1182/blood-2016-08-732610
Published: 2016
Includes: Supplemental data