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Lee N. Lawton
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Journal Articles

Single-Cell RNA Sequencing Reveals the Interplay between Circulating CD4 + T Cells, B Cells and Cancer-Associated Monocytes in Classic Hodgkin Lymphoma Treated with PD-1 Blockade

Julia Paczkowska, Ming Tang, Kyle T. Wright, Li Song, Kelsey Luu, Vignesh Shanmugam, Emma L. Welsh, Jason L. Weirather, Kathleen Pfaff, Robert A. Redd, Zumla Cader, Elisa Mandato, Jing Ouyang, Gali Bai, Lee N. Lawton, Philippe Armand, Scott Rodig, Xiaole Shirley Liu, Margaret A. Shipp
Journal: Blood
Blood (2023) 142 (Supplement 1): 173.
https://doi.org/10.1182/blood-2023-187038
Published: 2023
Journal Articles

Genetic Perturbation of CD70/CD27 Co-Stimulation Promotes the Development of Bcl6 -Driven Diffuse Large B-Cell Lymphoma

Elisa Mandato, Yanbo Sun, Vignesh Shanmugam, Il-Kyu Choi, Kyle T. Wright, Robert A. Redd, Lee N. Lawton, Donna S. Neuberg, Scott J. Rodig, Baochun Zhang, Margaret A. Shipp
Journal: Blood
Blood (2021) 138 (Supplement 1): 713.
https://doi.org/10.1182/blood-2021-153533
Published: 2021
Journal Articles

MYD88 L265P Augments Proximal B-Cell Receptor Signaling in Large B-Cell Lymphomas Via an Interaction with DOCK8

Elisa Mandato, Qingsheng Yan, Jing Ouyang, Julia Paczkowska, Yan Qin, Yansheng Hao, Kamil Bojarczuk, Julia Hansen, Lee N. Lawton, Margaret A. Shipp
Journal: Blood
Blood (2021) 138 (Supplement 1): 1324.
https://doi.org/10.1182/blood-2021-153024
Published: 2021
Journal Articles

Comparative Genomic Analyses Defines Shared and Unique Features of cHL and PMBL and New Mechanisms of Sensitivity to PD-1 Blockade

Kirsty Wienand, PhD, Bjoern Chapuy, MD PhD, Chip Stewart, PhD, Andrew Dunford, MS, David Wu, MD PhD, Jaegil Kim, PhD, Atanas Kamburov, PhD, Timothy Wood, Fathima Zumla Cader, MD PhD MRCP, Matthew D. Ducar, MS, Aaron R. Thorner, PhD, Anwesha Nag, PhD, Gabriel K Griffin, MD, Pei-Hsuan Chen, Alexander T Heubeck, BS, Michael J Buonopane, BS, Kamil Bojarczuk, PhD, Claire McEwen Cote, Lee N. Lawton, PhD, Philippe Armand, MD PhD, Scott J Rodig, MD PhD, Jonathan R. Fromm, MD PhD, Gad Getz, PhD, Margaret A. Shipp, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1493.
https://doi.org/10.1182/blood-2019-131904
Published: 2019
Journal Articles

Targeted inhibition of PI3Kα/δ is synergistic with BCL-2 blockade in genetically defined subtypes of DLBCL

Kamil Bojarczuk, Kirsty Wienand, Jeremy A. Ryan, Linfeng Chen, Mariana Villalobos-Ortiz, Elisa Mandato, Joanna Stachura, Anthony Letai, Lee N. Lawton, Bjoern Chapuy, Margaret A. Shipp
Journal: Blood
Blood (2019) 133 (1): 70–80.
https://doi.org/10.1182/blood-2018-08-872465
Published: 2019
Includes: Supplemental data
Journal Articles

Targeted Inhibition of PI3K α/δ Is Synergistic with BCL-2 Blockade in Genetically Defined Subtypes of DLBCL

Kamil Bojarczuk, PhD, Kirsty Wienand, PhD, Jeremy A. Ryan, SM, Linfeng Chen, PhD, Mariana Villalobos-Ortiz, Elisa Mandato, PhD, Joanna Stachura, MSc, Lee N. Lawton, PhD, Anthony Letai, MD PhD, Bjoern Chapuy, MDPhD, Margaret A. Shipp, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 39.
https://doi.org/10.1182/blood-2018-99-113647
Published: 2018
Journal Articles

ARID5B Activates the TAL1-Induced Core Regulatory Circuit and the MYC Oncogene in T-Cell Acute Lymphoblastic Leukemia

Wei Zhong Leong, BSc, Shi Hao Tan, PhD, Phuong Cao Thi Ngoc, PhD, Stella Amanda, Alice Wei Yee Yam, Wei-Siang Liau, Zhiyuan Gong, Lee N. Lawton, PhD, Daniel G. Tenen, MD, Takaomi Sanda, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2502.
https://doi.org/10.1182/blood.V130.Suppl_1.2502.2502
Published: 2017
Journal Articles

The TAL1 Complex Represses the FBXW7 Tumor Suppressor Through Mir-223 in Human T-Cell Acute Lymphoblastic Leukemia

Marc R Mansour, MD FRCPath, Takaomi Sanda, MD, PhD, Lee N Lawton, PhD, Xiaoyu Li, MD, PhD, Taras Kreslavsky, PhD, Carl Novina, MD PhD, Harald von Boehmer, MD PhD, Richard Young, PhD, A. Thomas Look, M.D.
Journal: Blood
Blood (2012) 120 (21): 1296.
https://doi.org/10.1182/blood.V120.21.1296.1296
Published: 2012
Journal Articles

Lineage Regulators Direct BMP and Wnt Pathways to Cell-Specific Programs During Differentiation and Regeneration,

Teresa V. Bowman, PhD, Eirini Trompouki, PhD, Lee N Lawton, PhD, Zi Peng Fan, Dai-chen Wu, Anthony DiBiase, Corey S Martin, Jennifer N Cech, Anna K Sessa, Jocelyn L LeBlanc, Pulin Li, Ellen Durand, Christian Mosimann, Garrett C Heffner, PhD, George Q. Daley, MD, PhD, Robert F. Paulson, PhD, BA, Richard Young, PhD, Leonard I. Zon, MD
Journal: Blood
Blood (2011) 118 (21): 3387.
https://doi.org/10.1182/blood.V118.21.3387.3387
Published: 2011
Journal Articles

Core Transcriptional Regulatory Circuit Controlled by the TAL1 Complex in T-Cell Acute Lymphoblastic Leukemia,

Takaomi Sanda, M.D., Ph.D., Lee N Lawton, PhD, M Inmaculada Barrasa, Ph.D., Zi Peng Fan, Yebin Ahn, Richard Young, PhD, A. Thomas Look, M.D.
Journal: Blood
Blood (2011) 118 (21): 3453.
https://doi.org/10.1182/blood.V118.21.3453.3453
Published: 2011
Journal Articles

BMP and WNT-Directed Transcription Factors TCF7L2/TCF4 and SMAD1 Bind to Distinct Hematopoietic-Specific Target Genes Depending on Cell Lineage

Eirini Trompouki, PhD, Teresa V. Bowman, PhD, Lee N Lawton, PhD, Zi Peng Fan, Anthony DiBiase, Jennifer Cech, Anna Sessa, Jocelyn LeBlanc, Pulin Li, Garrett Heffner, PhD, George Q. Daley, MD, PhD, Richard Young, PhD, Leonard I. Zon, MD
Journal: Blood
Blood (2010) 116 (21): 3870.
https://doi.org/10.1182/blood.V116.21.3870.3870
Published: 2010