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Journal Articles

Single-Cell RNA Sequencing Reveals the Interplay between Circulating CD4 + T Cells, B Cells and Cancer-Associated Monocytes in Classic Hodgkin Lymphoma Treated with PD-1 Blockade

Julia Paczkowska, Ming Tang, Kyle T. Wright, Li Song, Kelsey Luu, Vignesh Shanmugam, Emma L. Welsh, Jason L. Weirather, Kathleen Pfaff, Robert A. Redd, Zumla Cader, Elisa Mandato, Jing Ouyang, Gali Bai, Lee N. Lawton, Philippe Armand, Scott Rodig, Xiaole Shirley Liu, Margaret A. Shipp
Journal: Blood
Blood (2023) 142 (Supplement 1): 173.
https://doi.org/10.1182/blood-2023-187038
Published: 2023
Journal Articles

Genome-Scale High-Resolution Spatial Mapping of the Pro-Tumorigenic Cellular Niche in Classic Hodgkin Lymphoma

Vignesh Shanmugam, Neriman Tokcan, Daniel Chafamo, Sean Sullivan, Haley Martin, Gail A Newton, Mehdi Borji, Naeem Nadaf, Irving Barrera, Dylan Cable, Jackson Weir, Orr Ashenberg, Caroline Uhler, Geraldine Pinkus, Scott Rodig, Margaret A. Shipp, Evan Macosko, Abner Louissaint, Fei Chen, Todd R. Golub
Journal: Blood
Blood (2023) 142 (Supplement 1): 175.
https://doi.org/10.1182/blood-2023-185522
Published: 2023
Journal Articles

Cd70 Deficiency Impairs CD4 + and CD8 + T-Cell Immune Surveillance in Bcl6 -Driven Diffuse Large B-Cell Lymphomas

Elisa Mandato, Eleonora Calabretta, Gali Bai, Li Song, Tianfang Ma, Vignesh Shanmugam, Julia Paczkowska, Yanbo Sun, Il-Kyu Choi, Robert A. Redd, Donna S. Neuberg, Sumbul Jawed Khan, Franziska Michor, Scott Rodig, Baochun Zhang, Margaret A. Shipp
Journal: Blood
Blood (2023) 142 (Supplement 1): 1624.
https://doi.org/10.1182/blood-2023-186297
Published: 2023
Journal Articles

Baseline Immune State and T Cell Clonal Kinetics Are Associated with Response to CAR-T Therapy in Large B-Cell Lymphoma

Katie Maurer, Isabella N. Grabski, Roch Houot, Satyen H Gohil, Shogo Miura, Robert A. Redd, Haoxiang Lyu, Wesley S Lu, Brodie Miles, Mike Mattie, Yohei Arihara, Mikaela M. McDonough, Carol Reynolds, Michela Ansuinelli, Shuqiang Li, Kenneth J. Livak, Jerome Ritz, Scott Rodig, Rafael A. Irizarry, Philippe Armand, Catherine J Wu, Caron A. Jacobson
Journal: Blood
Blood (2023) 142 (Supplement 1): 223.
https://doi.org/10.1182/blood-2023-180819
Published: 2023
Journal Articles

Safety and Efficacy of Decitabine Plus Ipilimumab in Relapsed or Refractory MDS/AML in the Post-BMT or Transplant Naïve Settings

Jacqueline S. Garcia, MD, Yael Flamand, MS, Benjamin K. Tomlinson, MD, Michael Keng, MD, Lourdes M. Mendez, MD PhD, Samer Khaled, MD, Asad Bashey, MD PhD, Andrew M. Brunner, MD, Alexandra Savell, BS, Donna Neuberg, Ilene Galinsky, Marlise R. Luskin, MD, David P. Steensma, MD, Martha Wadleigh, MD, Eric S. Winer, MD, David E. Avigan, MD, Nicole Cullen, Scott Rodig, MD PhD, Livius Penter, R. Coleman Lindsley, MD PhD, Stephanie Andrews, Matthew S. Davids, MD, Catherine J. Wu, MD, Richard M. Stone, MD, Daniel J. DeAngelo, MD PhD, Robert J. Soiffer, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 15–17.
https://doi.org/10.1182/blood-2020-136235
Published: 2020
Journal Articles

Title: Clinical and Biological Evaluation of the Novel CD30/CD16A Tetravalent Bispecific Antibody (AFM13) in Relapsed or Refractory CD30-Positive Lymphoma with Cutaneous Presentation: A Biomarker Phase Ib/IIa Study (NCT03192202)

Ahmed Sawas, MD, Pei-Hsuan Chen, Mikel Lipschitz, M.S., Scott Rodig, MD PhD, George Vlad
Journal: Blood
Blood (2020) 136 (Supplement 1): 25–26.
https://doi.org/10.1182/blood-2020-140096
Published: 2020
Journal Articles

Clinical and Immunologic Activity of Ipilimumab Following Decitabine Priming in Post-Allogeneic Transplant and Transplant-Naïve Patients with Relapsed or Refractory Myelodysplastic Syndromes and Acute Myeloid Leukemia: A Multi-Center Phase 1, Two-Arm, Dose-Escalation Study

Jacqueline S Garcia, MD, Lillian Werner, Benjamin K. Tomlinson, MD, Michael Keng, MD, Myrna Nahas, MD, Andrew Brunner, MD, Samer K. Khaled, MD, Alexandra Savell, BS, Marlise Luskin, MDMS, David P. Steensma, MD, Martha Wadleigh, MD, Eric S. Winer, MD, Edwin P. Alyea, III, MD, Corey Cutler, MD MPH, FRCPC, Vincent T. Ho, MD, Donna S Neuberg, ScD, Nicole Cullen, Andreas Kantartzis, Ana Lako, Scott Rodig, MD PhD, R. Coleman Lindsley, MD PhD, Yael Flamand, Claire Manuszak, Ryan Brennick, Mariano Severgnini, Stephanie Andrews, Ilene Galinsky, Pavan Bachireddy, MD, Yohei Arihara, MD PhD, Jerome Ritz, MD, Matthew S. Davids, MD, Howard Streicher, MD, Catherine J. Wu, MD, Richard M. Stone, MD, Daniel J. DeAngelo, MD, Robert J. Soiffer, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2015.
https://doi.org/10.1182/blood-2019-126238
Published: 2019
Journal Articles

Alterations In Mitochondrial Priming May Be a Mechanism For Acquired Resistance To Therapy In Diffuse Large B-Cell Lymphoma

Elizabeth Brem, MD, Francisco J. Hernandez-Ilizaliturri, MD, Myron S. Czuczman, MD, Scott Rodig, M.D., Ph.D., Anthony G. Letai, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 1764.
https://doi.org/10.1182/blood.V122.21.1764.1764
Published: 2013
Journal Articles

Results of a phase 2 trial of the single-agent histone deacetylase inhibitor panobinostat in patients with relapsed/refractory Waldenström macroglobulinemia

Clinical Trials & Observations
Irene M. Ghobrial, Federico Campigotto, Timothy J. Murphy, Erica N. Boswell, Ranjit Banwait, Feda Azab, Stacey Chuma, Janet Kunsman, Amanda Donovan, Farzana Masood, Diane Warren, Scott Rodig, Kenneth C. Anderson, Paul G. Richardson, Edie Weller, Jeffrey Matous
Journal: Blood
Blood (2013) 121 (8): 1296–1303.
https://doi.org/10.1182/blood-2012-06-439307
Published: 2013
Journal Articles

Preclinical activity, pharmacodynamic, and pharmacokinetic properties of a selective HDAC6 inhibitor, ACY-1215, in combination with bortezomib in multiple myeloma

Loredana Santo, Teru Hideshima, Andrew L. Kung, Jen-Chieh Tseng, David Tamang, Min Yang, Matthew Jarpe, John H. van Duzer, Ralph Mazitschek, Walter C. Ogier, Diana Cirstea, Scott Rodig, Homare Eda, Tyler Scullen, Miriam Canavese, James Bradner, Kenneth C. Anderson, Simon S. Jones, Noopur Raje
Journal: Blood
Blood (2012) 119 (11): 2579–2589.
https://doi.org/10.1182/blood-2011-10-387365
Published: 2012
Includes: Supplemental data
Journal Articles

Selective HDAC6 Inhibition Via ACY-1215, Either Alone or in Combination with Bortezomib, Restores Osteoblast Function and Suppresses Osteoclast Differentiation in Multiple Myeloma

Loredana Santo, MD, Teru Hideshima, MD, PhD, Andrew L. Kung, MD, PhD, Jen-Chieh Tseng, PhD, David Tamang, PhD, Min Yang, PhD, Matthew Jarpe, PhD, John H. van Duzer, PhD, Ralph Mazitschek, PhD, Diana Cirstea, MD, Homare Eda, MD, PhD, Tyler A. Scullen, BA, Scott Rodig, MD, PhD, Miriam Canavese, PhD, James Bradner, MD, Kenneth C Anderson, MD, Simon Jones, PhD, Noopur S. Raje, MD
Journal: Blood
Blood (2011) 118 (21): 2908.
https://doi.org/10.1182/blood.V118.21.2908.2908
Published: 2011
Journal Articles

Pharmacodynamic and Pharmacokinetic Properties of a Novel and Selective HDAC6 Inhibitor, ACY-1215, in Combination with Bortezomib in Multiple Myeloma

Loredana Santo, MD, Teru Hideshima, MD, PhD, Andrew L. Kung, MD, PhD, Jen-Chieh Tseng, PhD, David Tamang, PhD, Min Yang, PhD, Matthew Jarpe, PhD, John H. van Duzer, PhD, Ralph Mazitschek, PhD, Walter C Ogier, Diana D. Cirstea, MD, Scott Rodig, MD, PhD, Homare Eda, MD, PhD, Tyler A. Scullen, BA, Miriam Canavese, PhD, James E. Bradner, MD, Kenneth C Anderson, MD, Simon Jones, PhD, Noopur S. Raje, MD
Journal: Blood
Blood (2011) 118 (21): 2912.
https://doi.org/10.1182/blood.V118.21.2912.2912
Published: 2011
Journal Articles

Significant Biological Role of Sp1 Transactivation in Myeloma: Potential Therapeutic Application.

Mariateresa Fulciniti, PhD, Teru Hideshima, M.D., Ph.D., Puru Nanjappa, MS, Scott Rodig, M.D., Ph.D., Samir B Amin, MBBS, Dheeraj Pelluru, PhD, Jagannath Pal, Rao Prabhala, PhD, Masood A Shammas, PhD, Pierfrancesco Tassone, Scott Mohrland, Kenneth C. Anderson, MD, Nikhil C. Munshi
Journal: Blood
Blood (2009) 114 (22): 1841.
https://doi.org/10.1182/blood.V114.22.1841.1841
Published: 2009
Journal Articles

Combination of Nab -Rapamycin and Perifosine Induces Synergistic Cytotoxicity and Antitumor Activity Via Autophagy and Apoptosis in Multiple Myeloma (MM)

Diana Cirstea, M.D., Teru Hideshima, M.D., Ph.D., Samantha Pozzi, M.D., Sonia Vallet, M.D., Hiroshi Ikeda, M.D., Ph.D., Loredana Santo, M.D., Scott Rodig, M.D., Ph.D., Nileshwari Vaghela, M.B.S, Treeve Currie, Yutaka Okawa, M.D., Ph.D., Gaurav Chhetri, Chirayu G. Patel, Giulia Perrone, M.D., Gullu Gorgun, Ph.D., Elisabetta Calabrese, M.D., Voung Trieu, Neil Desai, Ph.D., Peter Sportelli, Nikhil C. Munshi, M.D., Kenneth C Anderson, M.D., Noopur Raje, M.D.
Journal: Blood
Blood (2008) 112 (11): 3663.
https://doi.org/10.1182/blood.V112.11.3663.3663
Published: 2008
Journal Articles

Molecular Profiling of Extramedullary and Medullary Plasmacytomas

Gabriela Motyckova, M.D., Ph.D., Aliyah Rahemtullah, M.D., Nileshwari Vaghela, M.S., Sonia Vallet, M.D., Adam Ackerman, Siddhartha Mukherjee, M.D., Ph.D., Samantha Pozzi, M.D., Loredana Santo, Ph.D., Diana Cirstea, M.D., Christiana Toomey, Ephraim P. Hochberg, M.D., Paola Dal Cin, Ph.D., Scott Rodig, M.D., Ph.D., Teru Hideshima, M.D., Ph.D., Kenneth C Anderson, M.D., Nikhil Munshi, M.D., Noopur Raje, M.D.
Journal: Blood
Blood (2008) 112 (11): 5111.
https://doi.org/10.1182/blood.V112.11.5111.5111
Published: 2008