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Journal Articles

Circulating Tumor DNA (ctDNA) Enables Superior and Universal Measurable Residual Disease (MRD) Monitoring in Acute Myeloid Leukemia (AML) Highly Predictive of Relapse Free and Overall Survival

Ruwan Gunaratne, Crystal Zhou, Jesse W. Tai, Sky Kim, Kailee Tanaka, Sanjeeth Rajaram, Mia Carleton, Raymond Yin, Matthew Alkaitis, Matthew Schwede, Brian J. Sworder, Michael S. Khodadoust, Ravi Majeti, David Kurtz, Tian Y Zhang

Blood (2024) 144 (Supplement 1): 2955.

https://doi.org/10.1182/blood-2024-201701

Published: 2024

Journal Articles

Dissecting Lineage and Cell State-Specific Epigenetic Evolution in Relapsed Acute Myeloid Leukemia

Armon Azizi, Kevin Nuno, Ravi Majeti

Blood (2023) 142 (Supplement 1): 5680.

https://doi.org/10.1182/blood-2023-180431

Published: 2023

Journal Articles

Cebpβ/IL1/TNFα Positive Feedback Loop Drives Drug Resistance of BCL2 and MDM2 Inhibitors in Monocytic Leukemia Cells

Basil Allen, Daniel Bottomly, Anthony Wang, Thomas Koehnke, Lindsey Savoy, Peter Ryabini, Reid Chen, Kara Johnson, Stephen E. Kurtz, Anupriya Agarwal, Michelle Barton, Brian J. Druker, Ravi Majeti, Jeffrey W Tyner, Shannon K McWeeney, Haijiao Zhang

Blood (2023) 142 (Supplement 1): 2937.

https://doi.org/10.1182/blood-2023-178096

Published: 2023

Journal Articles

Modeling the Development of SRSF2 Mutated Myeloid Malignancies By CRISPR/Cas9 Mediated Genome Engineering of Primary Human Hematopoietic Stem and Progenitor Cells

Gabriel Pabst, Johannes Foßelteder, Angelika Schlacher, Lisa Auinger, Daniel Martinez-Krams, Asiri Ediriwickrema, Karl Kashofer, Christine Beham-Schmid, Hildegard T. Greinix, Albert Woelfler, Peter Schlenke, Heinz Sill, Armin Zebisch, Ravi Majeti, Andreas Reinisch

Blood (2021) 138 (Supplement 1): 2160.

https://doi.org/10.1182/blood-2021-149591

Published: 2021

Journal Articles

Chromatin Accessibility Analysis Reveals Epigenetic Evolution Is a Common Mechanism of Relapse in Acute Myeloid Leukemia

Kevin A. Nuno, Armon Azizi, Thomas Koehnke, Asiri Ediriwickrema, M. Ryan Corces, Ravi Majeti

Blood (2021) 138 (Supplement 1): 677.

https://doi.org/10.1182/blood-2021-148928

Published: 2021

Journal Articles

Multi-Omic Analysis Identifies Epigenetic Evolution in Relapsed Acute Myeloid Leukemia

Kevin Nuno, BS, Armon Azizi, BS, Thomas Koehnke, MD, M. Ryan Corces, PhD, Ravi Majeti, MD PhD

Blood (2020) 136 (Supplement 1): 13–14.

https://doi.org/10.1182/blood-2020-143141

Published: 2020

Journal Articles

Shared Expression of CD93 and Other Antigens By AML and Endothelial Cells Highlights a Need for Rational Combinatorial Targeting

Rebecca M Richards, MDPhD, Feifei Zhao, Katherine A Murphy, Peng Xu, MD, Amy Fan, Elena Sotillo, PhD, Mads Daugaard, Htoo Zarni Oo, Jie Liu, Wan-Jen Hong, Poul Sorensen, Robbie G. Majzner, MD, Ravi Majeti, MD PhD, Crystal L. Mackall, MD

Blood (2020) 136 (Supplement 1): 22.

https://doi.org/10.1182/blood-2020-133988

Published: 2020

Journal Articles

Clonal Architecture and Variant Allele Frequency Predict Clinical Outcomes and Drug Response in Acute Myeloid Leukemia

Brooks Benard, BS, Logan Leak, BS, Armon Azizi, BS, Daniel Thomas, MD PhD, Andrew Gentles, PhD, Ravi Majeti, MD PhD

Blood (2020) 136 (Supplement 1): 2.

https://doi.org/10.1182/blood-2020-136477

Published: 2020

Journal Articles

An All Antibody Approach for Conditioning Bone Marrow for Hematopoietic Stem Cell Transplantation with Anti-cKIT and Anti-CD47 in Non-Human Primates

Kristopher D Marjon, PhD, James Y Chen, MD PhD, Jiaqi Duan, MS, Timothy S Choi, BS, Kavitha Sompalli, MS, Dongdong Feng, PhD, Ofelia Mata, Sharline Chen, B.S., Leslie Kean, MD PhD, Mwe Mwe Chao, MD, Mark Chao, MD PhD, Chris H Takimoto, MD PhD, Balaji Agoram, PhD, Cynthia E. Dunbar, MD, Ravi Majeti, MD PhD, Irving L Weissman, MD, Jie Liu, PhD MD, Jens-Peter Volkmer, MD

Blood (2019) 134 (Supplement_1): 4428.

https://doi.org/10.1182/blood-2019-131490

Published: 2019

Journal Articles

Induction of Truncating ASXL1 Mutations in Human CD34+ HSPCs Mimics Human ASXL1-Mutated Clonal Hematopoiesis and Progression to Myeloid Malignancies

Thomas Koehnke, MD, Rajiv Sharma, PhD, Yusuke Nakauchi, MD PhD, Andreas Reinisch, MD PhD, Ravi Majeti, MD PhD

Blood (2019) 134 (Supplement_1): 820.

https://doi.org/10.1182/blood-2019-130528

Published: 2019

Journal Articles

Biomarkers Predicting Venetoclax Sensitivity and Strategies for Venetoclax Combination Treatment

Haijiao Zhang, Beth Wilmot, PhD, Daniel Bottomly, Stephen E Kurtz, PhD, Christopher A. Eide, Alisa Damnernsawad, Kyle Romine, Shyam Patel, Brian J. Druker, MD, Schannon K Mcweeney, Ravi Majeti, MD PhD, Jeffrey W. Tyner, PhD

Blood (2018) 132 (Supplement 1): 175.

https://doi.org/10.1182/blood-2018-175

Published: 2018

Journal Articles

Combination Treatment with 5F9 and Azacitidine Enhances Phagocytic Elimination of Acute Myeloid Leukemia

Dongdong Feng, PhD, Phung Gip, PhD, Kelly Marie McKenna, BS, Feifei Zhao, Ofelia Mata, Timothy S Choi, BS, Jiaqi Duan, MS, Kavitha Sompalli, MS, Ravi Majeti, MD PhD, Irving L Weissman, MD, Chris H Takimoto, MD PhD, Mark Ping Chao, MD PhD, James Y Chen, MD PhD, Jie Liu, PhD MD, Jens-Peter Volkmer, MD

Blood (2018) 132 (Supplement 1): 2729.

https://doi.org/10.1182/blood-2018-99-120170

Published: 2018

Journal Articles

The Origin and Functional Impact of Mitochondrial DNA Mutations in Acute Myeloid Leukemia

Severine Cathelin, PhD, David Sharon, PhD, Michael Ryan Corces-Zimmerman, PhD, Bruno C Medeiros, MD, Ravi Majeti, MD PhD, Steven M. Chan, MDPhD

Blood (2017) 130 (Supplement 1): 2496.

https://doi.org/10.1182/blood.V130.Suppl_1.2496.2496

Published: 2017

Journal Articles

A Novel Model of Human Hemopoiesis Based on Single Cell Functional and Transcriptional Analysis of Lympho-Myeloid Progenitors

Blood (2017) 130 (Supplement 1): 2413.

https://doi.org/10.1182/blood.V130.Suppl_1.2413.2413

Published: 2017

Journal Articles

Characterization and Targeting TET2-Mutant HSPCs and AML

Yusuke Nakauchi, MD PhD, Daniel Thomas, MD PhD, Andreas Reinisch, MD PhD, Rajiv Sharma, PhD, David Cruz, BS, M. Ryan Corces, PhD, Ravi Majeti, MD PhD

Blood (2017) 130 (Supplement 1): 2509.

https://doi.org/10.1182/blood.V130.Suppl_1.2509.2509

Published: 2017

Journal Articles

Pluripotent Reprogramming of Human AML Resets Leukemic Behavior and Models Therapeutic Targeting of Subclones

Mark Ping Chao, MD PhD, Gentles Andrew, PhD, Chatterjee Susmita, MS, Andreas Reinisch, MDPhD, M. Ryan Corces, PhD, Jinfeng Shen, PhD, Morganti Rachel, Rahul Singha, PhD, Daniel Haag, PhD, Marius Wernig, PhD, Joseph Wu, MD PhD, Ravi Majeti, MD PhD

Blood (2016) 128 (22): 575.

https://doi.org/10.1182/blood.V128.22.575.575

Published: 2016

Journal Articles

Isocitrate Dehydrogenase 1 Mutant Cancers Are Metabolically Vulnerable to Inhibition of Acetyl CoA Carboxylase Via a 2-Hydroxyglutarate Independent Mechanism

Daniel Thomas, MD PhD, Subarna Sinha, PhD, Steven M. Chan, MD PhD, Manhong Wu, Damoun Torabi, Gary Peltz, MD PhD, Yang Gao, David L Dill, PhD, Ravi Majeti, MD PhD

Blood (2016) 128 (22): 1054.

https://doi.org/10.1182/blood.V128.22.1054.1054

Published: 2016

Journal Articles

Boolean Implication Mining for Synthetic Lethal Interactions in AML Identifies Acetyl-CoA Carboxylase As a Synthetic Lethal Partner of the IDH1 mutation

Subarna Sinha, PhD, Daniel Thomas, MD PhD, Steven M. Chan, MD PhD, Yang Gao, Rolf Jansen, PhD, Ravi Majeti, MD PhD, David L Dill, PhD

Blood (2015) 126 (23): 1404.

https://doi.org/10.1182/blood.V126.23.1404.1404

Published: 2015

Journal Articles

Clonal Evolution of Pre-Leukemic Hematopoietic Stem Cells in Human Acute Myeloid Leukemia

Ravi Majeti, MD PhD

Blood (2015) 126 (23): SCI-11.

https://doi.org/10.1182/blood.V126.23.SCI-11.SCI-11

Published: 2015

Journal Articles

Leukemia-Associated Cohesin Mutants Dominantly Enforce Stem Cell Programs and Impair Human Hematopoietic Progenitor Differentiation

Claire Mazumdar, Ying Shen, Seethu Xavy, Feifei Zhao, Andreas Reinisch, MDPhD, Rui Li, Michael Ryan Corces-Zimmerman, PhD, Jason Buenrostro, Steven M. Chan, MD PhD, Daniel Thomas, MD PhD, Julie Koenig, Wan-Jen Hong, MD, Howard Chang, MD PhD, Ravi Majeti, MD PhD

Blood (2015) 126 (23): 841.

https://doi.org/10.1182/blood.V126.23.841.841

Published: 2015

NARROW

Circulating Tumor DNA (ctDNA) Enables Superior and Universal Measurable Residual Disease (MRD) Monitoring in Acute Myeloid Leukemia (AML) Highly Predictive of Relapse Free and Overall Survival

Dissecting Lineage and Cell State-Specific Epigenetic Evolution in Relapsed Acute Myeloid Leukemia

Cebpβ/IL1/TNFα Positive Feedback Loop Drives Drug Resistance of BCL2 and MDM2 Inhibitors in Monocytic Leukemia Cells

Modeling the Development of SRSF2 Mutated Myeloid Malignancies By CRISPR/Cas9 Mediated Genome Engineering of Primary Human Hematopoietic Stem and Progenitor Cells

Chromatin Accessibility Analysis Reveals Epigenetic Evolution Is a Common Mechanism of Relapse in Acute Myeloid Leukemia

Multi-Omic Analysis Identifies Epigenetic Evolution in Relapsed Acute Myeloid Leukemia

Shared Expression of CD93 and Other Antigens By AML and Endothelial Cells Highlights a Need for Rational Combinatorial Targeting

Clonal Architecture and Variant Allele Frequency Predict Clinical Outcomes and Drug Response in Acute Myeloid Leukemia

An All Antibody Approach for Conditioning Bone Marrow for Hematopoietic Stem Cell Transplantation with Anti-cKIT and Anti-CD47 in Non-Human Primates

Induction of Truncating ASXL1 Mutations in Human CD34+ HSPCs Mimics Human ASXL1-Mutated Clonal Hematopoiesis and Progression to Myeloid Malignancies

Biomarkers Predicting Venetoclax Sensitivity and Strategies for Venetoclax Combination Treatment

Combination Treatment with 5F9 and Azacitidine Enhances Phagocytic Elimination of Acute Myeloid Leukemia

The Origin and Functional Impact of Mitochondrial DNA Mutations in Acute Myeloid Leukemia

A Novel Model of Human Hemopoiesis Based on Single Cell Functional and Transcriptional Analysis of Lympho-Myeloid Progenitors

Characterization and Targeting TET2-Mutant HSPCs and AML

Pluripotent Reprogramming of Human AML Resets Leukemic Behavior and Models Therapeutic Targeting of Subclones

Isocitrate Dehydrogenase 1 Mutant Cancers Are Metabolically Vulnerable to Inhibition of Acetyl CoA Carboxylase Via a 2-Hydroxyglutarate Independent Mechanism

Boolean Implication Mining for Synthetic Lethal Interactions in AML Identifies Acetyl-CoA Carboxylase As a Synthetic Lethal Partner of the IDH1 mutation

Clonal Evolution of Pre-Leukemic Hematopoietic Stem Cells in Human Acute Myeloid Leukemia

Leukemia-Associated Cohesin Mutants Dominantly Enforce Stem Cell Programs and Impair Human Hematopoietic Progenitor Differentiation

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American Society of Hematology

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ASH Publications

American Society of Hematology

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