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Journal Articles

Human HSPCs CRISPR-engineered to endogenously express oncogenic NRAS generate a transplantable lethal myeloid malignancy targetable with novel RAS therapeutics

Free
Shirley Liu, Cailin Collins, James Chavez, Suyoun Choi, Thomas Koehnke, Ravi Majeti
Journal: Blood
Blood (2025) 146 (Supplement 1): 5004.
https://doi.org/10.1182/blood-2025-5004
Published: 2025
Journal Articles

Single-Cell RNA Sequencing Reveals the Interplay between Circulating CD4 + T Cells, B Cells and Cancer-Associated Monocytes in Classic Hodgkin Lymphoma Treated with PD-1 Blockade

Free
Julia Paczkowska, Ming Tang, Kyle T. Wright, Li Song, Kelsey Luu, Vignesh Shanmugam, Emma L. Welsh, Jason L. Weirather, Kathleen Pfaff, Robert A. Redd, Zumla Cader, Elisa Mandato, Jing Ouyang, Gali Bai, Lee N. Lawton, Philippe Armand, Scott Rodig, Xiaole Shirley Liu, Margaret A. Shipp
Journal: Blood
Blood (2023) 142 (Supplement 1): 173.
https://doi.org/10.1182/blood-2023-187038
Published: 2023
Journal Articles

Molecular and cellular features of CTLA-4 blockade for relapsed myeloid malignancies after transplantation

Free
Clinical Trials & Observations Brief Report
Livius Penter, Yi Zhang, Alexandra Savell, Teddy Huang, Nicoletta Cieri, Emily M. Thrash, Seunghee Kim-Schulze, Aashna Jhaveri, Jingxin Fu, Srinika Ranasinghe, Shuqiang Li, Wandi Zhang, Emma S. Hathaway, Matthew Nazzaro, Haesook T. Kim, Helen Chen, Magdalena Thurin, Scott J. Rodig, Mariano Severgnini, Carrie Cibulskis, Stacey Gabriel, Kenneth J. Livak, Corey Cutler, Joseph H. Antin, Sarah Nikiforow, John Koreth, Vincent T. Ho, Philippe Armand, Jerome Ritz, Howard Streicher, Donna Neuberg, F. Stephen Hodi, Sacha Gnjatic, Robert J. Soiffer, X. Shirley Liu, Matthew S. Davids, Pavan Bachireddy, Catherine J. Wu
Journal: Blood
Blood (2021) 137 (23): 3212–3217.
https://doi.org/10.1182/blood.2021010867
Published: 2021
Includes: Supplemental data
Journal Articles

Local and Systemic Effects of Immune Checkpoint Blockade on Relapsed Myeloid Malignancies Following Allogeneic Hematopoietic Stem Cell Transplantation

Free
Livius Penter, Yi Zhang, PhD, Alexandra Savell, BS, Srinika Ranasinghe, PhD, Teddy Huang, BS, Nicoletta Cieri, MD PhD, Satyen H Gohil, PhD MB, BS, Wandi Zhang, BS, Shuqiang Li, PhD, Robert Zeiser, PhD, Haesook T. Kim, PhD, Kenneth J. Livak, PhD, Jerome Ritz, MD, Donna S. Neuberg, ScD, Robert J. Soiffer, MD, X. Shirley Liu, PhD, Matthew S. Davids, MD, Pavan Bachireddy, MD, Catherine J. Wu, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 34–35.
https://doi.org/10.1182/blood-2020-139487
Published: 2020
Journal Articles

The Lysine Histone Methyltransferase SETD2 Is Required for Appropriate Immunoglobulin VDJ Recombination

Free
S. Haihua Chu, PhD, Jonathan Chabon, BS, Janna Minehart, BS, Chloe N Matovina, BS, Jian Zhang, Bo-Ruei Chen, PhD, Elsa Callen-Moreu, PhD, Putzer J Hung, Zhaohui Feng, BM, BS, Richard Koche, PhD, X. Shirley Liu, Jayanta Chaudhuri, Andre Nussenzweig, PhD, Barry Sleckman, Scott A. Armstrong, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 511.
https://doi.org/10.1182/blood-2018-99-111952
Published: 2018
Journal Articles

Mass cytometry of Hodgkin lymphoma reveals a CD4 + regulatory T-cell–rich and exhausted T-effector microenvironment

Free
Fathima Zumla Cader, Ron C. J. Schackmann, Xihao Hu, Kirsty Wienand, Robert Redd, Bjoern Chapuy, Jing Ouyang, Nicole Paul, Evisa Gjini, Mikel Lipschitz, Philippe Armand, David Wu, Jonathan R. Fromm, Donna Neuberg, X. Shirley Liu, Scott J. Rodig, Margaret A. Shipp
Journal: Blood
Blood (2018) 132 (8): 825–836.
https://doi.org/10.1182/blood-2018-04-843714
Published: 2018
Includes: Multimedia, Supplemental data
Journal Articles

Topological analysis reveals a PD-L1-associated microenvironmental niche for Reed-Sternberg cells in Hodgkin lymphoma

Free
Christopher D. Carey, Daniel Gusenleitner, Mikel Lipschitz, Margaretha G. M. Roemer, Edward C. Stack, Evisa Gjini, Xihao Hu, Robert Redd, Gordon J. Freeman, Donna Neuberg, F. Stephen Hodi, Xiaole Shirley Liu, Margaret A. Shipp, Scott J. Rodig
Journal: Blood
Blood (2017) 130 (22): 2420–2430.
https://doi.org/10.1182/blood-2017-03-770719
Published: 2017
Includes: Supplemental data
Journal Articles

Alternative Super-Enhancer States Determine MYC Sensitivity to Notch and Brd4 Inhibitors in T Lymphoblastic Leukemia/Lymphoma

Free
Hongfang Wang, PhD, Yumi Yashiro-Ohtani, PhD, Chongzhi Zang, PhD, Yinling Joey Wong, MS, Will Bailis, PhD, Birgit Knoechel, MD PhD, Bradley Bernstein, MD PhD, Steve Blacklow, MD PhD, X. Shirley Liu, PhD, Warren S. Pear, MD PhD, Jon C Aster, MD PhD
Journal: Blood
Blood (2014) 124 (21): 863.
https://doi.org/10.1182/blood.V124.21.863.863
Published: 2014
Journal Articles

Genome-Wide Analysis of NOTCH1, ETS Family Factors, and RUNX1 Binding in Human T Lymphoblastic Leukemia Cells Reveals Distinct Regulatory Elements

Free
Hongfang Wang, PhD, Chongzhi Zang, Ph.D, Len Taing, Hoifung Wong, Yumi Yashiro-Ohtani, Ph.D., Stephen Blacklow, MD. PhD., Warren S. Pear, MD, PhD, X. Shirley Liu, Ph.D, Jon C Aster, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 1277.
https://doi.org/10.1182/blood.V120.21.1277.1277
Published: 2012
Journal Articles

Impaired Hydroxylation of 5-Methylcytosine In TET2 mutated Patients with Myeloid Malignancies

Free
Anna Jankowska, Myunggon Ko, Yun Huang (equal contribution), Utz J. Pape, Hadrian Szpurka, Mamta Tahiliani, Hozefa S. Bandukwala, Jungeun An, Edward D. Lamperti, Kian Peng Koh, X. Shirley Liu, L. Aravind, Suneet Agarwal, Anjana Rao, PhD, Jaroslaw P Maciejewski, MD, PhD, FACP
Journal: Blood
Blood (2010) 116 (21): 1.
https://doi.org/10.1182/blood.V116.21.1.1
Published: 2010
Journal Articles

Transcriptional regulatory networks downstream of TAL1/SCL in T-cell acute lymphoblastic leukemia

Free
Teresa Palomero, Duncan T. Odom, Jennifer O'Neil, Adolfo A. Ferrando, Adam Margolin, Donna S. Neuberg, Stuart S. Winter, Richard S. Larson, Wei Li, X. Shirley Liu, Richard A. Young, A. Thomas Look
Journal: Blood
Blood (2006) 108 (3): 986–992.
https://doi.org/10.1182/blood-2005-08-3482
Published: 2006
Includes: Supplemental data